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NIFD_1_S_0208_MR_T1_mprage_short_S21_DIS3D__br_raw_20170817123327650_44_S597915_I891422 | On a T1-weighted brain MRI we observed:
For the ventricles:
- severe bilateral lateral ventricle enlargement
- moderate enlargement of the 3rd ventricle
- severe enlargement of the external csf
- severe enlargement of the inf. lateral ventricle
- the 4th ventricle shows no structural abnormalities indicative of enlargement
For the subcortical structures:
- no evidence of atrophy or degeneration in the ventral dc
- the basal forebrain shows no structural abnormalities indicative of atrophy
- severe atrophy of the thalamus
- mild atrophy of the hippocampus
- severe bilateral accumbens atrophy
- severe bilateral amygdala atrophy
- severe bilateral pallidum atrophy
- severe bilateral putamen atrophy
- severe bilateral caudate atrophy
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (between normal and mild), opercular inf. frontal gyrus (severe), orbital inf. frontal gyrus (mild), middle frontal gyrus (between moderate and severe), anterior orbital gyrus (severe), lateral orbital gyrus (mild), medial orbital gyrus (moderate), posterior orbital gyrus (severe), precentral gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (between normal and mild) and supplementary motor cortex (mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between mild and moderate)
- mild atrophy of the occipital lobe, with focal volume loss observed in the following subregions: cuneus (mild), inf. occipital gyrus (between moderate and severe), occipital pole (mild) and sup. occipital gyrus (between normal and mild)
- severe atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (between moderate and severe), posterior insula (mild), central operculum (mild) and frontal operculum (between mild and moderate)
- moderate atrophy of the temporal lobe, with focal volume loss observed in the following subregions: transverse temporal gyrus (between normal and mild), temporal pole (severe) and fusiform gyrus (mild)
- between moderate and severe atrophy of the parietal lobe, with focal volume loss observed in the following subregions: angular gyrus (mild), precuneus (mild) and supramarginal gyrus (between mild and moderate) | BV |
ADNI_019_S_4252_MR_MPRAGE_br_raw_20110929160944680_32_S123970_I258947 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- caudate remains normal, with no signs of tissue loss
- between normal and mild atrophy of the hippocampus
- amygdala appears structurally intact with no atrophic changes
- between normal and mild atrophy of the putamen
- the thalamus shows no structural abnormalities indicative of atrophy
- ventral dc maintains its normal morphology without atrophic features
- no signs of atrophy detected in the basal forebrain
- between normal and mild right atrophy of the accumbens
- pallidum appears structurally intact with no atrophic changes
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (between normal and mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between mild and moderate)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior insula (between normal and mild) and frontal operculum (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (between normal and mild)
- no degenerative or atrophic changes noted in the parietal lobe
For the ventricles:
- mild enlargement of the inf. lateral ventricle
- no abnormal enlargement observed in the 3rd ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
- between normal and mild enlargement of the lateral ventricle
- no pathological changes consistent with enlargement noted in the external csf | AD |
NIFD_1_S_0277_MR_t1_mprage__br_raw_20160903201332611_41_S496668_I772969 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- thalamus appears structurally intact with no atrophic changes
- caudate maintains its normal morphology without atrophic features
- amygdala appears structurally intact with no atrophic changes
- hippocampus presents with a healthy appearance, free from atrophy
- basal forebrain maintains its normal morphology without atrophic features
- ventral dc maintains its normal morphology without atrophic features
- the pallidum shows no structural abnormalities indicative of atrophy
- putamen presents with a healthy appearance, free from atrophy
- between normal and mild left atrophy of the accumbens
For the cerebral cortex:
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in transverse temporal gyrus (between mild and moderate)
- insular cortex remains normal, with no signs of tissue loss
- no signs of atrophy detected in the parietal lobe
- occipital lobe remains normal, with no signs of tissue loss
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between normal and mild)
- mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (mild), middle frontal gyrus (mild), subcallosal area (between normal and mild) and supplementary motor cortex (mild)
For the ventricles:
- no abnormal enlargement observed in the 4th ventricle
- no abnormal enlargement observed in the 3rd ventricle
- external csf appears structurally intact, with no evidence of enlargement
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- lateral ventricle appears structurally intact, with no evidence of enlargement | CN |
ADNI_016_S_4353_MR_Accelerated_SAG_IR-SPGR__br_raw_20111122093825556_165_S130365_I267942 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- between mild and moderate bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (mild) and temporal pole (between normal and mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (between normal and mild) and sup. occipital gyrus (between normal and mild)
- moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: precuneus (moderate), sup. parietal lobule (between normal and mild) and supramarginal gyrus (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal operculum (between normal and mild)
For the subcortical structures:
- mild bilateral accumbens atrophy
- no observable atrophic alterations in the ventral dc
- putamen appears structurally intact with no atrophic changes
- mild atrophy of the amygdala
- no signs of atrophy detected in the pallidum
- no pathological changes consistent with atrophy detected in the basal forebrain
- hippocampus presents with a healthy appearance, free from atrophy
- thalamus remains normal, with no signs of tissue loss
- between normal and mild bilateral caudate atrophy
For the ventricles:
- moderate enlargement of the 3rd ventricle
- mild enlargement of the external csf
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- no abnormal enlargement observed in the 4th ventricle
- between mild and moderate bilateral lateral ventricle enlargement | AD |
NIFD_1_S_0168_MR_T1_mprage_S3_DIS3D_br_raw_20140831174246544_25_S229023_I441337 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- between normal and mild atrophy of the occipital lobe, with focal volume loss observed in the following subregions: calcarine cortex (between normal and mild), middle occipital gyrus (mild) and sup. occipital gyrus (between normal and mild)
- no pathological changes consistent with atrophy detected in the insular cortex
- no pathological changes consistent with atrophy detected in the parietal lobe
- limbic cortex presents with a healthy appearance, free from atrophy
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in transverse temporal gyrus (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. frontal gyrus (between normal and mild)
For the subcortical structures:
- no degenerative or atrophic changes noted in the thalamus
- no evidence of atrophy or degeneration in the basal forebrain
- caudate remains normal, with no signs of tissue loss
- no observable atrophic alterations in the accumbens
- no observable atrophic alterations in the pallidum
- hippocampus maintains its normal morphology without atrophic features
- amygdala remains normal, with no signs of tissue loss
- ventral dc remains normal, with no signs of tissue loss
- putamen appears structurally intact with no atrophic changes
For the ventricles:
- no abnormal enlargement observed in the 3rd ventricle
- no signs of enlargement detected in the 4th ventricle
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- no observable enlargement or abnormal growth in the external csf
- lateral ventricle appears structurally intact, with no evidence of enlargement | CN |
NIFD_1_S_0038_MR_t1_mprage_S3_DIS3D_br_raw_20110418215853368_53_S104622_I228157 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no signs of enlargement detected in the external csf
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- 4th ventricle is free from enlargement or excessive growth
- lateral ventricle maintains its normal volume without signs of enlargement
- inf. lateral ventricle is free from enlargement or excessive growth
For the cerebral cortex:
- insular cortex appears structurally intact with no atrophic changes
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (between normal and mild)
- limbic cortex maintains its normal morphology without atrophic features
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lateral orbital gyrus (between normal and mild)
- occipital lobe presents with a healthy appearance, free from atrophy
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (mild) and precuneus (between normal and mild)
For the subcortical structures:
- mild atrophy of the basal forebrain
- between normal and mild left atrophy of the pallidum
- between normal and mild bilateral caudate atrophy
- mild bilateral accumbens atrophy
- no evidence of atrophy or degeneration in the hippocampus
- no degenerative or atrophic changes noted in the putamen
- no pathological changes consistent with atrophy detected in the amygdala
- between normal and mild atrophy of the thalamus
- mild bilateral ventral dc atrophy | PNFA |
ADNI_127_S_4749_MR_Accelerated_Sag_IR-SPGR__br_raw_20120531112453923_93_S152087_I307112 | On a T1-weighted brain MRI we observed:
For the ventricles:
- mild enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement
- mild enlargement of the 3rd ventricle
- between normal and mild left enlargement of the lateral ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
For the cerebral cortex:
- between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: precuneus (between mild and moderate)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parietal operculum (between normal and mild)
- no evidence of atrophy or degeneration in the frontal lobe
- between mild and moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (between normal and mild), posterior cingulate gyrus (between normal and mild) and anterior cingulate gyrus (mild)
- no signs of atrophy detected in the occipital lobe
- mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (between normal and mild), middle temporal gyrus (between moderate and severe) and planum temporale (between normal and mild)
For the subcortical structures:
- thalamus remains normal, with no signs of tissue loss
- basal forebrain presents with a healthy appearance, free from atrophy
- the ventral dc shows no structural abnormalities indicative of atrophy
- accumbens maintains its normal morphology without atrophic features
- between normal and mild left atrophy of the putamen
- between normal and mild right atrophy of the hippocampus
- between mild and moderate bilateral amygdala atrophy
- between mild and moderate bilateral caudate atrophy
- pallidum presents with a healthy appearance, free from atrophy | AD |
ADNI_136_S_4726_MR_MPRAGE_br_raw_20120606145610404_45_S153001_I308396 | On a T1-weighted brain MRI we observed:
For the ventricles:
- external csf appears structurally intact, with no evidence of enlargement
- no pathological changes consistent with enlargement noted in the lateral ventricle
- 3rd ventricle is free from enlargement or excessive growth
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected
For the subcortical structures:
- between normal and mild left atrophy of the pallidum
- between normal and mild right atrophy of the accumbens
- thalamus maintains its normal morphology without atrophic features
- putamen maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the ventral dc
- no evidence of atrophy or degeneration in the amygdala
- hippocampus remains normal, with no signs of tissue loss
- between normal and mild right atrophy of the basal forebrain
- mild bilateral caudate atrophy
For the cerebral cortex:
- no signs of atrophy detected in the limbic cortex
- no degenerative or atrophic changes noted in the frontal lobe
- no evidence of atrophy or degeneration in the temporal lobe
- no degenerative or atrophic changes noted in the occipital lobe
- no degenerative or atrophic changes noted in the parietal lobe
- insular cortex remains normal, with no signs of tissue loss | CN |
NIFD_1_S_0082_MR_T1_mprage_S3_DIS3D_br_raw_20120819183743033_55_S161525_I324784 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no enlargement observed in the 3rd ventricle
- moderate enlargement of the external csf
- no abnormal enlargement observed in the 4th ventricle
- between mild and moderate bilateral lateral ventricle enlargement
- moderate enlargement of the inf. lateral ventricle
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the parietal lobe
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (between normal and mild)
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (moderate)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle temporal gyrus (mild) and temporal pole (between mild and moderate)
- between mild and moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between moderate and severe)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (between moderate and severe), medial frontal cortex (moderate), middle frontal gyrus (severe), anterior orbital gyrus (between moderate and severe), lateral orbital gyrus (moderate), medial orbital gyrus (severe), posterior orbital gyrus (severe), sup. frontal gyrus medial segment (severe) and triangular inf. frontal gyrus (between mild and moderate)
For the subcortical structures:
- between normal and mild right atrophy of the thalamus
- moderate bilateral caudate atrophy
- severe bilateral accumbens atrophy
- basal forebrain appears structurally intact with no atrophic changes
- between normal and mild right atrophy of the pallidum
- moderate bilateral putamen atrophy
- no signs of atrophy detected in the ventral dc
- between normal and mild atrophy of the hippocampus
- between normal and mild atrophy of the amygdala | BV |
ADNI_094_S_4459_MR_Accelerated_SAG_IR-SPGR__br_raw_20120222110144176_106_S140152_I283439 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no signs of atrophy detected in the thalamus
- ventral dc remains normal, with no signs of tissue loss
- between normal and mild atrophy of the caudate
- no evidence of atrophy or degeneration in the basal forebrain
- between mild and moderate bilateral putamen atrophy
- the accumbens shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the amygdala
- mild bilateral pallidum atrophy
- no signs of atrophy detected in the hippocampus
For the cerebral cortex:
- frontal lobe presents with a healthy appearance, free from atrophy
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in supramarginal gyrus (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. occipital gyrus (mild)
- the limbic cortex shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the insular cortex
- no pathological changes consistent with atrophy detected in the temporal lobe
For the ventricles:
- 4th ventricle appears structurally intact, with no evidence of enlargement
- no pathological changes consistent with enlargement noted in the external csf
- no enlargement observed in the lateral ventricle
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- 3rd ventricle remains within normal size parameters, with no enlargement detected | CN |
NIFD_1_S_0002_MR_t1_mprage_short_S11_DIS3D__br_raw_20110719203216691_65_S115356_I245709 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no evidence of atrophy or degeneration in the ventral dc
- severe bilateral accumbens atrophy
- severe bilateral hippocampus atrophy
- severe bilateral caudate atrophy
- severe bilateral putamen atrophy
- severe bilateral amygdala atrophy
- thalamus remains normal, with no signs of tissue loss
- the pallidum shows no structural abnormalities indicative of atrophy
- basal forebrain remains normal, with no signs of tissue loss
For the cerebral cortex:
- parietal lobe presents with a healthy appearance, free from atrophy
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (moderate), gyrus rectus (severe), opercular inf. frontal gyrus (between moderate and severe), orbital inf. frontal gyrus (between mild and moderate), medial frontal cortex (severe), middle frontal gyrus (severe), anterior orbital gyrus (moderate), lateral orbital gyrus (severe), medial orbital gyrus (moderate), posterior orbital gyrus (severe), sup. frontal gyrus (between mild and moderate), sup. frontal gyrus medial segment (severe) and triangular inf. frontal gyrus (mild)
- no observable atrophic alterations in the occipital lobe
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (mild), inf. temporal gyrus (severe), middle temporal gyrus (severe) and temporal pole (severe)
- between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (between normal and mild)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between moderate and severe) and anterior cingulate gyrus (severe)
For the ventricles:
- severe enlargement of the external csf
- between normal and mild enlargement of the lateral ventricle
- severe bilateral inf. lateral ventricle enlargement
- no abnormal enlargement observed in the 4th ventricle
- moderate enlargement of the 3rd ventricle | BV |
ADNI_016_S_4887_MR_Accelerated_SAG_IR-SPGR__br_raw_20120822093912566_54_S162209_I325642 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no degenerative or atrophic changes noted in the occipital lobe
- the frontal lobe shows no structural abnormalities indicative of atrophy
- the insular cortex shows no structural abnormalities indicative of atrophy
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (between normal and mild)
- parietal lobe maintains its normal morphology without atrophic features
- no observable atrophic alterations in the limbic cortex
For the ventricles:
- between normal and mild enlargement of the inf. lateral ventricle
- no signs of enlargement detected in the 3rd ventricle
