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ALLFTD-wCN-2sigma-higherRecall-wCS-testset-T3RepXMRI-DNT

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subject string	txt_report string	gold_diagnosis string	cognitive_txt string
FTLD_203413336_03631_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10451002	On a T1-weighted brain MRI of a 72-year-old female subject, we observed: For the cerebral cortex: - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (mild atrophy on the left and severe atrophy on the right), medial frontal cortex (mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right) and precentral gyrus (normal-to-mild atrophy on the right) - parietal lobe appears structurally intact with no atrophic changes - temporal lobe atrophy (severe on the left, normal on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left), planum polare (mild-to-moderate atrophy on the left), planum temporale (normal-to-mild atrophy on the right), middle temporal gyrus (mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and temporal pole (severe atrophy on the left and normal-to-mild atrophy on the right) - insular cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left), posterior insula (normal-to-mild atrophy on the left) and central operculum (normal-to-mild atrophy on the left) - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left) and entorhinal area (normal-to-mild atrophy on the left) - no signs of atrophy detected in the occipital lobe For the subcortical structures: - hippocampus atrophy (normal-to-mild on the left, normal on the right) - ventral dc presents with a healthy appearance, free from atrophy - basal forebrain appears structurally intact with no atrophic changes - no signs of atrophy detected in the pallidum - caudate appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the putamen - thalamus remains normal, with no signs of tissue loss - amygdala atrophy (severe on the left, mild on the right) - accumbens atrophy (mild-to-moderate on the left, normal-to-mild on the right) For the ventricles: - lateral ventricle is free from enlargement or excessive growth - normal-to-mild enlargement of the external csf - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - 3rd ventricle remains within normal size parameters, with no enlargement detected - 4th ventricle maintains its normal volume without signs of enlargement	SD	We have the following subject's personal information: - The subject is a female of 72.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 12. - On the semantic categorical fluency test, the subject named 7 animals in 60 seconds. She named 6 vegetables in 60 seconds. - On the Number Span forward test, her longest span forward was 4. On the Number Span backward test, her longest span backward was 3. - On the Trail Making Test Part A, her total number of seconds to complete is 18, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 87, her number of commission errors is 0, her number of correct lines is 24. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203948568_01864_MR_Sagittal_MP-Rage_br_raw_20230209093332949_I10183206	On a T1-weighted brain MRI of a 59-year-old male subject, we observed: For the subcortical structures: - putamen atrophy (mild-to-moderate on the left, normal-to-mild on the right) - basal forebrain appears structurally intact with no atrophic changes - pallidum atrophy (normal-to-mild on the left, normal on the right) - the ventral dc shows no structural abnormalities indicative of atrophy - severe bilateral accumbens atrophy - caudate atrophy (severe on the left, mild on the right) - thalamus remains normal, with no signs of tissue loss - severe bilateral amygdala atrophy - hippocampus atrophy (moderate-to-severe on the left, mild-to-moderate on the right) For the ventricles: - no enlargement observed in the 4th ventricle - inf. lateral ventricle enlargement (severe on the left, normal-to-mild on the right) - normal-to-mild enlargement of the external csf - lateral ventricle is free from enlargement or excessive growth - no observable enlargement or abnormal growth in the 3rd ventricle For the cerebral cortex: - the parietal lobe shows no structural abnormalities indicative of atrophy - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate atrophy on the right), posterior insula (normal-to-mild atrophy on the left) and frontal operculum (normal-to-mild atrophy on the left) - frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left) and sup. frontal gyrus (normal-to-mild atrophy on the left) - mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), posterior cingulate gyrus (normal-to-mild atrophy on the right) and parahippocampal gyrus (moderate atrophy on the left and mild atrophy on the right) - no observable atrophic alterations in the occipital lobe - temporal lobe atrophy (moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy both left/right), middle temporal gyrus (mild atrophy both left/right) and temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right)	bvFTD	We have the following subject's personal information: - The subject is a male of 59.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 28. - On the semantic categorical fluency test, the subject named 14 animals in 60 seconds. He named 6 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 12. - On the Number Span forward test, his longest span forward was 8. On the Number Span backward test, his longest span backward was 6. - On the Trail Making Test Part A, his total number of seconds to complete is 34, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 45, his number of commission errors is 0, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in elation or euphoria, nighttime behaviors, a moderate (significant, but not dramatic) change in delusions, agitation or aggression, anxiety, a mild (noticeable, but not significant) change in depression or dysphoria, disinhibition, irritability or lability, appetite and eating. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203955366_03665_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451040	On a T1-weighted brain MRI of a 24-year-old female subject, we observed: For the subcortical structures: - basal forebrain atrophy (normal on the left, normal-to-mild on the right) - accumbens maintains its normal morphology without atrophic features - normal-to-mild bilateral ventral dc atrophy - normal-to-mild bilateral putamen atrophy - amygdala appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the hippocampus - normal-to-mild bilateral pallidum atrophy - no observable atrophic alterations in the thalamus - no evidence of atrophy or degeneration in the caudate For the ventricles: - 4th ventricle maintains its normal volume without signs of enlargement - no signs of enlargement detected in the external csf - lateral ventricle enlargement (normal-to-mild on the left, normal on the right) - normal-to-mild enlargement of the 3rd ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement For the cerebral cortex: - no observable atrophic alterations in the frontal lobe - limbic cortex remains normal, with no signs of tissue loss - no observable atrophic alterations in the insular cortex - temporal lobe appears structurally intact with no atrophic changes - parietal lobe maintains its normal morphology without atrophic features - occipital lobe appears structurally intact with no atrophic changes	CN	We have the following subject's personal information: - The subject is a female of 24.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 25. - On the semantic categorical fluency test, the subject named 10 animals in 60 seconds. She named 12 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 27. - On the Number Span forward test, her longest span forward was 8. On the Number Span backward test, her longest span backward was 4. - On the Trail Making Test Part A, her total number of seconds to complete is 43, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 70, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203137272_01273_MR_Sagittal_MP-Rage_br_raw_20230206162542918_I10181633	On a T1-weighted brain MRI of a 24-year-old female subject, we observed: For the cerebral cortex: - no degenerative or atrophic changes noted in the temporal lobe - limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the right) and posterior cingulate gyrus (normal-to-mild atrophy on the right) - occipital lobe maintains its normal morphology without atrophic features - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: lateral orbital gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the left) and gyrus rectus (normal-to-mild atrophy on the left) - no pathological changes consistent with atrophy detected in the insular cortex - the parietal lobe shows no structural abnormalities indicative of atrophy For the subcortical structures: - hippocampus atrophy (normal on the left, normal-to-mild on the right) - accumbens presents with a healthy appearance, free from atrophy - basal forebrain maintains its normal morphology without atrophic features - caudate presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the pallidum - no degenerative or atrophic changes noted in the amygdala - thalamus atrophy (normal on the left, normal-to-mild on the right) - no degenerative or atrophic changes noted in the putamen - ventral dc remains normal, with no signs of tissue loss For the ventricles: - no abnormal enlargement observed in the 4th ventricle - no abnormal enlargement observed in the 3rd ventricle - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - lateral ventricle enlargement (mild on the left, severe on the right) - external csf remains within normal size parameters, with no enlargement detected	CN	We have the following subject's personal information: - The subject is a female of 24.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) - The subject is left-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 29. - On the semantic categorical fluency test, the subject named 24 animals in 60 seconds. She named 14 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 25. - On the Number Span forward test, her longest span forward was 9. On the Number Span backward test, her longest span backward was 7. - On the Trail Making Test Part A, her total number of seconds to complete is 27, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 42, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203412030_01031_MR_Sagittal_MP-Rage_br_raw_20230206164632938_I10181769	On a T1-weighted brain MRI of a 64-year-old male subject, we observed: For the ventricles: - normal-to-mild enlargement of the external csf - no abnormal enlargement observed in the inf. lateral ventricle - lateral ventricle is free from enlargement or excessive growth - 3rd ventricle is free from enlargement or excessive growth - no signs of enlargement detected in the 4th ventricle For the subcortical structures: - putamen atrophy (normal on the left, normal-to-mild on the right) - no evidence of atrophy or degeneration in the basal forebrain - no pathological changes consistent with atrophy detected in the hippocampus - no observable atrophic alterations in the accumbens - no signs of atrophy detected in the ventral dc - thalamus appears structurally intact with no atrophic changes - normal-to-mild bilateral caudate atrophy - amygdala remains normal, with no signs of tissue loss - no observable atrophic alterations in the pallidum For the cerebral cortex: - no observable atrophic alterations in the occipital lobe - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the right), sup. parietal lobule (normal-to-mild atrophy both left/right) and postcentral gyrus (normal-to-mild atrophy on the left) - frontal lobe presents with a healthy appearance, free from atrophy - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) - limbic cortex presents with a healthy appearance, free from atrophy - mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the right), planum temporale (mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left) and temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right)	CN	We have the following subject's personal information: - The subject is a male of 64.0 years old. - He has 17.0 years of education - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 25 animals in 60 seconds. He named 17 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 39. - On the Number Span forward test, his longest span forward was 6. On the Number Span backward test, his longest span backward was 5. - On the Trail Making Test Part A, his total number of seconds to complete is 25, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 88, his number of commission errors is 1, his number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203859805_01505_MR_Sagittal_MP-Rage_br_raw_20230206172921852_I10182096	On a T1-weighted brain MRI of a 28-year-old male subject, we observed: For the ventricles: - normal-to-mild enlargement of the external csf - normal-to-mild enlargement of the 3rd ventricle - no pathological changes consistent with enlargement noted in the 4th ventricle - lateral ventricle is free from enlargement or excessive growth - no pathological changes consistent with enlargement noted in the inf. lateral ventricle For the cerebral cortex: - no observable atrophic alterations in the frontal lobe - temporal lobe maintains its normal morphology without atrophic features - limbic cortex maintains its normal morphology without atrophic features - no signs of atrophy detected in the occipital lobe - no degenerative or atrophic changes noted in the insular cortex - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right) and postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) For the subcortical structures: - no evidence of atrophy or degeneration in the caudate - pallidum presents with a healthy appearance, free from atrophy - ventral dc atrophy (normal-to-mild on the left, mild-to-moderate on the right) - thalamus atrophy (moderate-to-severe on the left, mild on the right) - no evidence of atrophy or degeneration in the amygdala - normal-to-mild bilateral putamen atrophy - no pathological changes consistent with atrophy detected in the hippocampus - accumbens atrophy (normal on the left, normal-to-mild on the right) - no observable atrophic alterations in the basal forebrain	CN	We have the following subject's personal information: - The subject is a male of 28.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 28. - On the semantic categorical fluency test, the subject named 12 animals in 60 seconds. He named 13 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 7. - On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 3. - On the Trail Making Test Part A, his total number of seconds to complete is 32, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 123, his number of commission errors is 1, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in depression or dysphoria. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203424200_01002_MR_Sagittal_MP-Rage_br_raw_20230206132639815_I10181006	On a T1-weighted brain MRI of a 54-year-old female subject, we observed: For the cerebral cortex: - no degenerative or atrophic changes noted in the frontal lobe - temporal lobe presents with a healthy appearance, free from atrophy - occipital lobe maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the limbic cortex - insular cortex maintains its normal morphology without atrophic features - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left) and postcentral gyrus (normal-to-mild atrophy on the right) For the subcortical structures: - thalamus maintains its normal morphology without atrophic features - putamen presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the accumbens - no pathological changes consistent with atrophy detected in the amygdala - no observable atrophic alterations in the ventral dc - pallidum presents with a healthy appearance, free from atrophy - the basal forebrain shows no structural abnormalities indicative of atrophy - hippocampus maintains its normal morphology without atrophic features - caudate appears structurally intact with no atrophic changes For the ventricles: - 3rd ventricle remains within normal size parameters, with no enlargement detected - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - 4th ventricle remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the external csf - lateral ventricle remains within normal size parameters, with no enlargement detected	CN	We have the following subject's personal information: - The subject is a female of 54.