subject
string
txt_report
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gold_diagnosis
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cognitive_txt
string
FTLD_203638978_01873_MR_Sagittal_MP-Rage_br_raw_20230206175220725_I10182269
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle maintains its normal volume without signs of enlargement - mild enlargement of the external csf - normal-to-mild bilateral lateral ventricle enlargement - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - no enlargement observed in the 4th ventricle For the cerebral cortex: - frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left) and supplementary motor cortex (normal-to-mild atrophy on the right) - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy on the right) and angular gyrus (normal-to-mild atrophy on the left) - occipital lobe maintains its normal morphology without atrophic features - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left), central operculum (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), entorhinal area (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the left) and fusiform gyrus (normal-to-mild atrophy on the left) For the subcortical structures: - caudate atrophy (mild on the left, normal-to-mild on the right) - the basal forebrain shows no structural abnormalities indicative of atrophy - amygdala presents with a healthy appearance, free from atrophy - putamen atrophy (normal-to-mild on the left, normal on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - accumbens atrophy (mild on the left, normal-to-mild on the right) - hippocampus atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral ventral dc atrophy
bvFTD
We have the following subject's personal information: - The subject is a male of 68.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. His standard CDR sum of boxes is 10.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203548350_03054_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178313
On a T1-weighted brain MRI we observed: For the ventricles: - no abnormal enlargement observed in the external csf - no enlargement observed in the 3rd ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - no enlargement observed in the lateral ventricle - no signs of enlargement detected in the 4th ventricle For the subcortical structures: - no observable atrophic alterations in the caudate - the thalamus shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the amygdala - pallidum appears structurally intact with no atrophic changes - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - the putamen shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral hippocampus atrophy - ventral dc remains normal, with no signs of tissue loss - no signs of atrophy detected in the accumbens For the cerebral cortex: - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle temporal gyrus (mild atrophy on the left) and inf. temporal gyrus (normal-to-mild atrophy on the right) - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the left) and posterior cingulate gyrus (normal-to-mild atrophy on the left) - parietal lobe maintains its normal morphology without atrophic features - insular cortex remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the occipital lobe - no signs of atrophy detected in the frontal lobe
CN
We have the following subject's personal information: - The subject is a female of 52.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203297245_03549_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450917
On a T1-weighted brain MRI we observed: For the ventricles: - normal-to-mild bilateral inf. lateral ventricle enlargement - lateral ventricle maintains its normal volume without signs of enlargement - mild enlargement of the external csf - normal-to-mild enlargement of the 4th ventricle - normal-to-mild enlargement of the 3rd ventricle For the subcortical structures: - hippocampus atrophy (mild on the left, normal-to-mild on the right) - ventral dc presents with a healthy appearance, free from atrophy - mild bilateral amygdala atrophy - putamen atrophy (mild on the left, normal-to-mild on the right) - basal forebrain remains normal, with no signs of tissue loss - mild bilateral accumbens atrophy - no observable atrophic alterations in the pallidum - caudate atrophy (mild on the left, normal-to-mild on the right) - thalamus presents with a healthy appearance, free from atrophy For the cerebral cortex: - limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), entorhinal area (normal-to-mild atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: sup. parietal lobule (normal-to-mild atrophy both left/right), angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy on the left), postcentral gyrus (normal-to-mild atrophy on the left) and postcentral gyrus medial segment (normal-to-mild atrophy on the right) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left/right), frontal pole (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus medial segment (normal-to-mild atrophy on the left), subcallosal area (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the insular cortex - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: occipital fusiform gyrus (normal-to-mild atrophy on the left), sup. occipital gyrus (normal-to-mild atrophy both left/right) and calcarine cortex (normal-to-mild atrophy on the right) - temporal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy both left/right), inf. temporal gyrus (mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy on the left), planum polare (normal-to-mild atrophy on the left), sup. temporal gyrus (normal-to-mild atrophy on the left) and transverse temporal gyrus (normal-to-mild atrophy on the right)
bvFTD
We have the following subject's personal information: - The subject is a male of 85.0 years old. - He has 17.0 years of education We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203679919_02917_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177143
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no pathological changes consistent with atrophy detected in the frontal lobe - no degenerative or atrophic changes noted in the occipital lobe - limbic cortex remains normal, with no signs of tissue loss - the temporal lobe shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the parietal lobe - no degenerative or atrophic changes noted in the insular cortex For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - no pathological changes consistent with enlargement noted in the 3rd ventricle - no abnormal enlargement observed in the external csf - no observable enlargement or abnormal growth in the lateral ventricle For the subcortical structures: - no degenerative or atrophic changes noted in the pallidum - ventral dc appears structurally intact with no atrophic changes - the accumbens shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral caudate atrophy - normal-to-mild bilateral putamen atrophy - basal forebrain presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the amygdala - no degenerative or atrophic changes noted in the hippocampus - no pathological changes consistent with atrophy detected in the thalamus
CN
We have the following subject's personal information: - The subject is a female of 29.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203250302_03205_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178289
On a T1-weighted brain MRI we observed: For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - normal-to-mild enlargement of the external csf - inf. lateral ventricle enlargement (normal on the left, mild on the right) - no enlargement observed in the 4th ventricle - normal-to-mild bilateral lateral ventricle enlargement For the cerebral cortex: - the occipital lobe shows no structural abnormalities indicative of atrophy - mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and moderate atrophy on the right), frontal operculum (normal-to-mild atrophy both left/right), posterior insula (normal-to-mild atrophy both left/right), central operculum (normal-to-mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left) - no signs of atrophy detected in the parietal lobe - limbic cortex atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and entorhinal area (normal-to-mild atrophy on the right) - frontal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: posterior orbital gyrus (mild atrophy both left/right), triangular inf. frontal gyrus (mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the right), gyrus rectus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the right) and precentral gyrus medial segment (normal-to-mild atrophy on the left) - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the right) For the subcortical structures: - basal forebrain presents with a healthy appearance, free from atrophy - hippocampus presents with a healthy appearance, free from atrophy - putamen atrophy (normal-to-mild on the left, mild on the right) - caudate atrophy (normal-to-mild on the left, mild on the right) - ventral dc remains normal, with no signs of tissue loss - accumbens atrophy (normal-to-mild on the left, mild on the right) - thalamus presents with a healthy appearance, free from atrophy - pallidum atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral amygdala atrophy
bvFTD
We have the following subject's personal information: - The subject is a female of 57.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203553373_03375_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450626
On a T1-weighted brain MRI we observed: For the ventricles: - no abnormal enlargement observed in the 3rd ventricle - external csf remains within normal size parameters, with no enlargement detected - no abnormal enlargement observed in the inf. lateral ventricle - no pathological changes consistent with enlargement noted in the 4th ventricle - lateral ventricle maintains its normal volume without signs of enlargement For the subcortical structures: - accumbens presents with a healthy appearance, free from atrophy - pallidum remains normal, with no signs of tissue loss - hippocampus atrophy (normal on the left, normal-to-mild on the right) - basal forebrain atrophy (normal on the left, mild on the right) - ventral dc atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the amygdala - no observable atrophic alterations in the putamen - no signs of atrophy detected in the thalamus - caudate appears structurally intact with no atrophic changes For the cerebral cortex: - no evidence of atrophy or degeneration in the temporal lobe - occipital lobe appears structurally intact with no atrophic changes - no observable atrophic alterations in the frontal lobe - no signs of atrophy detected in the parietal lobe - no observable atrophic alterations in the insular cortex - limbic cortex maintains its normal morphology without atrophic features
CN
We have the following subject's personal information: - The subject is a female of 57.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203651746_02645_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178160
On a T1-weighted brain MRI we observed: For the subcortical structures: - normal-to-mild bilateral accumbens atrophy - pallidum atrophy (mild on the left, normal-to-mild on the right) - mild bilateral putamen atrophy - no degenerative or atrophic changes noted in the ventral dc - basal forebrain appears structurally intact with no atrophic changes - normal-to-mild bilateral hippocampus atrophy - no signs of atrophy detected in the thalamus - caudate atrophy (normal-to-mild on the left, normal on the right) - amygdala atrophy (normal on the left, normal-to-mild on the right) For the cerebral cortex: - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: medial orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left) and sup. frontal gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the occipital lobe - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right), entorhinal area (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the left) and posterior cingulate gyrus (normal-to-mild atrophy on the left) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right) - no observable atrophic alterations in the parietal lobe - the temporal lobe shows no structural abnormalities indicative of atrophy For the ventricles: - normal-to-mild bilateral lateral ventricle enlargement - external csf maintains its normal volume without signs of enlargement - normal-to-mild enlargement of the 4th ventricle - no pathological changes consistent with enlargement noted in the 3rd ventricle - normal-to-mild bilateral inf. lateral ventricle enlargement
PNFA
We have the following subject's personal information: - The subject is a male of 66.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203841701_02104_MR_Sagittal_MP-Rage_br_raw_20230206154002708_I10181425
On a T1-weighted brain MRI we observed: For the subcortical structures: - normal-to-mild bilateral hippocampus atrophy - normal-to-mild bilateral caudate atrophy - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral accumbens atrophy - amygdala appears structurally intact with no atrophic changes - basal forebrain remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the thalamus - normal-to-mild bilateral ventral dc atrophy - mild bilateral putamen atrophy For the ventricles: - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild bilateral inf. lateral ventricle enlargement - no abnormal enlargement observed in the external csf - 4th ventricle remains within normal size parameters, with no enlargement detected - normal-to-mild enlargement of the 3rd ventricle For the cerebral cortex: - temporal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left), planum polare (normal-to-mild atrophy on the left), temporal pole (normal-to-mild atrophy on the right) and inf. temporal gyrus (normal-to-mild atrophy on the right) - the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus medial segment (mild atrophy on the right) and precuneus (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), parahippocampal gyrus (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the left) and anterior cingulate gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the right), central operculum (normal-to-mild atrophy on the left) and frontal operculum (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the frontal lobe - no degenerative or atrophic changes noted in the occipital lobe
bvFTD
We have the following subject's personal information: - The subject is a male of 68.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on behavior, comportment, and personality, corresponding to moderate impairment.