- no pathological changes consistent with enlargement noted in the lateral ventricle
- external csf is free from enlargement or excessive growth
- no signs of enlargement detected in the 4th ventricle
For the subcortical structures:
- no observable atrophic alterations in the caudate
- no signs of atrophy detected in the basal forebrain
- no evidence of atrophy or degeneration in the pallidum
- mild bilateral amygdala atrophy
- no pathological changes consistent with atrophy detected in the ventral dc
- no degenerative or atrophic changes noted in the accumbens
- mild bilateral hippocampus atrophy
- no pathological changes consistent with atrophy detected in the putamen
- no degenerative or atrophic changes noted in the thalamus | AD |
ADNI_018_S_4733_MR_MPRAGE_br_raw_20120523122532411_63_S151381_I306069 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- between normal and mild left atrophy of the pallidum
- mild atrophy of the amygdala
- no observable atrophic alterations in the accumbens
- no degenerative or atrophic changes noted in the caudate
- putamen presents with a healthy appearance, free from atrophy
- hippocampus remains normal, with no signs of tissue loss
- ventral dc maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the thalamus
- basal forebrain appears structurally intact with no atrophic changes
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (between normal and mild)
- no observable atrophic alterations in the parietal lobe
- no degenerative or atrophic changes noted in the temporal lobe
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (mild), anterior cingulate gyrus (between mild and moderate), middle cingulate gyrus (mild) and parahippocampal gyrus (moderate)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between mild and moderate)
- no degenerative or atrophic changes noted in the insular cortex
For the ventricles:
- external csf is free from enlargement or excessive growth
- lateral ventricle remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- no signs of enlargement detected in the 4th ventricle
- no enlargement observed in the 3rd ventricle | AD |
NIFD_2_S_0020_MR_MT1__GradWarp__N3m_Br_20130114173807523_S160394_I355048 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- parietal lobe presents with a healthy appearance, free from atrophy
- the temporal lobe shows no structural abnormalities indicative of atrophy
- limbic cortex remains normal, with no signs of tissue loss
- no signs of atrophy detected in the insular cortex
- between mild and moderate bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: lingual gyrus (between moderate and severe) and inf. occipital gyrus (between mild and moderate)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior orbital gyrus (between normal and mild) and sup. frontal gyrus (between normal and mild)
For the ventricles:
- 4th ventricle is free from enlargement or excessive growth
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- 3rd ventricle is free from enlargement or excessive growth
- no signs of enlargement detected in the lateral ventricle
- no enlargement observed in the external csf
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the hippocampus
- no signs of atrophy detected in the thalamus
- ventral dc remains normal, with no signs of tissue loss
- no observable atrophic alterations in the amygdala
- putamen presents with a healthy appearance, free from atrophy
- accumbens remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the basal forebrain
- no signs of atrophy detected in the pallidum
- no evidence of atrophy or degeneration in the caudate | CN |
NIFD_1_S_0312_MR_t1_mprage_S3_DIS3D_br_raw_20160909141655212_27_S498027_I774594 | On a T1-weighted brain MRI we observed:
For the ventricles:
- lateral ventricle remains within normal size parameters, with no enlargement detected
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- between mild and moderate enlargement of the external csf
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- no enlargement observed in the 4th ventricle
For the subcortical structures:
- caudate appears structurally intact with no atrophic changes
- amygdala presents with a healthy appearance, free from atrophy
- the putamen shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the basal forebrain
- no evidence of atrophy or degeneration in the ventral dc
- pallidum maintains its normal morphology without atrophic features
- between normal and mild atrophy of the accumbens
- hippocampus remains normal, with no signs of tissue loss
- no signs of atrophy detected in the thalamus
For the cerebral cortex:
- mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: orbital inf. frontal gyrus (mild), medial frontal cortex (mild), middle frontal gyrus (between normal and mild), anterior orbital gyrus (mild) and supplementary motor cortex (between moderate and severe)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (between normal and mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (between normal and mild)
- between mild and moderate bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild), planum polare (between normal and mild), planum temporale (between normal and mild), sup. temporal gyrus (mild) and temporal pole (mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (mild) and frontal operculum (between normal and mild)
- no observable atrophic alterations in the parietal lobe | CN |
ADNI_053_S_5070_MR_MPRAGE_br_raw_20130201111516375_67_S181275_I357474 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- between normal and mild atrophy of the putamen
- no degenerative or atrophic changes noted in the pallidum
- no pathological changes consistent with atrophy detected in the basal forebrain
- accumbens maintains its normal morphology without atrophic features
- no observable atrophic alterations in the thalamus
- no pathological changes consistent with atrophy detected in the amygdala
- hippocampus presents with a healthy appearance, free from atrophy
- ventral dc remains normal, with no signs of tissue loss
- mild left atrophy of the caudate
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (mild) and posterior orbital gyrus (mild)
- between mild and moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), precuneus (mild) and supramarginal gyrus (between normal and mild)
- between normal and mild atrophy of the insular cortex
- mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (between mild and moderate) and middle temporal gyrus (mild)
- mild atrophy of the occipital lobe, with focal volume loss observed in the following subregions: sup. occipital gyrus (mild), occipital pole (between normal and mild), occipital fusiform gyrus (between normal and mild) and middle occipital gyrus (between normal and mild)
- mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (between normal and mild) and middle cingulate gyrus (between normal and mild)
For the ventricles:
- no signs of enlargement detected in the external csf
- mild enlargement of the 3rd ventricle
- no signs of enlargement detected in the 4th ventricle
- severe bilateral lateral ventricle enlargement
- between normal and mild enlargement of the inf. lateral ventricle | AD |
NIFD_1_S_0197_MR_T1_mprage_S3_DIS3D_br_raw_20140901101140122_64_S229485_I441856 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum polare (between normal and mild) and middle temporal gyrus (mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precuneus (moderate) and supramarginal gyrus (mild)
- no signs of atrophy detected in the limbic cortex
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal operculum (between normal and mild) and parietal operculum (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in orbital inf. frontal gyrus (between normal and mild), medial frontal cortex (between normal and mild), middle frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (mild)
- between normal and mild atrophy of the occipital lobe
For the ventricles:
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- no abnormal enlargement observed in the inf. lateral ventricle
- no abnormal enlargement observed in the lateral ventricle
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- between mild and moderate enlargement of the external csf
For the subcortical structures:
- no signs of atrophy detected in the basal forebrain
- putamen remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the pallidum
- no pathological changes consistent with atrophy detected in the hippocampus
- no degenerative or atrophic changes noted in the thalamus
- no degenerative or atrophic changes noted in the ventral dc
- the caudate shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the amygdala
- accumbens remains normal, with no signs of tissue loss | CN |
ADNI_068_S_4968_MR_MPRAGE_br_raw_20130219083940125_109_S182627_I360599 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- between normal and mild left atrophy of the accumbens
- the basal forebrain shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the hippocampus
- no pathological changes consistent with atrophy detected in the pallidum
- no pathological changes consistent with atrophy detected in the thalamus
- caudate maintains its normal morphology without atrophic features
- putamen maintains its normal morphology without atrophic features
- no observable atrophic alterations in the amygdala
- no observable atrophic alterations in the ventral dc
For the ventricles:
- between normal and mild enlargement of the 3rd ventricle
- between moderate and severe bilateral inf. lateral ventricle enlargement
- no enlargement observed in the 4th ventricle
- the external csf shows no structural abnormalities indicative of enlargement
- between normal and mild enlargement of the lateral ventricle
For the cerebral cortex:
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal operculum (between normal and mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parahippocampal gyrus (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between mild and moderate) and occipital pole (between normal and mild)
- between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: triangular inf. frontal gyrus (between normal and mild) and sup. frontal gyrus (mild)
- no evidence of atrophy or degeneration in the parietal lobe
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (between normal and mild) | AD |
NIFD_1_S_0193_MR_T1_mprage_S3_DIS3D_br_raw_20170816170450108_27_S596839_I889944 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the insular cortex shows no structural abnormalities indicative of atrophy
- frontal lobe presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the parietal lobe
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in transverse temporal gyrus (between normal and mild)
- limbic cortex maintains its normal morphology without atrophic features
For the subcortical structures:
- no degenerative or atrophic changes noted in the basal forebrain
- no signs of atrophy detected in the amygdala
- pallidum maintains its normal morphology without atrophic features
- hippocampus maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the accumbens
- no signs of atrophy detected in the ventral dc
- the caudate shows no structural abnormalities indicative of atrophy
- putamen remains normal, with no signs of tissue loss
- thalamus appears structurally intact with no atrophic changes
For the ventricles:
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- no abnormal enlargement observed in the external csf
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no observable enlargement or abnormal growth in the 4th ventricle | CN |
NIFD_1_S_0293_MR_t1_mprage__br_raw_20160903215513127_81_S496861_I773193 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- between mild and moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild), posterior cingulate gyrus (moderate) and parahippocampal gyrus (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus medial segment (between normal and mild) and precuneus (between normal and mild)
- insular cortex presents with a healthy appearance, free from atrophy
- the occipital lobe shows no structural abnormalities indicative of atrophy
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior orbital gyrus (between normal and mild), subcallosal area (between normal and mild) and sup. frontal gyrus (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in temporal pole (between normal and mild)
For the ventricles:
- no signs of enlargement detected in the 3rd ventricle
- the external csf shows no structural abnormalities indicative of enlargement
- no signs of enlargement detected in the lateral ventricle
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
- 4th ventricle is free from enlargement or excessive growth
For the subcortical structures:
- the accumbens shows no structural abnormalities indicative of atrophy
- basal forebrain remains normal, with no signs of tissue loss
- hippocampus presents with a healthy appearance, free from atrophy
- between normal and mild left atrophy of the thalamus
- no evidence of atrophy or degeneration in the amygdala
- the pallidum shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the caudate
- ventral dc appears structurally intact with no atrophic changes
- putamen appears structurally intact with no atrophic changes | CN |
ADNI_018_S_4349_MR_MPRAGE_br_raw_20111115135850836_96_S129394_I266625 | On a T1-weighted brain MRI we observed:
For the ventricles:
- external csf maintains its normal volume without signs of enlargement
- no signs of enlargement detected in the 4th ventricle
- 3rd ventricle is free from enlargement or excessive growth
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- lateral ventricle is free from enlargement or excessive growth
For the cerebral cortex:
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parietal operculum (between normal and mild)
- temporal lobe maintains its normal morphology without atrophic features
- the parietal lobe shows no structural abnormalities indicative of atrophy
- limbic cortex maintains its normal morphology without atrophic features
- no observable atrophic alterations in the occipital lobe
- no pathological changes consistent with atrophy detected in the frontal lobe
For the subcortical structures:
- no observable atrophic alterations in the amygdala
- no pathological changes consistent with atrophy detected in the thalamus
- no degenerative or atrophic changes noted in the basal forebrain
- hippocampus appears structurally intact with no atrophic changes
- between normal and mild atrophy of the ventral dc
- no degenerative or atrophic changes noted in the caudate
- no pathological changes consistent with atrophy detected in the accumbens
- the putamen shows no structural abnormalities indicative of atrophy
- pallidum appears structurally intact with no atrophic changes | CN |
NIFD_2_S_0016_MR_MT1__GradWarp__N3m_Br_20130131161214414_S180124_I357405 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe) and entorhinal area (mild)
- moderate atrophy of the frontal lobe, with focal volume loss observed in the following subregions: gyrus rectus (severe), medial frontal cortex (between mild and moderate), anterior orbital gyrus (mild), lateral orbital gyrus (between mild and moderate), medial orbital gyrus (severe), posterior orbital gyrus (moderate), precentral gyrus medial segment (between normal and mild), sup. frontal gyrus medial segment (moderate), middle frontal gyrus (between normal and mild) and sup. frontal gyrus (between normal and mild)
- mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (between normal and mild) and transverse temporal gyrus (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (between normal and mild)
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (between normal and mild)
- parietal lobe appears structurally intact with no atrophic changes
For the ventricles:
- mild bilateral lateral ventricle enlargement
- moderate enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement
- no pathological changes consistent with enlargement noted in the 4th ventricle
- moderate enlargement of the external csf
For the subcortical structures:
- severe bilateral caudate atrophy
- between moderate and severe bilateral pallidum atrophy
- between normal and mild atrophy of the thalamus
- between mild and moderate atrophy of the hippocampus
- severe bilateral amygdala atrophy
- between normal and mild left atrophy of the ventral dc
- severe bilateral putamen atrophy
- basal forebrain remains normal, with no signs of tissue loss
- severe bilateral accumbens atrophy | BV |
NIFD_1_S_0083_MR_T1_mprage_S3_DIS3D_br_raw_20120819151737775_85_S161445_I324693 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus medial segment (between normal and mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal operculum (between normal and mild)
- no evidence of atrophy or degeneration in the temporal lobe
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. parietal lobule (between mild and moderate)
- mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (between normal and mild), cuneus (mild), inf. occipital gyrus (between mild and moderate) and sup. occipital gyrus (between mild and moderate)
- the limbic cortex shows no structural abnormalities indicative of atrophy
For the ventricles:
- external csf remains within normal size parameters, with no enlargement detected
- lateral ventricle maintains its normal volume without signs of enlargement
- no observable enlargement or abnormal growth in the 3rd ventricle
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no observable enlargement or abnormal growth in the 4th ventricle
For the subcortical structures:
- accumbens remains normal, with no signs of tissue loss
- between normal and mild bilateral ventral dc atrophy
- no observable atrophic alterations in the pallidum
- the thalamus shows no structural abnormalities indicative of atrophy
- caudate maintains its normal morphology without atrophic features
- the basal forebrain shows no structural abnormalities indicative of atrophy
- amygdala maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the hippocampus
- no pathological changes consistent with atrophy detected in the putamen | CN |
NIFD_1_S_0188_MR_T1_mprage_S3_DIS3D_br_raw_20140831185220381_16_S229114_I441440 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no signs of enlargement detected in the 4th ventricle
- between moderate and severe bilateral lateral ventricle enlargement
