text: This paper proposes a deep learning (DL) approach (pre-trained CNNs) to the analysis of histopathological images for disease localization. It correctly identifies the problem that DL usually requires large image databases to provide competitive results, while annotated histopathological data repositories are costly to produce and not on that size scale. It also correctly identifies that this is a daunting task for human medical experts and therefore one that could surely benefit from the use of automated methods like the ones proposed. The study seems sound from a technical viewpoint to me and its contribution is incremental, as it builds on existing research, which is correctly identified. Results are not always too impressive, but authors seem intent on making them useful for pathogists in practice (an intention that is always worth the effort). I think the paper would benefit from a more explicit statement of its original contributions (against contextual published research) Minor issues: Revise typos (e.g. title of section 2) Please revise list of references (right now a mess in terms of format, typos, incompleteness