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 27 animals in 60 seconds. She named 21 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 26. - On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 18, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 55, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203208248_01840_MR_Sagittal_MP-Rage_br_raw_20230124205743547_I10178463	On a T1-weighted brain MRI of a 47-year-old male subject, we observed: For the cerebral cortex: - temporal lobe maintains its normal morphology without atrophic features - occipital lobe maintains its normal morphology without atrophic features - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: frontal operculum (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy on the right) - limbic cortex presents with a healthy appearance, free from atrophy - frontal lobe appears structurally intact with no atrophic changes - parietal lobe maintains its normal morphology without atrophic features For the ventricles: - no signs of enlargement detected in the inf. lateral ventricle - no signs of enlargement detected in the 4th ventricle - no abnormal enlargement observed in the lateral ventricle - normal-to-mild enlargement of the 3rd ventricle - external csf remains within normal size parameters, with no enlargement detected For the subcortical structures: - hippocampus appears structurally intact with no atrophic changes - no signs of atrophy detected in the ventral dc - no pathological changes consistent with atrophy detected in the basal forebrain - accumbens presents with a healthy appearance, free from atrophy - pallidum appears structurally intact with no atrophic changes - amygdala presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the thalamus - no pathological changes consistent with atrophy detected in the putamen - caudate maintains its normal morphology without atrophic features	CN	We have the following subject's personal information: - The subject is a male of 47.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) - The subject is left-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 24 animals in 60 seconds. He named 13 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 32. - On the Number Span forward test, his longest span forward was 9. On the Number Span backward test, his longest span backward was 7. - On the Trail Making Test Part A, his total number of seconds to complete is 22, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 44, his number of commission errors is 0, his number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203424662_01262_MR_Sagittal_MP-Rage_br_raw_20230206140046807_I10181116	On a T1-weighted brain MRI of a 54-year-old male subject, we observed: For the cerebral cortex: - occipital lobe maintains its normal morphology without atrophic features - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy on the left) - no evidence of atrophy or degeneration in the frontal lobe - insular cortex maintains its normal morphology without atrophic features - no observable atrophic alterations in the limbic cortex - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy both left/right) and temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) For the ventricles: - lateral ventricle appears structurally intact, with no evidence of enlargement - 3rd ventricle maintains its normal volume without signs of enlargement - no enlargement observed in the 4th ventricle - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - no enlargement observed in the external csf For the subcortical structures: - no pathological changes consistent with atrophy detected in the ventral dc - no signs of atrophy detected in the pallidum - no signs of atrophy detected in the basal forebrain - no degenerative or atrophic changes noted in the putamen - no evidence of atrophy or degeneration in the caudate - amygdala presents with a healthy appearance, free from atrophy - thalamus presents with a healthy appearance, free from atrophy - normal-to-mild bilateral accumbens atrophy - hippocampus atrophy (normal-to-mild on the left, normal on the right)	CN	We have the following subject's personal information: - The subject is a male of 54.0 years old. - He has 14.0 years of education - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 30. - On the semantic categorical fluency test, the subject named 9 animals in 60 seconds. He named 13 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 25. - On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 3. - On the Trail Making Test Part A, his total number of seconds to complete is 28, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 70, his number of commission errors is 0, his number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203214809_02901_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10178019	On a T1-weighted brain MRI of a 32-year-old male subject, we observed: For the subcortical structures: - caudate presents with a healthy appearance, free from atrophy - pallidum appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the ventral dc - thalamus appears structurally intact with no atrophic changes - accumbens appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the basal forebrain - no signs of atrophy detected in the amygdala - no degenerative or atrophic changes noted in the hippocampus - putamen maintains its normal morphology without atrophic features For the cerebral cortex: - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in transverse temporal gyrus (severe atrophy on the left) - no observable atrophic alterations in the insular cortex - limbic cortex maintains its normal morphology without atrophic features - parietal lobe maintains its normal morphology without atrophic features - no observable atrophic alterations in the frontal lobe - the occipital lobe shows no structural abnormalities indicative of atrophy For the ventricles: - no observable enlargement or abnormal growth in the external csf - no pathological changes consistent with enlargement noted in the lateral ventricle - 3rd ventricle is free from enlargement or excessive growth - no abnormal enlargement observed in the inf. lateral ventricle - no enlargement observed in the 4th ventricle	CN	We have the following subject's personal information: - The subject is a male of 32.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 26 animals in 60 seconds. He named 21 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 18. - On the Number Span forward test, his longest span forward was 8. On the Number Span backward test, his longest span backward was 5. - On the Trail Making Test Part A, his total number of seconds to complete is 30, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 54, his number of commission errors is 0, his number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203788637_02738_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176931	On a T1-weighted brain MRI of a 73-year-old male subject, we observed: For the cerebral cortex: - no evidence of atrophy or degeneration in the frontal lobe - limbic cortex atrophy (mild-to-moderate on the left, mild on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and moderate atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the left) - the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the right) - occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: cuneus (normal-to-mild atrophy on the left), lingual gyrus (mild atrophy on the left), occipital fusiform gyrus (normal-to-mild atrophy on the right) and inf. occipital gyrus (normal-to-mild atrophy on the left) - no observable atrophic alterations in the parietal lobe - severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and severe atrophy on the right), temporal pole (severe atrophy both left/right), planum temporale (normal-to-mild atrophy on the right), planum polare (mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right) For the subcortical structures: - ventral dc maintains its normal morphology without atrophic features - severe bilateral amygdala atrophy - putamen atrophy (normal-to-mild on the left, moderate-to-severe on the right) - accumbens atrophy (mild on the left, moderate-to-severe on the right) - no degenerative or atrophic changes noted in the basal forebrain - the thalamus shows no structural abnormalities indicative of atrophy - pallidum atrophy (normal on the left, normal-to-mild on the right) - hippocampus atrophy (mild on the left, moderate on the right) - caudate atrophy (normal-to-mild on the left, mild on the right) For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - no observable enlargement or abnormal growth in the 4th ventricle - lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - mild enlargement of the external csf - severe bilateral inf. lateral ventricle enlargement	bvFTD	We have the following subject's personal information: - The subject is a male of 73.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 2. - On the semantic categorical fluency test, the subject named 5 animals in 60 seconds. He named 0 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 0. - On the Number Span forward test, his longest span forward was 6. On the Number Span backward test, his longest span backward was 0. - On the Trail Making Test Part A, his total number of seconds to complete is 86, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 205, his number of commission errors is 0, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in disinhibition, irritability or lability, nighttime behaviors, a moderate (significant, but not dramatic) change in agitation or aggression, elation or euphoria, a mild (noticeable, but not significant) change in anxiety. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203129855_03552_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450920	On a T1-weighted brain MRI of a 76-year-old male subject, we observed: For the subcortical structures: - mild bilateral accumbens atrophy - ventral dc atrophy (moderate-to-severe on the left, normal-to-mild on the right) - putamen atrophy (moderate on the left, normal-to-mild on the right) - basal forebrain appears structurally intact with no atrophic changes - severe bilateral amygdala atrophy - caudate atrophy (mild-to-moderate on the left, normal-to-mild on the right) - thalamus atrophy (mild on the left, normal on the right) - pallidum atrophy (mild on the left, normal on the right) - hippocampus atrophy (severe on the left, mild on the right) For the cerebral cortex: - temporal lobe atrophy (severe on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left), temporal pole (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the right) - frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (mild atrophy both left/right), posterior orbital gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy both left/right), supplementary motor cortex (normal-to-mild atrophy on the right) and opercular inf. frontal gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (mild-to-moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the left), middle cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right) - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lingual gyrus (mild atrophy on the right) and sup. occipital gyrus (normal-to-mild atrophy on the right) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), posterior insula (normal-to-mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the left) - no evidence of atrophy or degeneration in the parietal lobe For the ventricles: - no signs of enlargement detected in the lateral ventricle - the 4th ventricle shows no structural abnormalities indicative of enlargement - moderate-to-severe enlargement of the external csf - no observable enlargement or abnormal growth in the 3rd ventricle - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right)	SD	We have the following subject's personal information: - The subject is a male of 76.0 years old. - He has 20.0 years of education (equivalent to doctorate) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 7. - On the semantic categorical fluency test, the subject named 0 animals in 60 seconds. He named 0 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 2. - On the Number Span forward test, his longest span forward was 4. On the Number Span backward test, his longest span backward was 3. - On the Trail Making Test Part A, his total number of seconds to complete is 47, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 153, his number of commission errors is 0, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in apathy or indifference. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203888981_02188_MR_Sagittal_MP-Rage_br_raw_20230206184523694_I10182636	On a T1-weighted brain MRI of a 76-year-old male subject, we observed: For the subcortical structures: - the thalamus shows no structural abnormalities indicative of atrophy - putamen atrophy (moderate on the left, mild-to-moderate on the right) - normal-to-mild bilateral pallidum atrophy - no evidence of atrophy or degeneration in the ventral dc - normal-to-mild bilateral accumbens atrophy - amygdala remains normal, with no signs of tissue loss - normal-to-mild bilateral caudate atrophy - hippocampus atrophy (normal-to-mild on the left, mild on the right) - no signs of atrophy detected in the basal forebrain For the ventricles: - normal-to-mild bilateral lateral ventricle enlargement - 4th ventricle maintains its normal volume without signs of enlargement - inf. lateral ventricle enlargement (mild on the left, severe on the right) - no pathological changes consistent with enlargement noted in the external csf - 3rd ventricle maintains its normal volume without signs of enlargement For the cerebral cortex: - parietal lobe presents with a healthy appearance, free from atrophy - the frontal lobe shows no structural abnormalities indicative of atrophy - temporal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the left), temporal pole (normal-to-mild atrophy on the right) and transverse temporal gyrus (normal-to-mild atrophy on the left) - occipital lobe remains normal, with no signs of tissue loss - limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left), parahippocampal gyrus (normal-to-mild atrophy both left/right) and posterior cingulate gyrus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the insular cortex	bvFTD	We have the following subject's personal information: - The subject is a male of 76.0 years old. - He has 20.0 years of education (equivalent to doctorate) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 23. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 6. - On the Number Span forward test, his longest span forward was 3. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in delusions, agitation or aggression, apathy or indifference, irritability or lability, motor disturbance, nighttime behaviors, appetite and eating, a moderate (significant, but not dramatic) change in anxiety, disinhibition. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. His standard CDR sum of boxes is 12.