- moderate enlargement of the 3rd ventricle
- between mild and moderate enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement
For the cerebral cortex:
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild), central operculum (mild) and frontal operculum (between mild and moderate)
- no evidence of atrophy or degeneration in the occipital lobe
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe) and posterior cingulate gyrus (mild)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (moderate), opercular inf. frontal gyrus (between moderate and severe), orbital inf. frontal gyrus (between mild and moderate), triangular inf. frontal gyrus (mild), medial frontal cortex (severe), middle frontal gyrus (severe), lateral orbital gyrus (between normal and mild), medial orbital gyrus (between mild and moderate), posterior orbital gyrus (mild), sup. frontal gyrus medial segment (between moderate and severe) and anterior orbital gyrus (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in temporal pole (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (between normal and mild)
For the subcortical structures:
- amygdala maintains its normal morphology without atrophic features
- mild left atrophy of the thalamus
- moderate bilateral accumbens atrophy
- no degenerative or atrophic changes noted in the ventral dc
- severe bilateral caudate atrophy
- severe bilateral putamen atrophy
- no evidence of atrophy or degeneration in the hippocampus
- between normal and mild atrophy of the pallidum
- basal forebrain remains normal, with no signs of tissue loss | BV |
ADNI_116_S_4732_MR_MPRAGE_br_raw_20120601084840632_98_S152434_I307561 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- frontal lobe presents with a healthy appearance, free from atrophy
- the insular cortex shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the limbic cortex
- temporal lobe maintains its normal morphology without atrophic features
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (mild) and middle occipital gyrus (between normal and mild)
- no degenerative or atrophic changes noted in the parietal lobe
For the subcortical structures:
- accumbens presents with a healthy appearance, free from atrophy
- between normal and mild atrophy of the hippocampus
- between normal and mild bilateral thalamus atrophy
- no observable atrophic alterations in the caudate
- no evidence of atrophy or degeneration in the amygdala
- moderate bilateral pallidum atrophy
- between moderate and severe bilateral putamen atrophy
- between mild and moderate bilateral ventral dc atrophy
- no observable atrophic alterations in the basal forebrain
For the ventricles:
- between normal and mild enlargement of the lateral ventricle
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- no enlargement observed in the inf. lateral ventricle
- the external csf shows no structural abnormalities indicative of enlargement
- no abnormal enlargement observed in the 4th ventricle | AD |
NIFD_1_S_0022_MR_t1_mprage_S3_DIS3D_br_raw_20110207052850292_87_S99089_I216037 | On a T1-weighted brain MRI we observed:
For the ventricles:
- lateral ventricle appears structurally intact, with no evidence of enlargement
- no signs of enlargement detected in the 4th ventricle
- severe enlargement of the inf. lateral ventricle
- severe enlargement of the external csf
- no pathological changes consistent with enlargement noted in the 3rd ventricle
For the subcortical structures:
- severe bilateral accumbens atrophy
- moderate bilateral caudate atrophy
- mild atrophy of the hippocampus
- no evidence of atrophy or degeneration in the pallidum
- no evidence of atrophy or degeneration in the basal forebrain
- no pathological changes consistent with atrophy detected in the thalamus
- mild atrophy of the putamen
- severe bilateral amygdala atrophy
- ventral dc appears structurally intact with no atrophic changes
For the cerebral cortex:
- occipital lobe presents with a healthy appearance, free from atrophy
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (moderate), central operculum (between normal and mild) and frontal operculum (mild)
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (severe), anterior cingulate gyrus (moderate) and parahippocampal gyrus (mild)
- between moderate and severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (moderate), gyrus rectus (between normal and mild), opercular inf. frontal gyrus (between normal and mild), triangular inf. frontal gyrus (between mild and moderate), medial frontal cortex (between mild and moderate), lateral orbital gyrus (between mild and moderate), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus medial segment (severe) and orbital inf. frontal gyrus (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (between normal and mild)
- severe atrophy of the temporal lobe, with focal volume loss observed in the following subregions: fusiform gyrus (mild), middle temporal gyrus (mild), temporal pole (between moderate and severe) and planum polare (mild) | SV |
NIFD_1_S_0059_MR_t1_mprage_S3_DIS3D_br_raw_20111019183350018_67_S125844_I261661 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- parietal lobe maintains its normal morphology without atrophic features
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (between mild and moderate), gyrus rectus (severe), opercular inf. frontal gyrus (moderate), triangular inf. frontal gyrus (between mild and moderate), medial frontal cortex (between moderate and severe), middle frontal gyrus (moderate), anterior orbital gyrus (between moderate and severe), medial orbital gyrus (between mild and moderate), posterior orbital gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (between moderate and severe) and supplementary motor cortex (mild)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate), anterior cingulate gyrus (severe) and parahippocampal gyrus (between mild and moderate)
- occipital lobe remains normal, with no signs of tissue loss
- between normal and mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: temporal pole (severe)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between mild and moderate) and frontal operculum (severe)
For the ventricles:
- severe enlargement of the external csf
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- mild enlargement of the 3rd ventricle
- no enlargement observed in the 4th ventricle
- moderate bilateral lateral ventricle enlargement
For the subcortical structures:
- basal forebrain appears structurally intact with no atrophic changes
- thalamus maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the ventral dc
- severe bilateral caudate atrophy
- mild bilateral hippocampus atrophy
- severe bilateral amygdala atrophy
- severe bilateral putamen atrophy
- between moderate and severe bilateral pallidum atrophy
- severe bilateral accumbens atrophy | BV |
NIFD_1_S_0227_MR_T1_mprage_S3_DIS3D_br_raw_20170817121358717_126_S597834_I891319 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no degenerative or atrophic changes noted in the thalamus
- the caudate shows no structural abnormalities indicative of atrophy
- accumbens remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the pallidum
- no pathological changes consistent with atrophy detected in the hippocampus
- no signs of atrophy detected in the amygdala
- putamen presents with a healthy appearance, free from atrophy
- ventral dc remains normal, with no signs of tissue loss
- the basal forebrain shows no structural abnormalities indicative of atrophy
For the ventricles:
- no signs of enlargement detected in the lateral ventricle
- no abnormal enlargement observed in the external csf
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
For the cerebral cortex:
- no degenerative or atrophic changes noted in the frontal lobe
- no signs of atrophy detected in the temporal lobe
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus (between normal and mild) and precuneus (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. occipital gyrus (mild) and cuneus (between normal and mild)
- no signs of atrophy detected in the limbic cortex
- no degenerative or atrophic changes noted in the insular cortex | CN |
NIFD_1_S_0147_MR_T1_mprage_S3_DIS3D_br_raw_20140612224636364_53_S222067_I430635 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild), medial frontal cortex (mild), middle frontal gyrus (moderate), medial orbital gyrus (between normal and mild) and precentral gyrus (between normal and mild)
- no degenerative or atrophic changes noted in the parietal lobe
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (mild)
- no signs of atrophy detected in the occipital lobe
- insular cortex appears structurally intact with no atrophic changes
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (between normal and mild)
For the subcortical structures:
- no observable atrophic alterations in the basal forebrain
- the thalamus shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the hippocampus
- between normal and mild atrophy of the caudate
- putamen maintains its normal morphology without atrophic features
- amygdala appears structurally intact with no atrophic changes
- between normal and mild atrophy of the pallidum
- between mild and moderate bilateral accumbens atrophy
- the ventral dc shows no structural abnormalities indicative of atrophy
For the ventricles:
- no signs of enlargement detected in the 3rd ventricle
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- no observable enlargement or abnormal growth in the external csf
- lateral ventricle appears structurally intact, with no evidence of enlargement
- inf. lateral ventricle is free from enlargement or excessive growth | PNFA |
NIFD_1_S_0065_MR_t1_mprage_S3_DIS3D_br_raw_20111209104413296_6_S132363_I270815 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- between normal and mild atrophy of the amygdala
- basal forebrain remains normal, with no signs of tissue loss
- between mild and moderate bilateral accumbens atrophy
- between normal and mild atrophy of the putamen
- ventral dc remains normal, with no signs of tissue loss
- hippocampus maintains its normal morphology without atrophic features
- moderate bilateral caudate atrophy
- between normal and mild left atrophy of the thalamus
- mild atrophy of the pallidum
For the cerebral cortex:
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus (between normal and mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild) and middle cingulate gyrus (mild)
- occipital lobe maintains its normal morphology without atrophic features
- between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (between mild and moderate) and parietal operculum (between mild and moderate)
- between mild and moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (between normal and mild) and middle frontal gyrus (severe)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (moderate), sup. temporal gyrus (mild) and transverse temporal gyrus (mild)
For the ventricles:
- 4th ventricle maintains its normal volume without signs of enlargement
- severe bilateral inf. lateral ventricle enlargement
- between mild and moderate enlargement of the external csf
- mild bilateral lateral ventricle enlargement
- severe enlargement of the 3rd ventricle | PNFA |
NIFD_1_S_0303_MR_t1_mprage__br_raw_20160903224906478_34_S496940_I773286 | On a T1-weighted brain MRI we observed:
For the ventricles:
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- no enlargement observed in the external csf
- no signs of enlargement detected in the 3rd ventricle
- lateral ventricle remains within normal size parameters, with no enlargement detected
- no abnormal enlargement observed in the 4th ventricle
For the subcortical structures:
- amygdala appears structurally intact with no atrophic changes
- ventral dc remains normal, with no signs of tissue loss
- mild bilateral thalamus atrophy
- the pallidum shows no structural abnormalities indicative of atrophy
- no pathological changes consistent with atrophy detected in the putamen
- basal forebrain remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the accumbens
- hippocampus maintains its normal morphology without atrophic features
- caudate maintains its normal morphology without atrophic features
For the cerebral cortex:
- insular cortex presents with a healthy appearance, free from atrophy
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle occipital gyrus (between normal and mild)
- the temporal lobe shows no structural abnormalities indicative of atrophy
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parahippocampal gyrus (between normal and mild)
- between normal and mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (between normal and mild), middle frontal gyrus (between normal and mild), precentral gyrus medial segment (mild) and sup. frontal gyrus medial segment (between mild and moderate)
- the parietal lobe shows no structural abnormalities indicative of atrophy | CN |
NIFD_1_S_0128_MR_T1_mprage_S5_DIS3D_br_raw_20170817092725939_46_S597144_I890396 | On a T1-weighted brain MRI we observed:
For the ventricles:
- between moderate and severe enlargement of the external csf
- mild enlargement of the lateral ventricle
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected
- severe bilateral inf. lateral ventricle enlargement
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (mild), opercular inf. frontal gyrus (between normal and mild), middle frontal gyrus (severe), sup. frontal gyrus (moderate) and sup. frontal gyrus medial segment (between mild and moderate)
- no signs of atrophy detected in the parietal lobe
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. occipital gyrus (mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (between normal and mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (mild)
- moderate atrophy of the temporal lobe, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild), inf. temporal gyrus (between mild and moderate), middle temporal gyrus (between normal and mild), sup. temporal gyrus (between normal and mild) and temporal pole (between normal and mild)
For the subcortical structures:
- between normal and mild atrophy of the thalamus
- moderate bilateral caudate atrophy
- basal forebrain remains normal, with no signs of tissue loss
- the pallidum shows no structural abnormalities indicative of atrophy
- between mild and moderate atrophy of the accumbens
- no signs of atrophy detected in the ventral dc
- between moderate and severe bilateral amygdala atrophy
- between normal and mild atrophy of the putamen
- mild bilateral hippocampus atrophy | PNFA |
NIFD_1_S_0225_MR_T1_mprage_S3_DIS3D_br_raw_20150518171530094_8_S260311_I493283 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the temporal lobe shows no structural abnormalities indicative of atrophy
- between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: middle frontal gyrus (between mild and moderate), sup. frontal gyrus (between normal and mild) and anterior orbital gyrus (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precuneus (between normal and mild) and supramarginal gyrus (between normal and mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between normal and mild) and middle cingulate gyrus (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (between normal and mild) and inf. occipital gyrus (mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal operculum (between normal and mild)
For the subcortical structures:
- basal forebrain appears structurally intact with no atrophic changes
- moderate bilateral putamen atrophy
- between mild and moderate bilateral pallidum atrophy
- thalamus maintains its normal morphology without atrophic features
- no signs of atrophy detected in the hippocampus
- between moderate and severe bilateral caudate atrophy
- the amygdala shows no structural abnormalities indicative of atrophy
- between mild and moderate bilateral accumbens atrophy
- ventral dc presents with a healthy appearance, free from atrophy
For the ventricles:
- between moderate and severe enlargement of the external csf
- 3rd ventricle maintains its normal volume without signs of enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected
- no pathological changes consistent with enlargement noted in the lateral ventricle
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected | PNFA |
ADNI_094_S_4282_MR_Accelerated_SAG_IR-SPGR__br_raw_20111020161253161_131_S125978_I261849 | On a T1-weighted brain MRI we observed:
For the ventricles:
- between mild and moderate bilateral inf. lateral ventricle enlargement
- external csf is free from enlargement or excessive growth
- between mild and moderate bilateral lateral ventricle enlargement
- 4th ventricle is free from enlargement or excessive growth
- no abnormal enlargement observed in the 3rd ventricle
For the cerebral cortex:
- limbic cortex maintains its normal morphology without atrophic features
- parietal lobe presents with a healthy appearance, free from atrophy
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: temporal pole (between normal and mild)
- no pathological changes consistent with atrophy detected in the insular cortex
- frontal lobe appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the occipital lobe
For the subcortical structures:
- between normal and mild atrophy of the caudate
- between mild and moderate bilateral ventral dc atrophy
- no degenerative or atrophic changes noted in the hippocampus
- mild atrophy of the amygdala
- between normal and mild right atrophy of the basal forebrain
- no pathological changes consistent with atrophy detected in the accumbens
- no signs of atrophy detected in the putamen
- between normal and mild bilateral pallidum atrophy
- thalamus remains normal, with no signs of tissue loss | AD |
NIFD_1_S_0145_MR_T1_mprage_S7_DIS3D_br_raw_20170817100405763_97_S597290_I890597 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (between moderate and severe), posterior insula (mild), frontal operculum (mild) and parietal operculum (between normal and mild)
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), sup. temporal gyrus (mild), temporal pole (between normal and mild), inf. temporal gyrus (between normal and mild) and middle temporal gyrus (between normal and mild)
- the occipital lobe shows no structural abnormalities indicative of atrophy
