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CNADFTD-ADNI2NIFD-AN-fold-523-subtypes-2sigma-testset-T3RepXMRI-DNT-PNFA

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NIFD_1_S_0057_MR_t1_mprage_S3_DIS3D_br_raw_20110806171947495_144_S117779_I249202
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no signs of atrophy detected in the frontal lobe - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy on the left) and entorhinal area (mild atrophy on the left) - temporal lobe atrophy (mild-to-moderate on the left, normal on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left), middle temporal gyrus (mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left) and temporal pole (mild atrophy on the left) - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right) and inf. occipital gyrus (normal-to-mild atrophy on the left) - parietal lobe presents with a healthy appearance, free from atrophy - the insular cortex shows no structural abnormalities indicative of atrophy For the ventricles: - no signs of enlargement detected in the 4th ventricle - no abnormal enlargement observed in the external csf - 3rd ventricle appears structurally intact, with no evidence of enlargement - no abnormal enlargement observed in the lateral ventricle - inf. lateral ventricle enlargement (severe on the left, normal on the right) For the subcortical structures: - no observable atrophic alterations in the ventral dc - pallidum atrophy (normal-to-mild on the left, normal on the right) - putamen presents with a healthy appearance, free from atrophy - hippocampus atrophy (moderate on the left, normal-to-mild on the right) - basal forebrain remains normal, with no signs of tissue loss - no signs of atrophy detected in the caudate - accumbens atrophy (moderate-to-severe on the left, normal-to-mild on the right) - thalamus remains normal, with no signs of tissue loss - amygdala atrophy (severe on the left, normal on the right)
SV
ADNI_005_S_5038_MR_Accelerated_Sag_IR-SPGR__br_raw_20121213135711103_171_S177605_I351434
On a T1-weighted brain MRI we observed: For the ventricles: - no signs of enlargement detected in the external csf - no enlargement observed in the inf. lateral ventricle - 4th ventricle is free from enlargement or excessive growth - normal-to-mild bilateral lateral ventricle enlargement - normal-to-mild enlargement of the 3rd ventricle For the cerebral cortex: - no pathological changes consistent with atrophy detected in the parietal lobe - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (mild atrophy on the left) and temporal pole (normal-to-mild atrophy both left/right) - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the right) - no observable atrophic alterations in the frontal lobe - insular cortex presents with a healthy appearance, free from atrophy, with focal volume loss observed in the following subregions: frontal operculum (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left) - occipital lobe appears structurally intact with no atrophic changes For the subcortical structures: - putamen atrophy (normal-to-mild on the left, normal on the right) - basal forebrain maintains its normal morphology without atrophic features - amygdala atrophy (normal-to-mild on the left, mild on the right) - caudate atrophy (normal-to-mild on the left, normal on the right) - no evidence of atrophy or degeneration in the ventral dc - no observable atrophic alterations in the pallidum - accumbens atrophy (normal on the left, normal-to-mild on the right) - thalamus maintains its normal morphology without atrophic features - hippocampus atrophy (normal-to-mild on the left, normal on the right)
AD
NIFD_1_S_0251_MR_t1_mprage__br_raw_20160902173213372_55_S496003_I772210
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no pathological changes consistent with atrophy detected in the limbic cortex - insular cortex maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the temporal lobe - no pathological changes consistent with atrophy detected in the occipital lobe - frontal lobe maintains its normal morphology without atrophic features - parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: supramarginal gyrus (normal-to-mild atrophy both left/right) For the ventricles: - external csf remains within normal size parameters, with no enlargement detected - the 4th ventricle shows no structural abnormalities indicative of enlargement - no signs of enlargement detected in the 3rd ventricle - lateral ventricle remains within normal size parameters, with no enlargement detected - no signs of enlargement detected in the inf. lateral ventricle For the subcortical structures: - no evidence of atrophy or degeneration in the hippocampus - ventral dc appears structurally intact with no atrophic changes - basal forebrain presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the accumbens - no degenerative or atrophic changes noted in the putamen - pallidum appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the amygdala - no evidence of atrophy or degeneration in the thalamus - caudate presents with a healthy appearance, free from atrophy
CN
ADNI_072_S_4391_MR_MPRAGE_br_raw_20120110102851585_134_S135851_I276963
On a T1-weighted brain MRI we observed: For the cerebral cortex: - temporal lobe maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the insular cortex - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy on the right), posterior cingulate gyrus (normal-to-mild atrophy on the left) and anterior cingulate gyrus (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the frontal lobe - no evidence of atrophy or degeneration in the parietal lobe - no pathological changes consistent with atrophy detected in the occipital lobe For the subcortical structures: - no degenerative or atrophic changes noted in the putamen - pallidum remains normal, with no signs of tissue loss - accumbens remains normal, with no signs of tissue loss - hippocampus appears structurally intact with no atrophic changes - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - amygdala atrophy (normal on the left, normal-to-mild on the right) - no signs of atrophy detected in the ventral dc - no pathological changes consistent with atrophy detected in the caudate - thalamus appears structurally intact with no atrophic changes For the ventricles: - no observable enlargement or abnormal growth in the inf. lateral ventricle - no observable enlargement or abnormal growth in the 4th ventricle - no pathological changes consistent with enlargement noted in the lateral ventricle - the 3rd ventricle shows no structural abnormalities indicative of enlargement - external csf is free from enlargement or excessive growth
CN
ADNI_007_S_4516_MR_Accelerated_SAG_IR-SPGR__br_raw_20120213161211225_11_S140612_I284425
On a T1-weighted brain MRI we observed: For the cerebral cortex: - parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy both left/right) and angular gyrus (normal-to-mild atrophy on the right) - frontal lobe remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the temporal lobe - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (normal-to-mild atrophy on the left), middle occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and occipital fusiform gyrus (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the insular cortex - limbic cortex presents with a healthy appearance, free from atrophy For the ventricles: - lateral ventricle maintains its normal volume without signs of enlargement - the 4th ventricle shows no structural abnormalities indicative of enlargement - 3rd ventricle maintains its normal volume without signs of enlargement - no enlargement observed in the inf. lateral ventricle - normal-to-mild enlargement of the external csf For the subcortical structures: - accumbens appears structurally intact with no atrophic changes - thalamus atrophy (normal on the left, normal-to-mild on the right) - pallidum presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the basal forebrain - hippocampus appears structurally intact with no atrophic changes - the caudate shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the ventral dc - no observable atrophic alterations in the amygdala - putamen presents with a healthy appearance, free from atrophy
CN
ADNI_009_S_5037_MR_MPRAGE_br_raw_20130115124908317_109_S180207_I355099
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle maintains its normal volume without signs of enlargement - lateral ventricle enlargement (mild on the left, mild-to-moderate on the right) - inf. lateral ventricle enlargement (mild on the left, normal on the right) - 3rd ventricle maintains its normal volume without signs of enlargement - normal-to-mild enlargement of the external csf For the cerebral cortex: - no degenerative or atrophic changes noted in the frontal lobe - occipital lobe maintains its normal morphology without atrophic features - limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the right), parahippocampal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the left) - temporal lobe atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy on the left) and temporal pole (normal-to-mild atrophy on the left) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left) and central operculum (normal-to-mild atrophy on the left) - parietal lobe remains normal, with no signs of tissue loss For the subcortical structures: - caudate atrophy (mild-to-moderate on the left, mild on the right) - ventral dc atrophy (normal-to-mild on the left, mild on the right) - mild bilateral accumbens atrophy - mild bilateral thalamus atrophy - moderate bilateral pallidum atrophy - mild-to-moderate bilateral hippocampus atrophy - amygdala atrophy (severe on the left, moderate on the right) - moderate bilateral putamen atrophy - basal forebrain presents with a healthy appearance, free from atrophy
AD
NIFD_1_S_0304_MR_t1_mprage__br_raw_20160903225545116_69_S496975_I773325