FTLD_203798684_02489_MR_Sagittal_MP-Rage_br_raw_20230209102705784_I10183481
On a T1-weighted brain MRI we observed: For the cerebral cortex: - insular cortex presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the frontal lobe - no evidence of atrophy or degeneration in the limbic cortex - no signs of atrophy detected in the parietal lobe - no degenerative or atrophic changes noted in the temporal lobe - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: occipital pole (normal-to-mild atrophy both left/right), lingual gyrus (normal-to-mild atrophy on the right) and inf. occipital gyrus (normal-to-mild atrophy on the right) For the ventricles: - no abnormal enlargement observed in the external csf - the 4th ventricle shows no structural abnormalities indicative of enlargement - 3rd ventricle remains within normal size parameters, with no enlargement detected - no abnormal enlargement observed in the lateral ventricle - no pathological changes consistent with enlargement noted in the inf. lateral ventricle For the subcortical structures: - no observable atrophic alterations in the pallidum - ventral dc atrophy (normal on the left, normal-to-mild on the right) - no signs of atrophy detected in the accumbens - the putamen shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the thalamus - no observable atrophic alterations in the hippocampus - amygdala atrophy (normal-to-mild on the left, normal on the right) - no signs of atrophy detected in the caudate - no signs of atrophy detected in the basal forebrain
CN
We have the following subject's personal information: - The subject is a female of 31.0 years old. - She has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203667799_01996_MR_Sagittal_MP-Rage_br_raw_20230206175849666_I10182317
On a T1-weighted brain MRI we observed: For the cerebral cortex: - temporal lobe presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the occipital lobe - insular cortex presents with a healthy appearance, free from atrophy - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the left), gyrus rectus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) and triangular inf. frontal gyrus (normal-to-mild atrophy on the left) - no evidence of atrophy or degeneration in the limbic cortex - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy on the right), precuneus (normal-to-mild atrophy on the left) and sup. parietal lobule (normal-to-mild atrophy on the left) For the ventricles: - inf. lateral ventricle is free from enlargement or excessive growth - no enlargement observed in the 3rd ventricle - normal-to-mild enlargement of the 4th ventricle - external csf maintains its normal volume without signs of enlargement - lateral ventricle enlargement (normal on the left, normal-to-mild on the right) For the subcortical structures: - accumbens appears structurally intact with no atrophic changes - normal-to-mild bilateral thalamus atrophy - normal-to-mild bilateral putamen atrophy - no signs of atrophy detected in the hippocampus - basal forebrain maintains its normal morphology without atrophic features - ventral dc remains normal, with no signs of tissue loss - normal-to-mild bilateral pallidum atrophy - no pathological changes consistent with atrophy detected in the caudate - no pathological changes consistent with atrophy detected in the amygdala
CN
We have the following subject's personal information: - The subject is a female of 18.0 years old. - She has 13.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203202458_03850_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047833
On a T1-weighted brain MRI we observed: For the cerebral cortex: - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right), parahippocampal gyrus (normal-to-mild atrophy on the left) and entorhinal area (normal-to-mild atrophy on the left) - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. frontal gyrus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left) and supplementary motor cortex (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the insular cortex - no pathological changes consistent with atrophy detected in the occipital lobe - no pathological changes consistent with atrophy detected in the parietal lobe - temporal lobe remains normal, with no signs of tissue loss For the subcortical structures: - no evidence of atrophy or degeneration in the pallidum - caudate atrophy (normal on the left, normal-to-mild on the right) - no observable atrophic alterations in the putamen - amygdala atrophy (mild on the left, normal-to-mild on the right) - thalamus appears structurally intact with no atrophic changes - hippocampus atrophy (normal-to-mild on the left, normal on the right) - accumbens atrophy (normal-to-mild on the left, normal on the right) - basal forebrain maintains its normal morphology without atrophic features - no observable atrophic alterations in the ventral dc For the ventricles: - normal-to-mild bilateral inf. lateral ventricle enlargement - no pathological changes consistent with enlargement noted in the external csf - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - the 4th ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the 3rd ventricle
bvFTD
We have the following subject's personal information: - The subject is a female of 62.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203323082_01282_MR_Sagittal_MP-Rage_br_raw_20230206170858711_I10181945
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the frontal lobe shows no structural abnormalities indicative of atrophy - the occipital lobe shows no structural abnormalities indicative of atrophy - temporal lobe remains normal, with no signs of tissue loss - insular cortex presents with a healthy appearance, free from atrophy, with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), frontal operculum (normal-to-mild atrophy on the right) and central operculum (normal-to-mild atrophy on the left) - no observable atrophic alterations in the parietal lobe - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy both left/right), entorhinal area (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) For the subcortical structures: - normal-to-mild bilateral putamen atrophy - no pathological changes consistent with atrophy detected in the basal forebrain - normal-to-mild bilateral accumbens atrophy - no observable atrophic alterations in the hippocampus - no degenerative or atrophic changes noted in the thalamus - amygdala atrophy (normal on the left, normal-to-mild on the right) - ventral dc maintains its normal morphology without atrophic features - normal-to-mild bilateral caudate atrophy - pallidum remains normal, with no signs of tissue loss For the ventricles: - no pathological changes consistent with enlargement noted in the external csf - 4th ventricle is free from enlargement or excessive growth - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - no abnormal enlargement observed in the 3rd ventricle - no abnormal enlargement observed in the lateral ventricle
CN
We have the following subject's personal information: - The subject is a male of 40.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203295674_02479_MR_Sagittal_MP-Rage_br_raw_20230209102621318_I10183479
On a T1-weighted brain MRI we observed: For the subcortical structures: - no observable atrophic alterations in the accumbens - no pathological changes consistent with atrophy detected in the putamen - no degenerative or atrophic changes noted in the hippocampus - no pathological changes consistent with atrophy detected in the thalamus - caudate maintains its normal morphology without atrophic features - amygdala remains normal, with no signs of tissue loss - ventral dc appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the basal forebrain - no pathological changes consistent with atrophy detected in the pallidum For the cerebral cortex: - occipital lobe remains normal, with no signs of tissue loss - parietal lobe presents with a healthy appearance, free from atrophy - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in triangular inf. frontal gyrus (mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) - limbic cortex maintains its normal morphology without atrophic features - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left) - no pathological changes consistent with atrophy detected in the temporal lobe For the ventricles: - no pathological changes consistent with enlargement noted in the inf. lateral ventricle - 3rd ventricle remains within normal size parameters, with no enlargement detected - no enlargement observed in the lateral ventricle - no signs of enlargement detected in the 4th ventricle - external csf remains within normal size parameters, with no enlargement detected
CN
We have the following subject's personal information: - The subject is a female of 39.0 years old. - She has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203234178_02873_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176394
On a T1-weighted brain MRI we observed: For the subcortical structures: - putamen remains normal, with no signs of tissue loss - accumbens atrophy (normal-to-mild on the left, normal on the right) - basal forebrain atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral hippocampus atrophy - thalamus maintains its normal morphology without atrophic features - normal-to-mild bilateral ventral dc atrophy - normal-to-mild bilateral caudate atrophy - amygdala appears structurally intact with no atrophic changes - normal-to-mild bilateral pallidum atrophy For the cerebral cortex: - no signs of atrophy detected in the frontal lobe - no pathological changes consistent with atrophy detected in the insular cortex - the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and posterior cingulate gyrus (normal-to-mild atrophy on the left) - no signs of atrophy detected in the parietal lobe - the temporal lobe shows no structural abnormalities indicative of atrophy - the occipital lobe shows no structural abnormalities indicative of atrophy For the ventricles: - lateral ventricle maintains its normal volume without signs of enlargement - external csf appears structurally intact, with no evidence of enlargement - no abnormal enlargement observed in the 4th ventricle - normal-to-mild enlargement of the 3rd ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
CN
We have the following subject's personal information: - The subject is a male of 79.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203734411_01113_MR_Sagittal_MP-Rage_br_raw_20230206165755354_I10181857
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no pathological changes consistent with atrophy detected in the parietal lobe - no degenerative or atrophic changes noted in the frontal lobe - temporal lobe presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the limbic cortex - no degenerative or atrophic changes noted in the occipital lobe - insular cortex presents with a healthy appearance, free from atrophy For the ventricles: - no observable enlargement or abnormal growth in the external csf - no abnormal enlargement observed in the 4th ventricle - 3rd ventricle remains within normal size parameters, with no enlargement detected - no abnormal enlargement observed in the lateral ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement For the subcortical structures: - putamen atrophy (normal on the left, normal-to-mild on the right) - no observable atrophic alterations in the amygdala - hippocampus appears structurally intact with no atrophic changes - normal-to-mild bilateral ventral dc atrophy - no signs of atrophy detected in the thalamus - no pathological changes consistent with atrophy detected in the pallidum - basal forebrain remains normal, with no signs of tissue loss - accumbens remains normal, with no signs of tissue loss - no signs of atrophy detected in the caudate
bvFTD
We have the following subject's personal information: - The subject is a female of 64.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203920267_03762_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451137
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral caudate atrophy - basal forebrain appears structurally intact with no atrophic changes - normal-to-mild bilateral thalamus atrophy - normal-to-mild bilateral amygdala atrophy - ventral dc atrophy (normal-to-mild on the left, normal on the right) - mild bilateral accumbens atrophy - mild bilateral putamen atrophy - mild bilateral pallidum atrophy - normal-to-mild bilateral hippocampus atrophy For the ventricles: - 4th ventricle appears structurally intact, with no evidence of enlargement - normal-to-mild enlargement of the 3rd ventricle - mild enlargement of the external csf - mild bilateral inf. lateral ventricle enlargement - normal-to-mild bilateral lateral ventricle enlargement For the cerebral cortex: - no degenerative or atrophic changes noted in the occipital lobe - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), posterior insula (normal-to-mild atrophy both left/right), central operculum (normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left) - mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the left) and sup. frontal gyrus (normal-to-mild atrophy on the right) - no evidence of atrophy or degeneration in the temporal lobe - the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus medial segment (mild atrophy on the right) and postcentral gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the right) and anterior cingulate gyrus (normal-to-mild atrophy both left/right)
bvFTD
We have the following subject's personal information: - The subject is a male of 66.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 4.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203937786_03683_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047668
On a T1-weighted brain MRI we observed: For the cerebral cortex: - temporal lobe appears structurally intact with no atrophic changes - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left), gyrus rectus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left) and sup. frontal gyrus (normal-to-mild atrophy on the right) - occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: occipital fusiform gyrus (normal-to-mild atrophy both left/right), middle occipital gyrus (normal-to-mild atrophy on the left) and calcarine cortex (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the insular cortex - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the parietal lobe For the subcortical structures: - no pathological changes consistent with atrophy detected in the putamen - normal-to-mild bilateral accumbens atrophy - no pathological changes consistent with atrophy detected in the ventral dc - no pathological changes consistent with atrophy detected in the hippocampus - normal-to-mild bilateral caudate atrophy - the thalamus shows no structural abnormalities indicative of atrophy - the pallidum shows no structural abnormalities indicative of atrophy - the basal forebrain shows no structural abnormalities indicative of atrophy - amygdala atrophy (normal-to-mild on the left, normal on the right) For the ventricles: - no abnormal enlargement observed in the 3rd ventricle - 4th ventricle appears structurally intact, with no evidence of enlargement - external csf maintains its normal volume without signs of enlargement - no enlargement observed in the lateral ventricle - inf. lateral ventricle maintains its normal volume without signs of enlargement
bvFTD
We have the following subject's personal information: - The subject is a female of 60.0 years old. - She has 11.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 3.0, corresponding to severe impairment. Her standard CDR sum of boxes is 16.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203788719_01918_MR_Sagittal_MP-Rage_br_raw_20230206152255569_I10181377
On a T1-weighted brain MRI we observed: For the ventricles: - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - no signs of enlargement detected in the 4th ventricle - inf. lateral ventricle maintains its normal volume without signs of enlargement - no abnormal enlargement observed in the external csf - no pathological changes consistent with enlargement noted in the 3rd ventricle For the cerebral cortex: - parietal lobe presents with a healthy appearance, free from atrophy - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left) and posterior orbital gyrus (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the temporal lobe - insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left) - the limbic cortex shows no structural abnormalities indicative of atrophy - occipital lobe maintains its normal morphology without atrophic features For the subcortical structures: - no pathological changes consistent with atrophy detected in the ventral dc - normal-to-mild bilateral putamen atrophy - no degenerative or atrophic changes noted in the thalamus - hippocampus remains normal, with no signs of tissue loss - amygdala presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the accumbens - no evidence of atrophy or degeneration in the pallidum - no pathological changes consistent with atrophy detected in the basal forebrain - caudate maintains its normal morphology without atrophic features
PNFA
We have the following subject's personal information: - The subject is a female of 75.0 years old. - She has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203966690_02096_MR_Sagittal_MP-Rage_br_raw_20230206153820313_I10181422