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate), anterior cingulate gyrus (between mild and moderate) and middle cingulate gyrus (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (moderate), medial frontal cortex (moderate), anterior orbital gyrus (between mild and moderate), lateral orbital gyrus (mild), posterior orbital gyrus (between moderate and severe) and sup. frontal gyrus medial segment (mild)
- parietal lobe maintains its normal morphology without atrophic features
For the subcortical structures:
- severe bilateral caudate atrophy
- no pathological changes consistent with atrophy detected in the basal forebrain
- severe bilateral amygdala atrophy
- mild bilateral thalamus atrophy
- mild bilateral pallidum atrophy
- no observable atrophic alterations in the ventral dc
- severe bilateral putamen atrophy
- severe bilateral accumbens atrophy
- severe bilateral hippocampus atrophy
For the ventricles:
- no signs of enlargement detected in the 4th ventricle
- no observable enlargement or abnormal growth in the external csf
- severe bilateral inf. lateral ventricle enlargement
- severe enlargement of the 3rd ventricle
- between moderate and severe bilateral lateral ventricle enlargement | BV |
ADNI_011_S_4949_MR_MPRAGE_br_raw_20120920143443577_47_S168024_I335369 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- pallidum maintains its normal morphology without atrophic features
- caudate maintains its normal morphology without atrophic features
- accumbens maintains its normal morphology without atrophic features
- basal forebrain presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the putamen
- between normal and mild atrophy of the hippocampus
- thalamus remains normal, with no signs of tissue loss
- between mild and moderate atrophy of the amygdala
- no observable atrophic alterations in the ventral dc
For the ventricles:
- no enlargement observed in the lateral ventricle
- 4th ventricle appears structurally intact, with no evidence of enlargement
- mild enlargement of the external csf
- no signs of enlargement detected in the inf. lateral ventricle
- no enlargement observed in the 3rd ventricle
For the cerebral cortex:
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: middle cingulate gyrus (between normal and mild)
- moderate atrophy of the temporal lobe, with focal volume loss observed in the following subregions: fusiform gyrus (severe), planum polare (mild), inf. temporal gyrus (moderate) and temporal pole (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. frontal gyrus (between normal and mild) and supplementary motor cortex (between normal and mild)
- insular cortex maintains its normal morphology without atrophic features
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in supramarginal gyrus (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between mild and moderate) | AD |
ADNI_023_S_5120_MR_MPRAGE_br_raw_20130515153204411_124_S189444_I372408 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no pathological changes consistent with enlargement noted in the 4th ventricle
- no enlargement observed in the external csf
- no observable enlargement or abnormal growth in the 3rd ventricle
- no signs of enlargement detected in the lateral ventricle
- no signs of enlargement detected in the inf. lateral ventricle
For the cerebral cortex:
- no evidence of atrophy or degeneration in the limbic cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus (between normal and mild), subcallosal area (mild) and supplementary motor cortex (mild)
- parietal lobe presents with a healthy appearance, free from atrophy
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in fusiform gyrus (mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior insula (mild)
For the subcortical structures:
- putamen appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the amygdala
- no signs of atrophy detected in the pallidum
- no observable atrophic alterations in the thalamus
- between normal and mild atrophy of the basal forebrain
- no signs of atrophy detected in the caudate
- accumbens appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the ventral dc
- hippocampus maintains its normal morphology without atrophic features | AD |
NIFD_1_S_0340_MR_T1_mprage_S3_DIS3D_br_raw_20170629005656608_54_S577855_I867606 | On a T1-weighted brain MRI we observed:
For the ventricles:
- between normal and mild enlargement of the lateral ventricle
- between normal and mild enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement
- no observable enlargement or abnormal growth in the 4th ventricle
- severe enlargement of the external csf
For the subcortical structures:
- basal forebrain appears structurally intact with no atrophic changes
- severe bilateral amygdala atrophy
- no evidence of atrophy or degeneration in the ventral dc
- moderate bilateral caudate atrophy
- mild bilateral putamen atrophy
- no evidence of atrophy or degeneration in the thalamus
- severe bilateral accumbens atrophy
- between normal and mild right atrophy of the pallidum
- between normal and mild atrophy of the hippocampus
For the cerebral cortex:
- occipital lobe appears structurally intact with no atrophic changes
- mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: planum polare (mild) and middle temporal gyrus (between moderate and severe)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe) and middle cingulate gyrus (between mild and moderate)
- between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (between moderate and severe)
- parietal lobe presents with a healthy appearance, free from atrophy
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), orbital inf. frontal gyrus (between mild and moderate), triangular inf. frontal gyrus (moderate), medial frontal cortex (between mild and moderate), middle frontal gyrus (between moderate and severe), lateral orbital gyrus (severe), medial orbital gyrus (severe), posterior orbital gyrus (between moderate and severe), sup. frontal gyrus (moderate) and sup. frontal gyrus medial segment (moderate) | BV |
NIFD_1_S_0198_MR_T1_mprage_S3_DIS3D_br_raw_20170817142403876_143_S598433_I892098 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no pathological changes consistent with enlargement noted in the external csf
- no signs of enlargement detected in the 4th ventricle
- mild enlargement of the 3rd ventricle
- between normal and mild left enlargement of the lateral ventricle
- inf. lateral ventricle maintains its normal volume without signs of enlargement
For the cerebral cortex:
- temporal lobe appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the parietal lobe
- no observable atrophic alterations in the frontal lobe
- no evidence of atrophy or degeneration in the limbic cortex
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. occipital gyrus (mild)
- no pathological changes consistent with atrophy detected in the insular cortex
For the subcortical structures:
- basal forebrain presents with a healthy appearance, free from atrophy
- between normal and mild bilateral hippocampus atrophy
- accumbens remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the caudate
- no degenerative or atrophic changes noted in the pallidum
- no signs of atrophy detected in the amygdala
- no signs of atrophy detected in the ventral dc
- thalamus appears structurally intact with no atrophic changes
- putamen appears structurally intact with no atrophic changes | CN |
NIFD_1_S_0206_MR_T1_mprage_S3_DIS3D_br_raw_20140901110000256_159_S229563_I441946 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
- severe enlargement of the inf. lateral ventricle
- between normal and mild enlargement of the 3rd ventricle
- between normal and mild enlargement of the external csf
For the subcortical structures:
- pallidum maintains its normal morphology without atrophic features
- ventral dc remains normal, with no signs of tissue loss
- mild left atrophy of the accumbens
- severe bilateral amygdala atrophy
- between normal and mild left atrophy of the thalamus
- mild atrophy of the putamen
- no evidence of atrophy or degeneration in the caudate
- basal forebrain remains normal, with no signs of tissue loss
- moderate left atrophy of the hippocampus
For the cerebral cortex:
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (moderate), central operculum (between normal and mild) and frontal operculum (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (between normal and mild) and postcentral gyrus medial segment (mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate) and parahippocampal gyrus (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle occipital gyrus (mild)
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: planum polare (between mild and moderate) and temporal pole (mild)
- between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: orbital inf. frontal gyrus (between normal and mild), triangular inf. frontal gyrus (between normal and mild), lateral orbital gyrus (moderate) and posterior orbital gyrus (mild) | PNFA |
ADNI_037_S_4410_MR_MPRAGE_br_raw_20111221112623954_118_S134218_I273584 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no evidence of atrophy or degeneration in the parietal lobe
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (between normal and mild) and lateral orbital gyrus (between mild and moderate)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (between normal and mild) and frontal operculum (between normal and mild)
- between normal and mild atrophy of the occipital lobe, with focal volume loss observed in the following subregions: inf. occipital gyrus (mild) and sup. occipital gyrus (mild)
- temporal lobe maintains its normal morphology without atrophic features
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (between normal and mild) and middle cingulate gyrus (between normal and mild)
For the ventricles:
- 4th ventricle remains within normal size parameters, with no enlargement detected
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- inf. lateral ventricle is free from enlargement or excessive growth
- no pathological changes consistent with enlargement noted in the external csf
- no pathological changes consistent with enlargement noted in the lateral ventricle
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the thalamus
- hippocampus appears structurally intact with no atrophic changes
- no signs of atrophy detected in the pallidum
- mild bilateral putamen atrophy
- basal forebrain maintains its normal morphology without atrophic features
- accumbens maintains its normal morphology without atrophic features
- between normal and mild left atrophy of the amygdala
- no pathological changes consistent with atrophy detected in the ventral dc
- no degenerative or atrophic changes noted in the caudate | CN |
ADNI_136_S_4269_MR_MPRAGE_br_raw_20111101161917308_144_S127664_I264215 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no signs of atrophy detected in the ventral dc
- no evidence of atrophy or degeneration in the thalamus
- no pathological changes consistent with atrophy detected in the accumbens
- putamen remains normal, with no signs of tissue loss
- pallidum maintains its normal morphology without atrophic features
- no signs of atrophy detected in the amygdala
- no pathological changes consistent with atrophy detected in the hippocampus
- no observable atrophic alterations in the caudate
- no observable atrophic alterations in the basal forebrain
For the ventricles:
- lateral ventricle remains within normal size parameters, with no enlargement detected
- no abnormal enlargement observed in the 4th ventricle
- mild enlargement of the 3rd ventricle
- the external csf shows no structural abnormalities indicative of enlargement
- no signs of enlargement detected in the inf. lateral ventricle
For the cerebral cortex:
- insular cortex remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the limbic cortex
- no observable atrophic alterations in the occipital lobe
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (moderate) and anterior orbital gyrus (mild)
- temporal lobe appears structurally intact with no atrophic changes
- between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild) | CN |
ADNI_041_S_4041_MR_MPRAGE_br_raw_20110525102129170_176_S109867_I237210 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- thalamus maintains its normal morphology without atrophic features
- the ventral dc shows no structural abnormalities indicative of atrophy
- putamen remains normal, with no signs of tissue loss
- pallidum maintains its normal morphology without atrophic features
- the amygdala shows no structural abnormalities indicative of atrophy
- mild bilateral accumbens atrophy
- no evidence of atrophy or degeneration in the basal forebrain
- caudate appears structurally intact with no atrophic changes
- between normal and mild atrophy of the hippocampus
For the ventricles:
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- no observable enlargement or abnormal growth in the lateral ventricle
- no abnormal enlargement observed in the inf. lateral ventricle
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- between mild and moderate enlargement of the external csf
For the cerebral cortex:
- no observable atrophic alterations in the parietal lobe
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal pole (mild) and posterior orbital gyrus (between normal and mild)
- no degenerative or atrophic changes noted in the insular cortex
- no pathological changes consistent with atrophy detected in the occipital lobe
- no signs of atrophy detected in the limbic cortex
- no observable atrophic alterations in the temporal lobe | CN |
ADNI_082_S_5184_MR_MPRAGE_br_raw_20130523103301800_81_S190368_I373616 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no signs of enlargement detected in the 3rd ventricle
- mild enlargement of the external csf
- no pathological changes consistent with enlargement noted in the lateral ventricle
- 4th ventricle remains within normal size parameters, with no enlargement detected
- between normal and mild enlargement of the inf. lateral ventricle
For the cerebral cortex:
- between mild and moderate atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (between normal and mild), middle temporal gyrus (between normal and mild) and sup. temporal gyrus (mild)
- insular cortex appears structurally intact with no atrophic changes
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between normal and mild) and middle cingulate gyrus (between normal and mild)
- mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: angular gyrus (mild), postcentral gyrus medial segment (between normal and mild), precuneus (between normal and mild) and supramarginal gyrus (between normal and mild)
- between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: medial frontal cortex (between normal and mild), sup. frontal gyrus (mild) and opercular inf. frontal gyrus (between normal and mild)
- occipital lobe appears structurally intact with no atrophic changes
For the subcortical structures:
- no evidence of atrophy or degeneration in the caudate
- between mild and moderate bilateral hippocampus atrophy
- between mild and moderate bilateral amygdala atrophy
- putamen remains normal, with no signs of tissue loss
- thalamus presents with a healthy appearance, free from atrophy
- no degenerative or atrophic changes noted in the pallidum
- ventral dc remains normal, with no signs of tissue loss
- basal forebrain presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the accumbens | AD |
NIFD_2_S_0022_MR_MT1__GradWarp__N3m_Br_20120907160236984_S164311_I332340 | On a T1-weighted brain MRI we observed:
For the ventricles:
- moderate enlargement of the lateral ventricle
- no signs of enlargement detected in the 3rd ventricle
- no observable enlargement or abnormal growth in the 4th ventricle
- between moderate and severe enlargement of the external csf
- mild enlargement of the inf. lateral ventricle
For the cerebral cortex:
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (between normal and mild)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (between normal and mild), gyrus rectus (between mild and moderate), opercular inf. frontal gyrus (between normal and mild), medial frontal cortex (between moderate and severe), middle frontal gyrus (severe), lateral orbital gyrus (mild), medial orbital gyrus (moderate), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus (between mild and moderate) and sup. frontal gyrus medial segment (moderate)
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (moderate), central operculum (mild) and frontal operculum (between mild and moderate)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle temporal gyrus (mild) and temporal pole (mild)
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe), middle cingulate gyrus (between normal and mild) and parahippocampal gyrus (between normal and mild)
- occipital lobe presents with a healthy appearance, free from atrophy
For the subcortical structures:
- between normal and mild atrophy of the ventral dc
- between normal and mild atrophy of the pallidum
- hippocampus appears structurally intact with no atrophic changes
- between mild and moderate bilateral amygdala atrophy
- moderate bilateral thalamus atrophy
- moderate bilateral putamen atrophy
- severe bilateral caudate atrophy
- no degenerative or atrophic changes noted in the basal forebrain
- severe bilateral accumbens atrophy | BV |
ADNI_014_S_4401_MR_MPRAGE_br_raw_20111202113251695_83_S131598_I269615 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no signs of atrophy detected in the accumbens
- amygdala presents with a healthy appearance, free from atrophy
- moderate bilateral basal forebrain atrophy
- no observable atrophic alterations in the caudate
- no pathological changes consistent with atrophy detected in the ventral dc
- thalamus appears structurally intact with no atrophic changes
- between normal and mild atrophy of the putamen
- no evidence of atrophy or degeneration in the pallidum
- hippocampus maintains its normal morphology without atrophic features
For the ventricles:
- external csf maintains its normal volume without signs of enlargement
- no abnormal enlargement observed in the 3rd ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
- no abnormal enlargement observed in the lateral ventricle
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
For the cerebral cortex:
- between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: postcentral gyrus (between normal and mild), supramarginal gyrus (between normal and mild) and sup. parietal lobule (between normal and mild)
- the insular cortex shows no structural abnormalities indicative of atrophy