On a T1-weighted brain MRI we observed: For the subcortical structures: - thalamus remains normal, with no signs of tissue loss - basal forebrain remains normal, with no signs of tissue loss - normal-to-mild bilateral putamen atrophy - pallidum appears structurally intact with no atrophic changes - no observable atrophic alterations in the hippocampus - caudate appears structurally intact with no atrophic changes - ventral dc presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the amygdala - accumbens atrophy (normal on the left, normal-to-mild on the right) For the cerebral cortex: - no observable atrophic alterations in the limbic cortex - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy on the right) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the left) and planum polare (normal-to-mild atrophy on the left) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy on the left) and posterior insula (normal-to-mild atrophy on the left) - frontal lobe remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the occipital lobe For the ventricles: - 4th ventricle remains within normal size parameters, with no enlargement detected - external csf maintains its normal volume without signs of enlargement - no enlargement observed in the lateral ventricle - inf. lateral ventricle is free from enlargement or excessive growth - normal-to-mild enlargement of the 3rd ventricle
CN
ADNI_137_S_4211_MR_MPRAGE_br_raw_20110921093358569_107_S122836_I257193
On a T1-weighted brain MRI we observed: For the subcortical structures: - no observable atrophic alterations in the thalamus - no observable atrophic alterations in the putamen - normal-to-mild bilateral amygdala atrophy - pallidum presents with a healthy appearance, free from atrophy - accumbens appears structurally intact with no atrophic changes - caudate presents with a healthy appearance, free from atrophy - basal forebrain appears structurally intact with no atrophic changes - hippocampus atrophy (normal on the left, normal-to-mild on the right) - no signs of atrophy detected in the ventral dc For the ventricles: - no enlargement observed in the 4th ventricle - no signs of enlargement detected in the inf. lateral ventricle - lateral ventricle appears structurally intact, with no evidence of enlargement - normal-to-mild enlargement of the external csf - the 3rd ventricle shows no structural abnormalities indicative of enlargement For the cerebral cortex: - parietal lobe remains normal, with no signs of tissue loss - occipital lobe remains normal, with no signs of tissue loss - the limbic cortex shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left) and medial frontal cortex (normal-to-mild atrophy on the right) - insular cortex appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the temporal lobe
AD
ADNI_037_S_4410_MR_MPRAGE_br_raw_20111221112623954_118_S134218_I273584
On a T1-weighted brain MRI we observed: For the ventricles: - external csf maintains its normal volume without signs of enlargement - 3rd ventricle remains within normal size parameters, with no enlargement detected - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - lateral ventricle maintains its normal volume without signs of enlargement - 4th ventricle maintains its normal volume without signs of enlargement For the cerebral cortex: - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the frontal lobe - occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: inf. occipital gyrus (normal-to-mild atrophy on the left), sup. occipital gyrus (normal-to-mild atrophy on the left) and lingual gyrus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the parietal lobe - no degenerative or atrophic changes noted in the temporal lobe - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the left) For the subcortical structures: - accumbens remains normal, with no signs of tissue loss - the hippocampus shows no structural abnormalities indicative of atrophy - pallidum maintains its normal morphology without atrophic features - caudate presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the thalamus - no evidence of atrophy or degeneration in the ventral dc - no signs of atrophy detected in the basal forebrain - amygdala atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral putamen atrophy
CN
ADNI_041_S_4037_MR_MPRAGE_br_raw_20110525095843682_27_S109767_I237027
On a T1-weighted brain MRI we observed: For the ventricles: - no signs of enlargement detected in the lateral ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - no pathological changes consistent with enlargement noted in the 3rd ventricle - no enlargement observed in the external csf - 4th ventricle is free from enlargement or excessive growth For the cerebral cortex: - no degenerative or atrophic changes noted in the limbic cortex - no observable atrophic alterations in the parietal lobe - no signs of atrophy detected in the frontal lobe - temporal lobe maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the insular cortex - occipital lobe remains normal, with no signs of tissue loss For the subcortical structures: - caudate remains normal, with no signs of tissue loss - hippocampus remains normal, with no signs of tissue loss - amygdala remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the putamen - no pathological changes consistent with atrophy detected in the basal forebrain - no evidence of atrophy or degeneration in the accumbens - ventral dc appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the pallidum - thalamus atrophy (normal on the left, normal-to-mild on the right)
CN
NIFD_2_S_0009_MR_MT1__GradWarp__N3m_Br_20111229190251842_S133685_I274732
On a T1-weighted brain MRI we observed: For the cerebral cortex: - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left), posterior insula (normal-to-mild atrophy on the left), central operculum (normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the occipital lobe - frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), medial frontal cortex (mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy on the left) and triangular inf. frontal gyrus (normal-to-mild atrophy on the left) - limbic cortex remains normal, with no signs of tissue loss - parietal lobe appears structurally intact with no atrophic changes - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. temporal gyrus (normal-to-mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy both left/right) and temporal pole (normal-to-mild atrophy on the right) For the ventricles: - mild enlargement of the 3rd ventricle - normal-to-mild enlargement of the external csf - no enlargement observed in the 4th ventricle - normal-to-mild bilateral inf. lateral ventricle enlargement - no signs of enlargement detected in the lateral ventricle For the subcortical structures: - amygdala atrophy (normal-to-mild on the left, normal on the right) - thalamus atrophy (mild-to-moderate on the left, normal-to-mild on the right) - the basal forebrain shows no structural abnormalities indicative of atrophy - ventral dc atrophy (mild on the left, normal-to-mild on the right) - accumbens atrophy (moderate on the left, mild-to-moderate on the right) - normal-to-mild bilateral hippocampus atrophy - putamen atrophy (mild on the left, normal on the right) - caudate atrophy (severe on the left, moderate-to-severe on the right) - pallidum atrophy (severe on the left, mild on the right)
BV
ADNI_068_S_4424_MR_MPRAGE_br_raw_20111223150836464_164_S134919_I274494
On a T1-weighted brain MRI we observed: For the ventricles: - no enlargement observed in the external csf - no abnormal enlargement observed in the inf. lateral ventricle - 4th ventricle is free from enlargement or excessive growth - 3rd ventricle appears structurally intact, with no evidence of enlargement - lateral ventricle appears structurally intact, with no evidence of enlargement For the cerebral cortex: - limbic cortex remains normal, with no signs of tissue loss - no signs of atrophy detected in the parietal lobe - temporal lobe remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the insular cortex - the frontal lobe shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the occipital lobe For the subcortical structures: - no observable atrophic alterations in the pallidum - no pathological changes consistent with atrophy detected in the ventral dc - basal forebrain atrophy (normal on the left, normal-to-mild on the right) - the putamen shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the hippocampus - amygdala maintains its normal morphology without atrophic features - no evidence of atrophy or degeneration in the accumbens - no observable atrophic alterations in the thalamus - caudate maintains its normal morphology without atrophic features
CN
NIFD_1_S_0140_MR_T1_mprage_S3_DIS3D_br_raw_20170817132248387_110_S598076_I891637
On a T1-weighted brain MRI we observed: For the subcortical structures: - mild bilateral pallidum atrophy - no observable atrophic alterations in the basal forebrain - normal-to-mild bilateral ventral dc atrophy - hippocampus atrophy (mild-to-moderate on the left, normal-to-mild on the right) - normal-to-mild bilateral caudate atrophy - accumbens atrophy (moderate on the left, normal-to-mild on the right) - putamen atrophy (mild-to-moderate on the left, normal-to-mild on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - severe bilateral amygdala atrophy For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - 3rd ventricle is free from enlargement or excessive growth - severe bilateral inf. lateral ventricle enlargement - no observable enlargement or abnormal growth in the lateral ventricle - normal-to-mild enlargement of the external csf For the cerebral cortex: - no observable atrophic alterations in the parietal lobe - no evidence of atrophy or degeneration in the occipital lobe - temporal lobe atrophy (severe on the left, moderate on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), planum polare (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy both left/right) and temporal pole (severe atrophy on the left and moderate atrophy on the right) - limbic cortex atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left) and posterior insula (normal-to-mild atrophy both left/right) - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) and orbital inf. frontal gyrus (normal-to-mild atrophy on the left)