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evidence of atrophy or degeneration in the amygdala - normal-to-mild bilateral thalamus atrophy - no observable atrophic alterations in the basal forebrain - pallidum atrophy (normal on the left, normal-to-mild on the right) - accumbens remains normal, with no signs of tissue loss - hippocampus atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral ventral dc atrophy - caudate remains normal, with no signs of tissue loss - the putamen shows no structural abnormalities indicative of atrophy For the cerebral cortex: - no degenerative or atrophic changes noted in the insular cortex - no signs of atrophy detected in the limbic cortex - no degenerative or atrophic changes noted in the frontal lobe - no signs of atrophy detected in the temporal lobe - occipital lobe remains normal, with no signs of tissue loss - parietal lobe remains normal, with no signs of tissue loss For the ventricles: - no abnormal enlargement observed in the 4th ventricle - normal-to-mild bilateral inf. lateral ventricle enlargement - external csf is free from enlargement or excessive growth - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - 3rd ventricle appears structurally intact, with no evidence of enlargement
CN
We have the following subject's personal information: - The subject is a female of 34.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203169386_01686_MR_Sagittal_MP-Rage_br_raw_20230206173952621_I10182174
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral thalamus atrophy - mild bilateral putamen atrophy - no degenerative or atrophic changes noted in the basal forebrain - mild bilateral pallidum atrophy - normal-to-mild bilateral hippocampus atrophy - mild bilateral accumbens atrophy - amygdala atrophy (mild on the left, normal-to-mild on the right) - mild bilateral caudate atrophy - ventral dc atrophy (normal-to-mild on the left, normal on the right) For the ventricles: - 4th ventricle appears structurally intact, with no evidence of enlargement - normal-to-mild bilateral inf. lateral ventricle enlargement - mild enlargement of the 3rd ventricle - mild bilateral lateral ventricle enlargement - mild enlargement of the external csf For the cerebral cortex: - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy both left/right) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: triangular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the right) - no pathological changes consistent with atrophy detected in the parietal lobe - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy both left/right), transverse temporal gyrus (normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left) and temporal pole (normal-to-mild atrophy on the left) - the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the right) - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), cuneus (normal-to-mild atrophy on the right), occipital fusiform gyrus (normal-to-mild atrophy on the right), inf. occipital gyrus (normal-to-mild atrophy on the left) and occipital pole (normal-to-mild atrophy on the right)
bvFTD
We have the following subject's personal information: - The subject is a female of 56.0 years old. - She has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203240205_03504_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450857
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the external csf - no signs of enlargement detected in the 3rd ventricle - lateral ventricle appears structurally intact, with no evidence of enlargement - no signs of enlargement detected in the 4th ventricle - no enlargement observed in the inf. lateral ventricle For the subcortical structures: - hippocampus maintains its normal morphology without atrophic features - normal-to-mild bilateral caudate atrophy - normal-to-mild bilateral accumbens atrophy - the amygdala shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral pallidum atrophy - ventral dc atrophy (normal-to-mild on the left, normal on the right) - no evidence of atrophy or degeneration in the basal forebrain - no pathological changes consistent with atrophy detected in the putamen - normal-to-mild bilateral thalamus atrophy For the cerebral cortex: - temporal lobe remains normal, with no signs of tissue loss - frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: medial frontal cortex (normal-to-mild atrophy both left/right), frontal pole (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus (normal-to-mild atrophy on the left), subcallosal area (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the left) and posterior orbital gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the insular cortex - occipital lobe presents with a healthy appearance, free from atrophy - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left) - parietal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy both left/right), supramarginal gyrus (normal-to-mild atrophy on the left), postcentral gyrus medial segment (normal-to-mild atrophy both left/right), angular gyrus (normal-to-mild atrophy both left/right), postcentral gyrus (normal-to-mild atrophy on the left) and sup. parietal lobule (normal-to-mild atrophy on the left)
PNFA
We have the following subject's personal information: - The subject is a female of 80.0 years old. - She has 15.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203411700_03001_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450139
On a T1-weighted brain MRI we observed: For the ventricles: - inf. lateral ventricle maintains its normal volume without signs of enlargement - the 4th ventricle shows no structural abnormalities indicative of enlargement - 3rd ventricle is free from enlargement or excessive growth - lateral ventricle maintains its normal volume without signs of enlargement - normal-to-mild enlargement of the external csf For the cerebral cortex: - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy both left/right) and posterior cingulate gyrus (normal-to-mild atrophy on the right) - no observable atrophic alterations in the occipital lobe - frontal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left), frontal pole (normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the right) - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left) and temporal pole (normal-to-mild atrophy on the left) - parietal lobe maintains its normal morphology without atrophic features - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), posterior insula (normal-to-mild atrophy both left/right) and central operculum (normal-to-mild atrophy on the right) For the subcortical structures: - no observable atrophic alterations in the hippocampus - accumbens atrophy (normal on the left, normal-to-mild on the right) - amygdala remains normal, with no signs of tissue loss - basal forebrain presents with a healthy appearance, free from atrophy - caudate atrophy (normal-to-mild on the left, mild on the right) - normal-to-mild bilateral putamen atrophy - no pathological changes consistent with atrophy detected in the thalamus - pallidum atrophy (normal on the left, normal-to-mild on the right) - no observable atrophic alterations in the ventral dc
PNFA
We have the following subject's personal information: - The subject is a female of 70.0 years old. - She has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203154389_01985_MR_Sagittal_MP-Rage_br_raw_20230209094208557_I10183246
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral thalamus atrophy - mild bilateral accumbens atrophy - normal-to-mild bilateral pallidum atrophy - basal forebrain appears structurally intact with no atrophic changes - hippocampus atrophy (normal-to-mild on the left, normal on the right) - amygdala atrophy (mild on the left, normal-to-mild on the right) - no degenerative or atrophic changes noted in the ventral dc - normal-to-mild bilateral putamen atrophy - normal-to-mild bilateral caudate atrophy For the cerebral cortex: - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), lateral orbital gyrus (mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the right) and precentral gyrus medial segment (normal-to-mild atrophy on the left) - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: cuneus (normal-to-mild atrophy both left/right), lingual gyrus (normal-to-mild atrophy on the left), occipital pole (normal-to-mild atrophy on the right) and inf. occipital gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy both left/right) and entorhinal area (normal-to-mild atrophy both left/right) - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy both left/right), postcentral gyrus (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), planum polare (normal-to-mild atrophy both left/right), inf. temporal gyrus (normal-to-mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the right) - mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), anterior insula (normal-to-mild atrophy both left/right), posterior insula (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy on the right) For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - no abnormal enlargement observed in the 4th ventricle - inf. lateral ventricle enlargement (moderate on the left, mild on the right) - mild bilateral lateral ventricle enlargement - mild enlargement of the external csf
bvFTD
We have the following subject's personal information: - The subject is a male of 52.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203297550_03059_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178271
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the parietal lobe shows no structural abnormalities indicative of atrophy - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: precentral gyrus (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) - no evidence of atrophy or degeneration in the temporal lobe - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the right) - insular cortex presents with a healthy appearance, free from atrophy - the occipital lobe shows no structural abnormalities indicative of atrophy For the subcortical structures: - accumbens atrophy (normal on the left, normal-to-mild on the right) - caudate atrophy (normal on the left, normal-to-mild on the right) - amygdala atrophy (normal on the left, normal-to-mild on the right) - hippocampus maintains its normal morphology without atrophic features - no signs of atrophy detected in the basal forebrain - pallidum atrophy (normal-to-mild on the left, mild on the right) - normal-to-mild bilateral ventral dc atrophy - normal-to-mild bilateral putamen atrophy - no pathological changes consistent with atrophy detected in the thalamus For the ventricles: - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - mild enlargement of the external csf - no pathological changes consistent with enlargement noted in the 4th ventricle - no pathological changes consistent with enlargement noted in the lateral ventricle - no signs of enlargement detected in the 3rd ventricle
bvFTD
We have the following subject's personal information: - The subject is a female of 66.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203098865_03569_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450937
On a T1-weighted brain MRI we observed: For the cerebral cortex: - limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right), entorhinal area (mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the right) and posterior cingulate gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), frontal operculum (normal-to-mild atrophy both left/right) and posterior insula (normal-to-mild atrophy both left/right) - frontal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), frontal pole (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy both left/right) and sup. frontal gyrus (normal-to-mild atrophy on the right) - no observable atrophic alterations in the temporal lobe - no pathological changes consistent with atrophy detected in the parietal lobe - the occipital lobe shows no structural abnormalities indicative of atrophy For the ventricles: - normal-to-mild enlargement of the external csf - no signs of enlargement detected in the 4th ventricle - severe bilateral inf. lateral ventricle enlargement - mild enlargement of the 3rd ventricle - lateral ventricle enlargement (moderate on the left, mild on the right) For the subcortical structures: - basal forebrain maintains its normal morphology without atrophic features - mild bilateral putamen atrophy - accumbens atrophy (moderate on the left, mild on the right) - caudate atrophy (moderate on the left, mild on the right) - amygdala atrophy (mild on the left, moderate on the right) - normal-to-mild bilateral ventral dc atrophy - pallidum atrophy (mild on the left, normal-to-mild on the right) - mild bilateral thalamus atrophy - hippocampus atrophy (mild on the left, moderate on the right)
bvFTD
We have the following subject's personal information: - The subject is a male of 60.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 6.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203724047_02742_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176933
On a T1-weighted brain MRI we observed: For the cerebral cortex: - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), posterior insula (normal-to-mild atrophy both left/right), frontal operculum (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the right) - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: posterior orbital gyrus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) and supplementary motor cortex (normal-to-mild atrophy on the left) - occipital lobe remains normal, with no signs of tissue loss - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy both left/right), transverse temporal gyrus (mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left) and planum temporale (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the parietal lobe - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy both left/right), entorhinal area (normal-to-mild atrophy both left/right) and anterior cingulate gyrus (normal-to-mild atrophy on the right) For the subcortical structures: - accumbens atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral thalamus atrophy - normal-to-mild bilateral pallidum atrophy - ventral dc maintains its normal morphology without atrophic features - caudate presents with a healthy appearance, free from atrophy - normal-to-mild bilateral basal forebrain atrophy - the amygdala shows no structural abnormalities indicative of atrophy - mild bilateral putamen atrophy - normal-to-mild bilateral hippocampus atrophy For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - mild enlargement of the 3rd ventricle - mild bilateral inf. lateral ventricle enlargement - external csf is free from enlargement or excessive growth - mild bilateral lateral ventricle enlargement
bvFTD
We have the following subject's personal information: - The subject is a male of 79.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203260125_02526_MR_Sagittal_MP-Rage_br_raw_20230206161248652_I10181566
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no signs of atrophy detected in the limbic cortex - the parietal lobe shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: occipital fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and cuneus (normal-to-mild atrophy both left/right) - mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: precentral gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy both left/right), frontal pole (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) and medial orbital gyrus (normal-to-mild atrophy on the right) - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy both left/right), transverse temporal gyrus (normal-to-mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: parietal operculum (normal-to-mild atrophy both left/right), frontal operculum (normal-to-mild atrophy both left/right) and central operculum (normal-to-mild atrophy on the right) For the subcortical structures: - no signs of atrophy detected in the putamen - no observable atrophic alterations in the amygdala - no evidence of atrophy or degeneration in the hippocampus - caudate atrophy (normal-to-mild on the left, mild on the right) - normal-to-mild bilateral thalamus atrophy - pallidum appears structurally intact with no atrophic changes - ventral dc atrophy (normal on the left, normal-to-mild on the right) - basal forebrain remains normal, with no signs of tissue loss - normal-to-mild bilateral accumbens atrophy For the ventricles: - mild bilateral inf. lateral ventricle enlargement - normal-to-mild bilateral lateral ventricle enlargement - mild enlargement of the 3rd ventricle - normal-to-mild enlargement of the 4th ventricle - mild enlargement of the external csf
PNFA
We have the following subject's personal information: - The subject is a female of 78.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203808293_02390_MR_Sagittal_MP-Rage_br_raw_20230206180655212_I10182372
On a T1-weighted brain MRI we observed: For the ventricles: - no signs of enlargement detected in the external csf - no signs of enlargement detected in the 4th ventricle - no signs of enlargement detected in the 3rd ventricle - no pathological changes consistent with enlargement noted in the lateral ventricle - inf. lateral ventricle is free from enlargement or excessive growth For the subcortical structures: - ventral dc maintains its normal morphology without atrophic features - putamen remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the thalamus - hippocampus remains normal, with no signs of tissue loss - normal-to-mild bilateral caudate atrophy - no degenerative or atrophic changes noted in the pallidum - the amygdala shows no structural abnormalities indicative of atrophy - accumbens maintains its normal morphology without atrophic features - no observable atrophic alterations in the basal forebrain For the cerebral cortex: - no signs of atrophy detected in the frontal lobe - no degenerative or atrophic changes noted in the occipital lobe - parietal lobe remains normal, with no signs of tissue loss - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the left), temporal pole (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the left) - the limbic cortex shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the insular cortex
