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ALLFTD-wCN-2sigma-1234T-wCS-minSubset-testset-T3RepXMRI-DNT

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subject string	txt_report string	gold_diagnosis string	cognitive_txt string
FTLD_203413336_03631_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10451002	On a T1-weighted brain MRI we observed: For the cerebral cortex: - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (mild atrophy both left/right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy both left/right) and precentral gyrus (normal-to-mild atrophy on the right) - parietal lobe appears structurally intact with no atrophic changes - temporal lobe atrophy (moderate on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), planum polare (mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild atrophy on the left), fusiform gyrus (normal-to-mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the right) and inf. temporal gyrus (normal-to-mild atrophy on the left) - insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy both left/right), anterior insula (mild atrophy on the left) and central operculum (normal-to-mild atrophy on the left) - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left), anterior cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - no signs of atrophy detected in the occipital lobe For the subcortical structures: - hippocampus atrophy (normal-to-mild on the left, normal on the right) - thalamus presents with a healthy appearance, free from atrophy - basal forebrain appears structurally intact with no atrophic changes - no signs of atrophy detected in the caudate - ventral dc appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the pallidum - putamen remains normal, with no signs of tissue loss - accumbens atrophy (mild on the left, normal-to-mild on the right) - amygdala atrophy (moderate on the left, mild on the right) For the ventricles: - lateral ventricle is free from enlargement or excessive growth - 3rd ventricle maintains its normal volume without signs of enlargement - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - 4th ventricle remains within normal size parameters, with no enlargement detected - normal-to-mild enlargement of the external csf	SD	We have the following subject's personal information: - The subject is a female of 72.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203948568_01864_MR_Sagittal_MP-Rage_br_raw_20230209093332949_I10183206	On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral hippocampus atrophy - basal forebrain appears structurally intact with no atrophic changes - amygdala atrophy (severe on the left, moderate on the right) - the ventral dc shows no structural abnormalities indicative of atrophy - caudate atrophy (moderate on the left, mild on the right) - moderate bilateral accumbens atrophy - thalamus remains normal, with no signs of tissue loss - putamen atrophy (mild on the left, normal-to-mild on the right) - normal-to-mild bilateral pallidum atrophy For the ventricles: - no observable enlargement or abnormal growth in the 3rd ventricle - inf. lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - no enlargement observed in the 4th ventricle - lateral ventricle is free from enlargement or excessive growth - normal-to-mild enlargement of the external csf For the cerebral cortex: - the parietal lobe shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), frontal operculum (normal-to-mild atrophy on the left) and posterior insula (normal-to-mild atrophy on the left) - mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy both left/right), entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and posterior cingulate gyrus (normal-to-mild atrophy on the right) - frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (mild atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the right) and middle frontal gyrus (normal-to-mild atrophy on the right) - no observable atrophic alterations in the occipital lobe - temporal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy both left/right) and fusiform gyrus (normal-to-mild atrophy on the left)	bvFTD	We have the following subject's personal information: - The subject is a male of 59.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203955366_03665_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451040	On a T1-weighted brain MRI we observed: For the ventricles: - the 4th ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the 3rd ventricle - no signs of enlargement detected in the external csf - normal-to-mild bilateral inf. lateral ventricle enlargement - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) For the cerebral cortex: - no observable atrophic alterations in the frontal lobe - limbic cortex remains normal, with no signs of tissue loss - no observable atrophic alterations in the insular cortex - temporal lobe appears structurally intact with no atrophic changes - parietal lobe maintains its normal morphology without atrophic features - occipital lobe appears structurally intact with no atrophic changes For the subcortical structures: - no observable atrophic alterations in the caudate - normal-to-mild bilateral putamen atrophy - amygdala maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the thalamus - basal forebrain atrophy (normal on the left, normal-to-mild on the right) - hippocampus appears structurally intact with no atrophic changes - normal-to-mild bilateral ventral dc atrophy - accumbens atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral pallidum atrophy	CN	We have the following subject's personal information: - The subject is a female of 24.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203137272_01273_MR_Sagittal_MP-Rage_br_raw_20230206162542918_I10181633	On a T1-weighted brain MRI we observed: For the cerebral cortex: - limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the right) - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: lateral orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), gyrus rectus (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the left) - temporal lobe maintains its normal morphology without atrophic features - the occipital lobe shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the parietal lobe - insular cortex maintains its normal morphology without atrophic features For the subcortical structures: - thalamus atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral caudate atrophy - hippocampus atrophy (normal on the left, normal-to-mild on the right) - pallidum atrophy (normal-to-mild on the left, normal on the right) - no evidence of atrophy or degeneration in the putamen - no observable atrophic alterations in the amygdala - no evidence of atrophy or degeneration in the basal forebrain - accumbens atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral ventral dc atrophy For the ventricles: - no abnormal enlargement observed in the inf. lateral ventricle - 3rd ventricle is free from enlargement or excessive growth - no pathological changes consistent with enlargement noted in the 4th ventricle - external csf appears structurally intact, with no evidence of enlargement - lateral ventricle enlargement (mild on the left, moderate on the right)	CN	We have the following subject's personal information: - The subject is a female of 24.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203412030_01031_MR_Sagittal_MP-Rage_br_raw_20230206164632938_I10181769	On a T1-weighted brain MRI we observed: For the subcortical structures: - the basal forebrain shows no structural abnormalities indicative of atrophy - pallidum appears structurally intact with no atrophic changes - accumbens presents with a healthy appearance, free from atrophy - ventral dc presents with a healthy appearance, free from atrophy - normal-to-mild bilateral caudate atrophy - no signs of atrophy detected in the hippocampus - normal-to-mild bilateral putamen atrophy - no observable atrophic alterations in the amygdala - thalamus appears structurally intact with no atrophic changes For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - normal-to-mild enlargement of the external csf - lateral ventricle is free from enlargement or excessive growth - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - no observable enlargement or abnormal growth in the 4th ventricle For the cerebral cortex: - mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), planum temporale (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy both left/right) and transverse temporal gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: sup. parietal lobule (normal-to-mild atrophy both left/right), angular gyrus (normal-to-mild atrophy both left/right) and postcentral gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), anterior insula (normal-to-mild atrophy on the right) and central operculum (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the occipital lobe - limbic cortex appears structurally intact with no atrophic changes - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: triangular inf. frontal gyrus (normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the right)	CN	We have the following subject's personal information: - The subject is a male of 64.0 years old. - He has 17.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203859805_01505_MR_Sagittal_MP-Rage_br_raw_20230206172921852_I10182096	On a T1-weighted brain MRI we observed: For the cerebral cortex: - no pathological changes consistent with atrophy detected in the occipital lobe - no signs of atrophy detected in the limbic cortex - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right) and postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the frontal lobe - insular cortex appears structurally intact with no atrophic changes - the temporal lobe shows no structural abnormalities indicative of atrophy For the subcortical structures: - normal-to-mild bilateral putamen atrophy - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - caudate atrophy (normal on the left, normal-to-mild on the right) - hippocampus atrophy (normal-to-mild on the left, normal on the right) - mild bilateral thalamus atrophy - accumbens atrophy (normal on the left, normal-to-mild on the right) - pallidum atrophy (normal-to-mild on the left, normal on the right) - no degenerative or atrophic changes noted in the amygdala - ventral dc atrophy (normal-to-mild on the left, mild on the right) For the ventricles: - no abnormal enlargement observed in the lateral ventricle - normal-to-mild enlargement of the external csf - inf. lateral ventricle is free from enlargement or excessive growth - normal-to-mild enlargement of the 3rd ventricle - no observable enlargement or abnormal growth in the 4th ventricle	CN	We have the following subject's personal information: - The subject is a male of 28.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203424200_01002_MR_Sagittal_MP-Rage_br_raw_20230206132639815_I10181006	On a T1-weighted brain MRI we observed: For the cerebral cortex: - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: posterior orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy on the right) and precentral gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy both left/right) and angular gyrus (normal-to-mild atrophy both left/right) - the insular cortex shows no structural abnormalities indicative of atrophy - occipital lobe remains normal, with no signs of tissue loss - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the right), planum polare (normal-to-mild atrophy on the left) and temporal pole (normal-to-mild atrophy on the left) For the subcortical structures: - putamen maintains its normal morphology without atrophic features - the ventral dc shows no structural abnormalities indicative of atrophy - accumbens atrophy (normal-to-mild on the left, normal on the right) - thalamus appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the amygdala - no signs of atrophy detected in the hippocampus - caudate presents with a healthy appearance, free from atrophy - pallidum maintains its normal morphology without atrophic features - basal forebrain atrophy (normal-to-mild on the left, normal on the right) For the ventricles: - no observable enlargement or abnormal growth in the external csf - the lateral ventricle shows no structural abnormalities indicative of enlargement - 3rd ventricle is free from enlargement or excessive growth - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - 4th ventricle maintains its normal volume without signs of enlargement	CN	We have the following subject's personal information: - The subject is a female of 54.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203208248_01840_MR_Sagittal_MP-Rage_br_raw_20230124205743547_I10178463	On a T1-weighted brain MRI we observed: For the subcortical structures: - no pathological changes consistent with atrophy detected in the basal forebrain - hippocampus remains normal, with no signs of tissue loss - no signs of atrophy detected in the pallidum - putamen remains normal, with no signs of tissue loss - the thalamus shows no structural abnormalities indicative of atrophy - amygdala appears structurally intact with no atrophic changes - caudate atrophy (normal-to-mild on the left, normal on the right) - ventral dc appears structurally intact with no atrophic changes - no signs of atrophy detected in the accumbens For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - normal-to-mild enlargement of the external csf - no pathological changes consistent with enlargement noted in the 4th ventricle - normal-to-mild bilateral inf. lateral ventricle enlargement - no observable enlargement or abnormal growth in the lateral ventricle For the cerebral cortex: - parietal lobe remains normal, with no signs of tissue loss - frontal lobe maintains its normal morphology without atrophic features - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the right) - no pathological changes consistent with atrophy detected in the temporal lobe - occipital lobe maintains its normal morphology without atrophic features - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: frontal operculum (normal-to-mild atrophy both left/right), parietal operculum (normal-to-mild atrophy on the right) and anterior insula (normal-to-mild atrophy on the right)	CN	We have the following subject's personal information: - The subject is a male of 47.