SV
NIFD_1_S_0341_MR_T1_mprage_S3_DIS3D_br_raw_20170629011553917_19_S577938_I867720
On a T1-weighted brain MRI we observed: For the ventricles: - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - 3rd ventricle is free from enlargement or excessive growth - mild enlargement of the external csf - 4th ventricle is free from enlargement or excessive growth - inf. lateral ventricle enlargement (severe on the left, normal on the right) For the subcortical structures: - no evidence of atrophy or degeneration in the basal forebrain - amygdala atrophy (severe on the left, normal on the right) - no evidence of atrophy or degeneration in the hippocampus - caudate atrophy (severe on the left, normal-to-mild on the right) - ventral dc presents with a healthy appearance, free from atrophy - accumbens atrophy (severe on the left, mild on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - putamen atrophy (severe on the left, normal-to-mild on the right) - pallidum atrophy (mild on the left, normal on the right) For the cerebral cortex: - insular cortex atrophy (mild-to-moderate on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate-to-severe atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and mild atrophy on the right) and posterior insula (normal-to-mild atrophy on the left) - limbic cortex atrophy (mild-to-moderate on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and entorhinal area (normal-to-mild atrophy on the left) - no observable atrophic alterations in the occipital lobe - frontal lobe atrophy (severe on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (mild atrophy on the left), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy both left/right), middle frontal gyrus (moderate atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (mild atrophy on the left), posterior orbital gyrus (mild atrophy both left/right), sup. frontal gyrus (moderate-to-severe atrophy on the left), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the left) - parietal lobe appears structurally intact with no atrophic changes - temporal lobe appears structurally intact with no atrophic changes, with focal volume loss observed in the following subregions: planum polare (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left) and temporal pole (mild atrophy on the left)
PNFA
NIFD_1_S_0026_MR_t1_mprage_S3_DIS3D_br_raw_20110412101938141_66_S103861_I227149
On a T1-weighted brain MRI we observed: For the cerebral cortex: - severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), planum polare (normal-to-mild atrophy on the left and moderate-to-severe atrophy on the right), planum temporale (normal-to-mild atrophy on the left), inf. temporal gyrus (moderate atrophy both left/right), middle temporal gyrus (moderate atrophy on the left and severe atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy both left/right) and temporal pole (moderate-to-severe atrophy on the left and severe atrophy on the right) - no evidence of atrophy or degeneration in the occipital lobe - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) - insular cortex atrophy (moderate on the left, severe on the right), with focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), posterior insula (mild atrophy on the left and severe atrophy on the right), central operculum (normal-to-mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the right) - no evidence of atrophy or degeneration in the parietal lobe - mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy both left/right), anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (mild atrophy both left/right) For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - moderate enlargement of the external csf - severe bilateral inf. lateral ventricle enlargement - lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - 4th ventricle appears structurally intact, with no evidence of enlargement For the subcortical structures: - severe bilateral amygdala atrophy - hippocampus atrophy (mild-to-moderate on the left, severe on the right) - putamen atrophy (moderate-to-severe on the left, severe on the right) - basal forebrain maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the ventral dc - thalamus atrophy (normal on the left, normal-to-mild on the right) - caudate atrophy (mild on the left, severe on the right) - accumbens atrophy (moderate-to-severe on the left, severe on the right) - pallidum atrophy (normal-to-mild on the left, mild on the right)
SV
NIFD_1_S_0128_MR_T1_mprage_S5_DIS3D_br_raw_20170817092725939_46_S597144_I890396
On a T1-weighted brain MRI we observed: For the cerebral cortex: - frontal lobe atrophy (severe on the left, mild on the right), with focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the right), middle frontal gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild atrophy on the left), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right) and triangular inf. frontal gyrus (normal-to-mild atrophy on the left) - temporal lobe atrophy (severe on the left, normal on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left), inf. temporal gyrus (mild atrophy on the left), middle temporal gyrus (moderate atrophy on the left), sup. temporal gyrus (normal-to-mild atrophy on the left) and temporal pole (mild atrophy on the left) - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left) and precuneus (normal-to-mild atrophy on the left) - occipital lobe presents with a healthy appearance, free from atrophy - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the left), parahippocampal gyrus (normal-to-mild atrophy on the left) and anterior cingulate gyrus (normal-to-mild atrophy on the left) - insular cortex remains normal, with no signs of tissue loss, with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the left) For the ventricles: - 3rd ventricle appears structurally intact, with no evidence of enlargement - lateral ventricle enlargement (mild on the left, normal on the right) - inf. lateral ventricle enlargement (severe on the left, normal-to-mild on the right) - no enlargement observed in the 4th ventricle - mild enlargement of the external csf For the subcortical structures: - thalamus atrophy (normal-to-mild on the left, normal on the right) - caudate atrophy (mild-to-moderate on the left, normal-to-mild on the right) - accumbens atrophy (mild on the left, normal on the right) - no degenerative or atrophic changes noted in the ventral dc - hippocampus atrophy (mild on the left, normal-to-mild on the right) - pallidum remains normal, with no signs of tissue loss - amygdala atrophy (moderate on the left, normal-to-mild on the right) - no degenerative or atrophic changes noted in the basal forebrain - putamen atrophy (mild on the left, normal on the right)
PNFA
ADNI_031_S_4021_MR_MPRAGE_br_raw_20110426184122527_37_S105268_I229148
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evidence of atrophy or degeneration in the hippocampus - no observable atrophic alterations in the ventral dc - no evidence of atrophy or degeneration in the thalamus - no evidence of atrophy or degeneration in the putamen - amygdala remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the accumbens - caudate maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the pallidum - basal forebrain remains normal, with no signs of tissue loss For the ventricles: - no pathological changes consistent with enlargement noted in the external csf - normal-to-mild enlargement of the 3rd ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - 4th ventricle maintains its normal volume without signs of enlargement - normal-to-mild bilateral lateral ventricle enlargement For the cerebral cortex: - the occipital lobe shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the insular cortex - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy on the left), precuneus (normal-to-mild atrophy both left/right), angular gyrus (normal-to-mild atrophy on the right) and supramarginal gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the temporal lobe - the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the left)
CN
NIFD_2_S_0016_MR_MT1__GradWarp__N3m_Br_20130131161214414_S180124_I357405
On a T1-weighted brain MRI we observed: For the subcortical structures: - putamen atrophy (moderate-to-severe on the left, severe on the right) - pallidum atrophy (normal-to-mild on the left, moderate on the right) - caudate atrophy (mild on the left, severe on the right) - thalamus atrophy (normal on the left, mild on the right) - basal forebrain appears structurally intact with no atrophic changes - hippocampus atrophy (normal on the left, moderate on the right) - ventral dc atrophy (normal-to-mild on the left, normal on the right) - amygdala atrophy (moderate-to-severe on the left, severe on the right) - severe bilateral accumbens atrophy For the cerebral cortex: - the occipital lobe shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the parietal lobe - insular cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), frontal operculum (normal-to-mild atrophy on the right) and posterior insula (normal-to-mild atrophy on the right) - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) and entorhinal area (mild atrophy on the right) - temporal lobe atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the right), transverse temporal gyrus (normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the right) - frontal lobe atrophy (normal on the left, moderate-to-severe on the right), with focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and moderate-to-severe atrophy on the right), medial frontal cortex (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the right) For the ventricles: - 4th ventricle appears structurally intact, with no evidence of enlargement - normal-to-mild bilateral lateral ventricle enlargement - inf. lateral ventricle enlargement (normal-to-mild on the left, severe on the right) - mild enlargement of the external csf - mild enlargement of the 3rd ventricle
BV
NIFD_1_S_0161_MR_T1_mprage_S3_DIS3D_br_raw_20140630121148243_153_S223484_I433506