CN
We have the following subject's personal information: - The subject is a female of 57.0 years old. - She has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203161564_02466_MR_Sagittal_MP-Rage_br_raw_20230206160810454_I10181547
On a T1-weighted brain MRI we observed: For the subcortical structures: - no pathological changes consistent with atrophy detected in the ventral dc - amygdala remains normal, with no signs of tissue loss - no observable atrophic alterations in the accumbens - no signs of atrophy detected in the thalamus - hippocampus presents with a healthy appearance, free from atrophy - putamen appears structurally intact with no atrophic changes - basal forebrain remains normal, with no signs of tissue loss - pallidum presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the caudate For the ventricles: - the 3rd ventricle shows no structural abnormalities indicative of enlargement - no pathological changes consistent with enlargement noted in the inf. lateral ventricle - no enlargement observed in the 4th ventricle - no observable enlargement or abnormal growth in the lateral ventricle - normal-to-mild enlargement of the external csf For the cerebral cortex: - no evidence of atrophy or degeneration in the occipital lobe - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: precentral gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy on the left) and sup. frontal gyrus (normal-to-mild atrophy on the left) - insular cortex presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the parietal lobe - temporal lobe maintains its normal morphology without atrophic features - no signs of atrophy detected in the limbic cortex
CN
We have the following subject's personal information: - The subject is a male of 44.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203765060_03066_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178114
On a T1-weighted brain MRI we observed: For the subcortical structures: - caudate atrophy (mild on the left, normal on the right) - no evidence of atrophy or degeneration in the hippocampus - no signs of atrophy detected in the basal forebrain - pallidum atrophy (mild on the left, normal on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - accumbens atrophy (mild on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the ventral dc - amygdala atrophy (moderate on the left, normal-to-mild on the right) - putamen atrophy (mild on the left, normal on the right) For the ventricles: - normal-to-mild enlargement of the 4th ventricle - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - inf. lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild enlargement of the external csf - mild enlargement of the 3rd ventricle For the cerebral cortex: - the occipital lobe shows no structural abnormalities indicative of atrophy - parietal lobe remains normal, with no signs of tissue loss - limbic cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), entorhinal area (mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left), frontal operculum (normal-to-mild atrophy on the left), posterior insula (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left) - frontal lobe remains normal, with no signs of tissue loss - temporal lobe atrophy (moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left), fusiform gyrus (mild atrophy on the left) and planum polare (normal-to-mild atrophy on the left)
bvFTD
We have the following subject's personal information: - The subject is a male of 67.0 years old. - He has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203538720_01023_MR_Sagittal_MP-Rage_br_raw_20230206164347404_I10181749
On a T1-weighted brain MRI we observed: For the ventricles: - no abnormal enlargement observed in the lateral ventricle - 3rd ventricle is free from enlargement or excessive growth - no observable enlargement or abnormal growth in the external csf - no signs of enlargement detected in the 4th ventricle - no observable enlargement or abnormal growth in the inf. lateral ventricle For the subcortical structures: - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral caudate atrophy - normal-to-mild bilateral ventral dc atrophy - thalamus remains normal, with no signs of tissue loss - hippocampus remains normal, with no signs of tissue loss - no observable atrophic alterations in the amygdala - normal-to-mild bilateral putamen atrophy - basal forebrain presents with a healthy appearance, free from atrophy - accumbens remains normal, with no signs of tissue loss For the cerebral cortex: - no observable atrophic alterations in the limbic cortex - no pathological changes consistent with atrophy detected in the frontal lobe - no evidence of atrophy or degeneration in the occipital lobe - no signs of atrophy detected in the temporal lobe - the parietal lobe shows no structural abnormalities indicative of atrophy - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), frontal operculum (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left)
CN
We have the following subject's personal information: - The subject is a female of 59.0 years old. - She has 17.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203726286_01682_MR_Sagittal_MP-Rage_br_raw_20230206150107788_I10181316
On a T1-weighted brain MRI we observed: For the cerebral cortex: - insular cortex presents with a healthy appearance, free from atrophy - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the right) - no pathological changes consistent with atrophy detected in the occipital lobe - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: supramarginal gyrus (normal-to-mild atrophy both left/right), angular gyrus (normal-to-mild atrophy on the left), postcentral gyrus medial segment (normal-to-mild atrophy on the right), postcentral gyrus (normal-to-mild atrophy on the left) and sup. parietal lobule (normal-to-mild atrophy on the right) - temporal lobe maintains its normal morphology without atrophic features - no observable atrophic alterations in the frontal lobe For the ventricles: - 4th ventricle appears structurally intact, with no evidence of enlargement - the external csf shows no structural abnormalities indicative of enlargement - the lateral ventricle shows no structural abnormalities indicative of enlargement - no observable enlargement or abnormal growth in the inf. lateral ventricle - no signs of enlargement detected in the 3rd ventricle For the subcortical structures: - no evidence of atrophy or degeneration in the pallidum - hippocampus atrophy (normal on the left, normal-to-mild on the right) - accumbens maintains its normal morphology without atrophic features - caudate maintains its normal morphology without atrophic features - amygdala presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the putamen - the thalamus shows no structural abnormalities indicative of atrophy - ventral dc presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the basal forebrain
CN
We have the following subject's personal information: - The subject is a female of 71.0 years old. - She has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203403944_02440_MR_Sagittal_MP-Rage_br_raw_20230206180813340_I10182378
On a T1-weighted brain MRI we observed: For the subcortical structures: - caudate atrophy (moderate on the left, mild on the right) - amygdala atrophy (severe on the left, moderate on the right) - no signs of atrophy detected in the basal forebrain - hippocampus atrophy (moderate on the left, mild on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - ventral dc atrophy (normal-to-mild on the left, normal on the right) - putamen atrophy (moderate on the left, mild on the right) - pallidum atrophy (mild on the left, normal-to-mild on the right) - moderate bilateral accumbens atrophy For the cerebral cortex: - mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right), posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left) - temporal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the right) - no pathological changes consistent with atrophy detected in the parietal lobe - mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (mild atrophy both left/right), anterior cingulate gyrus (mild atrophy both left/right), parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy both left/right) - occipital lobe presents with a healthy appearance, free from atrophy - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) For the ventricles: - normal-to-mild enlargement of the external csf - inf. lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild enlargement of the 3rd ventricle - normal-to-mild bilateral lateral ventricle enlargement - no pathological changes consistent with enlargement noted in the 4th ventricle
bvFTD
We have the following subject's personal information: - The subject is a male of 62.0 years old. - He has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203568133_01336_MR_Sagittal_MP-Rage_br_raw_20230206172305267_I10182049
On a T1-weighted brain MRI we observed: For the cerebral cortex: - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the left) - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: frontal operculum (mild atrophy on the left), anterior insula (normal-to-mild atrophy on the left) and central operculum (normal-to-mild atrophy on the right) - mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy both left/right), lateral orbital gyrus (mild atrophy on the left), sup. frontal gyrus (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left) and medial orbital gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the occipital lobe - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. temporal gyrus (mild atrophy on the left), temporal pole (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left) and fusiform gyrus (normal-to-mild atrophy on the right) For the ventricles: - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (mild on the left, normal on the right) - normal-to-mild enlargement of the external csf - no signs of enlargement detected in the 4th ventricle For the subcortical structures: - caudate atrophy (mild on the left, normal-to-mild on the right) - basal forebrain remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the amygdala - hippocampus atrophy (normal-to-mild on the left, normal on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - ventral dc atrophy (mild on the left, normal-to-mild on the right) - pallidum atrophy (mild on the left, normal-to-mild on the right) - normal-to-mild bilateral putamen atrophy - accumbens atrophy (normal-to-mild on the left, normal on the right)
bvFTD
We have the following subject's personal information: - The subject is a male of 73.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203155355_03555_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450924
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the parietal lobe shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy on the left), anterior cingulate gyrus (normal-to-mild atrophy on the right) and posterior cingulate gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: medial frontal cortex (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left) and sup. frontal gyrus (normal-to-mild atrophy on the right) - temporal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy both left/right), inf. temporal gyrus (normal-to-mild atrophy both left/right), transverse temporal gyrus (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy both left/right), frontal operculum (normal-to-mild atrophy both left/right), parietal operculum (normal-to-mild atrophy both left/right), posterior insula (normal-to-mild atrophy on the left) and anterior insula (normal-to-mild atrophy on the left) - occipital lobe appears structurally intact with no atrophic changes For the subcortical structures: - no evidence of atrophy or degeneration in the basal forebrain - no pathological changes consistent with atrophy detected in the hippocampus - no signs of atrophy detected in the pallidum - thalamus presents with a healthy appearance, free from atrophy - accumbens atrophy (normal-to-mild on the left, normal on the right) - putamen presents with a healthy appearance, free from atrophy - amygdala atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the ventral dc - caudate maintains its normal morphology without atrophic features For the ventricles: - external csf is free from enlargement or excessive growth - normal-to-mild enlargement of the 4th ventricle - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral lateral ventricle enlargement
bvFTD
We have the following subject's personal information: - The subject is a male of 52.0 years old. - He has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on behavior, comportment, and personality, corresponding to moderate impairment.
FTLD_203985877_03778_MR_Accelerated_Sagittal_MPRAGE_br_raw_20250_I11137580
On a T1-weighted brain MRI we observed: For the subcortical structures: - thalamus atrophy (normal-to-mild on the left, normal on the right) - hippocampus atrophy (normal-to-mild on the left, normal on the right) - putamen atrophy (normal-to-mild on the left, normal on the right) - accumbens atrophy (normal-to-mild on the left, normal on the right) - the basal forebrain shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the caudate - amygdala atrophy (normal-to-mild on the left, normal on the right) - ventral dc appears structurally intact with no atrophic changes - no signs of atrophy detected in the pallidum For the ventricles: - external csf remains within normal size parameters, with no enlargement detected - 4th ventricle maintains its normal volume without signs of enlargement - lateral ventricle remains within normal size parameters, with no enlargement detected - the 3rd ventricle shows no structural abnormalities indicative of enlargement - inf. lateral ventricle enlargement (mild on the left, normal on the right) For the cerebral cortex: - temporal lobe atrophy (moderate on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left), sup. temporal gyrus (normal-to-mild atrophy both left/right) and transverse temporal gyrus (normal-to-mild atrophy on the right) - frontal lobe appears structurally intact with no atrophic changes - parietal lobe presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the limbic cortex - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right) and central operculum (normal-to-mild atrophy on the right) - no observable atrophic alterations in the occipital lobe
SD
We have the following subject's personal information: - The subject is a female of 69.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203354466_02665_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177781
On a T1-weighted brain MRI we observed: For the subcortical structures: - putamen atrophy (normal-to-mild on the left, normal on the right) - no pathological changes consistent with atrophy detected in the ventral dc - the amygdala shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the hippocampus - no pathological changes consistent with atrophy detected in the thalamus - no degenerative or atrophic changes noted in the pallidum - basal forebrain remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the caudate - normal-to-mild bilateral accumbens atrophy For the cerebral cortex: - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: supramarginal gyrus (normal-to-mild atrophy on the left) and postcentral gyrus (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the temporal lobe - no pathological changes consistent with atrophy detected in the frontal lobe - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy both left/right) and posterior insula (normal-to-mild atrophy on the left) - occipital lobe maintains its normal morphology without atrophic features - limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the right), posterior cingulate gyrus (normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left) For the ventricles: - lateral ventricle remains within normal size parameters, with no enlargement detected - no signs of enlargement detected in the 3rd ventricle - no enlargement observed in the inf. lateral ventricle - the external csf shows no structural abnormalities indicative of enlargement - no enlargement observed in the 4th ventricle
CN
We have the following subject's personal information: - The subject is a female of 32.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203142083_03384_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450647
On a T1-weighted brain MRI we observed: For the ventricles: - no enlargement observed in the 3rd ventricle - no enlargement observed in the lateral ventricle - no abnormal enlargement observed in the external csf - inf. lateral ventricle enlargement (moderate on the left, normal on the right) - 4th ventricle is free from enlargement or excessive growth For the subcortical structures: - ventral dc maintains its normal morphology without atrophic features - the pallidum shows no structural abnormalities indicative of atrophy - amygdala atrophy (mild on the left, normal on the right) - no degenerative or atrophic changes noted in the thalamus - normal-to-mild bilateral hippocampus atrophy - caudate maintains its normal morphology without atrophic features - no observable atrophic alterations in the basal forebrain - accumbens presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the putamen For the cerebral cortex: - no evidence of atrophy or degeneration in the occipital lobe - frontal lobe presents with a healthy appearance, free from atrophy - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the parietal lobe - temporal lobe atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (normal-to-mild atrophy on the left) and middle temporal gyrus (normal-to-mild atrophy on the left) - insular cortex appears structurally intact with no atrophic changes