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203424662_01262_MR_Sagittal_MP-Rage_br_raw_20230206140046807_I10181116	On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left) and precuneus (normal-to-mild atrophy on the left) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the left) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the right) and inf. temporal gyrus (normal-to-mild atrophy on the right) - limbic cortex maintains its normal morphology without atrophic features - no evidence of atrophy or degeneration in the insular cortex - occipital lobe appears structurally intact with no atrophic changes For the subcortical structures: - no signs of atrophy detected in the pallidum - no evidence of atrophy or degeneration in the putamen - normal-to-mild bilateral accumbens atrophy - hippocampus atrophy (normal-to-mild on the left, normal on the right) - no pathological changes consistent with atrophy detected in the ventral dc - no observable atrophic alterations in the thalamus - no signs of atrophy detected in the basal forebrain - caudate remains normal, with no signs of tissue loss - amygdala remains normal, with no signs of tissue loss For the ventricles: - lateral ventricle maintains its normal volume without signs of enlargement - no enlargement observed in the 3rd ventricle - external csf is free from enlargement or excessive growth - no signs of enlargement detected in the 4th ventricle - no observable enlargement or abnormal growth in the inf. lateral ventricle	CN	We have the following subject's personal information: - The subject is a male of 54.0 years old. - He has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203214809_02901_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10178019	On a T1-weighted brain MRI we observed: For the ventricles: - no abnormal enlargement observed in the external csf - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - lateral ventricle maintains its normal volume without signs of enlargement - 4th ventricle remains within normal size parameters, with no enlargement detected - no observable enlargement or abnormal growth in the 3rd ventricle For the subcortical structures: - no degenerative or atrophic changes noted in the ventral dc - amygdala maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the thalamus - basal forebrain appears structurally intact with no atrophic changes - no signs of atrophy detected in the putamen - hippocampus maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the pallidum - no degenerative or atrophic changes noted in the caudate - accumbens remains normal, with no signs of tissue loss For the cerebral cortex: - occipital lobe presents with a healthy appearance, free from atrophy - parietal lobe presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the insular cortex - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in transverse temporal gyrus (moderate atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the right) and planum temporale (normal-to-mild atrophy on the right) - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: medial orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), gyrus rectus (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the left), frontal pole (normal-to-mild atrophy on the right) and anterior orbital gyrus (normal-to-mild atrophy on the left) - no evidence of atrophy or degeneration in the limbic cortex	CN	We have the following subject's personal information: - The subject is a male of 32.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203788637_02738_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176931	On a T1-weighted brain MRI we observed: For the subcortical structures: - the ventral dc shows no structural abnormalities indicative of atrophy - moderate bilateral amygdala atrophy - caudate atrophy (normal-to-mild on the left, mild on the right) - pallidum atrophy (normal on the left, normal-to-mild on the right) - thalamus appears structurally intact with no atrophic changes - mild bilateral accumbens atrophy - mild bilateral hippocampus atrophy - no evidence of atrophy or degeneration in the basal forebrain - putamen atrophy (normal-to-mild on the left, mild on the right) For the ventricles: - 4th ventricle is free from enlargement or excessive growth - normal-to-mild bilateral lateral ventricle enlargement - normal-to-mild enlargement of the 3rd ventricle - moderate bilateral inf. lateral ventricle enlargement - mild enlargement of the external csf For the cerebral cortex: - no degenerative or atrophic changes noted in the frontal lobe - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the right) and posterior insula (normal-to-mild atrophy on the right) - normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: lingual gyrus (mild atrophy on the left), occipital fusiform gyrus (normal-to-mild atrophy on the right), inf. occipital gyrus (normal-to-mild atrophy on the left), cuneus (normal-to-mild atrophy on the left), sup. occipital gyrus (normal-to-mild atrophy on the left), middle occipital gyrus (normal-to-mild atrophy on the right) and occipital pole (normal-to-mild atrophy on the left) - mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the parietal lobe - temporal lobe atrophy (moderate on the left, severe on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and moderate atrophy on the right), temporal pole (moderate atrophy both left/right), inf. temporal gyrus (mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. temporal gyrus (mild atrophy on the right), planum polare (mild atrophy on the right) and planum temporale (normal-to-mild atrophy on the right)	bvFTD	We have the following subject's personal information: - The subject is a male of 73.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203129855_03552_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450920	On a T1-weighted brain MRI we observed: For the ventricles: - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - no signs of enlargement detected in the 4th ventricle - no signs of enlargement detected in the 3rd ventricle - no observable enlargement or abnormal growth in the lateral ventricle - mild enlargement of the external csf For the subcortical structures: - pallidum atrophy (mild on the left, normal-to-mild on the right) - mild bilateral hippocampus atrophy - ventral dc atrophy (mild on the left, normal-to-mild on the right) - amygdala atrophy (moderate on the left, mild on the right) - mild bilateral accumbens atrophy - the basal forebrain shows no structural abnormalities indicative of atrophy - thalamus atrophy (mild on the left, normal on the right) - putamen atrophy (mild on the left, normal-to-mild on the right) - caudate atrophy (mild on the left, normal-to-mild on the right) For the cerebral cortex: - parietal lobe presents with a healthy appearance, free from atrophy - temporal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the right) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), posterior insula (normal-to-mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the left) - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: lingual gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. occipital gyrus (normal-to-mild atrophy both left/right), calcarine cortex (normal-to-mild atrophy on the left) and inf. occipital gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy both left/right), parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the left) - frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: medial orbital gyrus (mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy both left/right), supplementary motor cortex (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the right) and anterior orbital gyrus (normal-to-mild atrophy on the left)	SD	We have the following subject's personal information: - The subject is a male of 76.0 years old. - He has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203888981_02188_MR_Sagittal_MP-Rage_br_raw_20230206184523694_I10182636	On a T1-weighted brain MRI we observed: For the subcortical structures: - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral pallidum atrophy - amygdala atrophy (normal on the left, normal-to-mild on the right) - the thalamus shows no structural abnormalities indicative of atrophy - mild bilateral putamen atrophy - hippocampus atrophy (normal-to-mild on the left, mild on the right) - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral caudate atrophy - no degenerative or atrophic changes noted in the ventral dc For the cerebral cortex: - parietal lobe remains normal, with no signs of tissue loss - occipital lobe presents with a healthy appearance, free from atrophy - frontal lobe presents with a healthy appearance, free from atrophy - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: parahippocampal gyrus (normal-to-mild atrophy both left/right), entorhinal area (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy both left/right) and posterior cingulate gyrus (normal-to-mild atrophy on the left) - no signs of atrophy detected in the insular cortex - temporal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy on the right), transverse temporal gyrus (normal-to-mild atrophy on the left) and planum polare (normal-to-mild atrophy on the right) For the ventricles: - external csf maintains its normal volume without signs of enlargement - normal-to-mild bilateral lateral ventricle enlargement - 4th ventricle maintains its normal volume without signs of enlargement - the 3rd ventricle shows no structural abnormalities indicative of enlargement - inf. lateral ventricle enlargement (mild on the left, moderate on the right)	bvFTD	We have the following subject's personal information: - The subject is a male of 76.0 years old. - He has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. His standard CDR sum of boxes is 12.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203146797_01794_MR_Sagittal_MP-Rage_br_raw_20230124205359108_I10178431	On a T1-weighted brain MRI we observed: For the ventricles: - normal-to-mild enlargement of the external csf - 3rd ventricle maintains its normal volume without signs of enlargement - 4th ventricle maintains its normal volume without signs of enlargement - no observable enlargement or abnormal growth in the lateral ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement For the cerebral cortex: - no evidence of atrophy or degeneration in the temporal lobe - frontal lobe maintains its normal morphology without atrophic features - no signs of atrophy detected in the limbic cortex - occipital lobe remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the parietal lobe - no evidence of atrophy or degeneration in the insular cortex For the subcortical structures: - normal-to-mild bilateral thalamus atrophy - caudate atrophy (normal-to-mild on the left, normal on the right) - hippocampus atrophy (normal on the left, normal-to-mild on the right) - no evidence of atrophy or degeneration in the putamen - basal forebrain atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral ventral dc atrophy - no observable atrophic alterations in the accumbens - pallidum atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral amygdala atrophy	CN	We have the following subject's personal information: - The subject is a female of 48.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203743678_02874_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177050	On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement or abnormal growth in the inf. lateral ventricle - 3rd ventricle remains within normal size parameters, with no enlargement detected - no signs of enlargement detected in the external csf - no signs of enlargement detected in the lateral ventricle - 4th ventricle is free from enlargement or excessive growth For the subcortical structures: - no degenerative or atrophic changes noted in the ventral dc - no degenerative or atrophic changes noted in the amygdala - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the thalamus - no evidence of atrophy or degeneration in the accumbens - putamen atrophy (normal-to-mild on the left, normal on the right) - pallidum appears structurally intact with no atrophic changes - no observable atrophic alterations in the caudate - no signs of atrophy detected in the hippocampus For the cerebral cortex: - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the left) and posterior cingulate gyrus (normal-to-mild atrophy on the left) - insular cortex presents with a healthy appearance, free from atrophy - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the right) - occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: sup. occipital gyrus (normal-to-mild atrophy on the left), cuneus (normal-to-mild atrophy on the right) and inf. occipital gyrus (normal-to-mild atrophy on the left) - the parietal lobe shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the temporal lobe	CN	We have the following subject's personal information: - The subject is a female of 37.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203809961_03160_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178326	On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus (mild atrophy both left/right), angular gyrus (normal-to-mild atrophy on the right), supramarginal gyrus (normal-to-mild atrophy on the left), precuneus (normal-to-mild atrophy on the left) and sup. parietal lobule (normal-to-mild atrophy on the left) - moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right), anterior insula (mild atrophy both left/right), posterior insula (mild atrophy both left/right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy both left/right) - occipital lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: inf. occipital gyrus (normal-to-mild atrophy both left/right), sup. occipital gyrus (normal-to-mild atrophy both left/right), middle occipital gyrus (normal-to-mild atrophy both left/right), calcarine cortex (normal-to-mild atrophy both left/right), cuneus (normal-to-mild atrophy both left/right), lingual gyrus (normal-to-mild atrophy both left/right) and occipital pole (normal-to-mild atrophy on the left) - moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left/right), gyrus rectus (mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy both left/right), precentral gyrus (mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), supplementary motor cortex (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left) and precentral gyrus medial segment (normal-to-mild atrophy on the right) - mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right), transverse temporal gyrus (mild atrophy both left/right), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy both left/right) and sup. temporal gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), entorhinal area (normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left) For the ventricles: - normal-to-mild enlargement of the external csf - severe bilateral inf. lateral ventricle enlargement - 4th ventricle remains within normal size parameters, with no enlargement detected - moderate enlargement of the 3rd ventricle - severe bilateral lateral ventricle enlargement For the subcortical structures: - normal-to-mild bilateral pallidum atrophy - moderate bilateral caudate atrophy - moderate bilateral accumbens atrophy - mild bilateral amygdala atrophy - moderate bilateral putamen atrophy - basal forebrain presents with a healthy appearance, free from atrophy - thalamus remains normal, with no signs of tissue loss - no observable atrophic alterations in the ventral dc - hippocampus atrophy (normal-to-mild on the left, mild on the right)	bvFTD	We have the following subject's personal information: - The subject is a male of 49.