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203146797_01794_MR_Sagittal_MP-Rage_br_raw_20230124205359108_I10178431	On a T1-weighted brain MRI of a 48-year-old female subject, we observed: For the cerebral cortex: - frontal lobe remains normal, with no signs of tissue loss - the temporal lobe shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the parietal lobe - occipital lobe appears structurally intact with no atrophic changes - no observable atrophic alterations in the limbic cortex - the insular cortex shows no structural abnormalities indicative of atrophy For the subcortical structures: - normal-to-mild bilateral ventral dc atrophy - normal-to-mild bilateral amygdala atrophy - thalamus atrophy (normal-to-mild on the left, normal on the right) - no signs of atrophy detected in the caudate - hippocampus appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the accumbens - no evidence of atrophy or degeneration in the putamen - basal forebrain atrophy (normal on the left, normal-to-mild on the right) - no observable atrophic alterations in the pallidum For the ventricles: - 3rd ventricle is free from enlargement or excessive growth - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - normal-to-mild enlargement of the external csf - no enlargement observed in the lateral ventricle - 4th ventricle appears structurally intact, with no evidence of enlargement	CN	We have the following subject's personal information: - The subject is a female of 48.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 30. - On the semantic categorical fluency test, the subject named 32 animals in 60 seconds. She named 18 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 16. - On the Number Span forward test, her longest span forward was 9. On the Number Span backward test, her longest span backward was 8. - On the Trail Making Test Part A, her total number of seconds to complete is 21, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 36, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203743678_02874_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177050	On a T1-weighted brain MRI of a 37-year-old female subject, we observed: For the cerebral cortex: - occipital lobe presents with a healthy appearance, free from atrophy - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left), middle cingulate gyrus (normal-to-mild atrophy on the left) and posterior cingulate gyrus (normal-to-mild atrophy on the left) - insular cortex maintains its normal morphology without atrophic features - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right) and lateral orbital gyrus (normal-to-mild atrophy on the right) - parietal lobe presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the temporal lobe For the ventricles: - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - no observable enlargement or abnormal growth in the 4th ventricle - no signs of enlargement detected in the 3rd ventricle - no observable enlargement or abnormal growth in the external csf - lateral ventricle is free from enlargement or excessive growth For the subcortical structures: - no degenerative or atrophic changes noted in the putamen - pallidum remains normal, with no signs of tissue loss - the accumbens shows no structural abnormalities indicative of atrophy - caudate remains normal, with no signs of tissue loss - no observable atrophic alterations in the amygdala - no observable atrophic alterations in the thalamus - the basal forebrain shows no structural abnormalities indicative of atrophy - hippocampus appears structurally intact with no atrophic changes - ventral dc presents with a healthy appearance, free from atrophy	CN	We have the following subject's personal information: - The subject is a female of 37.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 23 animals in 60 seconds. She named 12 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 24. - On the Number Span forward test, her longest span forward was 9. On the Number Span backward test, her longest span backward was 6. - On the Trail Making Test Part A, her total number of seconds to complete is 21, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 29, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203809961_03160_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178326	On a T1-weighted brain MRI of a 49-year-old male subject, we observed: For the cerebral cortex: - limbic cortex atrophy (moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (mild atrophy on the left), posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left) - severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and moderate-to-severe atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy both left/right) and supplementary motor cortex (normal-to-mild atrophy on the right) - parietal lobe atrophy (mild-to-moderate on the left, mild on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the right), postcentral gyrus (mild atrophy both left/right), precuneus (normal-to-mild atrophy on the left), supramarginal gyrus (normal-to-mild atrophy on the left) and sup. parietal lobule (normal-to-mild atrophy on the left) - severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and moderate atrophy on the right), posterior insula (mild atrophy both left/right), central operculum (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), frontal operculum (normal-to-mild atrophy both left/right) and parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) - temporal lobe atrophy (moderate-to-severe on the left, mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy both left/right), middle temporal gyrus (mild atrophy on the left), transverse temporal gyrus (mild atrophy both left/right) and temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right) - occipital lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), cuneus (normal-to-mild atrophy on the right), inf. occipital gyrus (normal-to-mild atrophy on the right), middle occipital gyrus (normal-to-mild atrophy on the right) and sup. occipital gyrus (normal-to-mild atrophy on the right) For the ventricles: - severe enlargement of the 3rd ventricle - normal-to-mild enlargement of the external csf - no signs of enlargement detected in the 4th ventricle - severe bilateral lateral ventricle enlargement - severe bilateral inf. lateral ventricle enlargement For the subcortical structures: - severe bilateral caudate atrophy - hippocampus atrophy (normal-to-mild on the left, mild-to-moderate on the right) - severe bilateral accumbens atrophy - no degenerative or atrophic changes noted in the thalamus - basal forebrain appears structurally intact with no atrophic changes - ventral dc presents with a healthy appearance, free from atrophy - severe bilateral putamen atrophy - moderate-to-severe bilateral amygdala atrophy - no observable atrophic alterations in the pallidum	bvFTD	We have the following subject's personal information: - The subject is a male of 49.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 17. - On the semantic categorical fluency test, the subject named 13 animals in 60 seconds. He named 5 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 6. - On the Number Span forward test, his longest span forward was 4. On the Number Span backward test, his longest span backward was 3. - On the Trail Making Test Part A, his total number of seconds to complete is 150, his number of commission errors is 6, his number of correct lines is 8. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in anxiety, a moderate (significant, but not dramatic) change in elation or euphoria, irritability or lability, a mild (noticeable, but not significant) change in depression or dysphoria. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203983272_01278_MR_Sagittal_MP-Rage_br_raw_20230206170519452_I10181917	On a T1-weighted brain MRI of a 52-year-old female subject, we observed: For the cerebral cortex: - parietal lobe maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the limbic cortex - occipital lobe remains normal, with no signs of tissue loss - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left) and gyrus rectus (normal-to-mild atrophy on the left) - insular cortex remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the temporal lobe For the subcortical structures: - putamen maintains its normal morphology without atrophic features - no signs of atrophy detected in the caudate - normal-to-mild bilateral accumbens atrophy - thalamus appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the pallidum - hippocampus presents with a healthy appearance, free from atrophy - ventral dc presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the basal forebrain - amygdala maintains its normal morphology without atrophic features For the ventricles: - no pathological changes consistent with enlargement noted in the external csf - no pathological changes consistent with enlargement noted in the lateral ventricle - inf. lateral ventricle is free from enlargement or excessive growth - no abnormal enlargement observed in the 3rd ventricle - normal-to-mild enlargement of the 4th ventricle	CN	We have the following subject's personal information: - The subject is a female of 52.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 28. - On the semantic categorical fluency test, the subject named 15 animals in 60 seconds. She named 15 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 22. - On the Number Span forward test, her longest span forward was 8. On the Number Span backward test, her longest span backward was 4. - On the Trail Making Test Part A, her total number of seconds to complete is 38, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 54, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203212277_03771_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451144	On a T1-weighted brain MRI of a 56-year-old female subject, we observed: For the subcortical structures: - no evidence of atrophy or degeneration in the putamen - caudate atrophy (normal-to-mild on the left, normal on the right) - ventral dc presents with a healthy appearance, free from atrophy - accumbens atrophy (mild-to-moderate on the left, normal-to-mild on the right) - no evidence of atrophy or degeneration in the pallidum - amygdala atrophy (severe on the left, moderate on the right) - hippocampus atrophy (severe on the left, normal on the right) - thalamus appears structurally intact with no atrophic changes - the basal forebrain shows no structural abnormalities indicative of atrophy For the cerebral cortex: - no pathological changes consistent with atrophy detected in the occipital lobe - no observable atrophic alterations in the parietal lobe - frontal lobe maintains its normal morphology without atrophic features - limbic cortex atrophy (moderate-to-severe on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (severe atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (normal-to-mild atrophy on the left), parahippocampal gyrus (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the left) and anterior cingulate gyrus (mild atrophy on the left) - insular cortex atrophy (moderate-to-severe on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left), posterior insula (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left) - temporal lobe atrophy (severe on the left, normal on the right), with focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy on the left), middle temporal gyrus (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), temporal pole (severe atrophy on the left) and inf. temporal gyrus (moderate-to-severe atrophy on the left) For the ventricles: - external csf remains within normal size parameters, with no enlargement detected - 3rd ventricle is free from enlargement or excessive growth - no pathological changes consistent with enlargement noted in the 4th ventricle - the lateral ventricle shows no structural abnormalities indicative of enlargement - inf. lateral ventricle enlargement (severe on the left, moderate-to-severe on the right)	SD	We have the following subject's personal information: - The subject is a female of 56.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) - The subject is left-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 0. - On the semantic categorical fluency test, the subject named 3 animals in 60 seconds. She named 0 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 0. - On the Number Span forward test, her longest span forward was 4. On the Number Span backward test, her longest span backward was 6. - On the Trail Making Test Part A, her total number of seconds to complete is 63, her number of commission errors is 1, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 300, her number of commission errors is 3, her number of correct lines is 16. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in appetite and eating. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203977632_02237_MR_Sagittal_MP-Rage_br_raw_20230206180257105_I10182344	On a T1-weighted brain MRI of a 54-year-old male subject, we observed: For the ventricles: - no abnormal enlargement observed in the external csf - no pathological changes consistent with enlargement noted in the 4th ventricle - lateral ventricle remains within normal size parameters, with no enlargement detected - no abnormal enlargement observed in the 3rd ventricle - inf. lateral ventricle appears structurally intact, with no evidence of enlargement For the subcortical structures: - hippocampus remains normal, with no signs of tissue loss - pallidum remains normal, with no signs of tissue loss - basal forebrain remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the accumbens - no signs of atrophy detected in the ventral dc - no pathological changes consistent with atrophy detected in the thalamus - putamen maintains its normal morphology without atrophic features - the caudate shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the amygdala For the cerebral cortex: - no degenerative or atrophic changes noted in the frontal lobe - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in fusiform gyrus (normal-to-mild atrophy on the right) and transverse temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) - the insular cortex shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the limbic cortex - no pathological changes consistent with atrophy detected in the occipital lobe - parietal lobe remains normal, with no signs of tissue loss	CN	We have the following subject's personal information: - The subject is a male of 54.0 years old. - He has 14.0 years of education - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 30. - On the semantic categorical fluency test, the subject named 16 animals in 60 seconds. He named 7 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 22. - On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 5. - On the Trail Making Test Part A, his total number of seconds to complete is 29, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 62, his number of commission errors is 0, his number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203471402_03207_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178329	On a T1-weighted brain MRI of a 72-year-old female subject, we observed: For the subcortical structures: - hippocampus atrophy (normal on the left, severe on the right) - putamen atrophy (normal-to-mild on the left, moderate on the right) - pallidum presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the basal forebrain - no signs of atrophy detected in the ventral dc - severe bilateral amygdala atrophy - no signs of atrophy detected in the thalamus - severe bilateral accumbens atrophy - caudate atrophy (mild on the left, moderate-to-severe on the right) For the cerebral cortex: - the parietal lobe shows no structural abnormalities indicative of atrophy - frontal lobe atrophy (mild on the left, severe on the right), with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy on the left and mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left and severe atrophy on the right), medial frontal cortex (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy on the left and severe atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the right) - temporal lobe atrophy (mild on the left, severe on the right), with focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the right), temporal pole (mild atrophy on the left and severe atrophy on the right), fusiform gyrus (mild atrophy on the right), planum polare (normal-to-mild atrophy on the right) and sup. temporal gyrus (normal-to-mild atrophy on the right) - the occipital lobe shows no structural abnormalities indicative of atrophy - limbic cortex atrophy (mild on the left, moderate-to-severe on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left and severe atrophy on the right), anterior cingulate gyrus (moderate atrophy both left/right), parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the left) - insular cortex atrophy (mild on the left, mild-to-moderate on the right), with focal volume loss observed in the following subregions: anterior insula (severe atrophy both left/right), posterior insula (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and frontal operculum (normal-to-mild atrophy on the right) For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - no enlargement observed in the 4th ventricle - inf. lateral ventricle enlargement (normal on the left, severe on the right) - moderate enlargement of the external csf - no signs of enlargement detected in the lateral ventricle	bvFTD	We have the following subject's personal information: - The subject is a female of 72.