On a T1-weighted brain MRI we observed: For the cerebral cortex: - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), parietal operculum (mild atrophy on the right) and posterior insula (normal-to-mild atrophy on the left) - temporal lobe appears structurally intact with no atrophic changes - limbic cortex presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the occipital lobe - parietal lobe atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy on the left), sup. parietal lobule (normal-to-mild atrophy on the right), supramarginal gyrus (normal-to-mild atrophy on the left) and postcentral gyrus medial segment (normal-to-mild atrophy on the left) - no signs of atrophy detected in the frontal lobe For the ventricles: - no signs of enlargement detected in the 3rd ventricle - inf. lateral ventricle is free from enlargement or excessive growth - mild enlargement of the 4th ventricle - lateral ventricle remains within normal size parameters, with no enlargement detected - external csf is free from enlargement or excessive growth For the subcortical structures: - no signs of atrophy detected in the putamen - no degenerative or atrophic changes noted in the caudate - hippocampus presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the thalamus - accumbens atrophy (normal on the left, normal-to-mild on the right) - the basal forebrain shows no structural abnormalities indicative of atrophy - the pallidum shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the ventral dc - amygdala remains normal, with no signs of tissue loss
CN
NIFD_1_S_0199_MR_T1_mprage_S3_DIS3D_br_raw_20140901083527059_106_S229356_I441709
On a T1-weighted brain MRI we observed: For the subcortical structures: - no evidence of atrophy or degeneration in the hippocampus - pallidum remains normal, with no signs of tissue loss - no signs of atrophy detected in the caudate - no observable atrophic alterations in the amygdala - ventral dc remains normal, with no signs of tissue loss - accumbens maintains its normal morphology without atrophic features - thalamus maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the putamen - no signs of atrophy detected in the basal forebrain For the ventricles: - no observable enlargement or abnormal growth in the 3rd ventricle - external csf appears structurally intact, with no evidence of enlargement - no abnormal enlargement observed in the inf. lateral ventricle - no pathological changes consistent with enlargement noted in the 4th ventricle - no signs of enlargement detected in the lateral ventricle For the cerebral cortex: - no evidence of atrophy or degeneration in the temporal lobe - limbic cortex appears structurally intact with no atrophic changes - no observable atrophic alterations in the frontal lobe - no degenerative or atrophic changes noted in the insular cortex - no evidence of atrophy or degeneration in the parietal lobe - occipital lobe maintains its normal morphology without atrophic features
PNFA
ADNI_116_S_4537_MR_MPRAGE_br_raw_20120217123755224_132_S141133_I285465
On a T1-weighted brain MRI we observed: For the cerebral cortex: - frontal lobe atrophy (mild-to-moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left), middle frontal gyrus (mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the left) and lateral orbital gyrus (normal-to-mild atrophy on the left) - insular cortex atrophy (mild-to-moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy both left/right) - temporal lobe atrophy (moderate-to-severe on the left, mild on the right), with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy on the left), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the left), temporal pole (normal-to-mild atrophy on the right) and fusiform gyrus (normal-to-mild atrophy on the left) - no pathological changes consistent with atrophy detected in the limbic cortex - the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (mild atrophy on the left) - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: cuneus (normal-to-mild atrophy on the left), lingual gyrus (normal-to-mild atrophy on the right) and middle occipital gyrus (normal-to-mild atrophy on the right) For the ventricles: - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - mild enlargement of the external csf - inf. lateral ventricle maintains its normal volume without signs of enlargement - no signs of enlargement detected in the 3rd ventricle - 4th ventricle remains within normal size parameters, with no enlargement detected For the subcortical structures: - accumbens atrophy (mild on the left, normal-to-mild on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - caudate atrophy (mild on the left, normal-to-mild on the right) - basal forebrain presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the ventral dc - putamen atrophy (normal-to-mild on the left, normal on the right) - the pallidum shows no structural abnormalities indicative of atrophy - amygdala atrophy (mild on the left, normal-to-mild on the right) - hippocampus presents with a healthy appearance, free from atrophy
AD
NIFD_1_S_0150_MR_T1_mprage_S3_DIS3D_br_raw_20140612230525878_108_S222089_I430659
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no observable atrophic alterations in the parietal lobe - no observable atrophic alterations in the occipital lobe - no signs of atrophy detected in the frontal lobe - no evidence of atrophy or degeneration in the insular cortex - no degenerative or atrophic changes noted in the temporal lobe - limbic cortex appears structurally intact with no atrophic changes For the ventricles: - 3rd ventricle remains within normal size parameters, with no enlargement detected - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - 4th ventricle remains within normal size parameters, with no enlargement detected - external csf remains within normal size parameters, with no enlargement detected - no signs of enlargement detected in the lateral ventricle For the subcortical structures: - basal forebrain remains normal, with no signs of tissue loss - ventral dc remains normal, with no signs of tissue loss - amygdala presents with a healthy appearance, free from atrophy - caudate atrophy (normal-to-mild on the left, normal on the right) - hippocampus remains normal, with no signs of tissue loss - accumbens appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the putamen - pallidum presents with a healthy appearance, free from atrophy - the thalamus shows no structural abnormalities indicative of atrophy
CN
NIFD_1_S_0268_MR_t1_mprage__br_raw_20160902215549629_32_S496395_I772656
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc atrophy (normal-to-mild on the left, normal on the right) - amygdala maintains its normal morphology without atrophic features - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral pallidum atrophy - no degenerative or atrophic changes noted in the hippocampus - normal-to-mild bilateral putamen atrophy - basal forebrain maintains its normal morphology without atrophic features - no observable atrophic alterations in the thalamus - caudate atrophy (normal on the left, normal-to-mild on the right) For the cerebral cortex: - normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), sup. occipital gyrus (normal-to-mild atrophy on the left), occipital pole (normal-to-mild atrophy both left/right) and middle occipital gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the temporal lobe - no pathological changes consistent with atrophy detected in the insular cortex - frontal lobe appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the limbic cortex - parietal lobe maintains its normal morphology without atrophic features For the ventricles: - no signs of enlargement detected in the 3rd ventricle - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - lateral ventricle appears structurally intact, with no evidence of enlargement - no abnormal enlargement observed in the 4th ventricle - normal-to-mild enlargement of the external csf
CN
ADNI_016_S_4353_MR_Accelerated_SAG_IR-SPGR__br_raw_20111122093825556_165_S130365_I267942
On a T1-weighted brain MRI we observed: For the subcortical structures: - the putamen shows no structural abnormalities indicative of atrophy - normal-to-mild bilateral accumbens atrophy - basal forebrain appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the ventral dc - no signs of atrophy detected in the thalamus - no observable atrophic alterations in the pallidum - normal-to-mild bilateral caudate atrophy - amygdala atrophy (normal on the left, normal-to-mild on the right) - no degenerative or atrophic changes noted in the hippocampus For the cerebral cortex: - no evidence of atrophy or degeneration in the insular cortex - no signs of atrophy detected in the occipital lobe - no pathological changes consistent with atrophy detected in the limbic cortex - no signs of atrophy detected in the frontal lobe - parietal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. parietal lobule (normal-to-mild atrophy on the right), supramarginal gyrus (normal-to-mild atrophy on the right) and postcentral gyrus medial segment (normal-to-mild atrophy on the right) - temporal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the right), temporal pole (normal-to-mild atrophy both left/right) and middle temporal gyrus (normal-to-mild atrophy on the right) For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - normal-to-mild enlargement of the external csf - mild enlargement of the 3rd ventricle - normal-to-mild bilateral lateral ventricle enlargement
AD
NIFD_1_S_0049_MR_T1_mprage_S3_DIS3D_br_raw_20170816152803397_39_S596484_I889453