SD
We have the following subject's personal information: - The subject is a male of 61.0 years old. - He has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203989517_02718_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178092
On a T1-weighted brain MRI we observed: For the cerebral cortex: - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the right) - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left), planum polare (normal-to-mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the right) - occipital lobe remains normal, with no signs of tissue loss - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left), postcentral gyrus (normal-to-mild atrophy on the right) and supramarginal gyrus (normal-to-mild atrophy on the left) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), central operculum (normal-to-mild atrophy on the left) and posterior insula (normal-to-mild atrophy on the left) - the frontal lobe shows no structural abnormalities indicative of atrophy For the subcortical structures: - hippocampus atrophy (normal on the left, normal-to-mild on the right) - no degenerative or atrophic changes noted in the basal forebrain - caudate remains normal, with no signs of tissue loss - no observable atrophic alterations in the accumbens - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral putamen atrophy - normal-to-mild bilateral thalamus atrophy - normal-to-mild bilateral amygdala atrophy - normal-to-mild bilateral ventral dc atrophy For the ventricles: - 3rd ventricle maintains its normal volume without signs of enlargement - no signs of enlargement detected in the 4th ventricle - normal-to-mild enlargement of the external csf - inf. lateral ventricle is free from enlargement or excessive growth - lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
CN
We have the following subject's personal information: - The subject is a male of 61.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203963723_01326_MR_Sagittal_MP-Rage_br_raw_20230206172100739_I10182036
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no observable atrophic alterations in the occipital lobe - temporal lobe remains normal, with no signs of tissue loss - no observable atrophic alterations in the limbic cortex - parietal lobe maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the insular cortex - the frontal lobe shows no structural abnormalities indicative of atrophy For the ventricles: - 3rd ventricle maintains its normal volume without signs of enlargement - no enlargement observed in the 4th ventricle - no pathological changes consistent with enlargement noted in the external csf - no observable enlargement or abnormal growth in the lateral ventricle - no signs of enlargement detected in the inf. lateral ventricle For the subcortical structures: - hippocampus maintains its normal morphology without atrophic features - normal-to-mild bilateral accumbens atrophy - no degenerative or atrophic changes noted in the ventral dc - pallidum atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral putamen atrophy - amygdala presents with a healthy appearance, free from atrophy - basal forebrain presents with a healthy appearance, free from atrophy - thalamus appears structurally intact with no atrophic changes - normal-to-mild bilateral caudate atrophy
CN
We have the following subject's personal information: - The subject is a male of 47.0 years old. - He has 17.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203735377_03773_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451145
On a T1-weighted brain MRI we observed: For the cerebral cortex: - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left), frontal operculum (normal-to-mild atrophy on the right), posterior insula (normal-to-mild atrophy on the left) and central operculum (normal-to-mild atrophy on the left) - the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parahippocampal gyrus (mild atrophy on the left), entorhinal area (normal-to-mild atrophy both left/right) and anterior cingulate gyrus (normal-to-mild atrophy on the right) - frontal lobe appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the parietal lobe - temporal lobe atrophy (moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy both left/right), transverse temporal gyrus (normal-to-mild atrophy on the left) and planum temporale (normal-to-mild atrophy on the right) - no pathological changes consistent with atrophy detected in the occipital lobe For the subcortical structures: - caudate atrophy (normal-to-mild on the left, normal on the right) - no signs of atrophy detected in the ventral dc - pallidum atrophy (normal-to-mild on the left, normal on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - putamen atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the basal forebrain - hippocampus atrophy (mild on the left, normal-to-mild on the right) - amygdala atrophy (moderate on the left, normal-to-mild on the right) - accumbens atrophy (mild on the left, normal-to-mild on the right) For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - the 3rd ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild bilateral lateral ventricle enlargement - inf. lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild enlargement of the external csf
SD
We have the following subject's personal information: - The subject is a female of 75.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203547605_02504_MR_Sagittal_MP-Rage_br_raw_20230124213229853_I10178677
On a T1-weighted brain MRI we observed: For the cerebral cortex: - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left), gyrus rectus (normal-to-mild atrophy on the left), frontal pole (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left) and anterior orbital gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy both left/right), postcentral gyrus medial segment (normal-to-mild atrophy on the left), angular gyrus (normal-to-mild atrophy on the left) and postcentral gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy on the right), cuneus (normal-to-mild atrophy on the left) and middle occipital gyrus (normal-to-mild atrophy on the left) - limbic cortex presents with a healthy appearance, free from atrophy - insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), parietal operculum (normal-to-mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the right) For the ventricles: - the lateral ventricle shows no structural abnormalities indicative of enlargement - mild enlargement of the external csf - mild enlargement of the 4th ventricle - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - normal-to-mild enlargement of the 3rd ventricle For the subcortical structures: - caudate maintains its normal morphology without atrophic features - no observable atrophic alterations in the thalamus - amygdala maintains its normal morphology without atrophic features - basal forebrain appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the pallidum - putamen appears structurally intact with no atrophic changes - ventral dc presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the hippocampus - normal-to-mild bilateral accumbens atrophy
CN
We have the following subject's personal information: - The subject is a male of 35.0 years old. - He has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203400491_03190_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450341
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc atrophy (normal on the left, normal-to-mild on the right) - putamen atrophy (normal-to-mild on the left, mild on the right) - pallidum atrophy (normal-to-mild on the left, mild on the right) - no observable atrophic alterations in the hippocampus - amygdala appears structurally intact with no atrophic changes - basal forebrain presents with a healthy appearance, free from atrophy - caudate atrophy (normal-to-mild on the left, mild on the right) - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral thalamus atrophy For the ventricles: - normal-to-mild bilateral inf. lateral ventricle enlargement - normal-to-mild enlargement of the 3rd ventricle - lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - normal-to-mild enlargement of the 4th ventricle - the external csf shows no structural abnormalities indicative of enlargement For the cerebral cortex: - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: medial frontal cortex (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) - limbic cortex maintains its normal morphology without atrophic features - no evidence of atrophy or degeneration in the temporal lobe - no observable atrophic alterations in the parietal lobe - no observable atrophic alterations in the occipital lobe - no pathological changes consistent with atrophy detected in the insular cortex
bvFTD
We have the following subject's personal information: - The subject is a male of 66.0 years old. - He has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203960894_01496_MR_Sagittal_MP-Rage_br_raw_20230206142736819_I10181192
On a T1-weighted brain MRI we observed: For the ventricles: - no enlargement observed in the inf. lateral ventricle - 4th ventricle remains within normal size parameters, with no enlargement detected - 3rd ventricle appears structurally intact, with no evidence of enlargement - no enlargement observed in the lateral ventricle - normal-to-mild enlargement of the external csf For the cerebral cortex: - no degenerative or atrophic changes noted in the insular cortex - no pathological changes consistent with atrophy detected in the occipital lobe - temporal lobe presents with a healthy appearance, free from atrophy - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), sup. parietal lobule (normal-to-mild atrophy both left/right), supramarginal gyrus (normal-to-mild atrophy both left/right) and postcentral gyrus (normal-to-mild atrophy on the left) - limbic cortex appears structurally intact with no atrophic changes - no observable atrophic alterations in the frontal lobe For the subcortical structures: - the caudate shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the pallidum - no degenerative or atrophic changes noted in the ventral dc - accumbens atrophy (normal on the left, normal-to-mild on the right) - amygdala presents with a healthy appearance, free from atrophy - hippocampus maintains its normal morphology without atrophic features - basal forebrain remains normal, with no signs of tissue loss - putamen remains normal, with no signs of tissue loss - thalamus appears structurally intact with no atrophic changes
CN
We have the following subject's personal information: - The subject is a male of 37.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203073267_01767_MR_Sagittal_MP-Rage_br_raw_20230206174654538_I10182229
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), postcentral gyrus (normal-to-mild atrophy on the left) and precuneus (normal-to-mild atrophy on the right) - no pathological changes consistent with atrophy detected in the insular cortex - frontal lobe presents with a healthy appearance, free from atrophy - occipital lobe remains normal, with no signs of tissue loss - the limbic cortex shows no structural abnormalities indicative of atrophy - temporal lobe remains normal, with no signs of tissue loss For the ventricles: - 3rd ventricle maintains its normal volume without signs of enlargement - inf. lateral ventricle is free from enlargement or excessive growth - 4th ventricle maintains its normal volume without signs of enlargement - no pathological changes consistent with enlargement noted in the external csf - no abnormal enlargement observed in the lateral ventricle For the subcortical structures: - no pathological changes consistent with atrophy detected in the hippocampus - normal-to-mild bilateral thalamus atrophy - no degenerative or atrophic changes noted in the basal forebrain - no pathological changes consistent with atrophy detected in the pallidum - no pathological changes consistent with atrophy detected in the amygdala - no pathological changes consistent with atrophy detected in the ventral dc - putamen remains normal, with no signs of tissue loss - normal-to-mild bilateral caudate atrophy - the accumbens shows no structural abnormalities indicative of atrophy
CN
We have the following subject's personal information: - The subject is a male of 60.0 years old. - He has 13.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203035046_03643_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451015
On a T1-weighted brain MRI we observed: For the subcortical structures: - no signs of atrophy detected in the ventral dc - thalamus remains normal, with no signs of tissue loss - no observable atrophic alterations in the pallidum - amygdala presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the basal forebrain - accumbens maintains its normal morphology without atrophic features - normal-to-mild bilateral putamen atrophy - no pathological changes consistent with atrophy detected in the hippocampus - the caudate shows no structural abnormalities indicative of atrophy For the ventricles: - external csf is free from enlargement or excessive growth - inf. lateral ventricle maintains its normal volume without signs of enlargement - the 4th ventricle shows no structural abnormalities indicative of enlargement - no signs of enlargement detected in the lateral ventricle - normal-to-mild enlargement of the 3rd ventricle For the cerebral cortex: - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), calcarine cortex (normal-to-mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy on the left) and occipital pole (normal-to-mild atrophy on the left) - temporal lobe appears structurally intact with no atrophic changes - no observable atrophic alterations in the frontal lobe - no evidence of atrophy or degeneration in the parietal lobe - no pathological changes consistent with atrophy detected in the insular cortex - limbic cortex remains normal, with no signs of tissue loss
CN
We have the following subject's personal information: - The subject is a male of 50.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203265046_03646_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451017
On a T1-weighted brain MRI we observed: For the ventricles: - lateral ventricle maintains its normal volume without signs of enlargement - no observable enlargement or abnormal growth in the 3rd ventricle - no observable enlargement or abnormal growth in the inf. lateral ventricle - no enlargement observed in the 4th ventricle - external csf appears structurally intact, with no evidence of enlargement For the subcortical structures: - no degenerative or atrophic changes noted in the basal forebrain - accumbens atrophy (normal-to-mild on the left, normal on the right) - no signs of atrophy detected in the putamen - thalamus remains normal, with no signs of tissue loss - normal-to-mild bilateral ventral dc atrophy - no degenerative or atrophic changes noted in the pallidum - caudate appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the amygdala - no pathological changes consistent with atrophy detected in the hippocampus For the cerebral cortex: - the parietal lobe shows no structural abnormalities indicative of atrophy - limbic cortex remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the occipital lobe - no degenerative or atrophic changes noted in the insular cortex - no degenerative or atrophic changes noted in the frontal lobe - the temporal lobe shows no structural abnormalities indicative of atrophy
CN
We have the following subject's personal information: - The subject is a female of 34.0 years old. - She has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203244547_01744_MR_Sagittal_MP-Rage_br_raw_20230124205159364_I10178413
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc remains normal, with no signs of tissue loss - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the caudate - thalamus remains normal, with no signs of tissue loss - putamen maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the pallidum - hippocampus atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral amygdala atrophy - accumbens maintains its normal morphology without atrophic features For the ventricles: - no observable enlargement or abnormal growth in the 3rd ventricle - no abnormal enlargement observed in the inf. lateral ventricle - no pathological changes consistent with enlargement noted in the lateral ventricle - no signs of enlargement detected in the 4th ventricle - external csf is free from enlargement or excessive growth For the cerebral cortex: - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the right), temporal pole (normal-to-mild atrophy on the right) and fusiform gyrus (normal-to-mild atrophy on the right) - parietal lobe remains normal, with no signs of tissue loss - limbic cortex appears structurally intact with no atrophic changes - frontal lobe presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the occipital lobe - insular cortex appears structurally intact with no atrophic changes
CN
We have the following subject's personal information: - The subject is a female of 59.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203767795_03596_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450963