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 20. - On the semantic categorical fluency test, the subject named 14 animals in 60 seconds. She named 11 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 0. - On the Number Span forward test, her longest span forward was 5. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 50, her number of commission errors is 1, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 300, her number of commission errors is 4, her number of correct lines is 22. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in appetite and eating, a moderate (significant, but not dramatic) change in anxiety, apathy or indifference, irritability or lability, a mild (noticeable, but not significant) change in agitation or aggression, disinhibition, motor disturbance. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203956632_01235_MR_Sagittal_MP-Rage_br_raw_20230206135959523_I10181113	On a T1-weighted brain MRI of a 55-year-old female subject, we observed: For the cerebral cortex: - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the right) and posterior cingulate gyrus (normal-to-mild atrophy on the left) - occipital lobe maintains its normal morphology without atrophic features - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: triangular inf. frontal gyrus (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus medial segment (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the right) and medial frontal cortex (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the parietal lobe - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: parietal operculum (normal-to-mild atrophy on the left) and central operculum (normal-to-mild atrophy on the left) - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the left) For the subcortical structures: - normal-to-mild bilateral caudate atrophy - normal-to-mild bilateral pallidum atrophy - accumbens appears structurally intact with no atrophic changes - no observable atrophic alterations in the ventral dc - no evidence of atrophy or degeneration in the amygdala - no observable atrophic alterations in the putamen - no degenerative or atrophic changes noted in the hippocampus - no degenerative or atrophic changes noted in the basal forebrain - no signs of atrophy detected in the thalamus For the ventricles: - no enlargement observed in the 3rd ventricle - no enlargement observed in the inf. lateral ventricle - normal-to-mild enlargement of the external csf - 4th ventricle appears structurally intact, with no evidence of enlargement - lateral ventricle enlargement (normal-to-mild on the left, normal on the right)	CN	We have the following subject's personal information: - The subject is a female of 55.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 29. - On the semantic categorical fluency test, the subject named 22 animals in 60 seconds. She named 18 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 10. - On the Number Span forward test, her longest span forward was 9. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 37, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 61, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203094052_02259_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177666	On a T1-weighted brain MRI of a 46-year-old female subject, we observed: For the cerebral cortex: - the occipital lobe shows no structural abnormalities indicative of atrophy - limbic cortex appears structurally intact with no atrophic changes, with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right) - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left) and precuneus (normal-to-mild atrophy on the right) - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the left) and inf. temporal gyrus (normal-to-mild atrophy on the right) - no signs of atrophy detected in the insular cortex - frontal lobe presents with a healthy appearance, free from atrophy For the ventricles: - no pathological changes consistent with enlargement noted in the external csf - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - no observable enlargement or abnormal growth in the lateral ventricle - 3rd ventricle maintains its normal volume without signs of enlargement - no pathological changes consistent with enlargement noted in the 4th ventricle For the subcortical structures: - no evidence of atrophy or degeneration in the hippocampus - amygdala atrophy (normal on the left, normal-to-mild on the right) - accumbens atrophy (normal-to-mild on the left, normal on the right) - no pathological changes consistent with atrophy detected in the caudate - ventral dc remains normal, with no signs of tissue loss - putamen presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the pallidum - no observable atrophic alterations in the thalamus - no degenerative or atrophic changes noted in the basal forebrain	CN	We have the following subject's personal information: - The subject is a female of 46.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 30. - On the semantic categorical fluency test, the subject named 23 animals in 60 seconds. She named 14 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 26. - On the Number Span forward test, her longest span forward was 5. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 16, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 47, her number of commission errors is 0, her number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in nighttime behaviors. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203966778_01876_MR_Sagittal_MP-Rage_br_raw_20230206175323985_I10182277	On a T1-weighted brain MRI of a 71-year-old male subject, we observed: For the subcortical structures: - basal forebrain presents with a healthy appearance, free from atrophy - caudate atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral accumbens atrophy - hippocampus maintains its normal morphology without atrophic features - thalamus atrophy (normal on the left, normal-to-mild on the right) - normal-to-mild bilateral ventral dc atrophy - pallidum presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the amygdala - putamen atrophy (normal on the left, normal-to-mild on the right) For the cerebral cortex: - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right) and posterior orbital gyrus (normal-to-mild atrophy on the left) - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: lingual gyrus (normal-to-mild atrophy on the right), sup. occipital gyrus (normal-to-mild atrophy on the right), occipital pole (normal-to-mild atrophy both left/right) and inf. occipital gyrus (normal-to-mild atrophy on the right) - no pathological changes consistent with atrophy detected in the parietal lobe - limbic cortex maintains its normal morphology without atrophic features - the insular cortex shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the temporal lobe For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - no signs of enlargement detected in the external csf - no pathological changes consistent with enlargement noted in the 3rd ventricle - normal-to-mild bilateral inf. lateral ventricle enlargement	bvFTD	We have the following subject's personal information: - The subject is a male of 71.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 30. - On the semantic categorical fluency test, the subject named 19 animals in 60 seconds. He named 15 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 24. - On the Number Span forward test, his longest span forward was 4. On the Number Span backward test, his longest span backward was 5. - On the Trail Making Test Part A, his total number of seconds to complete is 30, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 116, his number of commission errors is 0, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in agitation or aggression, elation or euphoria, apathy or indifference, disinhibition, nighttime behaviors, appetite and eating, a moderate (significant, but not dramatic) change in delusions, motor disturbance. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203679999_01997_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10449529	On a T1-weighted brain MRI of a 71-year-old male subject, we observed: For the ventricles: - lateral ventricle enlargement (normal-to-mild on the left, mild on the right) - no pathological changes consistent with enlargement noted in the 4th ventricle - inf. lateral ventricle enlargement (normal-to-mild on the left, moderate on the right) - normal-to-mild enlargement of the external csf - normal-to-mild enlargement of the 3rd ventricle For the cerebral cortex: - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right) and precentral gyrus medial segment (normal-to-mild atrophy both left/right) - no observable atrophic alterations in the temporal lobe - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (mild atrophy on the right) and postcentral gyrus (normal-to-mild atrophy on the right) - no degenerative or atrophic changes noted in the occipital lobe - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), central operculum (normal-to-mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the right) - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) For the subcortical structures: - no observable atrophic alterations in the putamen - no observable atrophic alterations in the accumbens - thalamus atrophy (mild on the left, normal-to-mild on the right) - ventral dc maintains its normal morphology without atrophic features - normal-to-mild bilateral pallidum atrophy - the amygdala shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the caudate - normal-to-mild bilateral hippocampus atrophy - no pathological changes consistent with atrophy detected in the basal forebrain	bvFTD	We have the following subject's personal information: - The subject is a male of 71.0 years old. - He has 15.0 years of education - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 10 animals in 60 seconds. He named 4 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 5. - On the Number Span forward test, his longest span forward was 5. On the Number Span backward test, his longest span backward was 3. - On the Trail Making Test Part A, his total number of seconds to complete is 111, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 300, his number of commission errors is 8, his number of correct lines is 2. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in disinhibition, irritability or lability, nighttime behaviors. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. His standard CDR sum of boxes is 12.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203798227_03729_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10451111	On a T1-weighted brain MRI of a 56-year-old female subject, we observed: For the ventricles: - mild-to-moderate enlargement of the 3rd ventricle - severe bilateral inf. lateral ventricle enlargement - lateral ventricle enlargement (severe on the left, moderate on the right) - normal-to-mild enlargement of the external csf - no pathological changes consistent with enlargement noted in the 4th ventricle For the subcortical structures: - thalamus atrophy (mild on the left, normal on the right) - no signs of atrophy detected in the basal forebrain - severe bilateral amygdala atrophy - ventral dc presents with a healthy appearance, free from atrophy - accumbens atrophy (severe on the left, normal-to-mild on the right) - hippocampus atrophy (severe on the left, mild on the right) - putamen atrophy (severe on the left, mild on the right) - caudate atrophy (severe on the left, normal-to-mild on the right) - pallidum atrophy (mild-to-moderate on the left, normal-to-mild on the right) For the cerebral cortex: - no evidence of atrophy or degeneration in the occipital lobe - the parietal lobe shows no structural abnormalities indicative of atrophy - limbic cortex atrophy (moderate-to-severe on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - temporal lobe atrophy (severe on the left, moderate on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), inf. temporal gyrus (severe atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), temporal pole (severe atrophy both left/right), planum polare (mild atrophy on the left) and sup. temporal gyrus (mild atrophy on the left) - frontal lobe atrophy (moderate on the left, normal on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus (mild atrophy on the left), sup. frontal gyrus medial segment (mild atrophy on the left) and precentral gyrus medial segment (normal-to-mild atrophy on the left) - insular cortex atrophy (moderate-to-severe on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), central operculum (normal-to-mild atrophy on the left), frontal operculum (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the right)	SD	We have the following subject's personal information: - The subject is a female of 56.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 8. - On the Number Span forward test, her longest span forward was 3. - On the Trail Making Test Part A, her total number of seconds to complete is 88, her number of commission errors is 0, her number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in disinhibition, a moderate (significant, but not dramatic) change in anxiety, motor disturbance, a mild (noticeable, but not significant) change in apathy or indifference, nighttime behaviors. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203966778_01876_MR_Sagittal_MP-Rage_br_raw_20230206175323985_I10182277	On a T1-weighted brain MRI of a 71-year-old male subject, we observed: For the subcortical structures: - no degenerative or atrophic changes noted in the basal forebrain - no observable atrophic alterations in the amygdala - normal-to-mild bilateral accumbens atrophy - hippocampus maintains its normal morphology without atrophic features - pallidum appears structurally intact with no atrophic changes - normal-to-mild bilateral ventral dc atrophy - caudate atrophy (normal on the left, normal-to-mild on the right) - thalamus atrophy (normal on the left, normal-to-mild on the right) - putamen atrophy (normal on the left, normal-to-mild on the right) For the cerebral cortex: - occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: lingual gyrus (normal-to-mild atrophy on the right), sup. occipital gyrus (normal-to-mild atrophy on the right), occipital pole (normal-to-mild atrophy both left/right) and inf. occipital gyrus (normal-to-mild atrophy on the right) - no pathological changes consistent with atrophy detected in the temporal lobe - insular cortex remains normal, with no signs of tissue loss - limbic cortex appears structurally intact with no atrophic changes - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right) and posterior orbital gyrus (normal-to-mild atrophy on the left) - parietal lobe appears structurally intact with no atrophic changes For the ventricles: - no pathological changes consistent with enlargement noted in the 3rd ventricle - normal-to-mild bilateral inf. lateral ventricle enlargement - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - no pathological changes consistent with enlargement noted in the 4th ventricle - no observable enlargement or abnormal growth in the external csf	bvFTD	We have the following subject's personal information: - The subject is a male of 71.