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between normal and mild)
- limbic cortex maintains its normal morphology without atrophic features
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in transverse temporal gyrus (mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lateral orbital gyrus (between normal and mild) and sup. frontal gyrus (between normal and mild) | CN |
NIFD_1_S_0334_MR_T1_mprage_S3_DIS3D_br_raw_20170628221716446_133_S577518_I867161 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- putamen maintains its normal morphology without atrophic features
- between normal and mild atrophy of the hippocampus
- no observable atrophic alterations in the thalamus
- no degenerative or atrophic changes noted in the basal forebrain
- no pathological changes consistent with atrophy detected in the pallidum
- ventral dc maintains its normal morphology without atrophic features
- accumbens remains normal, with no signs of tissue loss
- caudate appears structurally intact with no atrophic changes
- severe bilateral amygdala atrophy
For the ventricles:
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- no signs of enlargement detected in the 4th ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
- between mild and moderate bilateral inf. lateral ventricle enlargement
- no signs of enlargement detected in the external csf
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (between normal and mild) and medial orbital gyrus (between normal and mild)
- mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (moderate)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus medial segment (between normal and mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (mild) and posterior insula (mild)
- occipital lobe maintains its normal morphology without atrophic features
- between moderate and severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (mild), planum temporale (between normal and mild), inf. temporal gyrus (mild) and temporal pole (between moderate and severe) | SV |
NIFD_1_S_0206_MR_T1_mprage_S3_DIS3D_br_raw_20140901110000256_159_S229563_I441946 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild left atrophy of the accumbens
- ventral dc remains normal, with no signs of tissue loss
- moderate left atrophy of the hippocampus
- mild atrophy of the putamen
- severe bilateral amygdala atrophy
- between normal and mild left atrophy of the thalamus
- no degenerative or atrophic changes noted in the pallidum
- no signs of atrophy detected in the basal forebrain
- no signs of atrophy detected in the caudate
For the cerebral cortex:
- between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: orbital inf. frontal gyrus (between normal and mild), triangular inf. frontal gyrus (between normal and mild), lateral orbital gyrus (moderate) and posterior orbital gyrus (mild)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (moderate), central operculum (between normal and mild) and frontal operculum (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (between normal and mild) and postcentral gyrus medial segment (mild)
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: planum polare (between mild and moderate) and temporal pole (mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate) and parahippocampal gyrus (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle occipital gyrus (mild)
For the ventricles:
- between normal and mild enlargement of the 3rd ventricle
- lateral ventricle remains within normal size parameters, with no enlargement detected
- 4th ventricle maintains its normal volume without signs of enlargement
- between normal and mild enlargement of the external csf
- severe enlargement of the inf. lateral ventricle | PNFA |
NIFD_1_S_0272_MR_t1_mprage__br_raw_20160903181430474_61_S496552_I772835 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- temporal lobe appears structurally intact with no atrophic changes
- limbic cortex maintains its normal morphology without atrophic features
- between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: precuneus (between normal and mild) and sup. parietal lobule (between normal and mild)
- insular cortex remains normal, with no signs of tissue loss
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (between normal and mild)
- occipital lobe appears structurally intact with no atrophic changes
For the ventricles:
- external csf appears structurally intact, with no evidence of enlargement
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- lateral ventricle maintains its normal volume without signs of enlargement
- no signs of enlargement detected in the 4th ventricle
- no observable enlargement or abnormal growth in the inf. lateral ventricle
For the subcortical structures:
- ventral dc presents with a healthy appearance, free from atrophy
- between normal and mild left atrophy of the basal forebrain
- between normal and mild atrophy of the thalamus
- accumbens appears structurally intact with no atrophic changes
- amygdala presents with a healthy appearance, free from atrophy
- no degenerative or atrophic changes noted in the caudate
- pallidum appears structurally intact with no atrophic changes
- between mild and moderate right atrophy of the hippocampus
- the putamen shows no structural abnormalities indicative of atrophy | CN |
NIFD_3_S_0004_MR_t1_mprage__br_raw_20160519002356300_116_S443026_I710048 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no degenerative or atrophic changes noted in the thalamus
- between moderate and severe bilateral caudate atrophy
- between mild and moderate atrophy of the putamen
- severe bilateral accumbens atrophy
- severe bilateral amygdala atrophy
- no observable atrophic alterations in the basal forebrain
- severe bilateral hippocampus atrophy
- mild bilateral ventral dc atrophy
- between mild and moderate bilateral pallidum atrophy
For the ventricles:
- between moderate and severe enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement
- 4th ventricle is free from enlargement or excessive growth
- between mild and moderate enlargement of the 3rd ventricle
- mild enlargement of the lateral ventricle
For the cerebral cortex:
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (severe), planum polare (between normal and mild), planum temporale (between normal and mild), inf. temporal gyrus (moderate), temporal pole (severe), middle temporal gyrus (moderate) and sup. temporal gyrus (mild)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (moderate), anterior cingulate gyrus (moderate) and parahippocampal gyrus (moderate)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (between mild and moderate), inf. occipital gyrus (between normal and mild) and sup. occipital gyrus (mild)
- no signs of atrophy detected in the parietal lobe
- between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (mild) and frontal operculum (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (mild) and medial frontal cortex (mild) | SV |
ADNI_018_S_4400_MR_MPRAGE_br_raw_20111220163832276_157_S134160_I273504 | On a T1-weighted brain MRI we observed:
For the ventricles:
- lateral ventricle remains within normal size parameters, with no enlargement detected
- 4th ventricle maintains its normal volume without signs of enlargement
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- no abnormal enlargement observed in the external csf
- no observable enlargement or abnormal growth in the 3rd ventricle
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (between normal and mild) and triangular inf. frontal gyrus (between normal and mild)
- no evidence of atrophy or degeneration in the insular cortex
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. occipital gyrus (between normal and mild)
- limbic cortex presents with a healthy appearance, free from atrophy
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus (between normal and mild)
- no evidence of atrophy or degeneration in the temporal lobe
For the subcortical structures:
- the putamen shows no structural abnormalities indicative of atrophy
- caudate appears structurally intact with no atrophic changes
- no signs of atrophy detected in the hippocampus
- no evidence of atrophy or degeneration in the thalamus
- no evidence of atrophy or degeneration in the amygdala
- pallidum remains normal, with no signs of tissue loss
- basal forebrain presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the ventral dc
- accumbens presents with a healthy appearance, free from atrophy | CN |
ADNI_100_S_5106_MR_MPRAGE_br_raw_20130423145847925_10_S187718_I368412 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- severe bilateral putamen atrophy
- moderate bilateral hippocampus atrophy
- between mild and moderate left atrophy of the basal forebrain
- between mild and moderate bilateral pallidum atrophy
- between normal and mild atrophy of the accumbens
- mild bilateral caudate atrophy
- mild bilateral thalamus atrophy
- between mild and moderate bilateral amygdala atrophy
- ventral dc appears structurally intact with no atrophic changes
For the ventricles:
- no enlargement observed in the 3rd ventricle
- mild bilateral lateral ventricle enlargement
- between normal and mild enlargement of the external csf
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- severe bilateral inf. lateral ventricle enlargement
For the cerebral cortex:
- no degenerative or atrophic changes noted in the occipital lobe
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus medial segment (between normal and mild)
- between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate) and posterior insula (mild)
- no evidence of atrophy or degeneration in the parietal lobe
- moderate bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (mild), middle temporal gyrus (between normal and mild) and sup. temporal gyrus (mild) | AD |
ADNI_137_S_4466_MR_MPRAGE_br_raw_20120130113126300_18_S138527_I280773 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no abnormal enlargement observed in the external csf
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- 4th ventricle appears structurally intact, with no evidence of enlargement
- between normal and mild enlargement of the 3rd ventricle
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
For the subcortical structures:
- no evidence of atrophy or degeneration in the hippocampus
- putamen presents with a healthy appearance, free from atrophy
- ventral dc appears structurally intact with no atrophic changes
- caudate maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the thalamus
- no evidence of atrophy or degeneration in the accumbens
- amygdala presents with a healthy appearance, free from atrophy
- basal forebrain appears structurally intact with no atrophic changes
- no signs of atrophy detected in the pallidum
For the cerebral cortex:
- no evidence of atrophy or degeneration in the parietal lobe
- limbic cortex maintains its normal morphology without atrophic features
- no signs of atrophy detected in the temporal lobe
- no degenerative or atrophic changes noted in the frontal lobe
- no pathological changes consistent with atrophy detected in the occipital lobe
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal operculum (between normal and mild) | CN |
ADNI_006_S_4150_MR_MPRAGE_br_raw_20110809103032948_1_S117925_I249403 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no observable enlargement or abnormal growth in the lateral ventricle
- no observable enlargement or abnormal growth in the 4th ventricle
- between normal and mild enlargement of the external csf
- no abnormal enlargement observed in the 3rd ventricle
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the ventral dc
- basal forebrain remains normal, with no signs of tissue loss
- accumbens maintains its normal morphology without atrophic features
- no observable atrophic alterations in the amygdala
- no observable atrophic alterations in the caudate
- pallidum remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the hippocampus
- no signs of atrophy detected in the putamen
- no evidence of atrophy or degeneration in the thalamus
For the cerebral cortex:
- parietal lobe remains normal, with no signs of tissue loss
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in triangular inf. frontal gyrus (between normal and mild)
- the insular cortex shows no structural abnormalities indicative of atrophy
- limbic cortex remains normal, with no signs of tissue loss
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (mild) and occipital fusiform gyrus (moderate)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (between mild and moderate) | CN |
NIFD_1_S_0034_MR_t1_mprage_S3_DIS3D_br_raw_20110428012718005_13_S105419_I229382 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in temporal pole (between mild and moderate)
- between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: central operculum (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (between normal and mild) and sup. occipital gyrus (between normal and mild)
- parietal lobe remains normal, with no signs of tissue loss
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior orbital gyrus (between mild and moderate)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (between normal and mild)
For the subcortical structures:
- hippocampus presents with a healthy appearance, free from atrophy
- pallidum remains normal, with no signs of tissue loss
- between normal and mild atrophy of the accumbens
- no evidence of atrophy or degeneration in the basal forebrain
- no evidence of atrophy or degeneration in the putamen
- no pathological changes consistent with atrophy detected in the amygdala
- no pathological changes consistent with atrophy detected in the caudate
- thalamus remains normal, with no signs of tissue loss
- no signs of atrophy detected in the ventral dc
For the ventricles:
- between normal and mild right enlargement of the inf. lateral ventricle
- mild bilateral lateral ventricle enlargement
- moderate enlargement of the 3rd ventricle
- no enlargement observed in the external csf
- 4th ventricle appears structurally intact, with no evidence of enlargement | CN |
ADNI_003_S_4373_MR_Accelerated_SAG_IR-SPGR__br_raw_20111227095734176_117_S134978_I274607 | On a T1-weighted brain MRI we observed:
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- no observable enlargement or abnormal growth in the 3rd ventricle
- severe enlargement of the external csf
- no abnormal enlargement observed in the 4th ventricle
- between normal and mild enlargement of the lateral ventricle
For the subcortical structures:
- between normal and mild left atrophy of the pallidum
- severe bilateral amygdala atrophy
- hippocampus maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the basal forebrain
- no degenerative or atrophic changes noted in the thalamus
- moderate bilateral caudate atrophy
- no signs of atrophy detected in the ventral dc
- severe bilateral accumbens atrophy
- moderate bilateral putamen atrophy
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (mild) and middle occipital gyrus (between normal and mild)
- moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (between normal and mild), medial frontal cortex (mild), middle frontal gyrus (between mild and moderate), medial orbital gyrus (between normal and mild), sup. frontal gyrus (between normal and mild), sup. frontal gyrus medial segment (between normal and mild), supplementary motor cortex (mild), gyrus rectus (between normal and mild) and precentral gyrus medial segment (between normal and mild)
- between moderate and severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild), inf. temporal gyrus (between mild and moderate), middle temporal gyrus (moderate) and temporal pole (between normal and mild)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe), middle cingulate gyrus (mild) and posterior cingulate gyrus (between mild and moderate)
- severe bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between mild and moderate), precuneus (severe), sup. parietal lobule (between normal and mild) and supramarginal gyrus (between normal and mild)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (moderate), posterior insula (moderate), central operculum (moderate) and parietal operculum (between normal and mild) | AD |
NIFD_1_S_0013_MR_T1_MPRAGE_long_S4_DIS3D__br_raw_20110204153537827_10_S99076_I216017 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- accumbens remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the putamen
- severe atrophy of the amygdala
- basal forebrain appears structurally intact with no atrophic changes
- the caudate shows no structural abnormalities indicative of atrophy
- pallidum presents with a healthy appearance, free from atrophy
- between mild and moderate atrophy of the hippocampus
- no evidence of atrophy or degeneration in the ventral dc
- thalamus appears structurally intact with no atrophic changes
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (between normal and mild) and cuneus (between normal and mild)
- between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: central operculum (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precuneus (between moderate and severe)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in triangular inf. frontal gyrus (mild) and subcallosal area (between normal and mild)
- moderate atrophy of the temporal lobe, with focal volume loss observed in the following subregions: planum polare (mild), inf. temporal gyrus (between mild and moderate) and temporal pole (moderate)
- between mild and moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (mild), anterior cingulate gyrus (between normal and mild) and posterior cingulate gyrus (between normal and mild)
For the ventricles:
- no observable enlargement or abnormal growth in the lateral ventricle
- no observable enlargement or abnormal growth in the 3rd ventricle
- 4th ventricle appears structurally intact, with no evidence of enlargement
- external csf appears structurally intact, with no evidence of enlargement
- severe enlargement of the inf. lateral ventricle | SV |
ADNI_128_S_4599_MR_MPRAGE_br_raw_20120319091450950_142_S144117_I290869 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no degenerative or atrophic changes noted in the pallidum
- between normal and mild left atrophy of the basal forebrain
- between normal and mild bilateral thalamus atrophy
- no observable atrophic alterations in the accumbens
- the caudate shows no structural abnormalities indicative of atrophy