On a T1-weighted brain MRI we observed: For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - moderate bilateral inf. lateral ventricle enlargement - mild enlargement of the external csf - lateral ventricle enlargement (normal-to-mild on the left, mild on the right) - no enlargement observed in the 4th ventricle For the cerebral cortex: - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), central operculum (normal-to-mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the left) and posterior insula (normal-to-mild atrophy on the left) - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the left) - occipital lobe maintains its normal morphology without atrophic features - mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right), precuneus (normal-to-mild atrophy both left/right), postcentral gyrus (normal-to-mild atrophy both left/right), supramarginal gyrus (normal-to-mild atrophy on the left) and sup. parietal lobule (normal-to-mild atrophy on the left) - mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left/right), anterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), frontal pole (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the right) and triangular inf. frontal gyrus (normal-to-mild atrophy on the right) - mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy both left/right) and sup. temporal gyrus (normal-to-mild atrophy on the right) For the subcortical structures: - no signs of atrophy detected in the thalamus - mild bilateral putamen atrophy - no degenerative or atrophic changes noted in the pallidum - normal-to-mild bilateral amygdala atrophy - hippocampus atrophy (normal on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the basal forebrain - mild bilateral accumbens atrophy - ventral dc appears structurally intact with no atrophic changes - mild bilateral caudate atrophy
SD
We have the following subject's personal information: - The subject is a female of 65.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 9.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203012630_03031_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177908
On a T1-weighted brain MRI we observed: For the cerebral cortex: - occipital lobe presents with a healthy appearance, free from atrophy - frontal lobe presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the parietal lobe - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy on the right) and inf. temporal gyrus (normal-to-mild atrophy on the right) - no signs of atrophy detected in the limbic cortex - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left) For the ventricles: - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - external csf appears structurally intact, with no evidence of enlargement - lateral ventricle appears structurally intact, with no evidence of enlargement - no observable enlargement or abnormal growth in the 3rd ventricle - no pathological changes consistent with enlargement noted in the 4th ventricle For the subcortical structures: - caudate atrophy (normal on the left, normal-to-mild on the right) - putamen maintains its normal morphology without atrophic features - no signs of atrophy detected in the accumbens - hippocampus remains normal, with no signs of tissue loss - ventral dc presents with a healthy appearance, free from atrophy - the amygdala shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the thalamus - no degenerative or atrophic changes noted in the pallidum - no signs of atrophy detected in the basal forebrain
CN
We have the following subject's personal information: - The subject is a male of 44.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203884715_02518_MR_Sagittal_MP-Rage_br_raw_20230206161048123_I10181559
On a T1-weighted brain MRI we observed: For the ventricles: - inf. lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild bilateral lateral ventricle enlargement - 4th ventricle is free from enlargement or excessive growth - normal-to-mild enlargement of the external csf - 3rd ventricle maintains its normal volume without signs of enlargement For the cerebral cortex: - insular cortex maintains its normal morphology without atrophic features - temporal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. temporal gyrus (normal-to-mild atrophy both left/right), middle temporal gyrus (mild atrophy on the left), temporal pole (normal-to-mild atrophy both left/right), transverse temporal gyrus (mild atrophy on the right), planum temporale (normal-to-mild atrophy on the right) and inf. temporal gyrus (normal-to-mild atrophy on the left) - parietal lobe appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the occipital lobe - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) and medial orbital gyrus (normal-to-mild atrophy on the left) For the subcortical structures: - normal-to-mild bilateral putamen atrophy - basal forebrain remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the hippocampus - ventral dc appears structurally intact with no atrophic changes - normal-to-mild bilateral accumbens atrophy - caudate atrophy (mild on the left, normal-to-mild on the right) - amygdala atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the thalamus - pallidum atrophy (normal-to-mild on the left, normal on the right)
bvFTD
We have the following subject's personal information: - The subject is a male of 69.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203661911_02116_MR_Sagittal_MP-Rage_br_raw_20230206154039408_I10181429
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no signs of atrophy detected in the parietal lobe - temporal lobe atrophy (moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild atrophy on the left), planum polare (normal-to-mild atrophy both left/right), inf. temporal gyrus (normal-to-mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy both left/right) and planum temporale (normal-to-mild atrophy on the left) - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: lateral orbital gyrus (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left) and medial frontal cortex (normal-to-mild atrophy on the left) - limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - no pathological changes consistent with atrophy detected in the occipital lobe - insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), frontal operculum (normal-to-mild atrophy both left/right), posterior insula (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left) For the subcortical structures: - amygdala atrophy (moderate on the left, mild on the right) - thalamus atrophy (mild on the left, normal on the right) - caudate atrophy (mild on the left, normal on the right) - pallidum atrophy (normal-to-mild on the left, normal on the right) - the basal forebrain shows no structural abnormalities indicative of atrophy - putamen atrophy (mild on the left, normal-to-mild on the right) - hippocampus atrophy (mild on the left, normal-to-mild on the right) - no signs of atrophy detected in the ventral dc - accumbens atrophy (moderate on the left, normal-to-mild on the right) For the ventricles: - inf. lateral ventricle enlargement (moderate on the left, mild on the right) - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - mild enlargement of the external csf - no signs of enlargement detected in the 4th ventricle - normal-to-mild enlargement of the 3rd ventricle
SD
We have the following subject's personal information: - The subject is a male of 73.0 years old. - He has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203340631_03134_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177156
On a T1-weighted brain MRI we observed: For the cerebral cortex: - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), posterior insula (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left) - no pathological changes consistent with atrophy detected in the frontal lobe - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), postcentral gyrus (normal-to-mild atrophy on the right) and sup. parietal lobule (normal-to-mild atrophy on the left) - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy both left/right) and posterior cingulate gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left) and planum temporale (normal-to-mild atrophy on the left) - occipital lobe presents with a healthy appearance, free from atrophy For the subcortical structures: - normal-to-mild bilateral caudate atrophy - amygdala atrophy (mild on the left, moderate on the right) - accumbens atrophy (normal-to-mild on the left, mild on the right) - normal-to-mild bilateral thalamus atrophy - no observable atrophic alterations in the basal forebrain - the ventral dc shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral putamen atrophy - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral hippocampus atrophy For the ventricles: - the lateral ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the 3rd ventricle - 4th ventricle maintains its normal volume without signs of enlargement - inf. lateral ventricle enlargement (normal-to-mild on the left, mild on the right) - mild enlargement of the external csf
bvFTD
We have the following subject's personal information: - The subject is a male of 65.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on behavior, comportment, and personality, corresponding to moderate impairment.
FTLD_203957000_01005_MR_Sagittal_MP-Rage_br_raw_20230206132836995_I10181012
On a T1-weighted brain MRI we observed: For the subcortical structures: - amygdala appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the ventral dc - basal forebrain remains normal, with no signs of tissue loss - caudate maintains its normal morphology without atrophic features - the hippocampus shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the putamen - no evidence of atrophy or degeneration in the thalamus - normal-to-mild bilateral accumbens atrophy - no degenerative or atrophic changes noted in the pallidum For the cerebral cortex: - limbic cortex presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the insular cortex - the parietal lobe shows no structural abnormalities indicative of atrophy - temporal lobe maintains its normal morphology without atrophic features - occipital lobe appears structurally intact with no atrophic changes - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the left), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the left) and precentral gyrus (normal-to-mild atrophy on the right) For the ventricles: - lateral ventricle maintains its normal volume without signs of enlargement - no observable enlargement or abnormal growth in the 4th ventricle - 3rd ventricle is free from enlargement or excessive growth - no pathological changes consistent with enlargement noted in the external csf - no observable enlargement or abnormal growth in the inf. lateral ventricle
CN
We have the following subject's personal information: - The subject is a male of 60.0 years old. - He has 19.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203746600_01004_MR_Sagittal_MP-Rage_br_raw_20230206132803138_I10181011
On a T1-weighted brain MRI we observed: For the subcortical structures: - hippocampus remains normal, with no signs of tissue loss - mild bilateral caudate atrophy - accumbens atrophy (normal-to-mild on the left, mild on the right) - no evidence of atrophy or degeneration in the amygdala - the ventral dc shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral putamen atrophy - thalamus atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral pallidum atrophy - basal forebrain maintains its normal morphology without atrophic features For the ventricles: - no enlargement observed in the lateral ventricle - normal-to-mild enlargement of the external csf - no abnormal enlargement observed in the 3rd ventricle - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - no observable enlargement or abnormal growth in the 4th ventricle For the cerebral cortex: - limbic cortex appears structurally intact with no atrophic changes - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: supramarginal gyrus (normal-to-mild atrophy both left/right) and postcentral gyrus medial segment (normal-to-mild atrophy on the left) - the frontal lobe shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the occipital lobe - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: parietal operculum (normal-to-mild atrophy both left/right) and posterior insula (normal-to-mild atrophy on the left) - no signs of atrophy detected in the temporal lobe
CN
We have the following subject's personal information: - The subject is a male of 36.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203337893_03393_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450664
On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the external csf - no enlargement observed in the 4th ventricle - lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral inf. lateral ventricle enlargement - normal-to-mild enlargement of the 3rd ventricle For the subcortical structures: - no degenerative or atrophic changes noted in the basal forebrain - no evidence of atrophy or degeneration in the amygdala - normal-to-mild bilateral accumbens atrophy - putamen appears structurally intact with no atrophic changes - normal-to-mild bilateral ventral dc atrophy - mild bilateral pallidum atrophy - thalamus atrophy (normal-to-mild on the left, normal on the right) - the hippocampus shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the caudate For the cerebral cortex: - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the left), anterior cingulate gyrus (normal-to-mild atrophy on the right), entorhinal area (normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the right) - occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: occipital pole (normal-to-mild atrophy both left/right), cuneus (normal-to-mild atrophy on the right) and middle occipital gyrus (normal-to-mild atrophy on the left) - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: central operculum (mild atrophy on the left), anterior insula (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy on the right) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), precentral gyrus (mild atrophy on the left), gyrus rectus (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy on the left) and posterior orbital gyrus (normal-to-mild atrophy on the left) - temporal lobe remains normal, with no signs of tissue loss - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: supramarginal gyrus (normal-to-mild atrophy on the right), angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy both left/right) and postcentral gyrus (normal-to-mild atrophy on the left)
bvFTD
We have the following subject's personal information: - The subject is a male of 58.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 8.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203317150_03051_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177392
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no degenerative or atrophic changes noted in the parietal lobe - mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left/right), precentral gyrus (mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) - no evidence of atrophy or degeneration in the temporal lobe - the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and anterior cingulate gyrus (normal-to-mild atrophy on the left) - no evidence of atrophy or degeneration in the occipital lobe - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: frontal operculum (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy on the left) For the subcortical structures: - caudate atrophy (normal-to-mild on the left, normal on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - basal forebrain maintains its normal morphology without atrophic features - the ventral dc shows no structural abnormalities indicative of atrophy - pallidum atrophy (normal-to-mild on the left, normal on the right) - hippocampus atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral putamen atrophy - amygdala maintains its normal morphology without atrophic features For the ventricles: - normal-to-mild enlargement of the external csf - no observable enlargement or abnormal growth in the 4th ventricle - no abnormal enlargement observed in the inf. lateral ventricle - normal-to-mild bilateral lateral ventricle enlargement - normal-to-mild enlargement of the 3rd ventricle
PNFA
We have the following subject's personal information: - The subject is a male of 61.0 years old. - He has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203261907_03706_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451087
On a T1-weighted brain MRI we observed: For the subcortical structures: - normal-to-mild bilateral hippocampus atrophy - normal-to-mild bilateral caudate atrophy - basal forebrain appears structurally intact with no atrophic changes - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral ventral dc atrophy - normal-to-mild bilateral thalamus atrophy - normal-to-mild bilateral putamen atrophy - amygdala atrophy (normal-to-mild on the left, normal on the right) For the ventricles: - inf. lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - external csf maintains its normal volume without signs of enlargement - normal-to-mild enlargement of the 3rd ventricle - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild enlargement of the 4th ventricle For the cerebral cortex: - no pathological changes consistent with atrophy detected in the occipital lobe - no pathological changes consistent with atrophy detected in the limbic cortex - frontal lobe appears structurally intact with no atrophic changes - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy both left/right) and sup. temporal gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the parietal lobe - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy both left/right), parietal operculum (normal-to-mild atrophy on the left), posterior insula (normal-to-mild atrophy on the left) and frontal operculum (normal-to-mild atrophy on the right)
bvFTD
We have the following subject's personal information: - The subject is a male of 69.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on behavior, comportment, and personality, corresponding to moderate impairment.