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 30. - On the semantic categorical fluency test, the subject named 19 animals in 60 seconds. He named 15 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 24. - On the Number Span forward test, his longest span forward was 4. On the Number Span backward test, his longest span backward was 5. - On the Trail Making Test Part A, his total number of seconds to complete is 30, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 116, his number of commission errors is 0, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in agitation or aggression, elation or euphoria, apathy or indifference, disinhibition, nighttime behaviors, appetite and eating, a moderate (significant, but not dramatic) change in delusions, motor disturbance. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203120483_03382_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450642	On a T1-weighted brain MRI of a 64-year-old male subject, we observed: For the subcortical structures: - no pathological changes consistent with atrophy detected in the pallidum - no pathological changes consistent with atrophy detected in the putamen - no degenerative or atrophic changes noted in the thalamus - no evidence of atrophy or degeneration in the basal forebrain - hippocampus remains normal, with no signs of tissue loss - amygdala appears structurally intact with no atrophic changes - normal-to-mild bilateral accumbens atrophy - ventral dc presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the caudate For the cerebral cortex: - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the right), posterior insula (normal-to-mild atrophy on the left) and central operculum (normal-to-mild atrophy on the left) - occipital lobe maintains its normal morphology without atrophic features - parietal lobe maintains its normal morphology without atrophic features - temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the right) and transverse temporal gyrus (normal-to-mild atrophy on the right) - mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right) and posterior cingulate gyrus (normal-to-mild atrophy on the left) For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (mild on the left, mild-to-moderate on the right) - severe enlargement of the 4th ventricle - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - no observable enlargement or abnormal growth in the external csf	bvFTD	We have the following subject's personal information: - The subject is a male of 64.0 years old. - He has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 19 animals in 60 seconds. He named 16 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 8. - On the Number Span forward test, his longest span forward was 5. On the Number Span backward test, his longest span backward was 2. - On the Trail Making Test Part A, his total number of seconds to complete is 65, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 149, his number of commission errors is 0, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in apathy or indifference, irritability or lability, nighttime behaviors, appetite and eating, a mild (noticeable, but not significant) change in hallucinations, agitation or aggression, depression or dysphoria, anxiety, disinhibition. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203440939_01934_MR_Sagittal_MP-Rage_br_raw_20230209094057164_I10183241	On a T1-weighted brain MRI of a 55-year-old male subject, we observed: For the cerebral cortex: - no evidence of atrophy or degeneration in the occipital lobe - parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: postcentral gyrus medial segment (normal-to-mild atrophy on the right) and sup. parietal lobule (normal-to-mild atrophy both left/right) - no signs of atrophy detected in the insular cortex - limbic cortex appears structurally intact with no atrophic changes - no observable atrophic alterations in the temporal lobe - no evidence of atrophy or degeneration in the frontal lobe For the subcortical structures: - no observable atrophic alterations in the hippocampus - no observable atrophic alterations in the pallidum - thalamus appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the putamen - basal forebrain presents with a healthy appearance, free from atrophy - accumbens remains normal, with no signs of tissue loss - caudate presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the ventral dc - no pathological changes consistent with atrophy detected in the amygdala For the ventricles: - no enlargement observed in the 3rd ventricle - no enlargement observed in the inf. lateral ventricle - no signs of enlargement detected in the 4th ventricle - lateral ventricle maintains its normal volume without signs of enlargement - no observable enlargement or abnormal growth in the external csf	bvFTD	We have the following subject's personal information: - The subject is a male of 55.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 29. - On the semantic categorical fluency test, the subject named 14 animals in 60 seconds. He named 10 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 10. - On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 6. - On the Trail Making Test Part A, his total number of seconds to complete is 23, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 50, his number of commission errors is 0, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in anxiety, a mild (noticeable, but not significant) change in depression or dysphoria, apathy or indifference, nighttime behaviors. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203912538_03831_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047790	On a T1-weighted brain MRI of a 55-year-old female subject, we observed: For the ventricles: - 3rd ventricle appears structurally intact, with no evidence of enlargement - no observable enlargement or abnormal growth in the lateral ventricle - the 4th ventricle shows no structural abnormalities indicative of enlargement - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the external csf For the cerebral cortex: - no degenerative or atrophic changes noted in the occipital lobe - no observable atrophic alterations in the temporal lobe - normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy on the right) and central operculum (mild atrophy on the left) - normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy both left/right) and anterior orbital gyrus (normal-to-mild atrophy on the right) - no evidence of atrophy or degeneration in the parietal lobe - limbic cortex remains normal, with no signs of tissue loss For the subcortical structures: - the caudate shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the thalamus - the amygdala shows no structural abnormalities indicative of atrophy - accumbens remains normal, with no signs of tissue loss - basal forebrain remains normal, with no signs of tissue loss - hippocampus appears structurally intact with no atrophic changes - mild bilateral putamen atrophy - normal-to-mild bilateral pallidum atrophy - the ventral dc shows no structural abnormalities indicative of atrophy	PNFA	We have the following subject's personal information: - The subject is a female of 55.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 27. - On the semantic categorical fluency test, the subject named 17 animals in 60 seconds. She named 15 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 15. - On the Number Span forward test, her longest span forward was 4. On the Number Span backward test, her longest span backward was 4. - On the Trail Making Test Part A, her total number of seconds to complete is 51, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 142, her number of commission errors is 0, her number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in depression or dysphoria. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203391632_03239_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10178045	On a T1-weighted brain MRI of a 41-year-old female subject, we observed: For the ventricles: - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - no abnormal enlargement observed in the 4th ventricle - no pathological changes consistent with enlargement noted in the lateral ventricle - no pathological changes consistent with enlargement noted in the external csf - 3rd ventricle appears structurally intact, with no evidence of enlargement For the cerebral cortex: - temporal lobe presents with a healthy appearance, free from atrophy - frontal lobe maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the limbic cortex - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (mild-to-moderate atrophy on the left) - the parietal lobe shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the insular cortex For the subcortical structures: - no evidence of atrophy or degeneration in the amygdala - thalamus maintains its normal morphology without atrophic features - ventral dc appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the pallidum - no signs of atrophy detected in the caudate - accumbens presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the hippocampus - no pathological changes consistent with atrophy detected in the putamen - no observable atrophic alterations in the basal forebrain	CN	We have the following subject's personal information: - The subject is a female of 41.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 28. - On the semantic categorical fluency test, the subject named 21 animals in 60 seconds. She named 20 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 28. - On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 20, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 60, her number of commission errors is 1, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203748920_03024_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176803	On a T1-weighted brain MRI of a 64-year-old male subject, we observed: For the cerebral cortex: - no pathological changes consistent with atrophy detected in the parietal lobe - temporal lobe atrophy (severe on the left, normal on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left), planum polare (normal-to-mild atrophy on the left), middle temporal gyrus (mild-to-moderate atrophy on the left), sup. temporal gyrus (normal-to-mild atrophy on the left), temporal pole (severe atrophy on the left) and inf. temporal gyrus (mild atrophy on the left) - insular cortex atrophy (moderate on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the left) and posterior insula (mild atrophy on the left) - occipital lobe presents with a healthy appearance, free from atrophy - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left) and subcallosal area (normal-to-mild atrophy on the left) - limbic cortex atrophy (moderate on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (moderate-to-severe atrophy on the left), parahippocampal gyrus (mild-to-moderate atrophy on the left) and anterior cingulate gyrus (mild atrophy on the left) For the ventricles: - inf. lateral ventricle enlargement (severe on the left, normal on the right) - normal-to-mild enlargement of the external csf - no abnormal enlargement observed in the lateral ventricle - no pathological changes consistent with enlargement noted in the 3rd ventricle - 4th ventricle is free from enlargement or excessive growth For the subcortical structures: - putamen atrophy (normal-to-mild on the left, normal on the right) - amygdala atrophy (severe on the left, normal on the right) - thalamus appears structurally intact with no atrophic changes - hippocampus atrophy (severe on the left, normal on the right) - pallidum atrophy (normal-to-mild on the left, normal on the right) - accumbens atrophy (moderate on the left, normal-to-mild on the right) - caudate remains normal, with no signs of tissue loss - no observable atrophic alterations in the basal forebrain - the ventral dc shows no structural abnormalities indicative of atrophy	SD	We have the following subject's personal information: - The subject is a male of 64.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 21. - On the semantic categorical fluency test, the subject named 14 animals in 60 seconds. He named 8 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 8. - On the Number Span forward test, his longest span forward was 6. On the Number Span backward test, his longest span backward was 4. - On the Trail Making Test Part A, his total number of seconds to complete is 25, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 66, his number of commission errors is 0, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in irritability or lability. - On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on behavior, comportment, and personality, corresponding to no impairment.
FTLD_203573727_02727_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176961	On a T1-weighted brain MRI of a 67-year-old male subject, we observed: For the cerebral cortex: - insular cortex atrophy (normal-to-mild on the left, mild-to-moderate on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the right) and parietal operculum (normal-to-mild atrophy both left/right) - temporal lobe atrophy (normal-to-mild on the left, mild-to-moderate on the right), with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy both left/right) and temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right) - occipital lobe maintains its normal morphology without atrophic features - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the right) - frontal lobe atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy both left/right) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) - parietal lobe maintains its normal morphology without atrophic features For the subcortical structures: - the basal forebrain shows no structural abnormalities indicative of atrophy - thalamus atrophy (normal on the left, normal-to-mild on the right) - amygdala atrophy (mild on the left, severe on the right) - ventral dc atrophy (normal on the left, normal-to-mild on the right) - hippocampus atrophy (normal-to-mild on the left, moderate on the right) - caudate atrophy (moderate on the left, severe on the right) - severe bilateral accumbens atrophy - pallidum atrophy (normal-to-mild on the left, mild on the right) - putamen atrophy (moderate on the left, moderate-to-severe on the right) For the ventricles: - no enlargement observed in the 4th ventricle - moderate-to-severe enlargement of the external csf - lateral ventricle enlargement (normal on the left, normal-to-mild on the right) - inf. lateral ventricle enlargement (moderate on the left, severe on the right) - 3rd ventricle is free from enlargement or excessive growth	bvFTD	We have the following subject's personal information: - The subject is a male of 67.0 years old. - He has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 25. - On the semantic categorical fluency test, the subject named 8 animals in 60 seconds. He named 5 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 0. - On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 4. - On the Trail Making Test Part A, his total number of seconds to complete is 96, his number of commission errors is 3, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in agitation or aggression, apathy or indifference, irritability or lability, motor disturbance, nighttime behaviors, appetite and eating, a mild (noticeable, but not significant) change in depression or dysphoria, anxiety. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on behavior, comportment, and personality, corresponding to moderate impairment.