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203983272_01278_MR_Sagittal_MP-Rage_br_raw_20230206170519452_I10181917	On a T1-weighted brain MRI we observed: For the subcortical structures: - putamen atrophy (normal on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the amygdala - hippocampus maintains its normal morphology without atrophic features - ventral dc presents with a healthy appearance, free from atrophy - basal forebrain presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the thalamus - pallidum appears structurally intact with no atrophic changes - normal-to-mild bilateral accumbens atrophy - no evidence of atrophy or degeneration in the caudate For the cerebral cortex: - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus (normal-to-mild atrophy on the left), gyrus rectus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left) and precentral gyrus medial segment (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the occipital lobe - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: frontal operculum (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy on the left) - parietal lobe remains normal, with no signs of tissue loss - temporal lobe maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the limbic cortex For the ventricles: - external csf maintains its normal volume without signs of enlargement - normal-to-mild enlargement of the 3rd ventricle - no signs of enlargement detected in the lateral ventricle - no signs of enlargement detected in the inf. lateral ventricle - normal-to-mild enlargement of the 4th ventricle	CN	We have the following subject's personal information: - The subject is a female of 52.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203212277_03771_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451144	On a T1-weighted brain MRI we observed: For the ventricles: - inf. lateral ventricle enlargement (moderate on the left, mild on the right) - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - normal-to-mild enlargement of the 3rd ventricle - no pathological changes consistent with enlargement noted in the 4th ventricle - no enlargement observed in the external csf For the subcortical structures: - no evidence of atrophy or degeneration in the ventral dc - accumbens atrophy (mild on the left, normal-to-mild on the right) - basal forebrain maintains its normal morphology without atrophic features - hippocampus atrophy (moderate on the left, normal on the right) - no pathological changes consistent with atrophy detected in the putamen - amygdala atrophy (severe on the left, mild on the right) - thalamus presents with a healthy appearance, free from atrophy - normal-to-mild bilateral caudate atrophy - no signs of atrophy detected in the pallidum For the cerebral cortex: - insular cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left) - no pathological changes consistent with atrophy detected in the parietal lobe - frontal lobe remains normal, with no signs of tissue loss - temporal lobe atrophy (moderate on the left, normal on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left), temporal pole (moderate atrophy on the left), sup. temporal gyrus (normal-to-mild atrophy on the left) and planum polare (normal-to-mild atrophy on the left) - occipital lobe remains normal, with no signs of tissue loss - limbic cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy both left/right), anterior cingulate gyrus (mild atrophy on the left), posterior cingulate gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the left)	SD	We have the following subject's personal information: - The subject is a female of 56.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203977632_02237_MR_Sagittal_MP-Rage_br_raw_20230206180257105_I10182344	On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle remains within normal size parameters, with no enlargement detected - inf. lateral ventricle maintains its normal volume without signs of enlargement - lateral ventricle appears structurally intact, with no evidence of enlargement - 4th ventricle remains within normal size parameters, with no enlargement detected - the external csf shows no structural abnormalities indicative of enlargement For the subcortical structures: - amygdala maintains its normal morphology without atrophic features - no observable atrophic alterations in the pallidum - accumbens appears structurally intact with no atrophic changes - no observable atrophic alterations in the thalamus - normal-to-mild bilateral basal forebrain atrophy - no observable atrophic alterations in the putamen - the caudate shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the ventral dc - the hippocampus shows no structural abnormalities indicative of atrophy For the cerebral cortex: - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy on the left) - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: lateral orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the left) and subcallosal area (normal-to-mild atrophy on the right) - no observable atrophic alterations in the limbic cortex - no pathological changes consistent with atrophy detected in the occipital lobe - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in transverse temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and fusiform gyrus (normal-to-mild atrophy both left/right) - insular cortex maintains its normal morphology without atrophic features	CN	We have the following subject's personal information: - The subject is a male of 54.0 years old. - He has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203471402_03207_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178329	On a T1-weighted brain MRI we observed: For the ventricles: - lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - inf. lateral ventricle enlargement (normal on the left, moderate on the right) - 4th ventricle remains within normal size parameters, with no enlargement detected - normal-to-mild enlargement of the 3rd ventricle - mild enlargement of the external csf For the cerebral cortex: - mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right), entorhinal area (normal-to-mild atrophy on the left and mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the left) - parietal lobe remains normal, with no signs of tissue loss - temporal lobe atrophy (mild on the left, moderate on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (mild atrophy both left/right), fusiform gyrus (mild atrophy on the right), planum polare (normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the right) - mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (moderate atrophy both left/right), posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), frontal operculum (normal-to-mild atrophy both left/right) and central operculum (normal-to-mild atrophy on the left) - frontal lobe atrophy (mild on the left, moderate on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), lateral orbital gyrus (mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), frontal pole (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the right) and precentral gyrus (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the occipital lobe For the subcortical structures: - putamen atrophy (normal-to-mild on the left, mild on the right) - moderate bilateral accumbens atrophy - the basal forebrain shows no structural abnormalities indicative of atrophy - thalamus remains normal, with no signs of tissue loss - mild bilateral caudate atrophy - amygdala atrophy (moderate on the left, severe on the right) - pallidum atrophy (normal on the left, normal-to-mild on the right) - hippocampus atrophy (normal-to-mild on the left, moderate on the right) - no observable atrophic alterations in the ventral dc	bvFTD	We have the following subject's personal information: - The subject is a female of 72.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203956632_01235_MR_Sagittal_MP-Rage_br_raw_20230206135959523_I10181113	On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle remains within normal size parameters, with no enlargement detected - normal-to-mild bilateral lateral ventricle enlargement - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - normal-to-mild enlargement of the 4th ventricle - normal-to-mild enlargement of the external csf For the cerebral cortex: - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), frontal operculum (normal-to-mild atrophy both left/right), central operculum (normal-to-mild atrophy on the left), parietal operculum (normal-to-mild atrophy on the left) and posterior insula (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the occipital lobe - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy both left/right), entorhinal area (normal-to-mild atrophy on the left) and posterior cingulate gyrus (normal-to-mild atrophy on the left) - parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. parietal lobule (normal-to-mild atrophy both left/right) and postcentral gyrus (normal-to-mild atrophy both left/right) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left), frontal pole (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left), sup. frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the right) and medial frontal cortex (normal-to-mild atrophy on the left) - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the left) For the subcortical structures: - no evidence of atrophy or degeneration in the ventral dc - basal forebrain remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the thalamus - no evidence of atrophy or degeneration in the hippocampus - normal-to-mild bilateral pallidum atrophy - putamen atrophy (normal-to-mild on the left, normal on the right) - amygdala atrophy (normal on the left, normal-to-mild on the right) - accumbens appears structurally intact with no atrophic changes - normal-to-mild bilateral caudate atrophy	CN	We have the following subject's personal information: - The subject is a female of 55.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203094052_02259_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177666	On a T1-weighted brain MRI we observed: For the subcortical structures: - basal forebrain maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the thalamus - no signs of atrophy detected in the putamen - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral amygdala atrophy - hippocampus maintains its normal morphology without atrophic features - no evidence of atrophy or degeneration in the ventral dc - no signs of atrophy detected in the pallidum - caudate atrophy (normal on the left, normal-to-mild on the right) For the cerebral cortex: - frontal lobe presents with a healthy appearance, free from atrophy - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), posterior insula (normal-to-mild atrophy on the right) and central operculum (normal-to-mild atrophy on the right) - no signs of atrophy detected in the occipital lobe - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the left) and inf. temporal gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), postcentral gyrus (normal-to-mild atrophy on the left), postcentral gyrus medial segment (normal-to-mild atrophy on the left) and precuneus (normal-to-mild atrophy on the right) - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right) For the ventricles: - normal-to-mild enlargement of the external csf - no enlargement observed in the 4th ventricle - no enlargement observed in the 3rd ventricle - no abnormal enlargement observed in the lateral ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement	CN	We have the following subject's personal information: - The subject is a female of 46.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203966778_01876_MR_Sagittal_MP-Rage_br_raw_20230206175323985_I10182277	On a T1-weighted brain MRI we observed: For the cerebral cortex: - no degenerative or atrophic changes noted in the limbic cortex - insular cortex remains normal, with no signs of tissue loss - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. occipital gyrus (normal-to-mild atrophy both left/right), occipital pole (normal-to-mild atrophy both left/right), calcarine cortex (normal-to-mild atrophy on the left), inf. occipital gyrus (normal-to-mild atrophy on the right) and lingual gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the left) and precentral gyrus (normal-to-mild atrophy on the right) - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the parietal lobe For the subcortical structures: - normal-to-mild bilateral pallidum atrophy - no observable atrophic alterations in the hippocampus - basal forebrain appears structurally intact with no atrophic changes - normal-to-mild bilateral thalamus atrophy - normal-to-mild bilateral amygdala atrophy - normal-to-mild bilateral caudate atrophy - normal-to-mild bilateral putamen atrophy - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral ventral dc atrophy For the ventricles: - 3rd ventricle remains within normal size parameters, with no enlargement detected - no signs of enlargement detected in the 4th ventricle - normal-to-mild bilateral inf. lateral ventricle enlargement - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild enlargement of the external csf	bvFTD	We have the following subject's personal information: - The subject is a male of 71.