- between normal and mild atrophy of the amygdala
- mild bilateral ventral dc atrophy
- between mild and moderate bilateral hippocampus atrophy
- putamen presents with a healthy appearance, free from atrophy
For the ventricles:
- no signs of enlargement detected in the lateral ventricle
- 4th ventricle remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the external csf
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- inf. lateral ventricle is free from enlargement or excessive growth
For the cerebral cortex:
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (between normal and mild)
- between mild and moderate bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (between moderate and severe) and temporal pole (between normal and mild)
- parietal lobe maintains its normal morphology without atrophic features
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (between normal and mild)
- no pathological changes consistent with atrophy detected in the frontal lobe
- no signs of atrophy detected in the insular cortex | CN |
ADNI_127_S_5058_MR_Accelerated_Sag_IR-FSPGR_br_raw_20130110155435101_67_S179905_I354645 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- basal forebrain appears structurally intact with no atrophic changes
- between normal and mild atrophy of the caudate
- hippocampus remains normal, with no signs of tissue loss
- between normal and mild bilateral putamen atrophy
- no signs of atrophy detected in the thalamus
- pallidum maintains its normal morphology without atrophic features
- amygdala appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the ventral dc
- moderate bilateral accumbens atrophy
For the ventricles:
- no pathological changes consistent with enlargement noted in the lateral ventricle
- mild enlargement of the 3rd ventricle
- between normal and mild enlargement of the external csf
- no abnormal enlargement observed in the 4th ventricle
- moderate bilateral inf. lateral ventricle enlargement
For the cerebral cortex:
- mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: sup. parietal lobule (between normal and mild), supramarginal gyrus (between normal and mild), angular gyrus (mild) and precuneus (between normal and mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (between normal and mild)
- insular cortex appears structurally intact with no atrophic changes
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (mild), anterior orbital gyrus (between mild and moderate), lateral orbital gyrus (mild), supplementary motor cortex (between normal and mild) and triangular inf. frontal gyrus (between normal and mild)
- no evidence of atrophy or degeneration in the temporal lobe
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lingual gyrus (between normal and mild) and occipital fusiform gyrus (mild) | AD |
ADNI_072_S_4391_MR_MPRAGE_br_raw_20120110102851585_134_S135851_I276963 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precuneus (mild)
- frontal lobe maintains its normal morphology without atrophic features
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lingual gyrus (between mild and moderate)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parietal operculum (between normal and mild)
- no signs of atrophy detected in the temporal lobe
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: middle cingulate gyrus (between normal and mild), posterior cingulate gyrus (between normal and mild) and anterior cingulate gyrus (between normal and mild)
For the subcortical structures:
- no signs of atrophy detected in the hippocampus
- accumbens maintains its normal morphology without atrophic features
- pallidum appears structurally intact with no atrophic changes
- no signs of atrophy detected in the putamen
- no observable atrophic alterations in the ventral dc
- between normal and mild left atrophy of the basal forebrain
- no observable atrophic alterations in the thalamus
- caudate appears structurally intact with no atrophic changes
- between normal and mild right atrophy of the amygdala
For the ventricles:
- external csf remains within normal size parameters, with no enlargement detected
- inf. lateral ventricle is free from enlargement or excessive growth
- 4th ventricle appears structurally intact, with no evidence of enlargement
- no signs of enlargement detected in the 3rd ventricle
- lateral ventricle remains within normal size parameters, with no enlargement detected | CN |
NIFD_1_S_0233_MR_t1_mprage__br_raw_20160902124800286_27_S495603_I771741 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- no signs of enlargement detected in the 4th ventricle
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no enlargement observed in the external csf
- no abnormal enlargement observed in the lateral ventricle
For the subcortical structures:
- putamen presents with a healthy appearance, free from atrophy
- accumbens appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the amygdala
- the basal forebrain shows no structural abnormalities indicative of atrophy
- the hippocampus shows no structural abnormalities indicative of atrophy
- pallidum maintains its normal morphology without atrophic features
- thalamus maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the ventral dc
- caudate appears structurally intact with no atrophic changes
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (between normal and mild) and sup. occipital gyrus (between normal and mild)
- no degenerative or atrophic changes noted in the temporal lobe
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (between normal and mild)
- no pathological changes consistent with atrophy detected in the insular cortex
- limbic cortex appears structurally intact with no atrophic changes
- no observable atrophic alterations in the parietal lobe | CN |
ADNI_010_S_4345_MR_MPRAGE_br_raw_20120201140453298_1_S139219_I282005 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital pole (between normal and mild)
- mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (moderate), frontal operculum (between normal and mild) and parietal operculum (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. parietal lobule (between normal and mild) and supramarginal gyrus (mild)
- mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (between normal and mild), opercular inf. frontal gyrus (between normal and mild), triangular inf. frontal gyrus (between normal and mild) and subcallosal area (mild)
- no signs of atrophy detected in the temporal lobe
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (mild)
For the ventricles:
- no abnormal enlargement observed in the 4th ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
- no signs of enlargement detected in the 3rd ventricle
- inf. lateral ventricle is free from enlargement or excessive growth
- no observable enlargement or abnormal growth in the external csf
For the subcortical structures:
- no observable atrophic alterations in the basal forebrain
- caudate remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the hippocampus
- no evidence of atrophy or degeneration in the accumbens
- no pathological changes consistent with atrophy detected in the putamen
- thalamus maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the amygdala
- no degenerative or atrophic changes noted in the ventral dc
- no evidence of atrophy or degeneration in the pallidum | CN |
ADNI_073_S_5016_MR_MPRAGE_br_raw_20121025143537810_122_S172362_I342679 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no observable enlargement or abnormal growth in the lateral ventricle
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- no signs of enlargement detected in the external csf
- no pathological changes consistent with enlargement noted in the 4th ventricle
For the subcortical structures:
- no evidence of atrophy or degeneration in the ventral dc
- between normal and mild atrophy of the hippocampus
- pallidum maintains its normal morphology without atrophic features
- thalamus remains normal, with no signs of tissue loss
- caudate maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the accumbens
- basal forebrain appears structurally intact with no atrophic changes
- between normal and mild atrophy of the amygdala
- no evidence of atrophy or degeneration in the putamen
For the cerebral cortex:
- no signs of atrophy detected in the limbic cortex
- parietal lobe presents with a healthy appearance, free from atrophy
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus medial segment (mild) and sup. frontal gyrus medial segment (mild)
- mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: posterior insula (between normal and mild), parietal operculum (between normal and mild) and central operculum (between normal and mild)
- between normal and mild atrophy of the temporal lobe | AD |
NIFD_1_S_0070_MR_t1_mprage_S3_DIS3D_br_raw_20111209154511930_109_S132532_I271023 | On a T1-weighted brain MRI we observed:
For the ventricles:
- between moderate and severe bilateral lateral ventricle enlargement
- between mild and moderate enlargement of the 3rd ventricle
- 4th ventricle appears structurally intact, with no evidence of enlargement
- between moderate and severe enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement
For the subcortical structures:
- moderate bilateral pallidum atrophy
- severe bilateral amygdala atrophy
- between mild and moderate bilateral thalamus atrophy
- severe bilateral caudate atrophy
- between mild and moderate atrophy of the hippocampus
- between normal and mild bilateral ventral dc atrophy
- basal forebrain appears structurally intact with no atrophic changes
- severe bilateral accumbens atrophy
- severe bilateral putamen atrophy
For the cerebral cortex:
- occipital lobe appears structurally intact with no atrophic changes
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (between mild and moderate), gyrus rectus (severe), medial frontal cortex (severe), middle frontal gyrus (mild), anterior orbital gyrus (mild), lateral orbital gyrus (mild), medial orbital gyrus (severe), posterior orbital gyrus (severe), subcallosal area (between normal and mild), sup. frontal gyrus (severe), sup. frontal gyrus medial segment (severe), opercular inf. frontal gyrus (mild) and orbital inf. frontal gyrus (mild)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (mild), central operculum (between normal and mild) and frontal operculum (between normal and mild)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (moderate), anterior cingulate gyrus (severe) and parahippocampal gyrus (between normal and mild)
- no degenerative or atrophic changes noted in the parietal lobe
- between mild and moderate atrophy of the temporal lobe, with focal volume loss observed in the following subregions: middle temporal gyrus (moderate), transverse temporal gyrus (between normal and mild) and temporal pole (between mild and moderate) | BV |
ADNI_018_S_5074_MR_MPRAGE_br_raw_20130215105938763_57_S182436_I360314 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no observable atrophic alterations in the insular cortex
- limbic cortex presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the frontal lobe
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precuneus (between normal and mild) and sup. parietal lobule (between normal and mild)
- no signs of atrophy detected in the occipital lobe
For the subcortical structures:
- accumbens presents with a healthy appearance, free from atrophy
- moderate bilateral hippocampus atrophy
- thalamus presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the ventral dc
- no observable atrophic alterations in the basal forebrain
- pallidum appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the amygdala
- putamen maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the caudate
For the ventricles:
- no abnormal enlargement observed in the external csf
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- lateral ventricle maintains its normal volume without signs of enlargement
- mild right enlargement of the inf. lateral ventricle
- no signs of enlargement detected in the 4th ventricle | AD |
ADNI_130_S_4984_MR_MPRAGE_br_raw_20121025102139930_110_S172131_I342274 | On a T1-weighted brain MRI we observed:
For the ventricles:
- mild bilateral inf. lateral ventricle enlargement
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- mild enlargement of the external csf
- between normal and mild left enlargement of the lateral ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
For the subcortical structures:
- mild bilateral hippocampus atrophy
- pallidum maintains its normal morphology without atrophic features
- ventral dc maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the thalamus
- between normal and mild left atrophy of the caudate
- the basal forebrain shows no structural abnormalities indicative of atrophy
- between normal and mild atrophy of the accumbens
- severe bilateral amygdala atrophy
- no observable atrophic alterations in the putamen
For the cerebral cortex:
- severe bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between mild and moderate), postcentral gyrus (between normal and mild), precuneus (moderate), sup. parietal lobule (severe) and supramarginal gyrus (between mild and moderate)
- moderate atrophy of the temporal lobe, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild), inf. temporal gyrus (between moderate and severe) and middle temporal gyrus (mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (moderate)
- insular cortex presents with a healthy appearance, free from atrophy
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in triangular inf. frontal gyrus (between mild and moderate), middle frontal gyrus (between normal and mild) and precentral gyrus (between mild and moderate)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle occipital gyrus (between normal and mild) and occipital pole (moderate) | AD |
NIFD_2_S_0016_MR_MT1__GradWarp__N3m_Br_20130131161214414_S180124_I357405 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe) and entorhinal area (mild)
- moderate atrophy of the frontal lobe, with focal volume loss observed in the following subregions: gyrus rectus (severe), medial frontal cortex (between mild and moderate), anterior orbital gyrus (mild), lateral orbital gyrus (between mild and moderate), medial orbital gyrus (severe), posterior orbital gyrus (moderate), precentral gyrus medial segment (between normal and mild), sup. frontal gyrus medial segment (moderate), middle frontal gyrus (between normal and mild) and sup. frontal gyrus (between normal and mild)
- no pathological changes consistent with atrophy detected in the parietal lobe
- mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (between normal and mild) and transverse temporal gyrus (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (between normal and mild)
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (between normal and mild)
For the ventricles:
- mild bilateral lateral ventricle enlargement
- severe bilateral inf. lateral ventricle enlargement
- moderate enlargement of the external csf
- no enlargement observed in the 4th ventricle
- moderate enlargement of the 3rd ventricle
For the subcortical structures:
- no evidence of atrophy or degeneration in the basal forebrain
- severe bilateral putamen atrophy
- between normal and mild atrophy of the thalamus
- severe bilateral accumbens atrophy
- severe bilateral caudate atrophy
- between normal and mild left atrophy of the ventral dc
- between moderate and severe bilateral pallidum atrophy
- severe bilateral amygdala atrophy
- between mild and moderate atrophy of the hippocampus | BV |
NIFD_1_S_0233_MR_t1_mprage__br_raw_20160902124800286_27_S495603_I771741 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (between normal and mild) and sup. occipital gyrus (between normal and mild)
- no observable atrophic alterations in the limbic cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (between normal and mild)
- no evidence of atrophy or degeneration in the temporal lobe
- parietal lobe remains normal, with no signs of tissue loss
- no signs of atrophy detected in the insular cortex
For the ventricles:
- 4th ventricle is free from enlargement or excessive growth
- 3rd ventricle maintains its normal volume without signs of enlargement
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no signs of enlargement detected in the inf. lateral ventricle
- no signs of enlargement detected in the external csf
For the subcortical structures:
- no observable atrophic alterations in the pallidum
- no observable atrophic alterations in the basal forebrain
- the putamen shows no structural abnormalities indicative of atrophy
- hippocampus remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the amygdala
- caudate remains normal, with no signs of tissue loss
- no signs of atrophy detected in the thalamus
- accumbens remains normal, with no signs of tissue loss
- no observable atrophic alterations in the ventral dc | CN |
NIFD_1_S_0021_MR_t1_mprage_S3_DIS3D_br_raw_20110825152854512_133_S120382_I252863 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (between normal and mild) and middle occipital gyrus (between mild and moderate)
- insular cortex maintains its normal morphology without atrophic features
- parietal lobe presents with a healthy appearance, free from atrophy
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in temporal pole (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior orbital gyrus (mild) and supplementary motor cortex (between normal and mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (between normal and mild)
For the subcortical structures:
- between normal and mild bilateral caudate atrophy
- no evidence of atrophy or degeneration in the pallidum
- hippocampus maintains its normal morphology without atrophic features
- no signs of atrophy detected in the amygdala
- no pathological changes consistent with atrophy detected in the putamen
- no observable atrophic alterations in the ventral dc
- mild left atrophy of the basal forebrain
- the thalamus shows no structural abnormalities indicative of atrophy
- accumbens presents with a healthy appearance, free from atrophy
For the ventricles:
- no abnormal enlargement observed in the inf. lateral ventricle
- no abnormal enlargement observed in the external csf
- no enlargement observed in the 4th ventricle
- no signs of enlargement detected in the 3rd ventricle
- lateral ventricle remains within normal size parameters, with no enlargement detected | CN |