FTLD_203403697_01790_MR_Sagittal_MP-Rage_br_raw_20230206174835442_I10182241	On a T1-weighted brain MRI of a 69-year-old female subject, we observed: For the ventricles: - lateral ventricle enlargement (normal-to-mild on the left, mild on the right) - moderate-to-severe enlargement of the external csf - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (normal on the left, mild on the right) - the 4th ventricle shows no structural abnormalities indicative of enlargement For the subcortical structures: - thalamus atrophy (normal-to-mild on the left, severe on the right) - ventral dc atrophy (normal on the left, mild on the right) - caudate atrophy (mild on the left, severe on the right) - basal forebrain appears structurally intact with no atrophic changes - pallidum atrophy (normal-to-mild on the left, severe on the right) - amygdala atrophy (normal-to-mild on the left, mild on the right) - hippocampus atrophy (normal-to-mild on the left, severe on the right) - putamen atrophy (normal-to-mild on the left, severe on the right) - accumbens atrophy (mild on the left, moderate-to-severe on the right) For the cerebral cortex: - insular cortex atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the right), posterior insula (normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the right) - frontal lobe atrophy (normal-to-mild on the left, severe on the right), with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy on the right), gyrus rectus (mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus (mild-to-moderate atrophy on the right) - parietal lobe atrophy (normal on the left, moderate on the right), with focal volume loss observed in the following subregions: angular gyrus (mild-to-moderate atrophy on the right), postcentral gyrus (normal-to-mild atrophy on the left), postcentral gyrus medial segment (normal-to-mild atrophy on the right), precuneus (normal-to-mild atrophy on the right) and sup. parietal lobule (normal-to-mild atrophy on the right) - limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy both left/right) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy on the left), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right) and inf. temporal gyrus (mild atrophy on the right) - no signs of atrophy detected in the occipital lobe	bvFTD	We have the following subject's personal information: - The subject is a female of 69.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 13 animals in 60 seconds. She named 9 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 12. - On the Number Span forward test, her longest span forward was 4. On the Number Span backward test, her longest span backward was 4. - On the Trail Making Test Part A, her total number of seconds to complete is 33, her number of commission errors is 1, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 300, her number of commission errors is 8, her number of correct lines is 3. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in appetite and eating, a moderate (significant, but not dramatic) change in hallucinations. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203940015_02514_MR_Sagittal_MP-Rage_br_raw_20230209102908496_I10183491	On a T1-weighted brain MRI of a 57-year-old female subject, we observed: For the cerebral cortex: - occipital lobe appears structurally intact with no atrophic changes - insular cortex appears structurally intact with no atrophic changes - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left) - temporal lobe appears structurally intact with no atrophic changes - frontal lobe maintains its normal morphology without atrophic features - parietal lobe remains normal, with no signs of tissue loss For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - no pathological changes consistent with enlargement noted in the lateral ventricle - no enlargement observed in the inf. lateral ventricle - external csf maintains its normal volume without signs of enlargement - no abnormal enlargement observed in the 3rd ventricle For the subcortical structures: - basal forebrain remains normal, with no signs of tissue loss - the accumbens shows no structural abnormalities indicative of atrophy - pallidum maintains its normal morphology without atrophic features - the hippocampus shows no structural abnormalities indicative of atrophy - the putamen shows no structural abnormalities indicative of atrophy - caudate presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the thalamus - no observable atrophic alterations in the amygdala - no evidence of atrophy or degeneration in the ventral dc	CN	We have the following subject's personal information: - The subject is a female of 57.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 29. - On the semantic categorical fluency test, the subject named 18 animals in 60 seconds. She named 17 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 21. - On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 4. - On the Trail Making Test Part A, her total number of seconds to complete is 16, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 46, her number of commission errors is 0, her number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in depression or dysphoria, anxiety, irritability or lability. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203681967_01768_MR_Sagittal_MP-Rage_br_raw_20230206174731756_I10182233	On a T1-weighted brain MRI of a 59-year-old female subject, we observed: For the ventricles: - normal-to-mild enlargement of the external csf - no signs of enlargement detected in the lateral ventricle - 4th ventricle remains within normal size parameters, with no enlargement detected - no observable enlargement or abnormal growth in the 3rd ventricle - no observable enlargement or abnormal growth in the inf. lateral ventricle For the cerebral cortex: - normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy both left/right), sup. parietal lobule (normal-to-mild atrophy both left/right) and supramarginal gyrus (normal-to-mild atrophy on the left) - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left), posterior cingulate gyrus (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) - occipital lobe appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the temporal lobe - insular cortex atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy on the left), central operculum (normal-to-mild atrophy on the right), parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the right) - frontal lobe presents with a healthy appearance, free from atrophy For the subcortical structures: - hippocampus maintains its normal morphology without atrophic features - normal-to-mild bilateral thalamus atrophy - putamen atrophy (normal on the left, normal-to-mild on the right) - accumbens atrophy (normal-to-mild on the left, normal on the right) - pallidum atrophy (normal on the left, normal-to-mild on the right) - caudate atrophy (normal on the left, normal-to-mild on the right) - no observable atrophic alterations in the amygdala - no observable atrophic alterations in the basal forebrain - no pathological changes consistent with atrophy detected in the ventral dc	CN	We have the following subject's personal information: - The subject is a female of 59.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) - The subject is left-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 20 animals in 60 seconds. She named 15 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 17. - On the Number Span forward test, her longest span forward was 8. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 23, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 74, her number of commission errors is 0, her number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in irritability or lability. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203300760_03060_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178272	On a T1-weighted brain MRI of a 59-year-old male subject, we observed: For the cerebral cortex: - the parietal lobe shows no structural abnormalities indicative of atrophy - temporal lobe atrophy (severe on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (severe atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left), middle temporal gyrus (mild atrophy on the left) and sup. temporal gyrus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the frontal lobe - limbic cortex atrophy (mild-to-moderate on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left), anterior cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (mild-to-moderate atrophy on the left) - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left) and posterior insula (normal-to-mild atrophy on the left) - occipital lobe maintains its normal morphology without atrophic features For the subcortical structures: - caudate atrophy (normal-to-mild on the left, normal on the right) - normal-to-mild bilateral pallidum atrophy - accumbens atrophy (normal-to-mild on the left, normal on the right) - hippocampus atrophy (mild on the left, normal on the right) - ventral dc atrophy (normal on the left, normal-to-mild on the right) - putamen atrophy (normal-to-mild on the left, normal on the right) - basal forebrain appears structurally intact with no atrophic changes - thalamus atrophy (normal-to-mild on the left, normal on the right) - amygdala atrophy (severe on the left, normal on the right) For the ventricles: - the 3rd ventricle shows no structural abnormalities indicative of enlargement - no observable enlargement or abnormal growth in the 4th ventricle - inf. lateral ventricle enlargement (severe on the left, normal on the right) - lateral ventricle appears structurally intact, with no evidence of enlargement - mild enlargement of the external csf	SD	We have the following subject's personal information: - The subject is a male of 59.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 3. - On the semantic categorical fluency test, the subject named 4 animals in 60 seconds. He named 5 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 7. - On the Number Span forward test, his longest span forward was 9. On the Number Span backward test, his longest span backward was 6. - On the Trail Making Test Part A, his total number of seconds to complete is 24, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 82, his number of commission errors is 1, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in agitation or aggression, depression or dysphoria, anxiety, apathy or indifference, irritability or lability, appetite and eating.
FTLD_203901165_02560_MR_Sagittal_MP-Rage_br_raw_20230209103425185_I10183512	On a T1-weighted brain MRI of a 36-year-old female subject, we observed: For the subcortical structures: - thalamus remains normal, with no signs of tissue loss - putamen appears structurally intact with no atrophic changes - accumbens appears structurally intact with no atrophic changes - normal-to-mild bilateral caudate atrophy - the basal forebrain shows no structural abnormalities indicative of atrophy - pallidum maintains its normal morphology without atrophic features - no evidence of atrophy or degeneration in the amygdala - hippocampus atrophy (normal on the left, normal-to-mild on the right) - ventral dc presents with a healthy appearance, free from atrophy For the cerebral cortex: - no observable atrophic alterations in the insular cortex - temporal lobe presents with a healthy appearance, free from atrophy - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal pole (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy both left/right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right) and anterior orbital gyrus (normal-to-mild atrophy on the left) - no evidence of atrophy or degeneration in the limbic cortex - parietal lobe presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the occipital lobe For the ventricles: - external csf maintains its normal volume without signs of enlargement - lateral ventricle remains within normal size parameters, with no enlargement detected - the 3rd ventricle shows no structural abnormalities indicative of enlargement - no enlargement observed in the inf. lateral ventricle - 4th ventricle appears structurally intact, with no evidence of enlargement	CN	We have the following subject's personal information: - The subject is a female of 36.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 20 animals in 60 seconds. She named 16 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 17. - On the Number Span forward test, her longest span forward was 8. On the Number Span backward test, her longest span backward was 6. - On the Trail Making Test Part A, her total number of seconds to complete is 13, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 33, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203391632_03239_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10178045	On a T1-weighted brain MRI of a 41-year-old female subject, we observed: For the cerebral cortex: - no observable atrophic alterations in the parietal lobe - no pathological changes consistent with atrophy detected in the temporal lobe - insular cortex appears structurally intact with no atrophic changes - limbic cortex remains normal, with no signs of tissue loss - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (mild-to-moderate atrophy on the left) - frontal lobe appears structurally intact with no atrophic changes For the subcortical structures: - no evidence of atrophy or degeneration in the putamen - amygdala appears structurally intact with no atrophic changes - the hippocampus shows no structural abnormalities indicative of atrophy - thalamus presents with a healthy appearance, free from atrophy - accumbens appears structurally intact with no atrophic changes - ventral dc remains normal, with no signs of tissue loss - pallidum presents with a healthy appearance, free from atrophy - basal forebrain maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the caudate For the ventricles: - the 3rd ventricle shows no structural abnormalities indicative of enlargement - no observable enlargement or abnormal growth in the inf. lateral ventricle - no pathological changes consistent with enlargement noted in the external csf - no signs of enlargement detected in the lateral ventricle - 4th ventricle maintains its normal volume without signs of enlargement	CN	We have the following subject's personal information: - The subject is a female of 41.