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203679999_01997_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10449529	On a T1-weighted brain MRI we observed: For the cerebral cortex: - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), central operculum (normal-to-mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the right) - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left) - no evidence of atrophy or degeneration in the occipital lobe - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), postcentral gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy on the right) and sup. parietal lobule (normal-to-mild atrophy on the left) - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: medial orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left) and precentral gyrus (normal-to-mild atrophy on the right) For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - inf. lateral ventricle enlargement (normal-to-mild on the left, mild on the right) - normal-to-mild enlargement of the external csf - lateral ventricle enlargement (normal-to-mild on the left, mild on the right) - normal-to-mild enlargement of the 3rd ventricle For the subcortical structures: - normal-to-mild bilateral hippocampus atrophy - thalamus atrophy (mild on the left, normal-to-mild on the right) - no degenerative or atrophic changes noted in the accumbens - the caudate shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the amygdala - putamen maintains its normal morphology without atrophic features - normal-to-mild bilateral pallidum atrophy - ventral dc remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the basal forebrain	bvFTD	We have the following subject's personal information: - The subject is a male of 71.0 years old. - He has 15.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. His standard CDR sum of boxes is 12.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203798227_03729_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10451111	On a T1-weighted brain MRI we observed: For the cerebral cortex: - mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the left), central operculum (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy on the right) - limbic cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy both left/right), anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the occipital lobe - temporal lobe atrophy (severe on the left, mild on the right), with focal volume loss observed in the following subregions: temporal pole (moderate atrophy both left/right), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (normal-to-mild atrophy both left/right), planum polare (mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left) and planum temporale (normal-to-mild atrophy on the right) - frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left) and precentral gyrus (normal-to-mild atrophy on the left) - the parietal lobe shows no structural abnormalities indicative of atrophy For the ventricles: - 4th ventricle appears structurally intact, with no evidence of enlargement - severe bilateral inf. lateral ventricle enlargement - normal-to-mild enlargement of the external csf - lateral ventricle enlargement (moderate on the left, mild on the right) - mild enlargement of the 3rd ventricle For the subcortical structures: - putamen atrophy (moderate on the left, mild on the right) - amygdala atrophy (severe on the left, moderate on the right) - pallidum atrophy (mild on the left, normal-to-mild on the right) - ventral dc maintains its normal morphology without atrophic features - accumbens atrophy (moderate on the left, normal-to-mild on the right) - hippocampus atrophy (moderate on the left, mild on the right) - caudate atrophy (moderate on the left, normal-to-mild on the right) - thalamus atrophy (mild on the left, normal on the right) - basal forebrain appears structurally intact with no atrophic changes	SD	We have the following subject's personal information: - The subject is a female of 56.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203966778_01876_MR_Sagittal_MP-Rage_br_raw_20230206175323985_I10182277	On a T1-weighted brain MRI we observed: For the subcortical structures: - no observable atrophic alterations in the hippocampus - no observable atrophic alterations in the basal forebrain - normal-to-mild bilateral thalamus atrophy - normal-to-mild bilateral putamen atrophy - normal-to-mild bilateral ventral dc atrophy - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral amygdala atrophy - normal-to-mild bilateral caudate atrophy For the ventricles: - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild bilateral inf. lateral ventricle enlargement - 3rd ventricle maintains its normal volume without signs of enlargement - 4th ventricle maintains its normal volume without signs of enlargement - normal-to-mild enlargement of the external csf For the cerebral cortex: - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the left) and precentral gyrus (normal-to-mild atrophy on the right) - limbic cortex presents with a healthy appearance, free from atrophy - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the left) - insular cortex presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the parietal lobe - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. occipital gyrus (normal-to-mild atrophy both left/right), occipital pole (normal-to-mild atrophy both left/right), calcarine cortex (normal-to-mild atrophy on the left), inf. occipital gyrus (normal-to-mild atrophy on the right) and lingual gyrus (normal-to-mild atrophy on the right)	bvFTD	We have the following subject's personal information: - The subject is a male of 71.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203120483_03382_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450642	On a T1-weighted brain MRI we observed: For the ventricles: - no pathological changes consistent with enlargement noted in the external csf - normal-to-mild enlargement of the 3rd ventricle - mild bilateral inf. lateral ventricle enlargement - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - mild enlargement of the 4th ventricle For the cerebral cortex: - no observable atrophic alterations in the parietal lobe - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right) and posterior cingulate gyrus (normal-to-mild atrophy both left/right) - mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), frontal pole (normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the left) - occipital lobe maintains its normal morphology without atrophic features - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy both left/right), anterior insula (normal-to-mild atrophy both left/right) and posterior insula (normal-to-mild atrophy on the left) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: transverse temporal gyrus (normal-to-mild atrophy on the right), fusiform gyrus (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the right) For the subcortical structures: - thalamus atrophy (normal on the left, normal-to-mild on the right) - no signs of atrophy detected in the caudate - no evidence of atrophy or degeneration in the hippocampus - normal-to-mild bilateral amygdala atrophy - no signs of atrophy detected in the pallidum - normal-to-mild bilateral accumbens atrophy - ventral dc presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the basal forebrain - no observable atrophic alterations in the putamen	bvFTD	We have the following subject's personal information: - The subject is a male of 64.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203440939_01934_MR_Sagittal_MP-Rage_br_raw_20230209094057164_I10183241	On a T1-weighted brain MRI we observed: For the subcortical structures: - basal forebrain remains normal, with no signs of tissue loss - amygdala appears structurally intact with no atrophic changes - hippocampus maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the caudate - pallidum appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the thalamus - accumbens presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the putamen - ventral dc maintains its normal morphology without atrophic features For the cerebral cortex: - frontal lobe appears structurally intact with no atrophic changes - temporal lobe remains normal, with no signs of tissue loss - limbic cortex appears structurally intact with no atrophic changes - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy both left/right), central operculum (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy on the left) - parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. parietal lobule (normal-to-mild atrophy both left/right), postcentral gyrus medial segment (normal-to-mild atrophy both left/right) and precuneus (normal-to-mild atrophy both left/right) - no pathological changes consistent with atrophy detected in the occipital lobe For the ventricles: - 4th ventricle maintains its normal volume without signs of enlargement - 3rd ventricle maintains its normal volume without signs of enlargement - no observable enlargement or abnormal growth in the external csf - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - no enlargement observed in the lateral ventricle	bvFTD	We have the following subject's personal information: - The subject is a male of 55.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203912538_03831_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047790	On a T1-weighted brain MRI we observed: For the cerebral cortex: - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), posterior insula (normal-to-mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy both left/right) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left), frontal pole (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the right) - occipital lobe remains normal, with no signs of tissue loss - no signs of atrophy detected in the parietal lobe - no evidence of atrophy or degeneration in the temporal lobe For the ventricles: - no observable enlargement or abnormal growth in the 4th ventricle - normal-to-mild enlargement of the external csf - no abnormal enlargement observed in the 3rd ventricle - lateral ventricle is free from enlargement or excessive growth - inf. lateral ventricle maintains its normal volume without signs of enlargement For the subcortical structures: - normal-to-mild bilateral pallidum atrophy - mild bilateral putamen atrophy - no observable atrophic alterations in the hippocampus - ventral dc atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral caudate atrophy - no observable atrophic alterations in the basal forebrain - normal-to-mild bilateral thalamus atrophy - amygdala maintains its normal morphology without atrophic features - accumbens atrophy (normal-to-mild on the left, normal on the right)	PNFA	We have the following subject's personal information: - The subject is a female of 55.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203391632_03239_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10178045	On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: sup. parietal lobule (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the right) - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (mild atrophy on the left) - no pathological changes consistent with atrophy detected in the limbic cortex - no pathological changes consistent with atrophy detected in the frontal lobe - temporal lobe appears structurally intact with no atrophic changes - no observable atrophic alterations in the insular cortex For the subcortical structures: - hippocampus atrophy (normal on the left, normal-to-mild on the right) - the pallidum shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the putamen - no observable atrophic alterations in the ventral dc - no signs of atrophy detected in the basal forebrain - caudate remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the thalamus - amygdala appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the accumbens For the ventricles: - external csf is free from enlargement or excessive growth - no signs of enlargement detected in the inf. lateral ventricle - no enlargement observed in the lateral ventricle - no abnormal enlargement observed in the 4th ventricle - no pathological changes consistent with enlargement noted in the 3rd ventricle	CN	We have the following subject's personal information: - The subject is a female of 41.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203748920_03024_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176803	On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe appears structurally intact with no atrophic changes - temporal lobe atrophy (moderate on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild atrophy on the left), inf. temporal gyrus (mild atrophy on the left), sup. temporal gyrus (normal-to-mild atrophy on the left), planum polare (normal-to-mild atrophy on the left) and fusiform gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left), parahippocampal gyrus (mild atrophy on the left) and anterior cingulate gyrus (mild atrophy on the left) - no pathological changes consistent with atrophy detected in the occipital lobe - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left), gyrus rectus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left) and subcallosal area (normal-to-mild atrophy on the left) - insular cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild atrophy on the left) and frontal operculum (normal-to-mild atrophy on the left) For the subcortical structures: - hippocampus atrophy (moderate on the left, normal on the right) - amygdala atrophy (severe on the left, normal on the right) - the thalamus shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the basal forebrain - accumbens atrophy (mild on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the ventral dc - pallidum atrophy (normal-to-mild on the left, normal on the right) - caudate remains normal, with no signs of tissue loss - normal-to-mild bilateral putamen atrophy For the ventricles: - no observable enlargement or abnormal growth in the lateral ventricle - normal-to-mild enlargement of the external csf - normal-to-mild enlargement of the 3rd ventricle - the 4th ventricle shows no structural abnormalities indicative of enlargement - inf. lateral ventricle enlargement (severe on the left, normal on the right)	SD	We have the following subject's personal information: - The subject is a male of 64.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on behavior, comportment, and personality, corresponding to no impairment.