On a T1-weighted brain MRI we observed: For the subcortical structures: - no pathological changes consistent with atrophy detected in the amygdala - accumbens atrophy (normal-to-mild on the left, normal on the right) - thalamus maintains its normal morphology without atrophic features - no signs of atrophy detected in the basal forebrain - hippocampus remains normal, with no signs of tissue loss - no observable atrophic alterations in the caudate - no degenerative or atrophic changes noted in the pallidum - no evidence of atrophy or degeneration in the putamen - the ventral dc shows no structural abnormalities indicative of atrophy For the ventricles: - external csf maintains its normal volume without signs of enlargement - no observable enlargement or abnormal growth in the 3rd ventricle - lateral ventricle remains within normal size parameters, with no enlargement detected - the 4th ventricle shows no structural abnormalities indicative of enlargement - inf. lateral ventricle maintains its normal volume without signs of enlargement For the cerebral cortex: - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (normal-to-mild atrophy both left/right) and precentral gyrus (mild atrophy on the right) - insular cortex appears structurally intact with no atrophic changes - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle occipital gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), calcarine cortex (normal-to-mild atrophy on the right) and lingual gyrus (mild atrophy on the right) - no degenerative or atrophic changes noted in the temporal lobe - no evidence of atrophy or degeneration in the limbic cortex - no observable atrophic alterations in the parietal lobe
CN
ADNI_037_S_4308_MR_MPRAGE_br_raw_20120220143010051_150_S141242_I285690
On a T1-weighted brain MRI we observed: For the cerebral cortex: - insular cortex appears structurally intact with no atrophic changes - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lingual gyrus (normal-to-mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy on the right) and sup. occipital gyrus (mild atrophy on the left) - no degenerative or atrophic changes noted in the temporal lobe - no evidence of atrophy or degeneration in the limbic cortex - no signs of atrophy detected in the frontal lobe - parietal lobe appears structurally intact with no atrophic changes For the ventricles: - external csf appears structurally intact, with no evidence of enlargement - no signs of enlargement detected in the 3rd ventricle - inf. lateral ventricle maintains its normal volume without signs of enlargement - the 4th ventricle shows no structural abnormalities indicative of enlargement - lateral ventricle remains within normal size parameters, with no enlargement detected For the subcortical structures: - the thalamus shows no structural abnormalities indicative of atrophy - caudate remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the basal forebrain - pallidum atrophy (normal on the left, normal-to-mild on the right) - the ventral dc shows no structural abnormalities indicative of atrophy - hippocampus remains normal, with no signs of tissue loss - amygdala maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the accumbens - no observable atrophic alterations in the putamen
CN
NIFD_2_S_0019_MR_MT1__GradWarp__N3m_Br_20120706160105603_S156754_I315305
On a T1-weighted brain MRI we observed: For the ventricles: - mild-to-moderate enlargement of the 3rd ventricle - the external csf shows no structural abnormalities indicative of enlargement - no abnormal enlargement observed in the 4th ventricle - lateral ventricle enlargement (mild-to-moderate on the left, severe on the right) - severe bilateral inf. lateral ventricle enlargement For the cerebral cortex: - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left), anterior cingulate gyrus (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (mild atrophy on the left) - no pathological changes consistent with atrophy detected in the occipital lobe - the parietal lobe shows no structural abnormalities indicative of atrophy - temporal lobe remains normal, with no signs of tissue loss - frontal lobe atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: triangular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the right) and posterior orbital gyrus (normal-to-mild atrophy on the right) - insular cortex atrophy (normal on the left, moderate on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (normal-to-mild atrophy on the right), central operculum (mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the right) For the subcortical structures: - ventral dc atrophy (normal-to-mild on the left, mild on the right) - severe bilateral accumbens atrophy - hippocampus atrophy (severe on the left, moderate-to-severe on the right) - thalamus atrophy (normal-to-mild on the left, mild-to-moderate on the right) - pallidum atrophy (moderate on the left, severe on the right) - caudate atrophy (moderate-to-severe on the left, severe on the right) - no degenerative or atrophic changes noted in the basal forebrain - amygdala atrophy (severe on the left, mild on the right) - severe bilateral putamen atrophy
BV
ADNI_006_S_4150_MR_MPRAGE_br_raw_20110809103032948_1_S117925_I249403
On a T1-weighted brain MRI we observed: For the ventricles: - 3rd ventricle is free from enlargement or excessive growth - no enlargement observed in the inf. lateral ventricle - no pathological changes consistent with enlargement noted in the lateral ventricle - normal-to-mild enlargement of the external csf - no observable enlargement or abnormal growth in the 4th ventricle For the cerebral cortex: - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left) and anterior cingulate gyrus (normal-to-mild atrophy on the right) - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (normal-to-mild atrophy on the right) and occipital fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - temporal lobe remains normal, with no signs of tissue loss - no signs of atrophy detected in the parietal lobe - no evidence of atrophy or degeneration in the frontal lobe - no signs of atrophy detected in the insular cortex For the subcortical structures: - hippocampus appears structurally intact with no atrophic changes - the thalamus shows no structural abnormalities indicative of atrophy - accumbens maintains its normal morphology without atrophic features - no signs of atrophy detected in the caudate - amygdala maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the ventral dc - no evidence of atrophy or degeneration in the putamen - basal forebrain presents with a healthy appearance, free from atrophy - the pallidum shows no structural abnormalities indicative of atrophy
CN
NIFD_1_S_0006_MR_t1_mprage_S17_DIS3D__br_raw_20110209084502271_56_S99257_I216358
On a T1-weighted brain MRI we observed: For the subcortical structures: - hippocampus maintains its normal morphology without atrophic features - thalamus atrophy (moderate on the left, normal on the right) - amygdala atrophy (normal-to-mild on the left, normal on the right) - pallidum atrophy (moderate on the left, normal-to-mild on the right) - the basal forebrain shows no structural abnormalities indicative of atrophy - caudate atrophy (moderate-to-severe on the left, mild on the right) - putamen atrophy (moderate-to-severe on the left, normal-to-mild on the right) - accumbens atrophy (mild on the left, normal-to-mild on the right) - no degenerative or atrophic changes noted in the ventral dc For the ventricles: - inf. lateral ventricle enlargement (moderate-to-severe on the left, normal on the right) - mild enlargement of the external csf - normal-to-mild bilateral lateral ventricle enlargement - mild enlargement of the 3rd ventricle - normal-to-mild enlargement of the 4th ventricle For the cerebral cortex: - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy both left/right) and temporal pole (normal-to-mild atrophy on the right) - frontal lobe atrophy (moderate-to-severe on the left, mild on the right), with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left) and precentral gyrus medial segment (normal-to-mild atrophy on the left) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: frontal operculum (normal-to-mild atrophy both left/right) and central operculum (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the occipital lobe - limbic cortex appears structurally intact with no atrophic changes - parietal lobe remains normal, with no signs of tissue loss
BV
NIFD_1_S_0277_MR_t1_mprage__br_raw_20160903201332611_41_S496668_I772969
On a T1-weighted brain MRI we observed: For the ventricles: - lateral ventricle is free from enlargement or excessive growth - external csf remains within normal size parameters, with no enlargement detected - no signs of enlargement detected in the 4th ventricle - 3rd ventricle maintains its normal volume without signs of enlargement - no abnormal enlargement observed in the inf. lateral ventricle For the cerebral cortex: - no signs of atrophy detected in the limbic cortex - no pathological changes consistent with atrophy detected in the temporal lobe - occipital lobe remains normal, with no signs of tissue loss - parietal lobe maintains its normal morphology without atrophic features - insular cortex remains normal, with no signs of tissue loss - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy both left/right) and supplementary motor cortex (normal-to-mild atrophy on the left) For the subcortical structures: - no signs of atrophy detected in the amygdala - no degenerative or atrophic changes noted in the caudate - pallidum presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the thalamus - no signs of atrophy detected in the hippocampus - accumbens atrophy (normal-to-mild on the left, normal on the right) - no pathological changes consistent with atrophy detected in the basal forebrain - no degenerative or atrophic changes noted in the ventral dc - putamen maintains its normal morphology without atrophic features
CN
NIFD_1_S_0034_MR_t1_mprage_S3_DIS3D_br_raw_20110428012718005_13_S105419_I229382