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 28. - On the semantic categorical fluency test, the subject named 21 animals in 60 seconds. She named 20 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 28. - On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 20, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 60, her number of commission errors is 1, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203316074_03471_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450814	On a T1-weighted brain MRI of a 54-year-old female subject, we observed: For the subcortical structures: - no degenerative or atrophic changes noted in the putamen - ventral dc maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the hippocampus - no signs of atrophy detected in the thalamus - no evidence of atrophy or degeneration in the accumbens - no signs of atrophy detected in the pallidum - amygdala maintains its normal morphology without atrophic features - the basal forebrain shows no structural abnormalities indicative of atrophy - caudate appears structurally intact with no atrophic changes For the ventricles: - no observable enlargement or abnormal growth in the 4th ventricle - external csf is free from enlargement or excessive growth - no abnormal enlargement observed in the 3rd ventricle - no observable enlargement or abnormal growth in the lateral ventricle - no abnormal enlargement observed in the inf. lateral ventricle For the cerebral cortex: - the temporal lobe shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the limbic cortex - no signs of atrophy detected in the parietal lobe - insular cortex maintains its normal morphology without atrophic features - occipital lobe remains normal, with no signs of tissue loss - frontal lobe presents with a healthy appearance, free from atrophy	CN	We have the following subject's personal information: - The subject is a female of 54.0 years old. - She has 20.0 years of education (equivalent to doctorate) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 28. - On the semantic categorical fluency test, the subject named 23 animals in 60 seconds. She named 21 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 17. - On the Number Span forward test, her longest span forward was 8. On the Number Span backward test, her longest span backward was 6. - On the Trail Making Test Part A, her total number of seconds to complete is 23, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 54, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203103542_03240_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177115	On a T1-weighted brain MRI of a 78-year-old female subject, we observed: For the cerebral cortex: - occipital lobe maintains its normal morphology without atrophic features - limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) - parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy on the right) - frontal lobe atrophy (severe on the left, normal on the right), with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), supplementary motor cortex (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the right), middle frontal gyrus (mild-to-moderate atrophy on the left), sup. frontal gyrus (mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) - insular cortex atrophy (mild-to-moderate on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right), posterior insula (normal-to-mild atrophy on the left), frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left) - the temporal lobe shows no structural abnormalities indicative of atrophy For the subcortical structures: - putamen atrophy (mild-to-moderate on the left, normal on the right) - thalamus atrophy (normal-to-mild on the left, normal on the right) - no evidence of atrophy or degeneration in the amygdala - no signs of atrophy detected in the basal forebrain - accumbens atrophy (mild-to-moderate on the left, mild on the right) - caudate atrophy (severe on the left, mild on the right) - hippocampus atrophy (normal-to-mild on the left, normal on the right) - pallidum atrophy (normal-to-mild on the left, normal on the right) - ventral dc remains normal, with no signs of tissue loss For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - inf. lateral ventricle enlargement (mild on the left, normal on the right) - normal-to-mild enlargement of the 3rd ventricle - lateral ventricle enlargement (mild on the left, normal-to-mild on the right) - normal-to-mild enlargement of the external csf	bvFTD	We have the following subject's personal information: - The subject is a female of 78.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 27. - On the semantic categorical fluency test, the subject named 4 animals in 60 seconds. She named 5 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 0. - On the Number Span forward test, her longest span forward was 5. On the Number Span backward test, her longest span backward was 2. - On the Trail Making Test Part A, her total number of seconds to complete is 150, her number of commission errors is 1, her number of correct lines is 9. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in apathy or indifference, disinhibition, appetite and eating. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 6.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203391632_03239_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10178045	On a T1-weighted brain MRI of a 41-year-old female subject, we observed: For the cerebral cortex: - no pathological changes consistent with atrophy detected in the limbic cortex - no pathological changes consistent with atrophy detected in the frontal lobe - no signs of atrophy detected in the temporal lobe - insular cortex remains normal, with no signs of tissue loss - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (mild-to-moderate atrophy on the left) - no signs of atrophy detected in the parietal lobe For the ventricles: - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - 3rd ventricle is free from enlargement or excessive growth - external csf remains within normal size parameters, with no enlargement detected - lateral ventricle appears structurally intact, with no evidence of enlargement - 4th ventricle maintains its normal volume without signs of enlargement For the subcortical structures: - accumbens appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the caudate - amygdala appears structurally intact with no atrophic changes - the basal forebrain shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the hippocampus - no evidence of atrophy or degeneration in the putamen - no degenerative or atrophic changes noted in the pallidum - ventral dc appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the thalamus	CN	We have the following subject's personal information: - The subject is a female of 41.0 years old. - She has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 28. - On the semantic categorical fluency test, the subject named 21 animals in 60 seconds. She named 20 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 28. - On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 20, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 60, her number of commission errors is 1, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203808293_02390_MR_Sagittal_MP-Rage_br_raw_20230206180655212_I10182372	On a T1-weighted brain MRI of a 57-year-old female subject, we observed: For the subcortical structures: - the accumbens shows no structural abnormalities indicative of atrophy - pallidum appears structurally intact with no atrophic changes - ventral dc remains normal, with no signs of tissue loss - putamen appears structurally intact with no atrophic changes - thalamus appears structurally intact with no atrophic changes - hippocampus presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the amygdala - basal forebrain appears structurally intact with no atrophic changes - caudate appears structurally intact with no atrophic changes For the ventricles: - no enlargement observed in the 3rd ventricle - no observable enlargement or abnormal growth in the 4th ventricle - the external csf shows no structural abnormalities indicative of enlargement - no observable enlargement or abnormal growth in the inf. lateral ventricle - no signs of enlargement detected in the lateral ventricle For the cerebral cortex: - the occipital lobe shows no structural abnormalities indicative of atrophy - frontal lobe remains normal, with no signs of tissue loss - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy on the left), planum polare (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the right) and inf. temporal gyrus (normal-to-mild atrophy on the left) - limbic cortex remains normal, with no signs of tissue loss - parietal lobe appears structurally intact with no atrophic changes - the insular cortex shows no structural abnormalities indicative of atrophy	CN	We have the following subject's personal information: - The subject is a female of 57.0 years old. - She has 14.0 years of education - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 28. - On the semantic categorical fluency test, the subject named 18 animals in 60 seconds. She named 12 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 15. - On the Number Span forward test, her longest span forward was 4. On the Number Span backward test, her longest span backward was 3. - On the Trail Making Test Part A, her total number of seconds to complete is 26, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 74, her number of commission errors is 2, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203974853_02357_MR_Sagittal_MP-Rage_br_raw_20230206160041790_I10181513	On a T1-weighted brain MRI of a 43-year-old female subject, we observed: For the ventricles: - no signs of enlargement detected in the inf. lateral ventricle - 4th ventricle is free from enlargement or excessive growth - lateral ventricle appears structurally intact, with no evidence of enlargement - 3rd ventricle maintains its normal volume without signs of enlargement - mild enlargement of the external csf For the subcortical structures: - the ventral dc shows no structural abnormalities indicative of atrophy - caudate atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the thalamus - no signs of atrophy detected in the hippocampus - putamen atrophy (normal-to-mild on the left, normal on the right) - no observable atrophic alterations in the pallidum - no observable atrophic alterations in the basal forebrain - no degenerative or atrophic changes noted in the accumbens - no evidence of atrophy or degeneration in the amygdala For the cerebral cortex: - occipital lobe presents with a healthy appearance, free from atrophy - the limbic cortex shows no structural abnormalities indicative of atrophy - the parietal lobe shows no structural abnormalities indicative of atrophy - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy both left/right) - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), temporal pole (normal-to-mild atrophy on the left), fusiform gyrus (normal-to-mild atrophy on the right) and inf. temporal gyrus (normal-to-mild atrophy on the right) - frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the right)	CN	We have the following subject's personal information: - The subject is a female of 43.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 28. - On the semantic categorical fluency test, the subject named 26 animals in 60 seconds. She named 16 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 30. - On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 22, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 48, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203266648_01846_MR_Sagittal_MP-Rage_br_raw_20230206151900156_I10181365	On a T1-weighted brain MRI of a 55-year-old female subject, we observed: For the subcortical structures: - no pathological changes consistent with atrophy detected in the accumbens - no pathological changes consistent with atrophy detected in the amygdala - no pathological changes consistent with atrophy detected in the hippocampus - putamen remains normal, with no signs of tissue loss - no observable atrophic alterations in the caudate - pallidum remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the basal forebrain - normal-to-mild bilateral thalamus atrophy - normal-to-mild bilateral ventral dc atrophy For the ventricles: - no pathological changes consistent with enlargement noted in the 4th ventricle - no observable enlargement or abnormal growth in the external csf - 3rd ventricle is free from enlargement or excessive growth - no enlargement observed in the lateral ventricle - no observable enlargement or abnormal growth in the inf. lateral ventricle For the cerebral cortex: - limbic cortex appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the occipital lobe - no degenerative or atrophic changes noted in the parietal lobe - no observable atrophic alterations in the frontal lobe - no signs of atrophy detected in the insular cortex - the temporal lobe shows no structural abnormalities indicative of atrophy	CN	We have the following subject's personal information: - The subject is a female of 55.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 30. - On the semantic categorical fluency test, the subject named 23 animals in 60 seconds. She named 18 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 27. - On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 6. - On the Trail Making Test Part A, her total number of seconds to complete is 27, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 48, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203933841_02143_MR_Sagittal_MP-Rage_br_raw_20230124205938681_I10178482	On a T1-weighted brain MRI of a 54-year-old female subject, we observed: For the cerebral cortex: - limbic cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left) - frontal lobe atrophy (severe on the left, mild on the right), with focal volume loss observed in the following subregions: frontal pole (mild atrophy both left/right), gyrus rectus (mild-to-moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (moderate-to-severe atrophy on the left), sup. frontal gyrus medial segment (moderate atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right), middle frontal gyrus (mild-to-moderate atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the left) and supplementary motor cortex (normal-to-mild atrophy on the left) - occipital lobe maintains its normal morphology without atrophic features - no observable atrophic alterations in the parietal lobe - temporal lobe atrophy (moderate-to-severe on the left, normal on the right), with focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left), temporal pole (moderate-to-severe atrophy on the left) and middle temporal gyrus (normal-to-mild atrophy on the left) - insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and normal-to-mild atrophy on the right), central operculum (normal-to-mild atrophy on the left) and frontal operculum (normal-to-mild atrophy on the left) For the subcortical structures: - pallidum remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the thalamus - caudate atrophy (moderate on the left, normal on the right) - accumbens atrophy (severe on the left, mild on the right) - no signs of atrophy detected in the ventral dc - no evidence of atrophy or degeneration in the hippocampus - amygdala atrophy (severe on the left, normal on the right) - no pathological changes consistent with atrophy detected in the basal forebrain - putamen atrophy (mild on the left, normal on the right) For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (moderate-to-severe on the left, normal on the right) - normal-to-mild enlargement of the external csf - 4th ventricle remains within normal size parameters, with no enlargement detected - lateral ventricle enlargement (mild on the left, normal on the right)	bvFTD	We have the following subject's personal information: - The subject is a female of 54.0 years old. - She has 18.0 years of education (equivalent to master’s degree) - The subject is left-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 27. - On the semantic categorical fluency test, the subject named 7 animals in 60 seconds. She named 10 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 14. - On the Number Span forward test, her longest span forward was 8. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 27, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 68, her number of commission errors is 1, her number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in delusions, apathy or indifference, disinhibition, a mild (noticeable, but not significant) change in agitation or aggression, anxiety, irritability or lability, appetite and eating. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