FTLD_203573727_02727_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176961	On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle appears structurally intact, with no evidence of enlargement - inf. lateral ventricle enlargement (mild on the left, moderate on the right) - mild enlargement of the external csf - lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - no signs of enlargement detected in the 4th ventricle For the cerebral cortex: - temporal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy both left/right), inf. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and planum temporale (normal-to-mild atrophy on the right) - no signs of atrophy detected in the occipital lobe - frontal lobe atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy on the right) and medial orbital gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), entorhinal area (normal-to-mild atrophy both left/right) and parahippocampal gyrus (normal-to-mild atrophy both left/right) - parietal lobe remains normal, with no signs of tissue loss - insular cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), frontal operculum (normal-to-mild atrophy both left/right), parietal operculum (normal-to-mild atrophy both left/right) and central operculum (normal-to-mild atrophy on the right) For the subcortical structures: - ventral dc atrophy (normal on the left, normal-to-mild on the right) - thalamus atrophy (normal on the left, normal-to-mild on the right) - pallidum atrophy (normal-to-mild on the left, mild on the right) - no pathological changes consistent with atrophy detected in the basal forebrain - caudate atrophy (mild on the left, moderate on the right) - hippocampus atrophy (normal-to-mild on the left, mild on the right) - mild bilateral putamen atrophy - amygdala atrophy (mild on the left, moderate on the right) - accumbens atrophy (mild on the left, moderate on the right)	bvFTD	We have the following subject's personal information: - The subject is a male of 67.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on behavior, comportment, and personality, corresponding to moderate impairment.
FTLD_203403697_01790_MR_Sagittal_MP-Rage_br_raw_20230206174835442_I10182241	On a T1-weighted brain MRI we observed: For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - lateral ventricle enlargement (normal-to-mild on the left, mild on the right) - mild enlargement of the external csf - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (normal on the left, mild on the right) For the cerebral cortex: - limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy both left/right) - occipital lobe presents with a healthy appearance, free from atrophy - insular cortex atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), posterior insula (normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the right) - parietal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: angular gyrus (mild atrophy on the right), precuneus (normal-to-mild atrophy both left/right), postcentral gyrus medial segment (normal-to-mild atrophy both left/right), postcentral gyrus (normal-to-mild atrophy on the left) and sup. parietal lobule (normal-to-mild atrophy on the right) - frontal lobe atrophy (normal-to-mild on the left, moderate on the right), with focal volume loss observed in the following subregions: gyrus rectus (mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the right) and orbital inf. frontal gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy both left/right) For the subcortical structures: - mild bilateral accumbens atrophy - putamen atrophy (normal-to-mild on the left, moderate on the right) - caudate atrophy (mild on the left, moderate on the right) - amygdala atrophy (normal-to-mild on the left, mild on the right) - thalamus atrophy (normal-to-mild on the left, moderate on the right) - basal forebrain appears structurally intact with no atrophic changes - hippocampus atrophy (normal-to-mild on the left, mild on the right) - ventral dc atrophy (normal-to-mild on the left, mild on the right) - pallidum atrophy (normal-to-mild on the left, mild on the right)	bvFTD	We have the following subject's personal information: - The subject is a female of 69.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203940015_02514_MR_Sagittal_MP-Rage_br_raw_20230209102908496_I10183491	On a T1-weighted brain MRI we observed: For the ventricles: - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - lateral ventricle maintains its normal volume without signs of enlargement - no signs of enlargement detected in the 3rd ventricle - no pathological changes consistent with enlargement noted in the 4th ventricle - the external csf shows no structural abnormalities indicative of enlargement For the cerebral cortex: - no observable atrophic alterations in the insular cortex - no degenerative or atrophic changes noted in the frontal lobe - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left), middle cingulate gyrus (normal-to-mild atrophy on the left) and posterior cingulate gyrus (normal-to-mild atrophy on the right) - occipital lobe appears structurally intact with no atrophic changes - temporal lobe presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the parietal lobe For the subcortical structures: - no observable atrophic alterations in the thalamus - no pathological changes consistent with atrophy detected in the pallidum - the ventral dc shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the amygdala - no degenerative or atrophic changes noted in the putamen - no degenerative or atrophic changes noted in the hippocampus - no pathological changes consistent with atrophy detected in the accumbens - caudate presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the basal forebrain	CN	We have the following subject's personal information: - The subject is a female of 57.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203681967_01768_MR_Sagittal_MP-Rage_br_raw_20230206174731756_I10182233	On a T1-weighted brain MRI we observed: For the ventricles: - lateral ventricle is free from enlargement or excessive growth - the 3rd ventricle shows no structural abnormalities indicative of enlargement - 4th ventricle remains within normal size parameters, with no enlargement detected - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the external csf For the subcortical structures: - no evidence of atrophy or degeneration in the ventral dc - normal-to-mild bilateral putamen atrophy - caudate atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral thalamus atrophy - no signs of atrophy detected in the amygdala - normal-to-mild bilateral pallidum atrophy - no evidence of atrophy or degeneration in the basal forebrain - hippocampus remains normal, with no signs of tissue loss - normal-to-mild bilateral accumbens atrophy For the cerebral cortex: - no degenerative or atrophic changes noted in the occipital lobe - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy both left/right), sup. parietal lobule (normal-to-mild atrophy both left/right) and supramarginal gyrus (normal-to-mild atrophy on the left) - temporal lobe presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the frontal lobe - insular cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the right), posterior insula (normal-to-mild atrophy on the left) and central operculum (normal-to-mild atrophy on the right) - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the left), anterior cingulate gyrus (normal-to-mild atrophy both left/right) and entorhinal area (normal-to-mild atrophy on the left)	CN	We have the following subject's personal information: - The subject is a female of 59.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203300760_03060_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178272	On a T1-weighted brain MRI we observed: For the subcortical structures: - thalamus atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral caudate atrophy - hippocampus atrophy (mild on the left, normal-to-mild on the right) - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral ventral dc atrophy - putamen atrophy (normal-to-mild on the left, normal on the right) - no signs of atrophy detected in the basal forebrain - amygdala atrophy (moderate on the left, normal-to-mild on the right) For the ventricles: - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - inf. lateral ventricle enlargement (moderate on the left, normal-to-mild on the right) - mild enlargement of the external csf - no abnormal enlargement observed in the 4th ventricle - 3rd ventricle maintains its normal volume without signs of enlargement For the cerebral cortex: - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left), posterior insula (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the right) - limbic cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), entorhinal area (mild atrophy on the left) and anterior cingulate gyrus (normal-to-mild atrophy on the left) - parietal lobe appears structurally intact with no atrophic changes - frontal lobe maintains its normal morphology without atrophic features - occipital lobe remains normal, with no signs of tissue loss - temporal lobe atrophy (moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild atrophy on the left), fusiform gyrus (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left), sup. temporal gyrus (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the right) and planum polare (normal-to-mild atrophy on the left)	SD	We have the following subject's personal information: - The subject is a male of 59.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree)
FTLD_203901165_02560_MR_Sagittal_MP-Rage_br_raw_20230209103425185_I10183512	On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement or abnormal growth in the external csf - no observable enlargement or abnormal growth in the lateral ventricle - no enlargement observed in the inf. lateral ventricle - normal-to-mild enlargement of the 4th ventricle - 3rd ventricle remains within normal size parameters, with no enlargement detected For the cerebral cortex: - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: planum polare (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the right) - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right) and posterior cingulate gyrus (normal-to-mild atrophy both left/right) - no degenerative or atrophic changes noted in the occipital lobe - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left) and posterior orbital gyrus (normal-to-mild atrophy on the right) - parietal lobe appears structurally intact with no atrophic changes - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy on the left), frontal operculum (normal-to-mild atrophy on the right) and anterior insula (normal-to-mild atrophy on the left) For the subcortical structures: - no pathological changes consistent with atrophy detected in the ventral dc - hippocampus atrophy (normal on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the basal forebrain - normal-to-mild bilateral caudate atrophy - thalamus maintains its normal morphology without atrophic features - no signs of atrophy detected in the putamen - no observable atrophic alterations in the accumbens - amygdala atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the pallidum	CN	We have the following subject's personal information: - The subject is a female of 36.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203391632_03239_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10178045	On a T1-weighted brain MRI we observed: For the ventricles: - no signs of enlargement detected in the inf. lateral ventricle - lateral ventricle appears structurally intact, with no evidence of enlargement - no pathological changes consistent with enlargement noted in the 3rd ventricle - no observable enlargement or abnormal growth in the 4th ventricle - no signs of enlargement detected in the external csf For the subcortical structures: - no pathological changes consistent with atrophy detected in the pallidum - no observable atrophic alterations in the accumbens - no observable atrophic alterations in the thalamus - no degenerative or atrophic changes noted in the putamen - no signs of atrophy detected in the basal forebrain - no signs of atrophy detected in the amygdala - ventral dc maintains its normal morphology without atrophic features - hippocampus atrophy (normal on the left, normal-to-mild on the right) - no degenerative or atrophic changes noted in the caudate For the cerebral cortex: - temporal lobe remains normal, with no signs of tissue loss - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (mild atrophy on the left) - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: sup. parietal lobule (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the right) - the insular cortex shows no structural abnormalities indicative of atrophy - frontal lobe maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the limbic cortex	CN	We have the following subject's personal information: - The subject is a female of 41.