FTLD_203150865_03565_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450934
On a T1-weighted brain MRI we observed: For the ventricles: - no abnormal enlargement observed in the 4th ventricle - the external csf shows no structural abnormalities indicative of enlargement - normal-to-mild bilateral lateral ventricle enlargement - inf. lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - mild enlargement of the 3rd ventricle For the subcortical structures: - no observable atrophic alterations in the amygdala - accumbens atrophy (mild on the left, normal-to-mild on the right) - no evidence of atrophy or degeneration in the basal forebrain - ventral dc remains normal, with no signs of tissue loss - putamen atrophy (mild on the left, normal-to-mild on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - caudate atrophy (normal-to-mild on the left, normal on the right) - no evidence of atrophy or degeneration in the hippocampus - normal-to-mild bilateral pallidum atrophy For the cerebral cortex: - temporal lobe remains normal, with no signs of tissue loss - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: precentral gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the right) and orbital inf. frontal gyrus (normal-to-mild atrophy on the right) - insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), posterior insula (normal-to-mild atrophy both left/right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and parietal operculum (normal-to-mild atrophy both left/right) - no observable atrophic alterations in the occipital lobe - no pathological changes consistent with atrophy detected in the limbic cortex - parietal lobe presents with a healthy appearance, free from atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left), postcentral gyrus (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the left)
PNFA
We have the following subject's personal information: - The subject is a female of 68.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203632540_01043_MR_Sagittal_MP-Rage_br_raw_20230124214115136_I10178739
On a T1-weighted brain MRI we observed: For the subcortical structures: - pallidum maintains its normal morphology without atrophic features - no observable atrophic alterations in the hippocampus - no observable atrophic alterations in the thalamus - caudate remains normal, with no signs of tissue loss - amygdala appears structurally intact with no atrophic changes - accumbens atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral putamen atrophy - normal-to-mild bilateral ventral dc atrophy - no pathological changes consistent with atrophy detected in the basal forebrain For the cerebral cortex: - no degenerative or atrophic changes noted in the insular cortex - no pathological changes consistent with atrophy detected in the parietal lobe - frontal lobe presents with a healthy appearance, free from atrophy - the occipital lobe shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the temporal lobe - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy both left/right) and anterior cingulate gyrus (normal-to-mild atrophy on the right) For the ventricles: - normal-to-mild enlargement of the 4th ventricle - no abnormal enlargement observed in the external csf - lateral ventricle remains within normal size parameters, with no enlargement detected - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the 3rd ventricle
CN
We have the following subject's personal information: - The subject is a male of 44.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203400680_02080_MR_Sagittal_MP-Rage_br_raw_20230209094954957_I10183282
On a T1-weighted brain MRI we observed: For the ventricles: - normal-to-mild enlargement of the external csf - the lateral ventricle shows no structural abnormalities indicative of enlargement - 4th ventricle remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the inf. lateral ventricle - no signs of enlargement detected in the 3rd ventricle For the subcortical structures: - the amygdala shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral caudate atrophy - the basal forebrain shows no structural abnormalities indicative of atrophy - hippocampus appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the accumbens - no signs of atrophy detected in the pallidum - no degenerative or atrophic changes noted in the putamen - no degenerative or atrophic changes noted in the ventral dc - thalamus presents with a healthy appearance, free from atrophy For the cerebral cortex: - normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: middle occipital gyrus (mild atrophy on the right), cuneus (normal-to-mild atrophy on the left), occipital fusiform gyrus (normal-to-mild atrophy on the left), lingual gyrus (normal-to-mild atrophy on the right) and inf. occipital gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the limbic cortex - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy on the left), postcentral gyrus medial segment (normal-to-mild atrophy both left/right) and angular gyrus (normal-to-mild atrophy on the right) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: frontal operculum (normal-to-mild atrophy both left/right), central operculum (normal-to-mild atrophy on the left) and anterior insula (normal-to-mild atrophy on the left) - no observable atrophic alterations in the frontal lobe - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the right)
CN
We have the following subject's personal information: - The subject is a male of 29.0 years old. - He has 13.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203095264_01469_MR_Sagittal_MP-Rage_br_raw_20230124205045939_I10178402
On a T1-weighted brain MRI we observed: For the subcortical structures: - no degenerative or atrophic changes noted in the amygdala - normal-to-mild bilateral putamen atrophy - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral thalamus atrophy - no observable atrophic alterations in the basal forebrain - no pathological changes consistent with atrophy detected in the hippocampus - caudate presents with a healthy appearance, free from atrophy - normal-to-mild bilateral ventral dc atrophy - normal-to-mild bilateral accumbens atrophy For the cerebral cortex: - no evidence of atrophy or degeneration in the temporal lobe - no evidence of atrophy or degeneration in the frontal lobe - parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the right), postcentral gyrus (normal-to-mild atrophy on the left) and sup. parietal lobule (normal-to-mild atrophy on the right) - no observable atrophic alterations in the limbic cortex - no signs of atrophy detected in the occipital lobe - insular cortex maintains its normal morphology without atrophic features For the ventricles: - 4th ventricle is free from enlargement or excessive growth - external csf maintains its normal volume without signs of enlargement - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - no abnormal enlargement observed in the 3rd ventricle - normal-to-mild bilateral lateral ventricle enlargement
CN
We have the following subject's personal information: - The subject is a female of 58.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203556698_01895_MR_Sagittal_MP-Rage_br_raw_20230209093738415_I10183224
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle appears structurally intact, with no evidence of enlargement - no enlargement observed in the external csf - no pathological changes consistent with enlargement noted in the 3rd ventricle - the lateral ventricle shows no structural abnormalities indicative of enlargement - no observable enlargement or abnormal growth in the inf. lateral ventricle For the cerebral cortex: - insular cortex presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the parietal lobe - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (mild atrophy on the right), subcallosal area (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left) and supplementary motor cortex (normal-to-mild atrophy on the right) - temporal lobe presents with a healthy appearance, free from atrophy - normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: lingual gyrus (normal-to-mild atrophy on the left), middle occipital gyrus (normal-to-mild atrophy on the left) and calcarine cortex (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy both left/right) and anterior cingulate gyrus (normal-to-mild atrophy on the right) For the subcortical structures: - no evidence of atrophy or degeneration in the caudate - no evidence of atrophy or degeneration in the accumbens - no degenerative or atrophic changes noted in the basal forebrain - the hippocampus shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the putamen - no signs of atrophy detected in the amygdala - no degenerative or atrophic changes noted in the ventral dc - thalamus presents with a healthy appearance, free from atrophy - pallidum presents with a healthy appearance, free from atrophy
CN
We have the following subject's personal information: - The subject is a female of 49.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203540027_02724_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177236
On a T1-weighted brain MRI we observed: For the subcortical structures: - amygdala atrophy (moderate on the left, mild on the right) - putamen atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral caudate atrophy - hippocampus atrophy (mild on the left, normal-to-mild on the right) - no evidence of atrophy or degeneration in the basal forebrain - no evidence of atrophy or degeneration in the thalamus - pallidum atrophy (normal-to-mild on the left, normal on the right) - accumbens atrophy (mild on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the ventral dc For the ventricles: - mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (severe on the left, moderate on the right) - normal-to-mild enlargement of the 4th ventricle - normal-to-mild enlargement of the external csf - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) For the cerebral cortex: - no signs of atrophy detected in the occipital lobe - no degenerative or atrophic changes noted in the parietal lobe - no degenerative or atrophic changes noted in the frontal lobe - temporal lobe atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and anterior cingulate gyrus (normal-to-mild atrophy on the right) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left)
SD
We have the following subject's personal information: - The subject is a male of 53.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203308097_03790_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451150
On a T1-weighted brain MRI we observed: For the subcortical structures: - pallidum appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the thalamus - hippocampus presents with a healthy appearance, free from atrophy - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - accumbens maintains its normal morphology without atrophic features - no signs of atrophy detected in the ventral dc - normal-to-mild bilateral caudate atrophy - no pathological changes consistent with atrophy detected in the amygdala - normal-to-mild bilateral putamen atrophy For the cerebral cortex: - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle occipital gyrus (normal-to-mild atrophy both left/right), lingual gyrus (normal-to-mild atrophy on the left), inf. occipital gyrus (normal-to-mild atrophy on the right), sup. occipital gyrus (normal-to-mild atrophy on the right) and calcarine cortex (normal-to-mild atrophy on the right) - insular cortex presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the frontal lobe - no signs of atrophy detected in the limbic cortex - no observable atrophic alterations in the parietal lobe - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the left), fusiform gyrus (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the right) For the ventricles: - no signs of enlargement detected in the lateral ventricle - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - normal-to-mild enlargement of the external csf - 3rd ventricle is free from enlargement or excessive growth - 4th ventricle is free from enlargement or excessive growth
CN
We have the following subject's personal information: - The subject is a female of 59.0 years old. - She has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203021096_03692_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10451067
On a T1-weighted brain MRI we observed: For the cerebral cortex: - the temporal lobe shows no structural abnormalities indicative of atrophy - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left), posterior cingulate gyrus (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) - the occipital lobe shows no structural abnormalities indicative of atrophy - parietal lobe appears structurally intact with no atrophic changes - insular cortex appears structurally intact with no atrophic changes - frontal lobe presents with a healthy appearance, free from atrophy For the subcortical structures: - normal-to-mild bilateral amygdala atrophy - no degenerative or atrophic changes noted in the hippocampus - normal-to-mild bilateral accumbens atrophy - no degenerative or atrophic changes noted in the basal forebrain - normal-to-mild bilateral pallidum atrophy - no degenerative or atrophic changes noted in the caudate - putamen atrophy (mild on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the thalamus - no signs of atrophy detected in the ventral dc For the ventricles: - 4th ventricle remains within normal size parameters, with no enlargement detected - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - external csf is free from enlargement or excessive growth - inf. lateral ventricle maintains its normal volume without signs of enlargement - no observable enlargement or abnormal growth in the 3rd ventricle
SD
We have the following subject's personal information: - The subject is a male of 79.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on behavior, comportment, and personality, corresponding to no impairment.
FTLD_203813234_02431_MR_Sagittal_MP-Rage_br_raw_20230209101907239_I10183427
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral pallidum atrophy - hippocampus atrophy (normal-to-mild on the left, normal on the right) - accumbens atrophy (moderate on the left, mild on the right) - basal forebrain presents with a healthy appearance, free from atrophy - normal-to-mild bilateral amygdala atrophy - mild bilateral putamen atrophy - ventral dc atrophy (mild on the left, normal-to-mild on the right) - caudate atrophy (mild on the left, normal-to-mild on the right) - thalamus atrophy (moderate on the left, mild on the right) For the cerebral cortex: - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: frontal operculum (normal-to-mild atrophy both left/right), anterior insula (normal-to-mild atrophy both left/right), central operculum (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the right) - no evidence of atrophy or degeneration in the occipital lobe - no signs of atrophy detected in the temporal lobe - parietal lobe appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the frontal lobe For the ventricles: - normal-to-mild enlargement of the external csf - moderate enlargement of the 3rd ventricle - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - inf. lateral ventricle enlargement (moderate on the left, normal-to-mild on the right) - normal-to-mild enlargement of the 4th ventricle
bvFTD
We have the following subject's personal information: - The subject is a male of 55.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203503701_01100_MR_Sagittal_MP-Rage_br_raw_20230206133640819_I10181037
On a T1-weighted brain MRI we observed: For the ventricles: - the external csf shows no structural abnormalities indicative of enlargement - no signs of enlargement detected in the 4th ventricle - lateral ventricle maintains its normal volume without signs of enlargement - no observable enlargement or abnormal growth in the 3rd ventricle - no abnormal enlargement observed in the inf. lateral ventricle For the cerebral cortex: - no degenerative or atrophic changes noted in the limbic cortex - the insular cortex shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the frontal lobe - the temporal lobe shows no structural abnormalities indicative of atrophy - parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. parietal lobule (normal-to-mild atrophy both left/right) and postcentral gyrus medial segment (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the occipital lobe For the subcortical structures: - no degenerative or atrophic changes noted in the caudate - no signs of atrophy detected in the pallidum - no signs of atrophy detected in the putamen - hippocampus appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the accumbens - no signs of atrophy detected in the amygdala - thalamus maintains its normal morphology without atrophic features - the ventral dc shows no structural abnormalities indicative of atrophy - basal forebrain appears structurally intact with no atrophic changes
CN
We have the following subject's personal information: - The subject is a female of 64.0 years old. - She has 17.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203454401_03105_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178120
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy both left/right), supramarginal gyrus (normal-to-mild atrophy on the left), angular gyrus (normal-to-mild atrophy on the left), postcentral gyrus medial segment (normal-to-mild atrophy on the right) and sup. parietal lobule (normal-to-mild atrophy on the left) - frontal lobe appears structurally intact with no atrophic changes - temporal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the right) - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy on the right), parietal operculum (normal-to-mild atrophy on the right) and central operculum (normal-to-mild atrophy on the right) - limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy both left/right), entorhinal area (normal-to-mild atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the right) - no observable atrophic alterations in the occipital lobe For the ventricles: - no enlargement observed in the 4th ventricle - normal-to-mild enlargement of the external csf - normal-to-mild enlargement of the 3rd ventricle - normal-to-mild bilateral lateral ventricle enlargement - inf. lateral ventricle enlargement (mild on the left, moderate on the right) For the subcortical structures: - the ventral dc shows no structural abnormalities indicative of atrophy - accumbens atrophy (normal-to-mild on the left, mild on the right) - putamen atrophy (normal-to-mild on the left, mild on the right) - thalamus appears structurally intact with no atrophic changes - basal forebrain appears structurally intact with no atrophic changes - amygdala atrophy (mild on the left, moderate on the right) - caudate atrophy (normal on the left, normal-to-mild on the right) - hippocampus atrophy (normal-to-mild on the left, mild on the right) - normal-to-mild bilateral pallidum atrophy