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no evidence of atrophy or degeneration in the parietal lobe - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: orbital inf. frontal gyrus (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left) and supplementary motor cortex (normal-to-mild atrophy on the left) - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy on the left) - no observable atrophic alterations in the occipital lobe - temporal lobe appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the limbic cortex For the subcortical structures: - pallidum appears structurally intact with no atrophic changes - caudate maintains its normal morphology without atrophic features - no evidence of atrophy or degeneration in the putamen - the amygdala shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the thalamus - no observable atrophic alterations in the hippocampus - accumbens atrophy (normal-to-mild on the left, normal on the right) - basal forebrain remains normal, with no signs of tissue loss - ventral dc presents with a healthy appearance, free from atrophy For the ventricles: - mild enlargement of the 3rd ventricle - no abnormal enlargement observed in the external csf - normal-to-mild bilateral lateral ventricle enlargement - no observable enlargement or abnormal growth in the 4th ventricle - inf. lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
CN
NIFD_1_S_0147_MR_T1_mprage_S3_DIS3D_br_raw_20140612224636364_53_S222067_I430635
On a T1-weighted brain MRI we observed: For the ventricles: - external csf maintains its normal volume without signs of enlargement - no pathological changes consistent with enlargement noted in the 4th ventricle - lateral ventricle is free from enlargement or excessive growth - no abnormal enlargement observed in the inf. lateral ventricle - 3rd ventricle is free from enlargement or excessive growth For the cerebral cortex: - parietal lobe presents with a healthy appearance, free from atrophy - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the right) and fusiform gyrus (normal-to-mild atrophy on the left) - frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the left) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left) and frontal operculum (normal-to-mild atrophy on the left) - occipital lobe appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the limbic cortex For the subcortical structures: - pallidum atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral accumbens atrophy - ventral dc remains normal, with no signs of tissue loss - the hippocampus shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the thalamus - amygdala maintains its normal morphology without atrophic features - putamen presents with a healthy appearance, free from atrophy - basal forebrain appears structurally intact with no atrophic changes - caudate atrophy (normal on the left, normal-to-mild on the right)
PNFA
NIFD_1_S_0107_MR_T1_mprage_S3_DIS3D_br_raw_20121011130541426_81_S170553_I339670
On a T1-weighted brain MRI we observed: For the subcortical structures: - no signs of atrophy detected in the amygdala - hippocampus presents with a healthy appearance, free from atrophy - the thalamus shows no structural abnormalities indicative of atrophy - ventral dc maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the caudate - the putamen shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the accumbens - pallidum remains normal, with no signs of tissue loss - no signs of atrophy detected in the basal forebrain For the cerebral cortex: - frontal lobe presents with a healthy appearance, free from atrophy - insular cortex maintains its normal morphology without atrophic features - temporal lobe remains normal, with no signs of tissue loss - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - parietal lobe maintains its normal morphology without atrophic features - no evidence of atrophy or degeneration in the occipital lobe For the ventricles: - the external csf shows no structural abnormalities indicative of enlargement - no signs of enlargement detected in the 4th ventricle - no pathological changes consistent with enlargement noted in the 3rd ventricle - lateral ventricle remains within normal size parameters, with no enlargement detected - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
CN
ADNI_031_S_4496_MR_MPRAGE_br_raw_20120203142353809_150_S139647_I282638
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement or abnormal growth in the 4th ventricle - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - no observable enlargement or abnormal growth in the lateral ventricle - no abnormal enlargement observed in the 3rd ventricle - normal-to-mild enlargement of the external csf For the subcortical structures: - the basal forebrain shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the hippocampus - pallidum atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral caudate atrophy - ventral dc atrophy (normal on the left, normal-to-mild on the right) - thalamus presents with a healthy appearance, free from atrophy - normal-to-mild bilateral accumbens atrophy - putamen atrophy (normal-to-mild on the left, normal on the right) - amygdala maintains its normal morphology without atrophic features For the cerebral cortex: - normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: lingual gyrus (normal-to-mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy on the right), middle occipital gyrus (normal-to-mild atrophy both left/right) and occipital pole (normal-to-mild atrophy on the right) - no pathological changes consistent with atrophy detected in the temporal lobe - limbic cortex presents with a healthy appearance, free from atrophy - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the right) - no pathological changes consistent with atrophy detected in the frontal lobe - insular cortex presents with a healthy appearance, free from atrophy
CN
ADNI_127_S_5058_MR_Accelerated_Sag_IR-FSPGR_br_raw_20130110155435101_67_S179905_I354645
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no observable atrophic alterations in the temporal lobe - no observable atrophic alterations in the limbic cortex - parietal lobe atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: sup. parietal lobule (normal-to-mild atrophy on the right), angular gyrus (mild atrophy on the right) and precuneus (mild atrophy on the right) - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: lingual gyrus (normal-to-mild atrophy on the left) and occipital fusiform gyrus (normal-to-mild atrophy on the right) - insular cortex remains normal, with no signs of tissue loss - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the left) and triangular inf. frontal gyrus (mild atrophy on the left) For the ventricles: - no enlargement observed in the lateral ventricle - normal-to-mild enlargement of the 3rd ventricle - 4th ventricle maintains its normal volume without signs of enlargement - inf. lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild enlargement of the external csf For the subcortical structures: - no degenerative or atrophic changes noted in the amygdala - caudate atrophy (normal on the left, normal-to-mild on the right) - no degenerative or atrophic changes noted in the thalamus - pallidum presents with a healthy appearance, free from atrophy - hippocampus appears structurally intact with no atrophic changes - accumbens atrophy (normal-to-mild on the left, mild on the right) - basal forebrain appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the ventral dc - normal-to-mild bilateral putamen atrophy
AD
ADNI_003_S_4373_MR_Accelerated_SAG_IR-SPGR__br_raw_20111227095734176_117_S134978_I274607
On a T1-weighted brain MRI we observed: For the cerebral cortex: - occipital lobe presents with a healthy appearance, free from atrophy - temporal lobe atrophy (moderate-to-severe on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left), inf. temporal gyrus (mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the left) and temporal pole (normal-to-mild atrophy on the left) - limbic cortex atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate-to-severe atrophy on the left and mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the right), posterior cingulate gyrus (mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left) - parietal lobe atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), precuneus (moderate atrophy both left/right), sup. parietal lobule (normal-to-mild atrophy on the left), postcentral gyrus (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the right) - frontal lobe atrophy (mild-to-moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the left), gyrus rectus (normal-to-mild atrophy on the left) and precentral gyrus medial segment (mild atrophy on the left) - insular cortex atrophy (mild-to-moderate on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), parietal operculum (normal-to-mild atrophy on the left) and frontal operculum (normal-to-mild atrophy on the right) For the ventricles: - 3rd ventricle appears structurally intact, with no evidence of enlargement - severe enlargement of the external csf - lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - no enlargement observed in the 4th ventricle - inf. lateral ventricle enlargement (moderate on the left, moderate-to-severe on the right) For the subcortical structures: - no signs of atrophy detected in the hippocampus - amygdala atrophy (moderate on the left, mild on the right) - moderate bilateral accumbens atrophy - pallidum atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the thalamus - ventral dc appears structurally intact with no atrophic changes - basal forebrain remains normal, with no signs of tissue loss - putamen atrophy (mild-to-moderate on the left, normal-to-mild on the right) - mild bilateral caudate atrophy
AD
NIFD_1_S_0312_MR_t1_mprage_S3_DIS3D_br_raw_20160909141655212_27_S498027_I774594