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203316074_03471_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450814	On a T1-weighted brain MRI we observed: For the ventricles: - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - no enlargement observed in the 4th ventricle - external csf remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the lateral ventricle - no observable enlargement or abnormal growth in the 3rd ventricle For the cerebral cortex: - no evidence of atrophy or degeneration in the occipital lobe - the frontal lobe shows no structural abnormalities indicative of atrophy - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the left) - no evidence of atrophy or degeneration in the insular cortex - parietal lobe remains normal, with no signs of tissue loss - limbic cortex maintains its normal morphology without atrophic features For the subcortical structures: - no observable atrophic alterations in the basal forebrain - no pathological changes consistent with atrophy detected in the caudate - thalamus maintains its normal morphology without atrophic features - the accumbens shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the putamen - amygdala appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the hippocampus - pallidum appears structurally intact with no atrophic changes - ventral dc remains normal, with no signs of tissue loss	CN	We have the following subject's personal information: - The subject is a female of 54.0 years old. - She has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203103542_03240_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177115	On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy both left/right) and sup. parietal lobule (normal-to-mild atrophy on the left) - mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right), parietal operculum (normal-to-mild atrophy both left/right) and posterior insula (normal-to-mild atrophy both left/right) - occipital lobe presents with a healthy appearance, free from atrophy - frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: supplementary motor cortex (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (mild atrophy on the left), gyrus rectus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (mild atrophy on the left), frontal pole (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus medial segment (normal-to-mild atrophy on the right) and posterior orbital gyrus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the temporal lobe - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right), parahippocampal gyrus (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) For the ventricles: - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild enlargement of the 3rd ventricle - normal-to-mild enlargement of the external csf - 4th ventricle appears structurally intact, with no evidence of enlargement - inf. lateral ventricle enlargement (mild on the left, normal on the right) For the subcortical structures: - no pathological changes consistent with atrophy detected in the basal forebrain - hippocampus atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the ventral dc - putamen atrophy (mild on the left, normal-to-mild on the right) - pallidum atrophy (normal-to-mild on the left, normal on the right) - caudate atrophy (moderate on the left, mild on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - mild bilateral accumbens atrophy - amygdala atrophy (normal-to-mild on the left, normal on the right)	bvFTD	We have the following subject's personal information: - The subject is a female of 78.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 6.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203391632_03239_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10178045	On a T1-weighted brain MRI we observed: For the subcortical structures: - no pathological changes consistent with atrophy detected in the basal forebrain - thalamus appears structurally intact with no atrophic changes - the pallidum shows no structural abnormalities indicative of atrophy - amygdala maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the putamen - hippocampus atrophy (normal on the left, normal-to-mild on the right) - the accumbens shows no structural abnormalities indicative of atrophy - caudate maintains its normal morphology without atrophic features - the ventral dc shows no structural abnormalities indicative of atrophy For the ventricles: - no signs of enlargement detected in the 3rd ventricle - no signs of enlargement detected in the external csf - lateral ventricle appears structurally intact, with no evidence of enlargement - inf. lateral ventricle maintains its normal volume without signs of enlargement - no enlargement observed in the 4th ventricle For the cerebral cortex: - no degenerative or atrophic changes noted in the frontal lobe - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: sup. parietal lobule (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the right) - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (mild atrophy on the left) - insular cortex appears structurally intact with no atrophic changes - limbic cortex remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the temporal lobe	CN	We have the following subject's personal information: - The subject is a female of 41.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203808293_02390_MR_Sagittal_MP-Rage_br_raw_20230206180655212_I10182372	On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc appears structurally intact with no atrophic changes - no signs of atrophy detected in the hippocampus - the thalamus shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the amygdala - no observable atrophic alterations in the putamen - normal-to-mild bilateral caudate atrophy - pallidum presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the accumbens - no evidence of atrophy or degeneration in the basal forebrain For the cerebral cortex: - no degenerative or atrophic changes noted in the frontal lobe - occipital lobe maintains its normal morphology without atrophic features - no evidence of atrophy or degeneration in the insular cortex - parietal lobe maintains its normal morphology without atrophic features - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the left), temporal pole (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the left) - the limbic cortex shows no structural abnormalities indicative of atrophy For the ventricles: - no pathological changes consistent with enlargement noted in the 3rd ventricle - no pathological changes consistent with enlargement noted in the external csf - lateral ventricle appears structurally intact, with no evidence of enlargement - inf. lateral ventricle is free from enlargement or excessive growth - 4th ventricle appears structurally intact, with no evidence of enlargement	CN	We have the following subject's personal information: - The subject is a female of 57.0 years old. - She has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203974853_02357_MR_Sagittal_MP-Rage_br_raw_20230206160041790_I10181513	On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe presents with a healthy appearance, free from atrophy - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), fusiform gyrus (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the right), temporal pole (normal-to-mild atrophy both left/right) and transverse temporal gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the right) and posterior orbital gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the occipital lobe - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy both left/right) - no pathological changes consistent with atrophy detected in the limbic cortex For the ventricles: - lateral ventricle is free from enlargement or excessive growth - no enlargement observed in the 3rd ventricle - mild enlargement of the external csf - 4th ventricle remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the inf. lateral ventricle For the subcortical structures: - no pathological changes consistent with atrophy detected in the pallidum - normal-to-mild bilateral caudate atrophy - ventral dc appears structurally intact with no atrophic changes - hippocampus appears structurally intact with no atrophic changes - thalamus appears structurally intact with no atrophic changes - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral putamen atrophy - basal forebrain remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the amygdala	CN	We have the following subject's personal information: - The subject is a female of 43.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203266648_01846_MR_Sagittal_MP-Rage_br_raw_20230206151900156_I10181365	On a T1-weighted brain MRI we observed: For the subcortical structures: - no pathological changes consistent with atrophy detected in the accumbens - hippocampus atrophy (normal-to-mild on the left, normal on the right) - no evidence of atrophy or degeneration in the caudate - basal forebrain appears structurally intact with no atrophic changes - normal-to-mild bilateral ventral dc atrophy - normal-to-mild bilateral thalamus atrophy - the amygdala shows no structural abnormalities indicative of atrophy - pallidum appears structurally intact with no atrophic changes - no observable atrophic alterations in the putamen For the cerebral cortex: - no pathological changes consistent with atrophy detected in the occipital lobe - insular cortex remains normal, with no signs of tissue loss - frontal lobe maintains its normal morphology without atrophic features - temporal lobe remains normal, with no signs of tissue loss - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the right) - the parietal lobe shows no structural abnormalities indicative of atrophy For the ventricles: - the external csf shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the 4th ventricle - lateral ventricle is free from enlargement or excessive growth - 3rd ventricle is free from enlargement or excessive growth - no enlargement observed in the inf. lateral ventricle	CN	We have the following subject's personal information: - The subject is a female of 55.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203933841_02143_MR_Sagittal_MP-Rage_br_raw_20230124205938681_I10178482	On a T1-weighted brain MRI we observed: For the cerebral cortex: - temporal lobe atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the parietal lobe - frontal lobe atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: gyrus rectus (mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (mild atrophy both left/right), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy both left/right), supplementary motor cortex (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left) and anterior orbital gyrus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the occipital lobe - insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (normal-to-mild atrophy both left/right) and central operculum (normal-to-mild atrophy both left/right) For the subcortical structures: - hippocampus appears structurally intact with no atrophic changes - ventral dc maintains its normal morphology without atrophic features - caudate atrophy (mild on the left, normal on the right) - no evidence of atrophy or degeneration in the basal forebrain - putamen atrophy (mild on the left, normal on the right) - amygdala atrophy (moderate on the left, normal on the right) - accumbens atrophy (moderate on the left, mild on the right) - no pathological changes consistent with atrophy detected in the thalamus - the pallidum shows no structural abnormalities indicative of atrophy For the ventricles: - no enlargement observed in the 4th ventricle - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (mild on the left, normal on the right) - normal-to-mild enlargement of the external csf	bvFTD	We have the following subject's personal information: - The subject is a female of 54.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203617026_02621_MR_Sagittal_MP-Rage_br_raw_20230206161609957_I10181581	On a T1-weighted brain MRI we observed: For the subcortical structures: - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - mild bilateral putamen atrophy - thalamus atrophy (mild on the left, normal-to-mild on the right) - mild bilateral hippocampus atrophy - amygdala atrophy (normal-to-mild on the left, mild on the right) - mild bilateral ventral dc atrophy - accumbens atrophy (mild on the left, normal-to-mild on the right) - mild bilateral pallidum atrophy - caudate atrophy (moderate on the left, mild on the right) For the cerebral cortex: - the parietal lobe shows no structural abnormalities indicative of atrophy - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: frontal operculum (normal-to-mild atrophy on the right) and anterior insula (normal-to-mild atrophy on the left) - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), parahippocampal gyrus (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the left) and anterior cingulate gyrus (normal-to-mild atrophy on the right) - the temporal lobe shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the occipital lobe - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) and triangular inf. frontal gyrus (normal-to-mild atrophy on the left) For the ventricles: - mild bilateral inf. lateral ventricle enlargement - mild bilateral lateral ventricle enlargement - the 4th ventricle shows no structural abnormalities indicative of enlargement - no abnormal enlargement observed in the external csf - normal-to-mild enlargement of the 3rd ventricle	PNFA	We have the following subject's personal information: - The subject is a male of 69.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 8.