FTLD_203617026_02621_MR_Sagittal_MP-Rage_br_raw_20230206161609957_I10181581	On a T1-weighted brain MRI of a 69-year-old male subject, we observed: For the ventricles: - inf. lateral ventricle enlargement (severe on the left, mild-to-moderate on the right) - lateral ventricle enlargement (mild on the left, mild-to-moderate on the right) - external csf appears structurally intact, with no evidence of enlargement - normal-to-mild enlargement of the 3rd ventricle - 4th ventricle is free from enlargement or excessive growth For the subcortical structures: - pallidum atrophy (moderate-to-severe on the left, moderate on the right) - caudate atrophy (severe on the left, moderate on the right) - basal forebrain atrophy (normal-to-mild on the left, normal on the right) - amygdala atrophy (normal-to-mild on the left, mild on the right) - thalamus atrophy (mild on the left, normal-to-mild on the right) - hippocampus atrophy (mild on the left, mild-to-moderate on the right) - accumbens atrophy (mild-to-moderate on the left, normal-to-mild on the right) - putamen atrophy (moderate-to-severe on the left, moderate on the right) - ventral dc atrophy (moderate-to-severe on the left, mild on the right) For the cerebral cortex: - no degenerative or atrophic changes noted in the temporal lobe - occipital lobe remains normal, with no signs of tissue loss - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy both left/right) - no observable atrophic alterations in the insular cortex - parietal lobe remains normal, with no signs of tissue loss - frontal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy both left/right) and posterior orbital gyrus (normal-to-mild atrophy both left/right)	PNFA	We have the following subject's personal information: - The subject is a male of 69.0 years old. - He has 12.0 years of education (equivalent to high school or GRE) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 10. - On the semantic categorical fluency test, the subject named 3 animals in 60 seconds. He named 2 vegetables in 60 seconds. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in apathy or indifference, appetite and eating, a mild (noticeable, but not significant) change in agitation or aggression, disinhibition. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 8.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
FTLD_203719527_02721_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177796	On a T1-weighted brain MRI of a 25-year-old female subject, we observed: For the cerebral cortex: - temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy both left/right) - no evidence of atrophy or degeneration in the frontal lobe - parietal lobe appears structurally intact with no atrophic changes - the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle occipital gyrus (mild atrophy on the right) - insular cortex appears structurally intact with no atrophic changes - limbic cortex presents with a healthy appearance, free from atrophy For the subcortical structures: - no evidence of atrophy or degeneration in the hippocampus - amygdala maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the accumbens - thalamus atrophy (normal-to-mild on the left, normal on the right) - no evidence of atrophy or degeneration in the putamen - no observable atrophic alterations in the ventral dc - no evidence of atrophy or degeneration in the basal forebrain - caudate maintains its normal morphology without atrophic features - pallidum appears structurally intact with no atrophic changes For the ventricles: - no abnormal enlargement observed in the 3rd ventricle - the 4th ventricle shows no structural abnormalities indicative of enlargement - no enlargement observed in the lateral ventricle - no enlargement observed in the inf. lateral ventricle - the external csf shows no structural abnormalities indicative of enlargement	CN	We have the following subject's personal information: - The subject is a female of 25.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 26. - On the semantic categorical fluency test, the subject named 35 animals in 60 seconds. She named 15 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 14. - On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 5. - On the Trail Making Test Part A, her total number of seconds to complete is 21, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 46, her number of commission errors is 0, her number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in apathy or indifference. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203120724_01422_MR_Sagittal_MP-Rage_br_raw_20230124211357486_I10178571	On a T1-weighted brain MRI of a 66-year-old male subject, we observed: For the ventricles: - normal-to-mild enlargement of the 3rd ventricle - no enlargement observed in the external csf - inf. lateral ventricle enlargement (normal-to-mild on the left, mild on the right) - the lateral ventricle shows no structural abnormalities indicative of enlargement - no pathological changes consistent with enlargement noted in the 4th ventricle For the subcortical structures: - no signs of atrophy detected in the hippocampus - no degenerative or atrophic changes noted in the putamen - caudate atrophy (normal-to-mild on the left, normal on the right) - no signs of atrophy detected in the accumbens - basal forebrain appears structurally intact with no atrophic changes - no observable atrophic alterations in the amygdala - the ventral dc shows no structural abnormalities indicative of atrophy - pallidum appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the thalamus For the cerebral cortex: - the insular cortex shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the occipital lobe - the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in fusiform gyrus (normal-to-mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and planum temporale (normal-to-mild atrophy on the left) - no observable atrophic alterations in the parietal lobe - the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) - no signs of atrophy detected in the limbic cortex	CN	We have the following subject's personal information: - The subject is a male of 66.0 years old. - He has 20.0 years of education (equivalent to doctorate) - The subject is ambidextrous We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 31 animals in 60 seconds. He named 22 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 26. - On the Number Span forward test, his longest span forward was 9. On the Number Span backward test, his longest span backward was 6. - On the Trail Making Test Part A, his total number of seconds to complete is 17, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 41, his number of commission errors is 0, his number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203927782_02282_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178057	On a T1-weighted brain MRI of a 74-year-old male subject, we observed: For the ventricles: - lateral ventricle enlargement (mild on the left, normal on the right) - inf. lateral ventricle enlargement (severe on the left, mild on the right) - 4th ventricle is free from enlargement or excessive growth - external csf remains within normal size parameters, with no enlargement detected - normal-to-mild enlargement of the 3rd ventricle For the cerebral cortex: - insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left), central operculum (normal-to-mild atrophy on the left) and posterior insula (normal-to-mild atrophy on the left) - no evidence of atrophy or degeneration in the occipital lobe - parietal lobe presents with a healthy appearance, free from atrophy - frontal lobe appears structurally intact with no atrophic changes - limbic cortex atrophy (mild-to-moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) - temporal lobe atrophy (moderate-to-severe on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the left), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) For the subcortical structures: - normal-to-mild bilateral caudate atrophy - normal-to-mild bilateral accumbens atrophy - the basal forebrain shows no structural abnormalities indicative of atrophy - putamen remains normal, with no signs of tissue loss - hippocampus atrophy (moderate on the left, normal-to-mild on the right) - pallidum remains normal, with no signs of tissue loss - no observable atrophic alterations in the ventral dc - amygdala atrophy (severe on the left, mild on the right) - the thalamus shows no structural abnormalities indicative of atrophy	SD	We have the following subject's personal information: - The subject is a male of 74.0 years old. - He has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 2 animals in 60 seconds. He named 0 vegetables in 60 seconds. - On the Number Span forward test, his longest span forward was 3. - On the Trail Making Test Part A, his total number of seconds to complete is 150, his number of commission errors is 3, his number of correct lines is 16. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in depression or dysphoria, anxiety, apathy or indifference, a mild (noticeable, but not significant) change in hallucinations, irritability or lability, motor disturbance. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 3.0, corresponding to severe impairment. His standard CDR sum of boxes is 15.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 3.0 on language, corresponding to severe impairment.
FTLD_203664774_03476_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450825	On a T1-weighted brain MRI of a 76-year-old male subject, we observed: For the cerebral cortex: - no evidence of atrophy or degeneration in the insular cortex - no evidence of atrophy or degeneration in the temporal lobe - no observable atrophic alterations in the occipital lobe - the parietal lobe shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the frontal lobe - limbic cortex remains normal, with no signs of tissue loss For the subcortical structures: - no signs of atrophy detected in the thalamus - the pallidum shows no structural abnormalities indicative of atrophy - the amygdala shows no structural abnormalities indicative of atrophy - basal forebrain presents with a healthy appearance, free from atrophy - normal-to-mild bilateral accumbens atrophy - putamen presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the ventral dc - caudate appears structurally intact with no atrophic changes - hippocampus remains normal, with no signs of tissue loss For the ventricles: - no abnormal enlargement observed in the lateral ventricle - normal-to-mild enlargement of the 4th ventricle - no abnormal enlargement observed in the external csf - normal-to-mild enlargement of the 3rd ventricle - inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right)	PNFA	We have the following subject's personal information: - The subject is a male of 76.0 years old. - He has 16.0 years of education (equivalent to bachelor’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - The subject has a 32-item Multilingual Naming Test (MINT) total score of 24. - On the semantic categorical fluency test, the subject named 13 animals in 60 seconds. He named 10 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 4. - On the Number Span forward test, his longest span forward was 4. On the Number Span backward test, his longest span backward was 3. - On the Trail Making Test Part A, his total number of seconds to complete is 51, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 95, his number of commission errors is 0, his number of correct lines is 24. - In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in motor disturbance, a mild (noticeable, but not significant) change in anxiety. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
FTLD_203945852_01254_MR_Sagittal_MP-Rage_br_raw_20230124210916522_I10178544	On a T1-weighted brain MRI of a 57-year-old female subject, we observed: For the subcortical structures: - no signs of atrophy detected in the caudate - accumbens atrophy (normal-to-mild on the left, normal on the right) - the putamen shows no structural abnormalities indicative of atrophy - amygdala atrophy (normal on the left, normal-to-mild on the right) - pallidum maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the ventral dc - no pathological changes consistent with atrophy detected in the basal forebrain - no pathological changes consistent with atrophy detected in the thalamus - hippocampus remains normal, with no signs of tissue loss For the ventricles: - the lateral ventricle shows no structural abnormalities indicative of enlargement - normal-to-mild enlargement of the external csf - no enlargement observed in the inf. lateral ventricle - no pathological changes consistent with enlargement noted in the 3rd ventricle - mild-to-moderate enlargement of the 4th ventricle For the cerebral cortex: - no degenerative or atrophic changes noted in the occipital lobe - insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy on the right) - normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (mild atrophy on the left), temporal pole (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left) and transverse temporal gyrus (normal-to-mild atrophy on the right) - no evidence of atrophy or degeneration in the parietal lobe - normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left) - no degenerative or atrophic changes noted in the frontal lobe	CN	We have the following subject's personal information: - The subject is a female of 57.0 years old. - She has 16.0 years of education (equivalent to bachelor’s degree) - The subject is left-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 14 animals in 60 seconds. She named 18 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 19. - On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 6. - On the Trail Making Test Part A, her total number of seconds to complete is 18, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 48, her number of commission errors is 0, her number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
FTLD_203965266_03666_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I11047655	On a T1-weighted brain MRI of a 41-year-old male subject, we observed: For the ventricles: - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - no signs of enlargement detected in the 4th ventricle - the external csf shows no structural abnormalities indicative of enlargement - 3rd ventricle maintains its normal volume without signs of enlargement - lateral ventricle appears structurally intact, with no evidence of enlargement For the subcortical structures: - no evidence of atrophy or degeneration in the hippocampus - no observable atrophic alterations in the pallidum - no pathological changes consistent with atrophy detected in the caudate - no pathological changes consistent with atrophy detected in the putamen - thalamus appears structurally intact with no atrophic changes - accumbens maintains its normal morphology without atrophic features - ventral dc presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the amygdala - basal forebrain remains normal, with no signs of tissue loss For the cerebral cortex: - no observable atrophic alterations in the parietal lobe - no signs of atrophy detected in the occipital lobe - no evidence of atrophy or degeneration in the temporal lobe - the insular cortex shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the frontal lobe - no pathological changes consistent with atrophy detected in the limbic cortex	CN	We have the following subject's personal information: - The subject is a male of 41.0 years old. - He has 18.0 years of education (equivalent to master’s degree) - The subject is right-handed We have the following results on the Neuropsychological Test Battery: - On the semantic categorical fluency test, the subject named 16 animals in 60 seconds. He named 12 vegetables in 60 seconds. - On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 17. - On the Number Span forward test, his longest span forward was 6. On the Number Span backward test, his longest span backward was 4. - On the Trail Making Test Part A, his total number of seconds to complete is 17, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 54, his number of commission errors is 0, his number of correct lines is 24. - With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.

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