On a T1-weighted brain MRI we observed: For the ventricles: - no pathological changes consistent with enlargement noted in the inf. lateral ventricle - no signs of enlargement detected in the 4th ventricle - 3rd ventricle maintains its normal volume without signs of enlargement - lateral ventricle is free from enlargement or excessive growth - normal-to-mild enlargement of the external csf For the subcortical structures: - accumbens atrophy (normal on the left, normal-to-mild on the right) - no signs of atrophy detected in the hippocampus - no pathological changes consistent with atrophy detected in the pallidum - no evidence of atrophy or degeneration in the ventral dc - putamen appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the basal forebrain - thalamus maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the caudate - no evidence of atrophy or degeneration in the amygdala For the cerebral cortex: - insular cortex appears structurally intact with no atrophic changes - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: inf. occipital gyrus (normal-to-mild atrophy on the right) and occipital fusiform gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: orbital inf. frontal gyrus (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right), supplementary motor cortex (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) - parietal lobe presents with a healthy appearance, free from atrophy - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the right), temporal pole (normal-to-mild atrophy both left/right) and transverse temporal gyrus (normal-to-mild atrophy on the right) - limbic cortex remains normal, with no signs of tissue loss, with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left)
CN
ADNI_003_S_5165_MR_Accelerated_SAG_IR-SPGR__br_raw_20130520154957012_180_S190116_I373251
On a T1-weighted brain MRI we observed: For the subcortical structures: - amygdala remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the basal forebrain - no observable atrophic alterations in the ventral dc - no degenerative or atrophic changes noted in the caudate - no degenerative or atrophic changes noted in the pallidum - thalamus appears structurally intact with no atrophic changes - normal-to-mild bilateral putamen atrophy - hippocampus atrophy (normal on the left, normal-to-mild on the right) - accumbens atrophy (normal-to-mild on the left, normal on the right) For the ventricles: - no enlargement observed in the external csf - normal-to-mild enlargement of the 4th ventricle - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) For the cerebral cortex: - occipital lobe remains normal, with no signs of tissue loss - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy on the left) and entorhinal area (normal-to-mild atrophy on the right) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), posterior insula (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left) - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy on the right) and planum temporale (normal-to-mild atrophy on the right) - the frontal lobe shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the parietal lobe
AD
ADNI_094_S_4459_MR_Accelerated_SAG_IR-SPGR__br_raw_20120222110144176_106_S140152_I283439
On a T1-weighted brain MRI we observed: For the ventricles: - external csf is free from enlargement or excessive growth - no observable enlargement or abnormal growth in the 3rd ventricle - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the 4th ventricle - lateral ventricle remains within normal size parameters, with no enlargement detected For the cerebral cortex: - limbic cortex appears structurally intact with no atrophic changes - no signs of atrophy detected in the parietal lobe - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. occipital gyrus (mild atrophy on the right) and calcarine cortex (normal-to-mild atrophy on the right) - temporal lobe maintains its normal morphology without atrophic features - insular cortex remains normal, with no signs of tissue loss - frontal lobe maintains its normal morphology without atrophic features For the subcortical structures: - no signs of atrophy detected in the amygdala - normal-to-mild bilateral pallidum atrophy - ventral dc appears structurally intact with no atrophic changes - thalamus maintains its normal morphology without atrophic features - hippocampus appears structurally intact with no atrophic changes - caudate atrophy (normal-to-mild on the left, normal on the right) - basal forebrain remains normal, with no signs of tissue loss - normal-to-mild bilateral putamen atrophy - accumbens atrophy (normal on the left, normal-to-mild on the right)
CN
ADNI_032_S_4386_MR_MPRAGE_br_raw_20111216100730796_153_S133449_I272396
On a T1-weighted brain MRI we observed: For the cerebral cortex: - no signs of atrophy detected in the insular cortex - limbic cortex remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the temporal lobe - no observable atrophic alterations in the occipital lobe - frontal lobe maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the parietal lobe For the subcortical structures: - no observable atrophic alterations in the putamen - pallidum appears structurally intact with no atrophic changes - no signs of atrophy detected in the accumbens - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - no signs of atrophy detected in the thalamus - ventral dc maintains its normal morphology without atrophic features - caudate remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the amygdala - hippocampus presents with a healthy appearance, free from atrophy For the ventricles: - the external csf shows no structural abnormalities indicative of enlargement - lateral ventricle is free from enlargement or excessive growth - no pathological changes consistent with enlargement noted in the 4th ventricle - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - no enlargement observed in the 3rd ventricle
CN
ADNI_031_S_4496_MR_MPRAGE_br_raw_20120203142353809_150_S139647_I282638
On a T1-weighted brain MRI we observed: For the ventricles: - inf. lateral ventricle is free from enlargement or excessive growth - no observable enlargement or abnormal growth in the 3rd ventricle - normal-to-mild enlargement of the external csf - 4th ventricle remains within normal size parameters, with no enlargement detected - no observable enlargement or abnormal growth in the lateral ventricle For the subcortical structures: - basal forebrain maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the amygdala - pallidum atrophy (normal-to-mild on the left, normal on the right) - putamen atrophy (normal-to-mild on the left, normal on the right) - ventral dc atrophy (normal on the left, normal-to-mild on the right) - hippocampus remains normal, with no signs of tissue loss - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral caudate atrophy - thalamus maintains its normal morphology without atrophic features For the cerebral cortex: - no observable atrophic alterations in the limbic cortex - no pathological changes consistent with atrophy detected in the frontal lobe - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the right) - no evidence of atrophy or degeneration in the insular cortex - normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: lingual gyrus (normal-to-mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy on the right), middle occipital gyrus (normal-to-mild atrophy both left/right) and occipital pole (normal-to-mild atrophy on the right) - temporal lobe remains normal, with no signs of tissue loss
CN
NIFD_1_S_0312_MR_t1_mprage_S3_DIS3D_br_raw_20160909141655212_27_S498027_I774594
On a T1-weighted brain MRI we observed: For the ventricles: - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - no enlargement observed in the 4th ventricle - no observable enlargement or abnormal growth in the 3rd ventricle - normal-to-mild enlargement of the external csf - no observable enlargement or abnormal growth in the lateral ventricle For the subcortical structures: - pallidum presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the putamen - no signs of atrophy detected in the amygdala - thalamus remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the ventral dc - accumbens atrophy (normal on the left, normal-to-mild on the right) - no evidence of atrophy or degeneration in the caudate - basal forebrain presents with a healthy appearance, free from atrophy - the hippocampus shows no structural abnormalities indicative of atrophy For the cerebral cortex: - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: orbital inf. frontal gyrus (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right), supplementary motor cortex (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: inf. occipital gyrus (normal-to-mild atrophy on the right) and occipital fusiform gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the limbic cortex, with focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the right), temporal pole (normal-to-mild atrophy both left/right) and transverse temporal gyrus (normal-to-mild atrophy on the right) - insular cortex presents with a healthy appearance, free from atrophy - parietal lobe maintains its normal morphology without atrophic features
CN
ADNI_082_S_5184_MR_MPRAGE_br_raw_20130523103301800_81_S190368_I373616
On a T1-weighted brain MRI we observed: For the subcortical structures: - normal-to-mild bilateral amygdala atrophy - basal forebrain maintains its normal morphology without atrophic features - ventral dc presents with a healthy appearance, free from atrophy - hippocampus atrophy (mild on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the accumbens - pallidum maintains its normal morphology without atrophic features - the putamen shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the caudate - thalamus remains normal, with no signs of tissue loss For the cerebral cortex: - no pathological changes consistent with atrophy detected in the occipital lobe - no degenerative or atrophic changes noted in the limbic cortex - insular cortex maintains its normal morphology without atrophic features - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: sup. frontal gyrus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (mild atrophy on the left) and orbital inf. frontal gyrus (normal-to-mild atrophy on the left) - parietal lobe atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), postcentral gyrus (normal-to-mild atrophy on the right), postcentral gyrus medial segment (normal-to-mild atrophy on the left), precuneus (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the left) - temporal lobe atrophy (mild-to-moderate on the left, normal on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy on the left), temporal pole (normal-to-mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the left) For the ventricles: - 4th ventricle maintains its normal volume without signs of enlargement - no signs of enlargement detected in the lateral ventricle - no pathological changes consistent with enlargement noted in the 3rd ventricle - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - normal-to-mild enlargement of the external csf