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203719527_02721_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177796	On a T1-weighted brain MRI we observed: For the subcortical structures: - amygdala maintains its normal morphology without atrophic features - caudate presents with a healthy appearance, free from atrophy - putamen remains normal, with no signs of tissue loss - no observable atrophic alterations in the accumbens - no degenerative or atrophic changes noted in the basal forebrain - normal-to-mild bilateral thalamus atrophy - no pathological changes consistent with atrophy detected in the pallidum - hippocampus atrophy (normal-to-mild on the left, normal on the right) - no pathological changes consistent with atrophy detected in the ventral dc For the ventricles: - normal-to-mild enlargement of the external csf - lateral ventricle maintains its normal volume without signs of enlargement - 3rd ventricle remains within normal size parameters, with no enlargement detected - no enlargement observed in the 4th ventricle - no signs of enlargement detected in the inf. lateral ventricle For the cerebral cortex: - no evidence of atrophy or degeneration in the limbic cortex - no evidence of atrophy or degeneration in the parietal lobe - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle occipital gyrus (mild atrophy on the right) and lingual gyrus (normal-to-mild atrophy on the left) - no signs of atrophy detected in the frontal lobe - no degenerative or atrophic changes noted in the insular cortex - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left), planum polare (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the right) and fusiform gyrus (normal-to-mild atrophy on the left)	CN	We have the following subject's personal information: - The subject is a female of 25.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203120724_01422_MR_Sagittal_MP-Rage_br_raw_20230124211357486_I10178571	On a T1-weighted brain MRI we observed: For the ventricles: - external csf remains within normal size parameters, with no enlargement detected - 4th ventricle remains within normal size parameters, with no enlargement detected - no enlargement observed in the lateral ventricle - inf. lateral ventricle enlargement (normal-to-mild on the left, mild on the right) - normal-to-mild enlargement of the 3rd ventricle For the cerebral cortex: - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the left) and transverse temporal gyrus (normal-to-mild atrophy on the right) - no observable atrophic alterations in the parietal lobe - insular cortex appears structurally intact with no atrophic changes - the limbic cortex shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the occipital lobe - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) and gyrus rectus (normal-to-mild atrophy on the left) For the subcortical structures: - hippocampus presents with a healthy appearance, free from atrophy - amygdala remains normal, with no signs of tissue loss - pallidum presents with a healthy appearance, free from atrophy - accumbens presents with a healthy appearance, free from atrophy - thalamus appears structurally intact with no atrophic changes - basal forebrain maintains its normal morphology without atrophic features - ventral dc remains normal, with no signs of tissue loss - the putamen shows no structural abnormalities indicative of atrophy - caudate atrophy (normal-to-mild on the left, normal on the right)	CN	We have the following subject's personal information: - The subject is a male of 66.0 years old. - He has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203927782_02282_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178057	On a T1-weighted brain MRI we observed: For the subcortical structures: - normal-to-mild bilateral caudate atrophy - amygdala atrophy (moderate on the left, mild on the right) - no degenerative or atrophic changes noted in the ventral dc - putamen atrophy (normal-to-mild on the left, normal on the right) - thalamus remains normal, with no signs of tissue loss - normal-to-mild bilateral accumbens atrophy - basal forebrain maintains its normal morphology without atrophic features - hippocampus atrophy (mild on the left, normal-to-mild on the right) - pallidum remains normal, with no signs of tissue loss For the cerebral cortex: - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: occipital pole (normal-to-mild atrophy on the right), occipital fusiform gyrus (normal-to-mild atrophy on the right), inf. occipital gyrus (normal-to-mild atrophy on the right) and middle occipital gyrus (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the frontal lobe - limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) - temporal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left), fusiform gyrus (normal-to-mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the left) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy both left/right), anterior insula (normal-to-mild atrophy on the left) and posterior insula (normal-to-mild atrophy on the left) - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy both left/right) For the ventricles: - external csf is free from enlargement or excessive growth - normal-to-mild enlargement of the 3rd ventricle - 4th ventricle appears structurally intact, with no evidence of enlargement - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - inf. lateral ventricle enlargement (severe on the left, mild on the right)	SD	We have the following subject's personal information: - The subject is a male of 74.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 3.0, corresponding to severe impairment. His standard CDR sum of boxes is 15.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 3.0 on language, corresponding to severe impairment.
FTLD_203664774_03476_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450825	On a T1-weighted brain MRI we observed: For the subcortical structures: - no pathological changes consistent with atrophy detected in the amygdala - no degenerative or atrophic changes noted in the pallidum - no pathological changes consistent with atrophy detected in the basal forebrain - the thalamus shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the hippocampus - no degenerative or atrophic changes noted in the ventral dc - normal-to-mild bilateral accumbens atrophy - the putamen shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the caudate For the ventricles: - external csf is free from enlargement or excessive growth - normal-to-mild enlargement of the 4th ventricle - the lateral ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the 3rd ventricle - normal-to-mild bilateral inf. lateral ventricle enlargement For the cerebral cortex: - no evidence of atrophy or degeneration in the parietal lobe - no evidence of atrophy or degeneration in the insular cortex - no observable atrophic alterations in the occipital lobe - frontal lobe maintains its normal morphology without atrophic features - temporal lobe appears structurally intact with no atrophic changes - limbic cortex maintains its normal morphology without atrophic features	PNFA	We have the following subject's personal information: - The subject is a male of 76.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203945852_01254_MR_Sagittal_MP-Rage_br_raw_20230124210916522_I10178544	On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the 4th ventricle - normal-to-mild enlargement of the external csf - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - lateral ventricle is free from enlargement or excessive growth For the cerebral cortex: - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the right) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy on the left) and posterior orbital gyrus (normal-to-mild atrophy on the right) - the occipital lobe shows no structural abnormalities indicative of atrophy - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left) and postcentral gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (mild atrophy on the left), temporal pole (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left) and transverse temporal gyrus (normal-to-mild atrophy on the right) For the subcortical structures: - no degenerative or atrophic changes noted in the putamen - ventral dc maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the hippocampus - accumbens atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral amygdala atrophy - no pathological changes consistent with atrophy detected in the caudate - basal forebrain presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the thalamus - no signs of atrophy detected in the pallidum	CN	We have the following subject's personal information: - The subject is a female of 57.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203965266_03666_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I11047655	On a T1-weighted brain MRI we observed: For the cerebral cortex: - occipital lobe remains normal, with no signs of tissue loss - the temporal lobe shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the parietal lobe - the frontal lobe shows no structural abnormalities indicative of atrophy - limbic cortex remains normal, with no signs of tissue loss - the insular cortex shows no structural abnormalities indicative of atrophy For the subcortical structures: - no observable atrophic alterations in the basal forebrain - putamen presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the caudate - no degenerative or atrophic changes noted in the thalamus - the ventral dc shows no structural abnormalities indicative of atrophy - hippocampus atrophy (normal-to-mild on the left, normal on the right) - pallidum appears structurally intact with no atrophic changes - accumbens remains normal, with no signs of tissue loss - amygdala appears structurally intact with no atrophic changes For the ventricles: - no enlargement observed in the inf. lateral ventricle - 4th ventricle is free from enlargement or excessive growth - no abnormal enlargement observed in the lateral ventricle - external csf appears structurally intact, with no evidence of enlargement - no observable enlargement or abnormal growth in the 3rd ventricle	CN	We have the following subject's personal information: - The subject is a male of 41.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203415533_01331_MR_Sagittal_MP-Rage_br_raw_20230124211214527_I10178561	On a T1-weighted brain MRI we observed: For the ventricles: - no abnormal enlargement observed in the 3rd ventricle - no enlargement observed in the external csf - no abnormal enlargement observed in the lateral ventricle - no abnormal enlargement observed in the 4th ventricle - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right) For the cerebral cortex: - no signs of atrophy detected in the occipital lobe - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the right) and transverse temporal gyrus (normal-to-mild atrophy on the right) - the limbic cortex shows no structural abnormalities indicative of atrophy - the parietal lobe shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the insular cortex - frontal lobe presents with a healthy appearance, free from atrophy For the subcortical structures: - no observable atrophic alterations in the ventral dc - no evidence of atrophy or degeneration in the hippocampus - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral caudate atrophy - no evidence of atrophy or degeneration in the thalamus - normal-to-mild bilateral putamen atrophy - accumbens appears structurally intact with no atrophic changes - amygdala maintains its normal morphology without atrophic features - pallidum appears structurally intact with no atrophic changes	CN	We have the following subject's personal information: - The subject is a female of 53.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203023197_01792_MR_Sagittal_MP-Rage_br_raw_20230209092223055_I10183099	On a T1-weighted brain MRI we observed: For the ventricles: - mild enlargement of the external csf - no enlargement observed in the 4th ventricle - inf. lateral ventricle enlargement (moderate on the left, mild on the right) - mild enlargement of the 3rd ventricle - mild bilateral lateral ventricle enlargement For the cerebral cortex: - no degenerative or atrophic changes noted in the occipital lobe - frontal lobe atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: middle frontal gyrus (moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), gyrus rectus (mild atrophy on the left), frontal pole (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the left) and anterior orbital gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy both left/right) - parietal lobe atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left), sup. parietal lobule (normal-to-mild atrophy on the left), postcentral gyrus medial segment (normal-to-mild atrophy on the left), precuneus (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the left) - no pathological changes consistent with atrophy detected in the temporal lobe - no observable atrophic alterations in the limbic cortex For the subcortical structures: - mild bilateral accumbens atrophy - ventral dc atrophy (normal-to-mild on the left, normal on the right) - caudate atrophy (moderate on the left, mild on the right) - pallidum atrophy (mild on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the amygdala - mild bilateral putamen atrophy - no observable atrophic alterations in the basal forebrain - hippocampus maintains its normal morphology without atrophic features - thalamus atrophy (mild on the left, normal-to-mild on the right)	SD	We have the following subject's personal information: - The subject is a female of 62.