ADNI_023_S_5120_MR_MPRAGE_br_raw_20130515153204411_124_S189444_I372408 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior insula (mild)
- no pathological changes consistent with atrophy detected in the limbic cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus (between normal and mild), subcallosal area (mild) and supplementary motor cortex (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (between normal and mild)
- no evidence of atrophy or degeneration in the parietal lobe
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in fusiform gyrus (mild)
For the subcortical structures:
- no observable atrophic alterations in the accumbens
- no evidence of atrophy or degeneration in the amygdala
- no pathological changes consistent with atrophy detected in the putamen
- pallidum maintains its normal morphology without atrophic features
- caudate remains normal, with no signs of tissue loss
- no signs of atrophy detected in the hippocampus
- between normal and mild atrophy of the basal forebrain
- ventral dc remains normal, with no signs of tissue loss
- thalamus remains normal, with no signs of tissue loss
For the ventricles:
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- the external csf shows no structural abnormalities indicative of enlargement
- no abnormal enlargement observed in the 4th ventricle
- no enlargement observed in the 3rd ventricle
- lateral ventricle remains within normal size parameters, with no enlargement detected | AD |
ADNI_094_S_4089_MR_Accelerated_SAG_IR-SPGR__br_raw_20110630122131904_28_S113223_I242720 | On a T1-weighted brain MRI we observed:
For the ventricles:
- between normal and mild enlargement of the inf. lateral ventricle
- between mild and moderate enlargement of the external csf
- no enlargement observed in the lateral ventricle
- 4th ventricle appears structurally intact, with no evidence of enlargement
- 3rd ventricle remains within normal size parameters, with no enlargement detected
For the subcortical structures:
- no evidence of atrophy or degeneration in the thalamus
- the pallidum shows no structural abnormalities indicative of atrophy
- the ventral dc shows no structural abnormalities indicative of atrophy
- between normal and mild atrophy of the hippocampus
- no signs of atrophy detected in the caudate
- between normal and mild atrophy of the putamen
- severe bilateral amygdala atrophy
- basal forebrain maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the accumbens
For the cerebral cortex:
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior insula (between normal and mild)
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: planum polare (between normal and mild) and temporal pole (between mild and moderate)
- mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (mild) and parahippocampal gyrus (between mild and moderate)
- no degenerative or atrophic changes noted in the occipital lobe
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior orbital gyrus (mild) and medial frontal cortex (between normal and mild)
- mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: angular gyrus (mild) and precuneus (between normal and mild) | AD |
NIFD_1_S_0147_MR_T1_mprage_S3_DIS3D_br_raw_20140612224636364_53_S222067_I430635 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- the thalamus shows no structural abnormalities indicative of atrophy
- the hippocampus shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the amygdala
- no observable atrophic alterations in the ventral dc
- between normal and mild atrophy of the caudate
- between normal and mild atrophy of the pallidum
- putamen remains normal, with no signs of tissue loss
- between mild and moderate bilateral accumbens atrophy
- no pathological changes consistent with atrophy detected in the basal forebrain
For the ventricles:
- 4th ventricle maintains its normal volume without signs of enlargement
- no pathological changes consistent with enlargement noted in the external csf
- no abnormal enlargement observed in the 3rd ventricle
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- lateral ventricle remains within normal size parameters, with no enlargement detected
For the cerebral cortex:
- the insular cortex shows no structural abnormalities indicative of atrophy
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (between normal and mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (mild)
- occipital lobe remains normal, with no signs of tissue loss
- moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild), medial frontal cortex (mild), middle frontal gyrus (moderate), medial orbital gyrus (between normal and mild) and precentral gyrus (between normal and mild)
- parietal lobe maintains its normal morphology without atrophic features | PNFA |
NIFD_1_S_0154_MR_T1_mprage_S3_DIS3D_br_raw_20140612232751791_69_S222114_I430686 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no degenerative or atrophic changes noted in the putamen
- no evidence of atrophy or degeneration in the amygdala
- basal forebrain appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the accumbens
- no signs of atrophy detected in the hippocampus
- no observable atrophic alterations in the ventral dc
- caudate remains normal, with no signs of tissue loss
- thalamus remains normal, with no signs of tissue loss
- pallidum appears structurally intact with no atrophic changes
For the ventricles:
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- no abnormal enlargement observed in the 3rd ventricle
- external csf appears structurally intact, with no evidence of enlargement
- no signs of enlargement detected in the inf. lateral ventricle
- 4th ventricle remains within normal size parameters, with no enlargement detected
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the limbic cortex
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (between normal and mild) and sup. occipital gyrus (mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (between normal and mild), anterior orbital gyrus (between normal and mild), posterior orbital gyrus (between normal and mild), sup. frontal gyrus medial segment (between normal and mild) and supplementary motor cortex (between normal and mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in central operculum (between normal and mild)
- temporal lobe appears structurally intact with no atrophic changes
- mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: sup. parietal lobule (between normal and mild) and supramarginal gyrus (mild) | CN |
ADNI_018_S_4733_MR_MPRAGE_br_raw_20120523122532411_63_S151381_I306069 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no observable atrophic alterations in the putamen
- no signs of atrophy detected in the hippocampus
- basal forebrain appears structurally intact with no atrophic changes
- thalamus remains normal, with no signs of tissue loss
- ventral dc presents with a healthy appearance, free from atrophy
- between normal and mild left atrophy of the pallidum
- no pathological changes consistent with atrophy detected in the accumbens
- caudate remains normal, with no signs of tissue loss
- mild atrophy of the amygdala
For the ventricles:
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no signs of enlargement detected in the 4th ventricle
- the external csf shows no structural abnormalities indicative of enlargement
- no signs of enlargement detected in the 3rd ventricle
- lateral ventricle maintains its normal volume without signs of enlargement
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between mild and moderate)
- no evidence of atrophy or degeneration in the insular cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (between normal and mild)
- no degenerative or atrophic changes noted in the parietal lobe
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (mild), anterior cingulate gyrus (between mild and moderate), middle cingulate gyrus (mild) and parahippocampal gyrus (moderate)
- temporal lobe remains normal, with no signs of tissue loss | AD |
ADNI_094_S_4737_MR_Accelerated_SAG_IR-SPGR__br_raw_20120612083656502_30_S153539_I309933 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (between mild and moderate), sup. temporal gyrus (between normal and mild) and transverse temporal gyrus (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precuneus (mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between normal and mild) and posterior cingulate gyrus (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (mild) and opercular inf. frontal gyrus (between moderate and severe)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in central operculum (between normal and mild) and parietal operculum (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (mild)
For the ventricles:
- between normal and mild left enlargement of the lateral ventricle
- no signs of enlargement detected in the external csf
- between mild and moderate bilateral inf. lateral ventricle enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected
- no enlargement observed in the 3rd ventricle
For the subcortical structures:
- basal forebrain maintains its normal morphology without atrophic features
- hippocampus appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the pallidum
- accumbens remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the ventral dc
- mild bilateral caudate atrophy
- between normal and mild atrophy of the putamen
- no pathological changes consistent with atrophy detected in the thalamus
- between normal and mild bilateral amygdala atrophy | AD |
NIFD_1_S_0161_MR_T1_mprage_S3_DIS3D_br_raw_20140630121148243_153_S223484_I433506 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no signs of enlargement detected in the lateral ventricle
- no abnormal enlargement observed in the inf. lateral ventricle
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- external csf remains within normal size parameters, with no enlargement detected
- moderate enlargement of the 4th ventricle
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the thalamus
- caudate appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the pallidum
- no evidence of atrophy or degeneration in the amygdala
- between normal and mild atrophy of the accumbens
- no pathological changes consistent with atrophy detected in the hippocampus
- no evidence of atrophy or degeneration in the ventral dc
- basal forebrain presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the putamen
For the cerebral cortex:
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (between normal and mild) and middle temporal gyrus (between mild and moderate)
- mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), precuneus (between normal and mild), sup. parietal lobule (between normal and mild), supramarginal gyrus (mild) and postcentral gyrus medial segment (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (between normal and mild), subcallosal area (between normal and mild) and medial orbital gyrus (between normal and mild)
- between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (mild) and parietal operculum (between mild and moderate)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between normal and mild)
- occipital lobe appears structurally intact with no atrophic changes | CN |
NIFD_1_S_0070_MR_t1_mprage_S3_DIS3D_br_raw_20111209154511930_109_S132532_I271023 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- severe bilateral caudate atrophy
- moderate bilateral pallidum atrophy
- severe bilateral amygdala atrophy
- between mild and moderate bilateral thalamus atrophy
- between normal and mild bilateral ventral dc atrophy
- no observable atrophic alterations in the basal forebrain
- between mild and moderate atrophy of the hippocampus
- severe bilateral accumbens atrophy
- severe bilateral putamen atrophy
For the ventricles:
- 4th ventricle remains within normal size parameters, with no enlargement detected
- severe bilateral inf. lateral ventricle enlargement
- between moderate and severe bilateral lateral ventricle enlargement
- between mild and moderate enlargement of the 3rd ventricle
- between moderate and severe enlargement of the external csf
For the cerebral cortex:
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (mild), central operculum (between normal and mild) and frontal operculum (between normal and mild)
- between mild and moderate atrophy of the temporal lobe, with focal volume loss observed in the following subregions: middle temporal gyrus (moderate), transverse temporal gyrus (between normal and mild) and temporal pole (between mild and moderate)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (between mild and moderate), gyrus rectus (severe), medial frontal cortex (severe), middle frontal gyrus (mild), anterior orbital gyrus (mild), lateral orbital gyrus (mild), medial orbital gyrus (severe), posterior orbital gyrus (severe), subcallosal area (between normal and mild), sup. frontal gyrus (severe), sup. frontal gyrus medial segment (severe), opercular inf. frontal gyrus (mild) and orbital inf. frontal gyrus (mild)
- no evidence of atrophy or degeneration in the parietal lobe
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (moderate), anterior cingulate gyrus (severe) and parahippocampal gyrus (between normal and mild)
- occipital lobe presents with a healthy appearance, free from atrophy | BV |
NIFD_1_S_0094_MR_T1_mprage_S3_DIS3D_br_raw_20120819122501416_127_S161376_I324612 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no degenerative or atrophic changes noted in the hippocampus
- between normal and mild bilateral caudate atrophy
- ventral dc appears structurally intact with no atrophic changes
- between normal and mild atrophy of the accumbens
- no evidence of atrophy or degeneration in the pallidum
- between normal and mild left atrophy of the amygdala
- no evidence of atrophy or degeneration in the putamen
- between mild and moderate bilateral thalamus atrophy
- no signs of atrophy detected in the basal forebrain
For the ventricles:
- no signs of enlargement detected in the 3rd ventricle
- no enlargement observed in the 4th ventricle
- inf. lateral ventricle is free from enlargement or excessive growth
- between mild and moderate enlargement of the external csf
- no enlargement observed in the lateral ventricle
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (between mild and moderate)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (between normal and mild)
- mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum polare (mild), inf. temporal gyrus (between normal and mild) and middle temporal gyrus (between mild and moderate)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parahippocampal gyrus (mild) | BV |
NIFD_1_S_0086_MR_T1_mprage_S3_DIS3D_br_raw_20120819180116961_50_S161507_I324763 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild atrophy of the hippocampus
- between normal and mild atrophy of the putamen
- mild atrophy of the caudate
- severe bilateral amygdala atrophy
- no signs of atrophy detected in the ventral dc
- severe bilateral accumbens atrophy
- basal forebrain appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the thalamus
- mild atrophy of the pallidum
For the cerebral cortex:
- between moderate and severe atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (between moderate and severe), anterior cingulate gyrus (moderate) and parahippocampal gyrus (moderate)
- moderate atrophy of the insular cortex, with focal volume loss observed in the following subregions: posterior insula (between mild and moderate), central operculum (mild), parietal operculum (mild) and anterior insula (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (between normal and mild) and medial frontal cortex (between mild and moderate)
- occipital lobe maintains its normal morphology without atrophic features
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (between moderate and severe), planum polare (mild), inf. temporal gyrus (severe), middle temporal gyrus (severe), sup. temporal gyrus (between moderate and severe) and temporal pole (severe)
- between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: angular gyrus (mild) and precuneus (between normal and mild)
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- mild enlargement of the external csf
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- no signs of enlargement detected in the 4th ventricle
- between normal and mild left enlargement of the lateral ventricle | SV |
NIFD_1_S_0059_MR_t1_mprage_S3_DIS3D_br_raw_20111019183350018_67_S125844_I261661 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- basal forebrain remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the ventral dc
- between moderate and severe bilateral pallidum atrophy
- severe bilateral caudate atrophy
- no degenerative or atrophic changes noted in the thalamus
- severe bilateral putamen atrophy
- severe bilateral accumbens atrophy
- mild bilateral hippocampus atrophy
- severe bilateral amygdala atrophy
For the cerebral cortex:
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate), anterior cingulate gyrus (severe) and parahippocampal gyrus (between mild and moderate)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (between mild and moderate), gyrus rectus (severe), opercular inf. frontal gyrus (moderate), triangular inf. frontal gyrus (between mild and moderate), medial frontal cortex (between moderate and severe), middle frontal gyrus (moderate), anterior orbital gyrus (between moderate and severe), medial orbital gyrus (between mild and moderate), posterior orbital gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (between moderate and severe) and supplementary motor cortex (mild)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between mild and moderate) and frontal operculum (severe)
- no degenerative or atrophic changes noted in the parietal lobe
- occipital lobe maintains its normal morphology without atrophic features
- between normal and mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: temporal pole (severe)
For the ventricles:
- moderate bilateral lateral ventricle enlargement
- no abnormal enlargement observed in the 4th ventricle
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- severe enlargement of the external csf
- mild enlargement of the 3rd ventricle | BV |
ADNI_127_S_4992_MR_Accelerated_Sag_IR-SPGR__br_raw_20121025174442023_45_S172372_I342695 | On a T1-weighted brain MRI we observed:
For the ventricles:
- moderate enlargement of the 3rd ventricle
- no observable enlargement or abnormal growth in the 4th ventricle