AD
ADNI_023_S_4501_MR_MPRAGE_br_raw_20120322171932070_91_S144533_I291858
On a T1-weighted brain MRI we observed: For the subcortical structures: - no observable atrophic alterations in the pallidum - accumbens atrophy (normal on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the ventral dc - amygdala atrophy (normal-to-mild on the left, severe on the right) - caudate appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the thalamus - hippocampus atrophy (normal-to-mild on the left, severe on the right) - no degenerative or atrophic changes noted in the basal forebrain - putamen remains normal, with no signs of tissue loss For the cerebral cortex: - insular cortex maintains its normal morphology without atrophic features - frontal lobe maintains its normal morphology without atrophic features - temporal lobe atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the right), temporal pole (mild-to-moderate atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the left) - occipital lobe maintains its normal morphology without atrophic features - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: postcentral gyrus medial segment (normal-to-mild atrophy on the right) and sup. parietal lobule (normal-to-mild atrophy on the right) - the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and entorhinal area (normal-to-mild atrophy on the right) For the ventricles: - no enlargement observed in the lateral ventricle - inf. lateral ventricle enlargement (normal on the left, mild-to-moderate on the right) - no signs of enlargement detected in the external csf - 3rd ventricle is free from enlargement or excessive growth - 4th ventricle maintains its normal volume without signs of enlargement
AD
ADNI_116_S_4338_MR_MPRAGE_br_raw_20111107090101281_142_S128214_I264968
On a T1-weighted brain MRI we observed: For the subcortical structures: - ventral dc atrophy (normal on the left, normal-to-mild on the right) - no observable atrophic alterations in the basal forebrain - normal-to-mild bilateral hippocampus atrophy - amygdala atrophy (moderate on the left, mild on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral accumbens atrophy - normal-to-mild bilateral pallidum atrophy - normal-to-mild bilateral putamen atrophy - no degenerative or atrophic changes noted in the caudate For the ventricles: - no signs of enlargement detected in the lateral ventricle - 4th ventricle appears structurally intact, with no evidence of enlargement - no enlargement observed in the external csf - normal-to-mild enlargement of the 3rd ventricle - moderate-to-severe bilateral inf. lateral ventricle enlargement For the cerebral cortex: - limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy both left/right) - no pathological changes consistent with atrophy detected in the frontal lobe - occipital lobe remains normal, with no signs of tissue loss - parietal lobe maintains its normal morphology without atrophic features - temporal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the right), planum polare (normal-to-mild atrophy both left/right), inf. temporal gyrus (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the right) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and moderate atrophy on the right) and posterior insula (normal-to-mild atrophy both left/right)
AD
ADNI_128_S_4772_MR_MPRAGE_br_raw_20120614115153399_134_S154042_I310620
On a T1-weighted brain MRI we observed: For the subcortical structures: - caudate maintains its normal morphology without atrophic features - amygdala atrophy (normal-to-mild on the left, normal on the right) - no evidence of atrophy or degeneration in the putamen - no signs of atrophy detected in the ventral dc - pallidum appears structurally intact with no atrophic changes - accumbens atrophy (normal on the left, normal-to-mild on the right) - no signs of atrophy detected in the thalamus - no degenerative or atrophic changes noted in the hippocampus - no pathological changes consistent with atrophy detected in the basal forebrain For the cerebral cortex: - temporal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the right) and temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) - no signs of atrophy detected in the occipital lobe - no evidence of atrophy or degeneration in the limbic cortex - insular cortex maintains its normal morphology without atrophic features - parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy on the right) and supramarginal gyrus (normal-to-mild atrophy on the right) For the ventricles: - no abnormal enlargement observed in the 4th ventricle - external csf remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the 3rd ventricle - inf. lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
AD
ADNI_094_S_4459_MR_Accelerated_SAG_IR-SPGR__br_raw_20120222110144176_106_S140152_I283439
On a T1-weighted brain MRI we observed: For the ventricles: - no observable enlargement or abnormal growth in the 3rd ventricle - no abnormal enlargement observed in the inf. lateral ventricle - the 4th ventricle shows no structural abnormalities indicative of enlargement - no enlargement observed in the lateral ventricle - no pathological changes consistent with enlargement noted in the external csf For the subcortical structures: - thalamus maintains its normal morphology without atrophic features - normal-to-mild bilateral pallidum atrophy - no observable atrophic alterations in the amygdala - basal forebrain presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the ventral dc - caudate atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral putamen atrophy - accumbens atrophy (normal on the left, normal-to-mild on the right) - hippocampus presents with a healthy appearance, free from atrophy For the cerebral cortex: - temporal lobe appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the limbic cortex - insular cortex maintains its normal morphology without atrophic features - parietal lobe appears structurally intact with no atrophic changes - frontal lobe remains normal, with no signs of tissue loss - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. occipital gyrus (mild atrophy on the right) and calcarine cortex (normal-to-mild atrophy on the right)
CN
NIFD_1_S_0001_MR_t1_mprage_S3_DIS3D_br_raw_20110414093817218_156_S104261_I227685
On a T1-weighted brain MRI we observed: For the ventricles: - 4th ventricle appears structurally intact, with no evidence of enlargement - 3rd ventricle is free from enlargement or excessive growth - lateral ventricle is free from enlargement or excessive growth - inf. lateral ventricle maintains its normal volume without signs of enlargement - the external csf shows no structural abnormalities indicative of enlargement For the cerebral cortex: - parietal lobe presents with a healthy appearance, free from atrophy - temporal lobe remains normal, with no signs of tissue loss - insular cortex appears structurally intact with no atrophic changes - no observable atrophic alterations in the frontal lobe - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy on the left) - no pathological changes consistent with atrophy detected in the occipital lobe For the subcortical structures: - caudate presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the pallidum - accumbens presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the amygdala - putamen remains normal, with no signs of tissue loss - basal forebrain atrophy (normal on the left, normal-to-mild on the right) - no pathological changes consistent with atrophy detected in the hippocampus - thalamus appears structurally intact with no atrophic changes - no signs of atrophy detected in the ventral dc
CN
ADNI_116_S_4537_MR_MPRAGE_br_raw_20120217123755224_132_S141133_I285465
On a T1-weighted brain MRI we observed: For the subcortical structures: - putamen atrophy (normal-to-mild on the left, normal on the right) - no evidence of atrophy or degeneration in the pallidum - amygdala atrophy (mild on the left, normal-to-mild on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - ventral dc maintains its normal morphology without atrophic features - hippocampus appears structurally intact with no atrophic changes - caudate atrophy (mild on the left, normal-to-mild on the right) - accumbens atrophy (mild on the left, normal-to-mild on the right) - basal forebrain presents with a healthy appearance, free from atrophy For the ventricles: - no pathological changes consistent with enlargement noted in the inf. lateral ventricle - mild enlargement of the external csf - no observable enlargement or abnormal growth in the 4th ventricle - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - no abnormal enlargement observed in the 3rd ventricle For the cerebral cortex: - temporal lobe atrophy (moderate-to-severe on the left, mild on the right), with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy on the left), inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the left), temporal pole (normal-to-mild atrophy on the right) and fusiform gyrus (normal-to-mild atrophy on the left) - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: cuneus (normal-to-mild atrophy on the left), lingual gyrus (normal-to-mild atrophy on the right) and middle occipital gyrus (normal-to-mild atrophy on the right) - no evidence of atrophy or degeneration in the limbic cortex - the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (mild atrophy on the left) - insular cortex atrophy (mild-to-moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy both left/right) - frontal lobe atrophy (mild-to-moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left), middle frontal gyrus (mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the left) and lateral orbital gyrus (normal-to-mild atrophy on the left)
AD