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203312212_02211_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10182937	On a T1-weighted brain MRI we observed: For the subcortical structures: - caudate maintains its normal morphology without atrophic features - the putamen shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the ventral dc - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - no evidence of atrophy or degeneration in the hippocampus - accumbens appears structurally intact with no atrophic changes - thalamus remains normal, with no signs of tissue loss - amygdala presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the pallidum For the ventricles: - normal-to-mild enlargement of the external csf - lateral ventricle maintains its normal volume without signs of enlargement - no signs of enlargement detected in the 4th ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the 3rd ventricle For the cerebral cortex: - occipital lobe presents with a healthy appearance, free from atrophy - limbic cortex appears structurally intact with no atrophic changes - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: parietal operculum (normal-to-mild atrophy both left/right) - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: medial frontal cortex (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy on the right) and precentral gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy both left/right), transverse temporal gyrus (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the right) - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right)	PNFA	We have the following subject's personal information: - The subject is a female of 81.0 years old. - She has 20.0 years of education (equivalent to doctorate) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203995947_01749_MR_Sagittal_MP-Rage_br_raw_20230206183603405_I10182577	On a T1-weighted brain MRI we observed: For the subcortical structures: - normal-to-mild bilateral thalamus atrophy - normal-to-mild bilateral putamen atrophy - no evidence of atrophy or degeneration in the basal forebrain - normal-to-mild bilateral ventral dc atrophy - normal-to-mild bilateral hippocampus atrophy - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral accumbens atrophy - amygdala maintains its normal morphology without atrophic features - caudate presents with a healthy appearance, free from atrophy For the cerebral cortex: - no pathological changes consistent with atrophy detected in the parietal lobe - no observable atrophic alterations in the temporal lobe - no evidence of atrophy or degeneration in the occipital lobe - no pathological changes consistent with atrophy detected in the insular cortex - no signs of atrophy detected in the frontal lobe - no pathological changes consistent with atrophy detected in the limbic cortex For the ventricles: - 3rd ventricle remains within normal size parameters, with no enlargement detected - no enlargement observed in the 4th ventricle - inf. lateral ventricle maintains its normal volume without signs of enlargement - no pathological changes consistent with enlargement noted in the external csf - lateral ventricle enlargement (normal-to-mild on the left, normal on the right)	CN	We have the following subject's personal information: - The subject is a female of 69.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203933841_02143_MR_Sagittal_MP-Rage_br_raw_20230124205938681_I10178482	On a T1-weighted brain MRI we observed: For the subcortical structures: - putamen atrophy (mild on the left, normal on the right) - amygdala atrophy (moderate on the left, normal on the right) - no evidence of atrophy or degeneration in the basal forebrain - thalamus appears structurally intact with no atrophic changes - the hippocampus shows no structural abnormalities indicative of atrophy - ventral dc presents with a healthy appearance, free from atrophy - caudate atrophy (mild on the left, normal on the right) - accumbens atrophy (moderate on the left, mild on the right) - pallidum appears structurally intact with no atrophic changes For the cerebral cortex: - no observable atrophic alterations in the occipital lobe - temporal lobe atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the left) - no evidence of atrophy or degeneration in the parietal lobe - insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (normal-to-mild atrophy both left/right) and central operculum (normal-to-mild atrophy both left/right) - frontal lobe atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: gyrus rectus (mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (mild atrophy both left/right), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy both left/right), supplementary motor cortex (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left) and anterior orbital gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (normal-to-mild atrophy on the left) For the ventricles: - no signs of enlargement detected in the 4th ventricle - normal-to-mild enlargement of the 3rd ventricle - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - inf. lateral ventricle enlargement (mild on the left, normal on the right) - normal-to-mild enlargement of the external csf	bvFTD	We have the following subject's personal information: - The subject is a female of 54.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203716415_01511_MR_Sagittal_MP-Rage_br_raw_20230124211554799_I10178582	On a T1-weighted brain MRI we observed: For the cerebral cortex: - occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: inf. occipital gyrus (normal-to-mild atrophy on the left), occipital pole (normal-to-mild atrophy both left/right), sup. occipital gyrus (normal-to-mild atrophy on the left) and cuneus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the right) and anterior cingulate gyrus (normal-to-mild atrophy on the right) - the temporal lobe shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the insular cortex - no evidence of atrophy or degeneration in the parietal lobe - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: medial orbital gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the left) and supplementary motor cortex (normal-to-mild atrophy on the left) For the ventricles: - lateral ventricle is free from enlargement or excessive growth - normal-to-mild enlargement of the external csf - no observable enlargement or abnormal growth in the inf. lateral ventricle - 3rd ventricle remains within normal size parameters, with no enlargement detected - 4th ventricle is free from enlargement or excessive growth For the subcortical structures: - no evidence of atrophy or degeneration in the putamen - pallidum atrophy (normal-to-mild on the left, normal on the right) - no pathological changes consistent with atrophy detected in the amygdala - no pathological changes consistent with atrophy detected in the basal forebrain - ventral dc appears structurally intact with no atrophic changes - normal-to-mild bilateral hippocampus atrophy - accumbens atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral caudate atrophy - no evidence of atrophy or degeneration in the thalamus	CN	We have the following subject's personal information: - The subject is a female of 60.0 years old. - She has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203175368_01867_MR_Sagittal_MP-Rage_br_raw_20230209093418458_I10183210	On a T1-weighted brain MRI we observed: For the subcortical structures: - amygdala atrophy (moderate on the left, mild on the right) - accumbens atrophy (mild on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the basal forebrain - pallidum atrophy (normal-to-mild on the left, normal on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - ventral dc remains normal, with no signs of tissue loss - caudate atrophy (mild on the left, normal on the right) - putamen atrophy (mild on the left, normal-to-mild on the right) - hippocampus atrophy (normal-to-mild on the left, normal on the right) For the cerebral cortex: - no signs of atrophy detected in the parietal lobe - temporal lobe atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (normal-to-mild atrophy both left/right) and middle temporal gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), entorhinal area (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - the occipital lobe shows no structural abnormalities indicative of atrophy - frontal lobe atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: gyrus rectus (mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy both left/right), lateral orbital gyrus (mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the left) and subcallosal area (normal-to-mild atrophy on the left) - insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), posterior insula (normal-to-mild atrophy on the left) and central operculum (normal-to-mild atrophy on the left) For the ventricles: - mild enlargement of the external csf - normal-to-mild bilateral lateral ventricle enlargement - normal-to-mild enlargement of the 4th ventricle - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right)	SD	We have the following subject's personal information: - The subject is a female of 57.0 years old. - She has 14.0 years of education We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203232136_02633_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177738	On a T1-weighted brain MRI we observed: For the subcortical structures: - basal forebrain atrophy (normal on the left, normal-to-mild on the right) - hippocampus atrophy (moderate on the left, normal-to-mild on the right) - no observable atrophic alterations in the thalamus - no pathological changes consistent with atrophy detected in the caudate - amygdala atrophy (severe on the left, moderate on the right) - putamen atrophy (mild on the left, normal on the right) - ventral dc remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the pallidum - accumbens atrophy (mild on the left, normal-to-mild on the right) For the ventricles: - no observable enlargement or abnormal growth in the lateral ventricle - moderate bilateral inf. lateral ventricle enlargement - 3rd ventricle appears structurally intact, with no evidence of enlargement - no signs of enlargement detected in the 4th ventricle - normal-to-mild enlargement of the external csf For the cerebral cortex: - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: medial frontal cortex (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left) and medial orbital gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the occipital lobe - mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), central operculum (mild atrophy on the left), frontal operculum (mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the right) - parietal lobe presents with a healthy appearance, free from atrophy - temporal lobe atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy both left/right), temporal pole (moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left), sup. temporal gyrus (normal-to-mild atrophy on the left) and transverse temporal gyrus (normal-to-mild atrophy on the right) - limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy both left/right), parahippocampal gyrus (mild atrophy both left/right), anterior cingulate gyrus (mild atrophy on the left), posterior cingulate gyrus (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left)	bvFTD	We have the following subject's personal information: - The subject is a male of 56.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 6.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203991421_03129_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176691	On a T1-weighted brain MRI we observed: For the cerebral cortex: - frontal lobe atrophy (moderate on the left, normal on the right), with focal volume loss observed in the following subregions: medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left), gyrus rectus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (mild atrophy on the left), middle frontal gyrus (mild atrophy on the left), sup. frontal gyrus medial segment (mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), frontal pole (mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left) and anterior orbital gyrus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the parietal lobe - temporal lobe atrophy (moderate on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left) and fusiform gyrus (normal-to-mild atrophy on the left) - no pathological changes consistent with atrophy detected in the occipital lobe - insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), central operculum (normal-to-mild atrophy both left/right), posterior insula (normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left) - limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), entorhinal area (mild atrophy on the left), parahippocampal gyrus (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) For the subcortical structures: - the basal forebrain shows no structural abnormalities indicative of atrophy - ventral dc remains normal, with no signs of tissue loss - amygdala atrophy (moderate on the left, mild on the right) - pallidum atrophy (normal-to-mild on the left, normal on the right) - hippocampus atrophy (normal-to-mild on the left, normal on the right) - putamen atrophy (mild on the left, normal on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - caudate atrophy (moderate on the left, normal-to-mild on the right) - mild bilateral accumbens atrophy For the ventricles: - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - no enlargement observed in the 4th ventricle - normal-to-mild enlargement of the 3rd ventricle - mild enlargement of the external csf - inf. lateral ventricle enlargement (mild on the left, normal on the right)	SD	We have the following subject's personal information: - The subject is a male of 56.0 years old. - He has 18.0 years of education (equivalent to master’s degree) We have the following results on the Neuropsychological Test Battery: - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. His standard CDR sum of boxes is 9.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.

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