- between mild and moderate enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement
- between moderate and severe bilateral lateral ventricle enlargement
For the subcortical structures:
- between mild and moderate bilateral hippocampus atrophy
- between mild and moderate bilateral putamen atrophy
- ventral dc maintains its normal morphology without atrophic features
- no signs of atrophy detected in the basal forebrain
- severe bilateral amygdala atrophy
- between mild and moderate bilateral accumbens atrophy
- between normal and mild right atrophy of the pallidum
- thalamus appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the caudate
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (mild)
- mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: middle temporal gyrus (between moderate and severe) and sup. temporal gyrus (mild)
- between moderate and severe bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (mild), precuneus (severe) and sup. parietal lobule (between normal and mild)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between normal and mild)
- between moderate and severe bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: cuneus (between normal and mild), lingual gyrus (mild), middle occipital gyrus (moderate), sup. occipital gyrus (between mild and moderate) and occipital pole (mild)
- between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: parietal operculum (between mild and moderate) | AD |
NIFD_1_S_0178_MR_T1_mprage_S3_DIS3D_br_raw_20140831173120988_76_S229016_I441330 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- caudate maintains its normal morphology without atrophic features
- accumbens remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the putamen
- hippocampus appears structurally intact with no atrophic changes
- thalamus maintains its normal morphology without atrophic features
- the basal forebrain shows no structural abnormalities indicative of atrophy
- pallidum appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the amygdala
- no pathological changes consistent with atrophy detected in the ventral dc
For the ventricles:
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- lateral ventricle remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- no abnormal enlargement observed in the external csf
- no signs of enlargement detected in the 4th ventricle
For the cerebral cortex:
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in central operculum (between normal and mild)
- no degenerative or atrophic changes noted in the parietal lobe
- no pathological changes consistent with atrophy detected in the limbic cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (between normal and mild), lateral orbital gyrus (mild) and subcallosal area (mild)
- occipital lobe maintains its normal morphology without atrophic features
- temporal lobe appears structurally intact with no atrophic changes | CN |
ADNI_073_S_4155_MR_MPRAGE_br_raw_20110728173009254_2_S116720_I247636 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (mild)
- between normal and mild atrophy of the parietal lobe
- no degenerative or atrophic changes noted in the insular cortex
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (between normal and mild), sup. frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (between normal and mild)
- no signs of atrophy detected in the temporal lobe
For the ventricles:
- no observable enlargement or abnormal growth in the 4th ventricle
- mild enlargement of the external csf
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- no enlargement observed in the lateral ventricle
For the subcortical structures:
- no evidence of atrophy or degeneration in the hippocampus
- the putamen shows no structural abnormalities indicative of atrophy
- accumbens appears structurally intact with no atrophic changes
- no signs of atrophy detected in the thalamus
- the basal forebrain shows no structural abnormalities indicative of atrophy
- pallidum maintains its normal morphology without atrophic features
- amygdala maintains its normal morphology without atrophic features
- no observable atrophic alterations in the caudate
- ventral dc appears structurally intact with no atrophic changes | CN |
ADNI_130_S_4971_MR_MPRAGE_br_raw_20121025110023272_8_S172180_I342338 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: middle frontal gyrus (between normal and mild), posterior orbital gyrus (mild), subcallosal area (mild), sup. frontal gyrus (mild) and orbital inf. frontal gyrus (between normal and mild)
- no evidence of atrophy or degeneration in the occipital lobe
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. temporal gyrus (between normal and mild)
- mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between mild and moderate), postcentral gyrus (mild) and supramarginal gyrus (between normal and mild)
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate), posterior insula (mild), central operculum (between normal and mild) and frontal operculum (between normal and mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (between normal and mild) and middle cingulate gyrus (between mild and moderate)
For the ventricles:
- moderate enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement
- between normal and mild left enlargement of the lateral ventricle
- no signs of enlargement detected in the 4th ventricle
- no observable enlargement or abnormal growth in the external csf
For the subcortical structures:
- no evidence of atrophy or degeneration in the ventral dc
- between mild and moderate bilateral putamen atrophy
- between normal and mild atrophy of the pallidum
- between normal and mild bilateral accumbens atrophy
- no evidence of atrophy or degeneration in the basal forebrain
- between normal and mild bilateral caudate atrophy
- moderate bilateral thalamus atrophy
- mild bilateral hippocampus atrophy
- moderate bilateral amygdala atrophy | AD |
NIFD_1_S_0026_MR_t1_mprage_S3_DIS3D_br_raw_20110412101938141_66_S103861_I227149 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- between normal and mild atrophy of the thalamus
- severe bilateral hippocampus atrophy
- severe bilateral putamen atrophy
- ventral dc appears structurally intact with no atrophic changes
- severe bilateral caudate atrophy
- the basal forebrain shows no structural abnormalities indicative of atrophy
- severe bilateral amygdala atrophy
- severe bilateral accumbens atrophy
- between mild and moderate bilateral pallidum atrophy
For the cerebral cortex:
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (severe) and central operculum (mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (moderate), medial frontal cortex (between mild and moderate), posterior orbital gyrus (between mild and moderate), subcallosal area (mild) and anterior orbital gyrus (between normal and mild)
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), planum polare (between moderate and severe), planum temporale (between normal and mild), inf. temporal gyrus (severe), middle temporal gyrus (severe), sup. temporal gyrus (mild) and temporal pole (severe)
- occipital lobe remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the parietal lobe
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (severe), anterior cingulate gyrus (between moderate and severe) and parahippocampal gyrus (between moderate and severe)
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- between normal and mild enlargement of the lateral ventricle
- no signs of enlargement detected in the 4th ventricle
- between normal and mild enlargement of the 3rd ventricle
- severe enlargement of the external csf | SV |
ADNI_127_S_4500_MR_Accelerated_Sag_IR-SPGR__br_raw_20120208145002226_92_S140206_I283521 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- between normal and mild bilateral putamen atrophy
- no evidence of atrophy or degeneration in the caudate
- accumbens presents with a healthy appearance, free from atrophy
- amygdala remains normal, with no signs of tissue loss
- no signs of atrophy detected in the hippocampus
- between mild and moderate bilateral thalamus atrophy
- severe bilateral ventral dc atrophy
- mild bilateral pallidum atrophy
- no observable atrophic alterations in the basal forebrain
For the ventricles:
- no enlargement observed in the external csf
- mild left enlargement of the inf. lateral ventricle
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- 4th ventricle appears structurally intact, with no evidence of enlargement
For the cerebral cortex:
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus medial segment (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (mild) and supplementary motor cortex (between normal and mild)
- no evidence of atrophy or degeneration in the temporal lobe
- occipital lobe presents with a healthy appearance, free from atrophy
- the insular cortex shows no structural abnormalities indicative of atrophy | AD |
ADNI_098_S_4002_MR_Accelerated_Sag_IR-SPGR__br_raw_20110301150635678_160_S100612_I221789 | On a T1-weighted brain MRI we observed:
For the ventricles:
- between mild and moderate enlargement of the external csf
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- no observable enlargement or abnormal growth in the 3rd ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
- no enlargement observed in the 4th ventricle
For the subcortical structures:
- mild bilateral accumbens atrophy
- pallidum remains normal, with no signs of tissue loss
- thalamus maintains its normal morphology without atrophic features
- between normal and mild right atrophy of the hippocampus
- putamen presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the caudate
- no evidence of atrophy or degeneration in the amygdala
- no observable atrophic alterations in the ventral dc
- no pathological changes consistent with atrophy detected in the basal forebrain
For the cerebral cortex:
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lateral orbital gyrus (between normal and mild), precentral gyrus medial segment (between normal and mild) and medial frontal cortex (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (mild)
- between mild and moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus (between normal and mild), postcentral gyrus medial segment (between normal and mild) and supramarginal gyrus (between normal and mild)
- the insular cortex shows no structural abnormalities indicative of atrophy
- mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (moderate) and sup. temporal gyrus (between normal and mild) | CN |
NIFD_1_S_0065_MR_t1_mprage_S3_DIS3D_br_raw_20111209104413296_6_S132363_I270815 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no signs of atrophy detected in the basal forebrain
- no observable atrophic alterations in the ventral dc
- between normal and mild left atrophy of the thalamus
- hippocampus remains normal, with no signs of tissue loss
- between normal and mild atrophy of the putamen
- mild atrophy of the pallidum
- between mild and moderate bilateral accumbens atrophy
- moderate bilateral caudate atrophy
- between normal and mild atrophy of the amygdala
For the cerebral cortex:
- between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (between mild and moderate) and parietal operculum (between mild and moderate)
- occipital lobe remains normal, with no signs of tissue loss
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus (between normal and mild)
- between mild and moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (between normal and mild) and middle frontal gyrus (severe)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (moderate), sup. temporal gyrus (mild) and transverse temporal gyrus (mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild) and middle cingulate gyrus (mild)
For the ventricles:
- mild bilateral lateral ventricle enlargement
- between mild and moderate enlargement of the external csf
- no pathological changes consistent with enlargement noted in the 4th ventricle
- severe bilateral inf. lateral ventricle enlargement
- severe enlargement of the 3rd ventricle | PNFA |
ADNI_006_S_4150_MR_MPRAGE_br_raw_20110809103032948_1_S117925_I249403 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no observable enlargement or abnormal growth in the 4th ventricle
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- no signs of enlargement detected in the lateral ventricle
- between normal and mild enlargement of the external csf
For the subcortical structures:
- accumbens appears structurally intact with no atrophic changes
- no observable atrophic alterations in the hippocampus
- no degenerative or atrophic changes noted in the amygdala
- no evidence of atrophy or degeneration in the thalamus
- basal forebrain appears structurally intact with no atrophic changes
- pallidum maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the ventral dc
- putamen remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the caudate
For the cerebral cortex:
- limbic cortex appears structurally intact with no atrophic changes
- no signs of atrophy detected in the parietal lobe
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in triangular inf. frontal gyrus (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (mild) and occipital fusiform gyrus (moderate)
- no degenerative or atrophic changes noted in the insular cortex
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (between mild and moderate) | CN |
NIFD_1_S_0106_MR_T1_mprage_S3_DIS3D_br_raw_20170815140458478_142_S595499_I888146 | On a T1-weighted brain MRI we observed:
For the ventricles:
- between normal and mild enlargement of the 3rd ventricle
- between mild and moderate bilateral lateral ventricle enlargement
- 4th ventricle maintains its normal volume without signs of enlargement
- between moderate and severe bilateral inf. lateral ventricle enlargement
- external csf maintains its normal volume without signs of enlargement
For the cerebral cortex:
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between normal and mild)
- temporal lobe remains normal, with no signs of tissue loss
- moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (mild), gyrus rectus (mild), medial frontal cortex (mild), middle frontal gyrus (between mild and moderate), lateral orbital gyrus (mild), precentral gyrus (between normal and mild), triangular inf. frontal gyrus (between normal and mild) and posterior orbital gyrus (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. parietal lobule (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (between normal and mild) and occipital pole (between normal and mild)
- between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (moderate)
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the caudate
- no signs of atrophy detected in the hippocampus
- no degenerative or atrophic changes noted in the accumbens
- basal forebrain maintains its normal morphology without atrophic features
- putamen maintains its normal morphology without atrophic features
- no observable atrophic alterations in the pallidum
- the amygdala shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the ventral dc
- no evidence of atrophy or degeneration in the thalamus | PNFA |
ADNI_073_S_4393_MR_MPRAGE_br_raw_20111122135347381_77_S130463_I268159 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (moderate) and sup. occipital gyrus (between normal and mild)
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: middle temporal gyrus (between normal and mild) and sup. temporal gyrus (between normal and mild)
- insular cortex remains normal, with no signs of tissue loss
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. frontal gyrus medial segment (mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in supramarginal gyrus (between normal and mild) and postcentral gyrus medial segment (between normal and mild)
For the ventricles:
- no observable enlargement or abnormal growth in the 3rd ventricle
- no signs of enlargement detected in the lateral ventricle
- no enlargement observed in the external csf
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- 4th ventricle maintains its normal volume without signs of enlargement
For the subcortical structures:
- mild bilateral basal forebrain atrophy
- amygdala maintains its normal morphology without atrophic features
- hippocampus remains normal, with no signs of tissue loss
- the pallidum shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the putamen
- no observable atrophic alterations in the accumbens
- ventral dc appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the caudate
- no pathological changes consistent with atrophy detected in the thalamus | CN |
ADNI_082_S_5184_MR_MPRAGE_br_raw_20130523103301800_81_S190368_I373616 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no observable enlargement or abnormal growth in the 3rd ventricle
- mild enlargement of the external csf
- no pathological changes consistent with enlargement noted in the lateral ventricle
- between normal and mild enlargement of the inf. lateral ventricle
- no observable enlargement or abnormal growth in the 4th ventricle
For the subcortical structures:
- thalamus maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the pallidum
- ventral dc appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the accumbens
- between mild and moderate bilateral amygdala atrophy
- no signs of atrophy detected in the caudate
- no degenerative or atrophic changes noted in the putamen
- no pathological changes consistent with atrophy detected in the basal forebrain
- between mild and moderate bilateral hippocampus atrophy
For the cerebral cortex:
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between normal and mild) and middle cingulate gyrus (between normal and mild)
- between mild and moderate atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (between normal and mild), middle temporal gyrus (between normal and mild) and sup. temporal gyrus (mild)
- occipital lobe appears structurally intact with no atrophic changes
- between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: medial frontal cortex (between normal and mild), sup. frontal gyrus (mild) and opercular inf. frontal gyrus (between normal and mild)
- no pathological changes consistent with atrophy detected in the insular cortex
- mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: angular gyrus (mild), postcentral gyrus medial segment (between normal and mild), precuneus (between normal and mild) and supramarginal gyrus (between normal and mild) | AD |
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