bvFTD
We have the following subject's personal information: - The subject is a male of 72.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203521064_02462_MR_Sagittal_MP-Rage_br_raw_20230124213025498_I10178666
On a T1-weighted brain MRI we observed: For the ventricles: - no signs of enlargement detected in the 3rd ventricle - 4th ventricle remains within normal size parameters, with no enlargement detected - lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - inf. lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - external csf maintains its normal volume without signs of enlargement For the cerebral cortex: - frontal lobe appears structurally intact with no atrophic changes - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: sup. temporal gyrus (normal-to-mild atrophy on the left), temporal pole (normal-to-mild atrophy both left/right) and fusiform gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the right) - occipital lobe maintains its normal morphology without atrophic features - insular cortex maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the parietal lobe For the subcortical structures: - normal-to-mild bilateral amygdala atrophy - normal-to-mild bilateral ventral dc atrophy - no observable atrophic alterations in the pallidum - caudate maintains its normal morphology without atrophic features - accumbens maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the putamen - basal forebrain appears structurally intact with no atrophic changes - no observable atrophic alterations in the thalamus - mild bilateral hippocampus atrophy
CN
We have the following subject's personal information: - The subject is a female of 45.0 years old. - She has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203583546_01648_MR_Sagittal_MP-Rage_br_raw_20230206173833327_I10182163
On a T1-weighted brain MRI we observed: For the cerebral cortex: - insular cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and moderate atrophy on the right), frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) and posterior insula (normal-to-mild atrophy both left/right) - limbic cortex atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), parahippocampal gyrus (mild atrophy on the right), entorhinal area (normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the left) - frontal lobe atrophy (normal-to-mild on the left, moderate on the right), with focal volume loss observed in the following subregions: medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the right) and subcallosal area (normal-to-mild atrophy on the right) - no evidence of atrophy or degeneration in the parietal lobe - occipital lobe remains normal, with no signs of tissue loss - temporal lobe atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy on the right), temporal pole (normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the right), planum polare (normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left) For the ventricles: - normal-to-mild bilateral lateral ventricle enlargement - 4th ventricle remains within normal size parameters, with no enlargement detected - normal-to-mild enlargement of the external csf - inf. lateral ventricle enlargement (normal on the left, moderate on the right) - no enlargement observed in the 3rd ventricle For the subcortical structures: - ventral dc presents with a healthy appearance, free from atrophy - the pallidum shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral hippocampus atrophy - amygdala atrophy (normal-to-mild on the left, moderate on the right) - accumbens atrophy (mild on the left, moderate on the right) - no degenerative or atrophic changes noted in the basal forebrain - putamen atrophy (normal-to-mild on the left, mild on the right) - caudate atrophy (mild on the left, moderate on the right) - no pathological changes consistent with atrophy detected in the thalamus
bvFTD
We have the following subject's personal information: - The subject is a male of 62.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203042261_03164_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177288
On a T1-weighted brain MRI we observed: For the subcortical structures: - no signs of atrophy detected in the accumbens - amygdala presents with a healthy appearance, free from atrophy - ventral dc remains normal, with no signs of tissue loss - thalamus atrophy (normal-to-mild on the left, normal on the right) - no signs of atrophy detected in the hippocampus - no signs of atrophy detected in the putamen - no degenerative or atrophic changes noted in the basal forebrain - no signs of atrophy detected in the pallidum - caudate appears structurally intact with no atrophic changes For the cerebral cortex: - occipital lobe presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the insular cortex - no observable atrophic alterations in the parietal lobe - no degenerative or atrophic changes noted in the frontal lobe - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy on the right), planum polare (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the right) and anterior cingulate gyrus (normal-to-mild atrophy both left/right) For the ventricles: - no pathological changes consistent with enlargement noted in the 3rd ventricle - lateral ventricle appears structurally intact, with no evidence of enlargement - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - no abnormal enlargement observed in the external csf - no enlargement observed in the 4th ventricle
CN
We have the following subject's personal information: - The subject is a male of 33.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203985877_03778_MR_Accelerated_Sagittal_MPRAGE_br_raw_20250_I11137580
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle appears structurally intact, with no evidence of enlargement - no signs of enlargement detected in the 4th ventricle - inf. lateral ventricle enlargement (mild on the left, normal on the right) - the lateral ventricle shows no structural abnormalities indicative of enlargement - the external csf shows no structural abnormalities indicative of enlargement For the cerebral cortex: - no pathological changes consistent with atrophy detected in the parietal lobe - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right) and central operculum (normal-to-mild atrophy on the right) - no signs of atrophy detected in the limbic cortex - temporal lobe atrophy (moderate on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left), sup. temporal gyrus (normal-to-mild atrophy both left/right) and transverse temporal gyrus (normal-to-mild atrophy on the right) - the occipital lobe shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the frontal lobe For the subcortical structures: - pallidum presents with a healthy appearance, free from atrophy - hippocampus atrophy (normal-to-mild on the left, normal on the right) - amygdala atrophy (normal-to-mild on the left, normal on the right) - putamen atrophy (normal-to-mild on the left, normal on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - ventral dc appears structurally intact with no atrophic changes - no observable atrophic alterations in the basal forebrain - no signs of atrophy detected in the caudate - accumbens atrophy (normal-to-mild on the left, normal on the right)
SD
We have the following subject's personal information: - The subject is a female of 69.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203588016_01618_MR_Sagittal_MP-Rage_br_raw_20230206183244786_I10182553
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no observable atrophic alterations in the parietal lobe - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the left) and precentral gyrus medial segment (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the occipital lobe - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the right) - no observable atrophic alterations in the insular cortex - no pathological changes consistent with atrophy detected in the temporal lobe For the subcortical structures: - no observable atrophic alterations in the accumbens - the thalamus shows no structural abnormalities indicative of atrophy - the amygdala shows no structural abnormalities indicative of atrophy - basal forebrain remains normal, with no signs of tissue loss - ventral dc presents with a healthy appearance, free from atrophy - hippocampus appears structurally intact with no atrophic changes - putamen maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the caudate - pallidum remains normal, with no signs of tissue loss For the ventricles: - 4th ventricle remains within normal size parameters, with no enlargement detected - 3rd ventricle is free from enlargement or excessive growth - no signs of enlargement detected in the lateral ventricle - normal-to-mild enlargement of the external csf - no pathological changes consistent with enlargement noted in the inf. lateral ventricle
CN
We have the following subject's personal information: - The subject is a female of 44.0 years old. - She has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203139571_01173_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176849
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe maintains its normal morphology without atrophic features - no signs of atrophy detected in the frontal lobe - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy on the left) and posterior cingulate gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left), planum polare (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the left) - no signs of atrophy detected in the occipital lobe - no pathological changes consistent with atrophy detected in the insular cortex For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - lateral ventricle is free from enlargement or excessive growth - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - external csf is free from enlargement or excessive growth - no signs of enlargement detected in the 3rd ventricle For the subcortical structures: - pallidum appears structurally intact with no atrophic changes - ventral dc appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the accumbens - the putamen shows no structural abnormalities indicative of atrophy - caudate presents with a healthy appearance, free from atrophy - the thalamus shows no structural abnormalities indicative of atrophy - basal forebrain presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the hippocampus - amygdala maintains its normal morphology without atrophic features
bvFTD
We have the following subject's personal information: - The subject is a male of 64.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203440685_03584_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450955
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement or abnormal growth in the 4th ventricle - lateral ventricle is free from enlargement or excessive growth - inf. lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - mild enlargement of the external csf - no pathological changes consistent with enlargement noted in the 3rd ventricle For the subcortical structures: - hippocampus remains normal, with no signs of tissue loss - normal-to-mild bilateral caudate atrophy - normal-to-mild bilateral basal forebrain atrophy - normal-to-mild bilateral putamen atrophy - ventral dc atrophy (normal-to-mild on the left, mild on the right) - pallidum atrophy (normal-to-mild on the left, mild on the right) - mild bilateral accumbens atrophy - amygdala atrophy (normal-to-mild on the left, normal on the right) - thalamus atrophy (normal on the left, mild on the right) For the cerebral cortex: - no signs of atrophy detected in the parietal lobe - temporal lobe remains normal, with no signs of tissue loss - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy both left/right) and central operculum (normal-to-mild atrophy on the right) - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy both left/right) - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: occipital pole (normal-to-mild atrophy both left/right), occipital fusiform gyrus (normal-to-mild atrophy on the right) and inf. occipital gyrus (normal-to-mild atrophy on the left) - frontal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: precentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), frontal pole (normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left) and lateral orbital gyrus (normal-to-mild atrophy on the left)
PNFA
We have the following subject's personal information: - The subject is a female of 83.0 years old. - She has 8.0 years of education We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203790540_03049_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176897
On a T1-weighted brain MRI we observed: For the cerebral cortex: - normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: inf. occipital gyrus (normal-to-mild atrophy both left/right) and middle occipital gyrus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the frontal lobe - no degenerative or atrophic changes noted in the parietal lobe - no signs of atrophy detected in the limbic cortex - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy on the left), central operculum (normal-to-mild atrophy on the left), parietal operculum (normal-to-mild atrophy on the left) and anterior insula (normal-to-mild atrophy on the right) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the left) and inf. temporal gyrus (normal-to-mild atrophy on the left) For the ventricles: - no pathological changes consistent with enlargement noted in the 3rd ventricle - no enlargement observed in the lateral ventricle - no signs of enlargement detected in the inf. lateral ventricle - 4th ventricle remains within normal size parameters, with no enlargement detected - external csf remains within normal size parameters, with no enlargement detected For the subcortical structures: - accumbens remains normal, with no signs of tissue loss - the thalamus shows no structural abnormalities indicative of atrophy - the caudate shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the hippocampus - no degenerative or atrophic changes noted in the ventral dc - no evidence of atrophy or degeneration in the putamen - no observable atrophic alterations in the amygdala - no evidence of atrophy or degeneration in the basal forebrain - no observable atrophic alterations in the pallidum
PNFA
We have the following subject's personal information: - The subject is a female of 60.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on behavior, comportment, and personality, corresponding to no impairment.
FTLD_203875531_03137_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450288
On a T1-weighted brain MRI we observed: For the subcortical structures: - pallidum atrophy (mild on the left, normal-to-mild on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - accumbens presents with a healthy appearance, free from atrophy - basal forebrain appears structurally intact with no atrophic changes - putamen atrophy (normal-to-mild on the left, normal on the right) - amygdala atrophy (moderate on the left, normal-to-mild on the right) - caudate appears structurally intact with no atrophic changes - the hippocampus shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral ventral dc atrophy For the ventricles: - lateral ventricle remains within normal size parameters, with no enlargement detected - the 4th ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the 3rd ventricle - external csf maintains its normal volume without signs of enlargement - inf. lateral ventricle enlargement (moderate on the left, normal on the right) For the cerebral cortex: - insular cortex appears structurally intact with no atrophic changes - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (mild atrophy on the right), middle occipital gyrus (normal-to-mild atrophy on the right), inf. occipital gyrus (normal-to-mild atrophy on the left) and occipital pole (normal-to-mild atrophy on the right) - temporal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left), planum polare (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy on the left) and inf. temporal gyrus (normal-to-mild atrophy on the left) - limbic cortex maintains its normal morphology without atrophic features - no signs of atrophy detected in the parietal lobe - no evidence of atrophy or degeneration in the frontal lobe
SD
We have the following subject's personal information: - The subject is a female of 73.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203859441_01145_MR_Sagittal_MP-Rage_br_raw_20230206162408878_I10181623
On a T1-weighted brain MRI we observed: For the subcortical structures: - pallidum remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the hippocampus - no signs of atrophy detected in the putamen - no pathological changes consistent with atrophy detected in the caudate - normal-to-mild bilateral basal forebrain atrophy - normal-to-mild bilateral amygdala atrophy - thalamus appears structurally intact with no atrophic changes - ventral dc remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the accumbens For the ventricles: - the lateral ventricle shows no structural abnormalities indicative of enlargement - no abnormal enlargement observed in the 4th ventricle - no observable enlargement or abnormal growth in the 3rd ventricle - no pathological changes consistent with enlargement noted in the external csf - inf. lateral ventricle maintains its normal volume without signs of enlargement For the cerebral cortex: - no pathological changes consistent with atrophy detected in the temporal lobe - normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), occipital fusiform gyrus (mild atrophy on the right), inf. occipital gyrus (normal-to-mild atrophy both left/right), sup. occipital gyrus (normal-to-mild atrophy on the left) and lingual gyrus (normal-to-mild atrophy on the left) - parietal lobe appears structurally intact with no atrophic changes - limbic cortex remains normal, with no signs of tissue loss - insular cortex remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the frontal lobe
CN
We have the following subject's personal information: - The subject is a female of 56.0 years old. - She has 13.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.